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Volumn 123, Issue 4, 1998, Pages 753-761

Relaxant effects of NKH477, a new water-soluble forskolin derivative, on guinea-pig tracheal smooth muscle: The role of Ca2+-activated K+ channels

Author keywords

Airway smooth muscle; Ca2+ activated k+ channels; Histamine; Iberiotoxin; NKH477; Voltage dependent Ca2+ channels

Indexed keywords

BRONCHODILATING AGENT; CALCIUM; CYCLIC AMP; DRUG DERIVATIVE; FORSKOLIN; HISTAMINE; IBERIOTOXIN; ISOPRENALINE; NIFEDIPINE; PEPTIDE; POTASSIUM; POTASSIUM CHANNEL; WATER;

EID: 0031990837     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701655     Document Type: Article
Times cited : (15)

References (36)
  • 1
    • 0022400904 scopus 로고
    • Electrophysiological and other aspects of the relaxant action of isoprenaline in guinea-pig isolated trachealis
    • ALLEN, S.L., BEECH, D.J., FOSTER, R.W., MORGAN, G.P. & SMALL, R.C. (1985). Electrophysiological and other aspects of the relaxant action of isoprenaline in guinea-pig isolated trachealis. Br. J. Pharmacol., 86, 843 - 854.
    • (1985) Br. J. Pharmacol. , vol.86 , pp. 843-854
    • Allen, S.L.1    Beech, D.J.2    Foster, R.W.3    Morgan, G.P.4    Small, R.C.5
  • 2
    • 0022608146 scopus 로고
    • Effects of verapamil on the response of the guinea-pig tracheal muscle to carbachol
    • BABA, K., SATAKE, T., TAKAGI, K. & TOMITA, T. (1986). Effects of verapamil on the response of the guinea-pig tracheal muscle to carbachol. Br. J. Pharmacol., 88, 441 - 449.
    • (1986) Br. J. Pharmacol. , vol.88 , pp. 441-449
    • Baba, K.1    Satake, T.2    Takagi, K.3    Tomita, T.4
  • 3
    • 0025281884 scopus 로고
    • Cardiovascular effects of forskolin (HL 362) in patients with idiopathic congestive cardiomyopathy a comparative study with dobutamine and sodium nitroprusside
    • BAUMAN, G., FELIX, S., SATTELBERGER, U. & KLEIN, G. (1990). Cardiovascular effects of forskolin (HL 362) in patients with idiopathic congestive cardiomyopathy a comparative study with dobutamine and sodium nitroprusside. J. Cardiovasc. Pharmacol., 16, 93 - 100.
    • (1990) J. Cardiovasc. Pharmacol. , vol.16 , pp. 93-100
    • Bauman, G.1    Felix, S.2    Sattelberger, U.3    Klein, G.4
  • 6
    • 0021321488 scopus 로고
    • Increased phosphorylalion of myosin light chain kinase after an increase in cyclic AMP in intact smooth muscle
    • DE LANEROLLE, P., NISHIKAWA, M., YOST, A. & ADELSTEIN, R.S. (1984). Increased phosphorylalion of myosin light chain kinase after an increase in cyclic AMP in intact smooth muscle. Science. 223, 1415 - 1417.
    • (1984) Science , vol.223 , pp. 1415-1417
    • De Lanerolle, P.1    Nishikawa, M.2    Yost, A.3    Adelstein, R.S.4
  • 7
    • 0025299607 scopus 로고
    • Purification and characterizaton of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus
    • GALVEZ, A., GIMENEZ-GALLEGO, G., REUBEN, J.P., ROY-CONTANCIN, L., FEIGENBAUM, P., KACZOROWSKI, G.J. & GARCIA, M.L. (1990). Purification and characterizaton of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. J. Biol. Chem., 265, 11083 - 11090.
    • (1990) J. Biol. Chem. , vol.265 , pp. 11083-11090
    • Galvez, A.1    Gimenez-Gallego, G.2    Reuben, J.P.3    Roy-Contancin, L.4    Feigenbaum, P.5    Kaczorowski, G.J.6    Garcia, M.L.7
  • 8
    • 84990447291 scopus 로고
    • Characterization of the vasodilator effects of NKH477, a novel forskolin derivative, in isolated rat and dog arteries
    • HIMETA, M., HOSONO, M., FUJIHARA, R. & NAKAMURA, K. (1991). Characterization of the vasodilator effects of NKH477, a novel forskolin derivative, in isolated rat and dog arteries. Jpn. J. Pharmacol. (Suppl 1), 55, 171.
    • (1991) Jpn. J. Pharmacol. (Suppl 1) , vol.55 , pp. 171
    • Himeta, M.1    Hosono, M.2    Fujihara, R.3    Nakamura, K.4
  • 9
    • 0027936832 scopus 로고
    • Role of calcium-activated potassium channels in the relaxation of tracheal smooth muscles by forskolin
    • HIRAMATSU, T., KUME, H., KOTLIKOFF, M.I. & TAKAGI, K. (1994). Role of calcium-activated potassium channels in the relaxation of tracheal smooth muscles by forskolin. Clin. Exp. Pharmacol. Physiol., 21, 367 - 375.
    • (1994) Clin. Exp. Pharmacol. Physiol. , vol.21 , pp. 367-375
    • Hiramatsu, T.1    Kume, H.2    Kotlikoff, M.I.3    Takagi, K.4
  • 10
    • 0022553686 scopus 로고
    • Effects of relaxants on electrical and mechanical activities in the guinea-pig tracheal muscle
    • HONDA, K., SATAKE, T., TAKAGI, K. & TOMITA, T. (1986). Effects of relaxants on electrical and mechanical activities in the guinea-pig tracheal muscle. Br. J. Pharmacol., 87, 665 - 671.
    • (1986) Br. J. Pharmacol. , vol.87 , pp. 665-671
    • Honda, K.1    Satake, T.2    Takagi, K.3    Tomita, T.4
  • 11
    • 0026520747 scopus 로고
    • Cardiovascular and adenylate cyclase stimulant properties of NKH477, a novel water-soluble forskolin derivative
    • HOSONO, M., TAKAHIRA, T., FUJITA, A., FUJIWARA, R., ISHIZUKA, O., TATEE, T. & NAKAMURA, K. (1992). Cardiovascular and adenylate cyclase stimulant properties of NKH477, a novel water-soluble forskolin derivative. J. Cardiovasc. Pharmacol., 19, 625 - 634.
    • (1992) J. Cardiovasc. Pharmacol. , vol.19 , pp. 625-634
    • Hosono, M.1    Takahira, T.2    Fujita, A.3    Fujiwara, R.4    Ishizuka, O.5    Tatee, T.6    Nakamura, K.7
  • 13
    • 0029968554 scopus 로고    scopus 로고
    • + channel inhibitors on the electrical behaviour of guinea-pig isolated trachealis and on its response to spasmogenic drugs
    • + channel inhibitors on the electrical behaviour of guinea-pig isolated trachealis and on its response to spasmogenic drugs. Br. J. Pharmacol., 117, 1653 - 1662.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1653-1662
    • Isaac, L.1    McArdle, S.2    Miller, N.M.3    Foster, R.W.4    Small, R.C.5
  • 14
    • 0027138851 scopus 로고
    • 2+ mobilization in smooth muscle of rabbit mesenteric artery
    • 2+ mobilization in smooth muscle of rabbit mesenteric artery. Br. J. Pharmacol., 110, 1117 - 1125.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 1117-1125
    • Ito, S.1    Suzuki, S.2    Itoh, T.3
  • 16
    • 0027154617 scopus 로고
    • Interaction of iberiotoxin with β-adrenoceptor agonists and sodium nitroprusside on guinea pig trachea
    • JONES, T.R., CHARETTE, L., GARCIA, M.L. & KACZOROWSKI, G.J. (1993). Interaction of iberiotoxin with β-adrenoceptor agonists and sodium nitroprusside on guinea pig trachea. J. Appl. Physiol., 74, 1879 - 1884.
    • (1993) J. Appl. Physiol. , vol.74 , pp. 1879-1884
    • Jones, T.R.1    Charette, L.2    Garcia, M.L.3    Kaczorowski, G.J.4
  • 18
    • 0026448005 scopus 로고
    • Stimulatory and inhibitory regulation of calcium-activated potassium channels by guanine nucleotide-binding proteins
    • KUME, H., GRAZIANO, M.P. & KOTLIKOFF, M.I. (1992). Stimulatory and inhibitory regulation of calcium-activated potassium channels by guanine nucleotide-binding proteins. Proc. Natl. Acad. Sci. U.S.A., 89, 11051 - 11055.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 11051-11055
    • Kume, H.1    Graziano, M.P.2    Kotlikoff, M.I.3
  • 20
    • 0031225299 scopus 로고    scopus 로고
    • Inhibitory effects of G, on desensitization of β-adrenergic receptors in tracheal smooth muscle
    • KUME, H. & TAKAGI, K. (1997). Inhibitory effects of G, on desensitization of β-adrenergic receptors in tracheal smooth muscle. Am. J. Physiol., 273, L556 - L564.
    • (1997) Am. J. Physiol. , vol.273
    • Kume, H.1    Takagi, K.2
  • 21
    • 0024472766 scopus 로고
    • +-channel activity in tracheal myocytes by phosphorylation
    • +-channel activity in tracheal myocytes by phosphorylation. Nature, 341, 152 - 154.
    • (1989) Nature , vol.341 , pp. 152-154
    • Kume, H.1    Takai, A.2    Tokuno, H.3    Tomita, T.4
  • 22
    • 0027409361 scopus 로고
    • Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis
    • LAURENT, F., MICHEL, A., BONNET, P.A., CHAPAT, J.P. & BOUCARD, M. (1993). Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis. Br. J. Pharmacol., 108, 622 - 626.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 622-626
    • Laurent, F.1    Michel, A.2    Bonnet, P.A.3    Chapat, J.P.4    Boucard, M.5
  • 23
    • 0022555591 scopus 로고
    • Calcium-activated potassium channels in canine airway smooth muscle
    • MCCANN, J.D. & WELSH, M.J. (1986). Calcium-activated potassium channels in canine airway smooth muscle. J. Physiol., 372, 113 - 127.
    • (1986) J. Physiol. , vol.372 , pp. 113-127
    • Mccann, J.D.1    Welsh, M.J.2
  • 25
    • 0020681099 scopus 로고
    • Relaxant effects of forskolin in smooth muscle. Role of cyclic AMP
    • MULLER, M.J. & BAER, H.P. (1983). Relaxant effects of forskolin in smooth muscle. Role of cyclic AMP. Naunyn-Schmiedeberg's Arch. Pharmacol., 322, 78 - 82.
    • (1983) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.322 , pp. 78-82
    • Muller, M.J.1    Baer, H.P.2
  • 27
    • 0023499821 scopus 로고
    • Simultaneous recordings of calcium signals and mechanical activity using fluorescent dye fura 2 in isolated strips of vascular smooth muscle
    • OZAKI H., SATO, K., SATOH, T. & KARAKI, H. (1987). Simultaneous recordings of calcium signals and mechanical activity using fluorescent dye fura 2 in isolated strips of vascular smooth muscle. Jpn. J. Pharmacol., 45, 429 - 433.
    • (1987) Jpn. J. Pharmacol. , vol.45 , pp. 429-433
    • Ozaki, H.1    Sato, K.2    Satoh, T.3    Karaki, H.4
  • 29
    • 0019811368 scopus 로고
    • Forskolin: A unique diterpene activator of cyclic AMP-generating systems
    • SEAMON, K.B. & DALY, J.W. (1981). Forskolin: a unique diterpene activator of cyclic AMP-generating systems. J. Cyclic Nucleotide Res., 4, 201 - 224.
    • (1981) J. Cyclic Nucleotide Res. , vol.4 , pp. 201-224
    • Seamon, K.B.1    Daly, J.W.2
  • 30
    • 0026716538 scopus 로고
    • Mechanisms of vasodilation induced by NKH477, a water-soluble forskolin derivative, in smooth muscle of the porcine coronary artery
    • SHAFIQ, J., SUZUKI, S., ITOH, T. & KURIYAMA, H. (1992). Mechanisms of vasodilation induced by NKH477, a water-soluble forskolin derivative, in smooth muscle of the porcine coronary artery. Circ. Res., 71, 70 - 81.
    • (1992) Circ. Res. , vol.71 , pp. 70-81
    • Shafiq, J.1    Suzuki, S.2    Itoh, T.3    Kuriyama, H.4
  • 32
    • 0023772326 scopus 로고
    • Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line
    • STURGESS, N.C., KOZLOWSKI, R.Z., CARRINGTON, C.A., HALES, C.N. & ASHFORD, M.L.J. (1988). Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line. Br. J. Pharmacol., 95, 83 - 94.
    • (1988) Br. J. Pharmacol. , vol.95 , pp. 83-94
    • Sturgess, N.C.1    Kozlowski, R.Z.2    Carrington, C.A.3    Hales, C.N.4    Ashford, M.L.J.5
  • 34
    • 0008010375 scopus 로고
    • Electrophysiology of potassium channels in airway smooth muscle
    • ed. Raeburn, D. & Giembycz, M.A. Basel: Birkhäuser Verlag
    • TOMITA, T. & KUME, H. (1994). Electrophysiology of potassium channels in airway smooth muscle. In Airways Smooth Muscle: Development and Regulation of Contractility. ed. Raeburn, D. & Giembycz, M.A. pp 163 - 184, Basel: Birkhäuser Verlag.
    • (1994) Airways Smooth Muscle: Development and Regulation of Contractility , pp. 163-184
    • Tomita, T.1    Kume, H.2
  • 35
    • 0001887259 scopus 로고
    • Cyclic AMP and the control of airways smooth muscle tone
    • ed. Raeburn, D. & Giembycz, M.A. Basel: Birkhäuser Verlag
    • TORPHY, T.J. & HALL, I.P. (1994). Cyclic AMP and the control of airways smooth muscle tone. In Airways Smooth Muscle: Biochemical Control of Contraction and Relaxation. ed. Raeburn, D. & Giembycz, M.A. pp. 215 - 232, Basel: Birkhäuser Verlag.
    • (1994) Airways Smooth Muscle: Biochemical Control of Contraction and Relaxation , pp. 215-232
    • Torphy, T.J.1    Hall, I.P.2
  • 36
    • 0023195884 scopus 로고
    • Relaxant effects of forskolin on guinea pig tracheal smooth muscle
    • TSUKAWAKI, M., SUZUKI, K., SUZUKI, R., TAKAGI, K. & SATAKE, T. (1987). Relaxant effects of forskolin on guinea pig tracheal smooth muscle. Lung, 165, 225 - 237.
    • (1987) Lung , vol.165 , pp. 225-237
    • Tsukawaki, M.1    Suzuki, K.2    Suzuki, R.3    Takagi, K.4    Satake, T.5


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