-
1
-
-
33750336249
-
Healthy immune response to allergens: T regulatory cells and more
-
M. Akdis Healthy immune response to allergens: T regulatory cells and more Curr. Opin. Immunol. 18 2006 738 744
-
(2006)
Curr. Opin. Immunol.
, vol.18
, pp. 738-744
-
-
Akdis, M.1
-
3
-
-
2342497250
-
Type-A CpG oligonucleotides activate exclusively porcine natural interferon-producing cells to secrete interferon-alpha, tumour necrosis factor-alpha and interleukin-12
-
L. Guzylack-Piriou C. Balmelli K.C. McCullough A. Summerfield Type-A CpG oligonucleotides activate exclusively porcine natural interferon-producing cells to secrete interferon-alpha, tumour necrosis factor-alpha and interleukin-12 Immunology 112 2004 28 37
-
(2004)
Immunology
, vol.112
, pp. 28-37
-
-
Guzylack-Piriou, L.1
Balmelli, C.2
McCullough, K.C.3
Summerfield, A.4
-
4
-
-
33748790719
-
TLR9-based immunotherapy for allergic disease
-
T. Hayashi E. Raz TLR9-based immunotherapy for allergic disease Am. J. Med. 119 2006 897.e1 897.e6
-
(2006)
Am. J. Med.
, vol.119
, pp. 897.e1-897.e6
-
-
Hayashi, T.1
Raz, E.2
-
5
-
-
0034619794
-
A toll-like receptor recognizes bacterial DNA
-
H. Hemmi O. Takeuchi T. Kawai T. Kaisho S. Sato H. Sanjo M. Matsumoto K. Hoshino H. Wagner K. Takeda S. Akira A toll-like receptor recognizes bacterial DNA Nature 408 2000 740 745
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
7
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
A. Iwasaki R. Medzhitov Toll-like receptor control of the adaptive immune responses Nat. Immunol. 5 2004 987 995
-
(2004)
Nat. Immunol.
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
9
-
-
33646190155
-
Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy
-
P. Johansen G. Senti J.M. Martinez Gomez T. Storni B.R. von Beust B. Wuthrich A. Bot T.M. Kundig Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy Clin. Exp. Allergy 35 2005 1591 1598
-
(2005)
Clin. Exp. Allergy
, vol.35
, pp. 1591-1598
-
-
Johansen, P.1
Senti, G.2
Martinez Gomez, J.M.3
Storni, T.4
von Beust, B.R.5
Wuthrich, B.6
Bot, A.7
Kundig, T.M.8
-
10
-
-
0035098853
-
Effect of chemical modifications of cytosine and guanosine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships
-
E.R. Kandimalla D. Yu Q. Zhao S. Agrawal Effect of chemical modifications of cytosine and guanosine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships Bioorg. Med. Chem. 9 2001 807 813
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 807-813
-
-
Kandimalla, E.R.1
Yu, D.2
Zhao, Q.3
Agrawal, S.4
-
11
-
-
0037809185
-
Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction progiles
-
E.R. Kandimalla L. Bhagat D. Wang D. Yu F.G. Zhu J. Tang H. Wang P. Huang R. Zhang S. Agrawal Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction progiles Nucleic Acids Res. 31 2003 2393 2400
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2393-2400
-
-
Kandimalla, E.R.1
Bhagat, L.2
Wang, D.3
Yu, D.4
Zhu, F.G.5
Tang, J.6
Wang, H.7
Huang, P.8
Zhang, R.9
Agrawal, S.10
-
12
-
-
10744227784
-
A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif
-
E.R. Kandimalla L. Bhagat F.G. Zhu D. Yu Y.P. Cong D. Wang J.X. Tang J.Y. Tang C.F. Knetter E. Lien S. Agrawal A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif Proc. Natl. Acad. Sci. U.S.A. 100 2003 14303 14308
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 14303-14308
-
-
Kandimalla, E.R.1
Bhagat, L.2
Zhu, F.G.3
Yu, D.4
Cong, Y.P.5
Wang, D.6
Tang, J.X.7
Tang, J.Y.8
Knetter, C.F.9
Lien, E.10
Agrawal, S.11
-
13
-
-
21044444274
-
Immunomodulatory oligonucleotides containing a cytosine-phosphate-2′-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists
-
E.R. Kandimalla L. Bhagat Y. Li D. Yu D. Wang Y.P. Cong S.S. Song J.X. Tang T. Sullivan S. Agrawal Immunomodulatory oligonucleotides containing a cytosine-phosphate-2′-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists Proc. Natl. Acad. Sci. U.S.A. 102 2005 6925 6930
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 6925-6930
-
-
Kandimalla, E.R.1
Bhagat, L.2
Li, Y.3
Yu, D.4
Wang, D.5
Cong, Y.P.6
Song, S.S.7
Tang, J.X.8
Sullivan, T.9
Agrawal, S.10
-
15
-
-
1842631153
-
Immunotherapeutic uses of CpG oligodeoxynucleotides
-
D.M. Klinman Immunotherapeutic uses of CpG oligodeoxynucleotides Nat. Rev. Immunol. 4 2004 249 258
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 249-258
-
-
Klinman, D.M.1
-
16
-
-
0029984358
-
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
-
D.M. Klinman A.K. Yi S.L. Beaucage J. Conover A.M. Krieg CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma Proc. Natl. Acad. Sci. U.S.A. 93 1996 2879 2883
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 2879-2883
-
-
Klinman, D.M.1
Yi, A.K.2
Beaucage, S.L.3
Conover, J.4
Krieg, A.M.5
-
17
-
-
0035370099
-
Now i know my CpGs
-
A.M. Krieg Now i know my CpGs Trends Microbiol. 9 2001 249 252
-
(2001)
Trends Microbiol.
, vol.9
, pp. 249-252
-
-
Krieg, A.M.1
-
18
-
-
33745946911
-
Therapeutic potential of Toll-like receptor 9 activation
-
A.M. Krieg Therapeutic potential of Toll-like receptor 9 activation Nat. Rev. Drug Discov. 5 2006 471 484
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 471-484
-
-
Krieg, A.M.1
-
19
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
E. Latz A. Schoenemeyer A. Visintin K.A. Fitzgerald B.G. Monks C.F. Knetter E. Lien N.J. Nilsen T. Espevik D.T. Golenbock TLR9 signals after translocating from the ER to CpG DNA in the lysosome Nat. Immunol. 5 2004 190 198
-
(2004)
Nat. Immunol.
, vol.5
, pp. 190-198
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
Fitzgerald, K.A.4
Monks, B.G.5
Knetter, C.F.6
Lien, E.7
Nilsen, N.J.8
Espevik, T.9
Golenbock, D.T.10
-
20
-
-
17044399617
-
Oligodeoxynucleotides containing synthetic immunostimulatory motifs augment potent Th1 immune responses to HBsAg in mice
-
Y. Li E.R. Kandimalla D. Yu S. Agrawal Oligodeoxynucleotides containing synthetic immunostimulatory motifs augment potent Th1 immune responses to HBsAg in mice Int. Immunopharmacol. 5 2005 981 991
-
(2005)
Int. Immunopharmacol.
, vol.5
, pp. 981-991
-
-
Li, Y.1
Kandimalla, E.R.2
Yu, D.3
Agrawal, S.4
-
21
-
-
0242556891
-
Toll-like receptors: balancing host resistance with immune tolerance
-
C. Pasare R. Medzhitov Toll-like receptors: balancing host resistance with immune tolerance Curr. Opin. Immunol. 15 2003 677 682
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 677-682
-
-
Pasare, C.1
Medzhitov, R.2
-
22
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+ CD25+ T cell-mediated suppression by dendritic cells
-
C. Pasare R. Medzhitov Toll pathway-dependent blockade of CD4+ CD25+ T cell-mediated suppression by dendritic cells Sci. NY 299 2003 1033 1036
-
(2003)
Sci. NY
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
23
-
-
0017192841
-
Induction or suppression of B cell proliferation and differentiation by phytohemagglutinin or concanavalin A in mouse spleen cell cultures
-
P.F. Piguet H.K. Dewey P. Vassalli Induction or suppression of B cell proliferation and differentiation by phytohemagglutinin or concanavalin A in mouse spleen cell cultures J. Immunol. 117 1976 1817 1823
-
(1976)
J. Immunol.
, vol.117
, pp. 1817-1823
-
-
Piguet, P.F.1
Dewey, H.K.2
Vassalli, P.3
-
25
-
-
33845786018
-
Current and future drugs targeting one class of innate immunity receptors: the toll-like receptors
-
F. Romagne Current and future drugs targeting one class of innate immunity receptors: the toll-like receptors Drug Discov. Today 12 2007 80 87
-
(2007)
Drug Discov. Today
, vol.12
, pp. 80-87
-
-
Romagne, F.1
-
26
-
-
0030240062
-
Macrophages ingest and are activated by bacterial DNA
-
K.J. Stacey M.J. Sweet D.A. Hume Macrophages ingest and are activated by bacterial DNA J. Immunol. 157 1996 2116 2122
-
(1996)
J. Immunol.
, vol.157
, pp. 2116-2122
-
-
Stacey, K.J.1
Sweet, M.J.2
Hume, D.A.3
-
27
-
-
0032995849
-
Bacterial CpG DNA activates immune cells to signal infectious danger
-
H. Wagner Bacterial CpG DNA activates immune cells to signal infectious danger Adv. Immunol. 73 1999 329 368
-
(1999)
Adv. Immunol.
, vol.73
, pp. 329-368
-
-
Wagner, H.1
-
28
-
-
0035252588
-
New trends in immunotherapy to prevent atopic diseases
-
C. Walker C. Zuany-Amorim New trends in immunotherapy to prevent atopic diseases Trends Pharmacol. Sci. 22 2001 84 90
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 84-90
-
-
Walker, C.1
Zuany-Amorim, C.2
-
30
-
-
0032209664
-
Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA
-
A.K. Yi A.M. Krieg Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA J. Immunol. 161 1998 4493 4497
-
(1998)
J. Immunol.
, vol.161
, pp. 4493-4497
-
-
Yi, A.K.1
Krieg, A.M.2
-
31
-
-
0036780681
-
Toll-like receptors as potential therapeutic targets for multiple diseases
-
C. Zuany-Amorim J. Hastewell C. Walker Toll-like receptors as potential therapeutic targets for multiple diseases Nat. Rev. Drug Discov. 1 2002 797 807
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 797-807
-
-
Zuany-Amorim, C.1
Hastewell, J.2
Walker, C.3
|