Aquaporin 2 and Apical Calcium-Sensing Receptor: New Players in Polyuric Disorders Associated With Hypercalciuria

Seminars in Nephrology

Volumn 28, Issue 3, 2008, Pages 297-305

  Procino, G ^a   Mastrofrancesco, L ^a   Mira, A ^a   Tamma, G ^a   Carmosino, M ^a   Emma, F ^b   Svelto, M ^a   Valenti, G ^a  

^a UNIVERSITY OF BARI   (Italy)

^b BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

Author keywords

ADH; aquaporin; calcilytic drugs; Calcium sensing receptor; nephrolithiasis; stones

Indexed keywords

AQUAPORIN 2; CALCIUM; CALCIUM SENSING RECEPTOR; SODIUM CHLORIDE; UREA; VASOPRESSIN; VITAMIN D;

ARTICLE; CALCIUM METABOLISM; ELECTROLYTE TRANSPORT; GENE EXPRESSION; GENE MUTATION; GENETIC POLYMORPHISM; HUMAN; HYPERCALCIURIA; HYPOCALCEMIA; INHERITANCE; METABOLIC DISORDER; MINERAL METABOLISM; NEPHROLITHIASIS; NOCTURNAL ENURESIS; NONHUMAN; POLYURIA; PRIORITY JOURNAL; STONE FORMATION; URINARY EXCRETION; WATER ABSORPTION;

AQUAPORIN 2; HOMEOSTASIS; HUMANS; HYPERCALCIURIA; KIDNEY; NOCTURNAL ENURESIS; POLYURIA; RECEPTORS, CALCIUM-SENSING; WATER;

EID: 44349114017     PISSN: 02709295     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2008.03.007     Document Type: Article

References (64)

1. Taylor E.N., and Curhan G.C. Diet and fluid prescription in stone disease. Kidney Int 70 (2006) 835-839
2. Coe F.L., Evan A., and Worcester E. Kidney stone disease. J Clin Invest 115 (2005) 2598-2608
3. Gambaro G., Vezzoli G., Casari G., et al. Genetics of hypercalciuria and calcium nephrolithiasis: from the rare monogenic to the common polygenic forms. Am J Kidney Dis 44 (2004) 963-986
4. Moe O.W., and Bonny O. Genetic hypercalciuria. >J Am Soc Nephrol 16 (2005) 729-745
5. Devuyst O., and Pirson Y. Genetics of hypercalciuric stone forming diseases. Kidney Int 72 (2007) 1065-1072
6. Asplin J.R., Mandel N.S., and Coe F.L. Evidence of calcium phosphate supersaturation in the loop of Henle. Am J Physiol 270 (1996) F604-F613
7. Johnson C.M., Wilson D.M., O'Fallon W.M., et al. Renal stone epidemiology: a 25-year study in Rochester, Minnesota. Kidney Int 16 (1979) 624-631
8. Verkoelen C.F., and Verhulst A. Proposed mechanisms in renal tubular crystal retention. Kidney Int 72 (2007) 13-18
9. Jacobson A.L., Singhal P.C., Mandin H., et al. Urinary ionic calcium and binding sites in normocalciuric idiopathic calcium urolithiasis. Invest Urol 17 (1979) 218-222
10. Strauss A.L., Coe F.L., Deutsch L., et al. Factors that predict relapse of calcium nephrolithiasis during treatment: a prospective study. Am J Med 72 (1982) 17-24
11. Knepper M.A., and Inoue T. Regulation of aquaporin-2 water channel trafficking by vasopressin. Curr Opin Cell Biol 9 (1997) 560-564
12. Klussmann E., Maric K., and Rosenthal W. The mechanisms of aquaporin control in the renal collecting duct. Rev Physiol Biochem Pharmacol 141 (2000) 33-95
13. Brown D. The ins and outs of aquaporin-2 trafficking. Am J Physiol Renal Physiol 284 (2003) F893-F901
14. Valenti G., Procino G., Tamma G., et al. Minireview: aquaporin 2 trafficking. Endocrinology 146 (2005) 5063-5070
15. Knoers N.V., and Deen P.M. Molecular and cellular defects in nephrogenic diabetes insipidus. Pediatr Nephrol 16 (2001) 1146-1152
16. Procino G., Carmosino M., Marin O., et al. Ser-256 phosphorylation dynamics of aquaporin 2 during maturation from the ER to the vesicular compartment in renal cells. FASEB J 17 (2003) 1886-1888
17. Pisitkun T., Johnstone R., and Knepper M.A. Discovery of urinary biomarkers. Mol Cell Proteomics 5 (2006) 1760-1771
18. Kanno K., Sasaki S., Hirata Y., et al. Urinary excretion of aquaporin-2 in patients with diabetes insipidus. N Engl J Med 332 (1995) 1540-1545
19. Deen P.M., van Aubel R.A., van Lieburg A.F., et al. Urinary content of aquaporin 1 and 2 in nephrogenic diabetes insipidus. J Am Soc Nephrol 7 (1996) 836-841
20. Saito T., Ishikawa S.E., Sasaki S., et al. Alteration in water channel AQP-2 by removal of AVP stimulation in collecting duct cells of dehydrated rats. Am J Physiol 272 (1997) F183-F191
21. Murer L., Addabbo F., Carmosino M., et al. Selective decrease in urinary aquaporin 2 and increase in prostaglandin E2 excretion is associated with postobstructive polyuria in human congenital hydronephrosis. J Am Soc Nephrol 15 (2004) 2705-2712
22. Ishikawa S. Urinary excretion of aquaporin-2 in pathological states of water metabolism. Ann Med 32 (2000) 90-93
23. Schrier R.W. Body water homeostasis: clinical disorders of urinary dilution and concentration. J Am Soc Nephrol 17 (2006) 1820-1832
24. Valenti G., Laera A., Pace G., et al. Urinary aquaporin 2 and calciuria correlate with the severity of enuresis in children. J Am Soc Nephrol 11 (2000) 1873-1881
25. Shaer A.J. Inherited primary renal tubular hypokalemic alkalosis: a review of Gitelman and Bartter syndromes. Am J Med Sci 322 (2001) 316-332
26. Sands J.M., Naruse M., Baum M., et al. Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct. J Clin Invest 99 (1997) 1399-1405
27. Sands J.M., Flores F.X., Kato A., et al. Vasopressin-elicited water and urea permeabilities are altered in IMCD in hypercalcemic rats. Am J Physiol 274 (1998) F978-F985
28. Puliyanda D.P., Ward D.T., Baum M.A., et al. Calpain-mediated AQP2 proteolysis in inner medullary collecting duct. Biochem Biophys Res Commun 303 (2003) 52-58
29. Brown E.M., and MacLeod R.J. Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 81 (2001) 239-297
30. Ward D.T., and Riccardi D. Renal physiology of the extracellular calcium-sensing receptor. Pflugers Arch 445 (2002) 169-176
31. Hebert S.C., Brown E.M., and Harris H.W. Role of the Ca(2+)-sensing receptor in divalent mineral ion homeostasis. J Exp Biol 200 (1997) 295-302
32. Pearce S.H., and Thakker R.V. The calcium-sensing receptor: insights into extracellular calcium homeostasis in health and disease. J Endocrinol 154 (1997) 371-378
33. Hofer A.M., and Brown E.M. Extracellular calcium sensing and signalling. Nat Rev Mol Cell Biol 4 (2003) 530-538
34. Alon U.S. Nocturnal enuresis. Pediatr Nephrol 9 (1995) 94-103
35. Mark S.D., and Frank J.D. Nocturnal enuresis. Br J Urol 75 (1995) 427-434
36. Pace G., Aceto G., Cormio L., et al. Nocturnal enuresis can be caused by absorptive hypercalciuria. Scand J Urol Nephrol 33 (1999) 111-114
37. Valenti G., Laera A., Gouraud S., et al. Low-calcium diet in hypercalciuric enuretic children restores AQP2 excretion and improves clinical symptoms. Am J Physiol Renal Physiol 283 (2002) F895-F903
38. Brown E.M., Gamba G., Riccardi D., et al. Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature 366 (1993) 575-580
39. Riccardi D., Lee W.S., Lee K., et al. Localization of the extracellular Ca(2+)-sensing receptor and PTH/PTHrP receptor in rat kidney. Am J Physiol 271 (1996) F951-F956
40. Riccardi D., Park J., Lee W.S., et al. Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor. Proc Natl Acad Sci U S A 92 (1995) 131-135
41. Brown E.M. Physiology and pathophysiology of the extracellular calcium-sensing receptor. Am J Med 106 (1999) 238-253
42. Brown E.M., Chattopadhyay N., Vassilev P.M., et al. The calcium-sensing receptor (CaR) permits Ca2+ to function as a versatile extracellular first messenger. Recent Prog Horm Res 53 (1998) 257-281
43. Procino G., Carmosino M., Tamma G., et al. Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells. Kidney Int 66 (2004) 2245-2255
44. Valenti G., Frigeri A., Ronco P.M., et al. Expression and functional analysis of water channels in a stably AQP2-transfected human collecting duct cell line. J Biol Chem 271 (1996) 24365-24370
45. Bustamante M., Hasler U., and Leroy V. Calcium-sensing receptor attenuates AVP-induced aquaporin-2 expression via a calmodulin-dependent mechanism. J Am Soc Nephrol 19 (2008) 109-116
46. Hasler U., Mordasini D., Bens M., et al. Long term regulation of aquaporin-2 expression in vasopressin-responsive renal collecting duct principal cells. J Biol Chem 277 (2002) 10379-10386
47. Bai M. Structure-function relationship of the extracellular calcium-sensing receptor. Cell Calcium 35 (2004) 197-207
48. Wang W.H., Lu M., and Hebert S.C. Cytochrome P-450 metabolites mediate extracellular Ca(2+)-induced inhibition of apical K+ channels in the TAL. Am J Physiol 271 (1996) C103-C111
49. Pollak M.R., Brown E.M., Chou Y.H., et al. Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell 75 (1993) 1297-1303
50. Ho D.S., Jerkins G.R., Williams M., et al. Ureteropelvic junction obstruction in upper and lower moiety of duplex renal systems. Urology 45 (1995) 503-506
51. Bai M., Quinn S., Trivedi S., et al. Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptor. J Biol Chem 271 (1996) 19537-19545
52. Pollak M.R., Brown E.M., Estep H.L., et al. Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation. Nat Genet 8 (1994) 303-307
53. Pearce S.H., Williamson C., Kifor O., et al. A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor. N Engl J Med 335 (1996) 1115-1122
54. Hendy G.N., D'Souza-Li L., Yang B., et al. Mutations of the calcium-sensing receptor (CASR) in familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. Hum Mutat 16 (2000) 281-296
55. Bai M., Janicic N., Trivedi S., et al. Markedly reduced activity of mutant calcium-sensing receptor with an inserted Alu element from a kindred with familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. J Clin Invest 99 (1997) 1917-1925
56. Lienhardt A., Garabedian M., Bai M., et al. A large homozygous or heterozygous in-frame deletion within the calcium-sensing receptor's carboxylterminal cytoplasmic tail that causes autosomal dominant hypocalcemia. J Clin Endocrinol Metab 85 (2000) 1695-1702
57. Marx S.J., Attie M.F., Stock J.L., et al. Maximal urine-concentrating ability: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. J Clin Endocrinol Metab 52 (1981) 736-740
58. Vargas-Poussou R., Huang C., Hulin P., et al. Functional characterization of a calcium-sensing receptor mutation in severe autosomal dominant hypocalcemia with a Bartter-like syndrome. J Am Soc Nephrol 13 (2002) 2259-2266
59. Vezzoli G., Terranegra A., Arcidiacono T., et al. R990G polymorphism of calcium-sensing receptor does produce a gain-of-function and predispose to primary hypercalciuria. Kidney Int 71 (2007) 1155-1162
60. Vezzoli G., Tanini A., Ferrucci L., et al. Influence of calcium-sensing receptor gene on urinary calcium excretion in stone-forming patients. J Am Soc Nephrol 13 (2002) 2517-2523
61. Hodgkinson A., and Pyrah L.N. The urinary excretion of calcium and inorganic phosphate in 344 patients with calcium stone of renal origin. Br J Surg 46 (1958) 10-18
62. Petrel C., Kessler A., Dauban P., et al. Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain. J Biol Chem 279 (2004) 18990-18997
63. Gowen M., Stroup G.B., Dodds R.A., et al. Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats. J Clin Invest 105 (2000) 1595-1604
64. Dvorak M.M., Siddiqua A., Ward D.T., et al. Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones. Proc Natl Acad Sci U S A 101 (2004) 5140-5145