Isoliquiritigenin, a flavonoid from licorice, relaxes guinea-pig tracheal smooth muscle in vitro and in vivo: Role of cGMP/PKG pathway

European Journal of Pharmacology

Volumn 587, Issue 1-3, 2008, Pages 257-266

  Liu, Bin ^a,b   Yang, Jing ^a   Wen, Qingshan ^b   Li, Ying ^a  

^a WUHAN UNIVERSITY   (China)

^b HUBEI CANCER HOSPITAL   (China)

Author keywords

cGMP; Intracellular Ca2+ concentration; Isoliquiritigenin; K+ channel; Tracheal smooth muscle cell

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 9 (TETRAHYDRO 2 FURYL)ADENINE; ACETYLCHOLINE; AMINOPHYLLINE; APAMIN; CALCIUM; CHARYBDOTOXIN; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; FLAVONOID; GLIBENCLAMIDE; GLYCYRRHIZA GLABRA EXTRACT; HISTAMINE; INDOMETACIN; ISOBUTYLMETHYLXANTHINE; ISOLOQUIRITIGENIN; KT 5823; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; MILRINONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OXYHEMOGLOBIN; PHOSPHODIESTERASE V; POTASSIUM CHLORIDE; PROSTAGLANDIN; ROLIPRAM; ZAPRINAST;

AEROSOL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHODILATATION; BRONCHOSPASM; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GUINEA PIG; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SPACE; ISOMETRICS; LATENT PERIOD; MALE; MICROFLUOROMETRY; MULTICHANNEL RECORDER; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RESPIRATORY AIRFLOW; SIGNAL TRANSDUCTION; SMOOTH MUSCLE RELAXATION; THROMBOCYTE; TRACHEA; TRACHEA MUCOSA; TRACHEA MUSCLE; TREATMENT RESPONSE;

ANIMALS; CALCIUM; CELLS, CULTURED; CHALCONES; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; EPITHELIUM; FEMALE; GLYCYRRHIZA; GUINEA PIGS; ISOMETRIC CONTRACTION; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE; PATCH-CLAMP TECHNIQUES; PHOSPHORIC DIESTER HYDROLASES; PLANT ROOTS; POTASSIUM CHANNELS; PROSTAGLANDINS; TRACHEA;

EID: 44149123055     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.03.015     Document Type: Article

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