The effects of 10 years of recombinant human growth hormone (GH) in adult (GH)-deficient patients

Journal of Clinical Endocrinology and Metabolism

Volumn 84, Issue 8, 1999, Pages 2596-2602

  Gibney, J ^a   Wallace, J D ^b   Spinks, T ^c   Schnorr, L ^a   Ranicar, A ^c   Cuneo, R C ^b   Lockhart, S ^c   Burnand, K G ^a   Salomon, F ^a   Sonksen, P H ^a   Russell Jones, D ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b PRINCESS ALEXANDRA HOSPITAL   (Australia)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LOW DENSITY LIPOPROTEIN CHOLESTEROL; POTASSIUM; RECOMBINANT GROWTH HORMONE;

ADULT; ARTICLE; CAROTID ARTERY; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GROWTH HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; INTIMA; LEAN BODY WEIGHT; MALE; MUSCLE MASS; PRIORITY JOURNAL; PSYCHOLOGIC TEST; TOTAL BODY POTASSIUM;

EID: 0033345441     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.84.8.5916     Document Type: Article

References (29)

1. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
2. Beneficial effects of growth hormone treatment in GH-deficient adults
3. Treatment of adults with growth hormone deficiency with recombinant human GH
4. Growth hormone treatment of adults with growth hormone deficiency: Results of a 13-month placebo controlled cross-over study
5. The effect of growth hormone administration in growth hormone deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as body composition
6. Premature mortality due to cardiovascular disease in hypopituitarism
7. Serum lipid levels in growth hormone-deficient men
8. Growth hormone treatment improves serum lipids and lipoproteins in adults with growth hormone deficiency
9. High fibrinogen and plasminogen activator inhibitor activity in growth hormone-deficient adults
10. Quadriceps strength before and after growth hormone replacement in hypopituitary adults: Relationship to changes in lean body mass and IGF-I
11. Decreased psychological well-being in adult patients with growth hormone deficiency
12. Growth hormone treatment of growth hormone-deficient adults results in a marked increase in Lp(a) and HDL cholesterol concentrations
13. The effect of growth hormone replacement on serum lipids, lipoproteins, apolipoproteins and cholesterol precursors in adult growth hormone deficient patients
14. The effects of short and long-term growth hormone replacement therapy in hypopituitary adults on lipid metabolism and carbohydrate tolerance
15. Replacement therapy with biosynthestic human growth hormone in growth hormone-deficient hypopituitary adults
16. Quality of life in adults with growth hormone (GH) deficiency: Response to treatment with recombinant human GH in a placebo-controlled 21-month trial
17. Three years of growth hormone treatment in growth hormone-deficient adults: Near normalization of body composition and physical performance
18. Effects of physiologic growth hormone therapy on bone density and body composition in patients with adult-onset of growth hormone deficiency. A randomized, placebo-controlled trial
19. Growth hormone treatment in growth hormone-deficient adults. I. Effects on muscle mass and strength
20. Cardiovascular effects of growth hormone treatment in growth hormone-deficient adults: Stimulation of the renin-aldosterone system
21. The effect of hyopituitarism on life expectancy
22. Adult growth hormone deficient patients demonstrate heterogenity between childhood onset and adult onset before and during human GH treatment
23. An open 36 month study of lipid changes with growth hormone in adults: Lipid changes following replacement of growth hormone in adult acquired growth hormone deficiency
24. Long-term cardiovascular effects of growth hormone treatment in GH-deficient adults. Preliminary data in a small group of adults
25. Ultrasound-determined intima-media thickness and atherosclerosis. Direct and indirect validation
26. Carotid intima-media thickness: Correlation with the British Regional Heart Study risk score
27. Detection of premature atherosclerosis by high-resolution ultrasonography in sympton-free hypopituitary adults
28. Nitric oxide may mediate the haemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind placebo-controlled study
29. Quality of life, body composition and muscle strength in adult growth hormone deficiciency; The influence of growth hormone replacement therapy for up to 3 years