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Volumn 19, Issue 5, 2008, Pages 863-870

A bench to bedside view of uremic toxins

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANIDINE DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA; UREMIC TOXIN; TOXIN;

EID: 44049106323     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2007121377     Document Type: Review
Times cited : (279)

References (80)
  • 1
    • 0032838784 scopus 로고    scopus 로고
    • Pathophysiologic effects of uremic retention solutes
    • Vanholder R, De Smet R: Pathophysiologic effects of uremic retention solutes. J Am Soc Nephrol 10: 1815-1823, 1999
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1815-1823
    • Vanholder, R.1    De Smet, R.2
  • 4
    • 34548310368 scopus 로고    scopus 로고
    • The glomerular filtration rate in an apparently healthy population and its relation with cardiovascular mortality during 10 years
    • Van Biesen W, De Bacquer D, Verbeke F, Delanghe J, Lameire N, Vanholder R: The glomerular filtration rate in an apparently healthy population and its relation with cardiovascular mortality during 10 years. Eur Heart J 28: 478-483, 2007
    • (2007) Eur Heart J , vol.28 , pp. 478-483
    • Van Biesen, W.1    De Bacquer, D.2    Verbeke, F.3    Delanghe, J.4    Lameire, N.5    Vanholder, R.6
  • 7
    • 48849087575 scopus 로고    scopus 로고
    • The middle molecule hypothesis 30 years after: Lost and rediscovered in the universe of uremic toxicity?
    • in press
    • Vanholder R, Van Laecke S, Glorieux G: The middle molecule hypothesis 30 years after: Lost and rediscovered in the universe of uremic toxicity? J Nephrol 2008, in press
    • (2008) J Nephrol
    • Vanholder, R.1    Van Laecke, S.2    Glorieux, G.3
  • 8
    • 0026651921 scopus 로고
    • Extraction of protein bound ligands from azotemic sera: Comparison of 12 deproteinization methods
    • Vanholder R, Hoefliger N, De Smet R, Ringoir S: Extraction of protein bound ligands from azotemic sera: Comparison of 12 deproteinization methods. Kidney Int 41: 1707-1712, 1992
    • (1992) Kidney Int , vol.41 , pp. 1707-1712
    • Vanholder, R.1    Hoefliger, N.2    De Smet, R.3    Ringoir, S.4
  • 12
    • 0035017739 scopus 로고    scopus 로고
    • Glucose-modified proteins modulate essential functions and apoptosis of polymorphonuclear leukocytes
    • Cohen G, Rudnicki M, Walter F, Niwa T, Horl WH: Glucose-modified proteins modulate essential functions and apoptosis of polymorphonuclear leukocytes. J Am Soc Nephrol 12: 1264-1271, 2001
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1264-1271
    • Cohen, G.1    Rudnicki, M.2    Walter, F.3    Niwa, T.4    Horl, W.H.5
  • 16
    • 0037407239 scopus 로고    scopus 로고
    • Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins
    • D'Hooge R, Van de Vijver G, Van Bogaert PP, Marescau B, Vanholder R, De Deyn PP: Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins. Kidney Int 63: 1764-1775, 2003
    • (2003) Kidney Int , vol.63 , pp. 1764-1775
    • D'Hooge, R.1    Van de Vijver, G.2    Van Bogaert, P.P.3    Marescau, B.4    Vanholder, R.5    De Deyn, P.P.6
  • 17
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance P, Leone A, Calver A, Collier J, Moncada S: Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 339: 572-575, 1992
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3    Collier, J.4    Moncada, S.5
  • 21
    • 23044487722 scopus 로고    scopus 로고
    • Gas chromatographic-mass spectrometric analysis for measurement of p-cresol and its conjugated metabolites in uremic and normal serum
    • De Loor H, Bammens B, Evenepoel P, De Preter V, Verbeke K: Gas chromatographic-mass spectrometric analysis for measurement of p-cresol and its conjugated metabolites in uremic and normal serum. Clin Chem 51: 1535-1538, 2005
    • (2005) Clin Chem , vol.51 , pp. 1535-1538
    • De Loor, H.1    Bammens, B.2    Evenepoel, P.3    De Preter, V.4    Verbeke, K.5
  • 24
    • 33745790096 scopus 로고    scopus 로고
    • Folic acid inhibits homocysteine-induced super-oxide anion production and nuclear factor kappa B activation in macrophages
    • Au-Yeung KK, Yip JC, Siow YL, O K: Folic acid inhibits homocysteine-induced super-oxide anion production and nuclear factor kappa B activation in macrophages. Can J Physiol Pharmacol 84: 141-147, 2006
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 141-147
    • Au-Yeung, K.K.1    Yip, J.C.2    Siow3    YL, O.K.4
  • 26
    • 0031779463 scopus 로고    scopus 로고
    • Characterization of dimethylguanosine, phenylethylamine, and phenylacetic acid as inhibitors of Ca2+ AT-Pase in end-stage renal failure
    • Jankowski J, Luftmann H, Tepel M, Leibfritz D, Zidek W, Schluter H: Characterization of dimethylguanosine, phenylethylamine, and phenylacetic acid as inhibitors of Ca2+ AT-Pase in end-stage renal failure. J Am Soc Nephrol 9: 1249-1257, 1998
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1249-1257
    • Jankowski, J.1    Luftmann, H.2    Tepel, M.3    Leibfritz, D.4    Zidek, W.5    Schluter, H.6
  • 28
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R: Atherosclerosis: An inflammatory disease. N Engl J Med 340: 115-126, 1999
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 29
    • 0029037275 scopus 로고
    • Vascular endothelial cell function and cardiovascular risk factors in patients with chronic renal failure
    • Haaber AB, Eidemak I, Jensen T, Feldt-Rasmussen B, Strandgaard S: Vascular endothelial cell function and cardiovascular risk factors in patients with chronic renal failure. J Am Soc Nephrol 5: 1581-1584, 1995
    • (1995) J Am Soc Nephrol , vol.5 , pp. 1581-1584
    • Haaber, A.B.1    Eidemak, I.2    Jensen, T.3    Feldt-Rasmussen, B.4    Strandgaard, S.5
  • 30
    • 0033839987 scopus 로고    scopus 로고
    • Evidence in vivo showing increase of baseline nitric oxide generation and impairment of endothelium-dependent vasodilation in normotensive patients on chronic hemodialysis
    • Passauer J, Bussemaker E, Range U, Plug M, Gross P: Evidence in vivo showing increase of baseline nitric oxide generation and impairment of endothelium-dependent vasodilation in normotensive patients on chronic hemodialysis. J Am Soc Nephrol 11: 1726-1734, 2000
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1726-1734
    • Passauer, J.1    Bussemaker, E.2    Range, U.3    Plug, M.4    Gross, P.5
  • 31
    • 4344600477 scopus 로고    scopus 로고
    • Effect of advanced glycation end-products on gene expression and synthesis of TNF-alpha and endothelial nitric oxide synthase by endothelial cells
    • Rashid G, Benchetrit S, Fishman D, Bernheim J: Effect of advanced glycation end-products on gene expression and synthesis of TNF-alpha and endothelial nitric oxide synthase by endothelial cells. Kidney Int 66: 1099-1106, 2004
    • (2004) Kidney Int , vol.66 , pp. 1099-1106
    • Rashid, G.1    Benchetrit, S.2    Fishman, D.3    Bernheim, J.4
  • 32
    • 34047159358 scopus 로고    scopus 로고
    • Acute hyperhomocysteinemia induces microvascular and macrovascular endothelial dysfunction
    • Abahji TN, Mill L, lde N, Keller C, Hoffmann U, Weiss N: Acute hyperhomocysteinemia induces microvascular and macrovascular endothelial dysfunction. Arch Med Res 38: 411-416, 2007
    • (2007) Arch Med Res , vol.38 , pp. 411-416
    • Abahji, T.N.1    Mill, L.2    lde, N.3    Keller, C.4    Hoffmann, U.5    Weiss, N.6
  • 34
    • 34047111681 scopus 로고    scopus 로고
    • Circulating microparticles: Pathophysiology and clinical implications
    • Piccin A, Murphy WG, Smith OP: Circulating microparticles: Pathophysiology and clinical implications. Blood Rev 21: 157-171, 2007
    • (2007) Blood Rev , vol.21 , pp. 157-171
    • Piccin, A.1    Murphy, W.G.2    Smith, O.P.3
  • 38
    • 33644871364 scopus 로고    scopus 로고
    • Influence of cardiovascular risk factors on endothelial progenitor cells: Limitations for therapy?
    • Werner N, Nickenig G: Influence of cardiovascular risk factors on endothelial progenitor cells: Limitations for therapy? Arterioscler Thromb Vasc Biol 26: 257-266, 2006
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 257-266
    • Werner, N.1    Nickenig, G.2
  • 39
    • 4143052506 scopus 로고    scopus 로고
    • Endothelial progenitor cells: Characterization and role in vascular biology
    • Urbich C, Dimmeler S: Endothelial progenitor cells: Characterization and role in vascular biology. Circ Res 95: 343-353, 2004
    • (2004) Circ Res , vol.95 , pp. 343-353
    • Urbich, C.1    Dimmeler, S.2
  • 45
    • 0020285201 scopus 로고
    • Abundant amounts of diadenosine 5′,5‴-P1, P4-tetraphosphate are present, releasable, but metabolically inactive, in human platelets
    • Flodgaard H, Klenow H: Abundant amounts of diadenosine 5′,5‴-P1, P4-tetraphosphate are present, releasable, but metabolically inactive, in human platelets. Biochem J 208: 737-742, 1982
    • (1982) Biochem J , vol.208 , pp. 737-742
    • Flodgaard, H.1    Klenow, H.2
  • 46
    • 0020508726 scopus 로고
    • The presence of diadenosine 5′,5‴-P1, P3-triphosphate (Ap3A) in human platelets
    • Luthje J, Ogilvie A: The presence of diadenosine 5′,5‴-P1, P3-triphosphate (Ap3A) in human platelets. Biochem Biophys Res Commun 115: 253-260, 1983
    • (1983) Biochem Biophys Res Commun , vol.115 , pp. 253-260
    • Luthje, J.1    Ogilvie, A.2
  • 49
    • 0036073318 scopus 로고    scopus 로고
    • Vasoactivity of diadenosine polyphosphates in human small mesenteric resistance arteries
    • Steinmetz M, Janssen AK, Pelster F, Rahn KH, Schlatter E: Vasoactivity of diadenosine polyphosphates in human small mesenteric resistance arteries. J Pharmacol Exp Ther 302: 787-794, 2002
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 787-794
    • Steinmetz, M.1    Janssen, A.K.2    Pelster, F.3    Rahn, K.H.4    Schlatter, E.5
  • 51
    • 0037262094 scopus 로고    scopus 로고
    • The AN69 hemofiltration membrane has a decreasing effect on the intracellular diadenosine pentaphosphate concentration of platelets
    • Jankowski J, Schluter H, Henning L, van der Giet M, Jankowski V, Zidek W, Tepel M: The AN69 hemofiltration membrane has a decreasing effect on the intracellular diadenosine pentaphosphate concentration of platelets. Kidney Blood Press Res 26: 50-54, 2003
    • (2003) Kidney Blood Press Res , vol.26 , pp. 50-54
    • Jankowski, J.1    Schluter, H.2    Henning, L.3    van der Giet, M.4    Jankowski, V.5    Zidek, W.6    Tepel, M.7
  • 54
    • 34447649369 scopus 로고    scopus 로고
    • Complex compartmental behavior of small water-soluble uremic retention solutes: Evaluation by direct measurements in plasma and erythrocytes
    • Eloot S, Torremans A, De Smet R, Marescau B, De Deyn PP, Verdonck P, Vanholder R: Complex compartmental behavior of small water-soluble uremic retention solutes: Evaluation by direct measurements in plasma and erythrocytes. Am J Kidney Dis 50: 279-288, 2007
    • (2007) Am J Kidney Dis , vol.50 , pp. 279-288
    • Eloot, S.1    Torremans, A.2    De Smet, R.3    Marescau, B.4    De Deyn, P.P.5    Verdonck, P.6    Vanholder, R.7
  • 58
    • 33846638745 scopus 로고    scopus 로고
    • Dialyzer membrane characteristics and outcome of patients with type 2 diabetes on maintenance hemodialysis
    • Krane V, Krieter DH, Olschewski M, Marz W, Mann JF, Ritz E, Wanner C: Dialyzer membrane characteristics and outcome of patients with type 2 diabetes on maintenance hemodialysis. Am J Kidney Dis 49: 267-275, 2007
    • (2007) Am J Kidney Dis , vol.49 , pp. 267-275
    • Krane, V.1    Krieter, D.H.2    Olschewski, M.3    Marz, W.4    Mann, J.F.5    Ritz, E.6    Wanner, C.7
  • 59
    • 85190669367 scopus 로고    scopus 로고
    • Membrane permeability outcome: Results from the MPO study
    • Barcelona, Spain, June 21-24
    • Locatelli F: Membrane permeability outcome: results from the MPO study. ERA-EDTA meeting, Barcelona, Spain, June 21-24, 2007
    • (2007) ERA-EDTA meeting
    • Locatelli, F.1
  • 60
    • 85190703975 scopus 로고    scopus 로고
    • The membrane permeability outcome (MPO) study
    • San Francisco, CA, November 2-5
    • Locatelli F: The membrane permeability outcome (MPO) study. ASN meeting, San Francisco, CA, November 2-5, 2007
    • (2007) ASN meeting
    • Locatelli, F.1
  • 65
    • 0036329759 scopus 로고    scopus 로고
    • Behavior of non-protein-bound and protein-bound uremic solutes during daily hemodialysis
    • Fagugli RM, De Smet R, Buoncristiani U, Lameire N, Vanholder R: Behavior of non-protein-bound and protein-bound uremic solutes during daily hemodialysis. Am J Kidney Dis 40: 339-347, 2002
    • (2002) Am J Kidney Dis , vol.40 , pp. 339-347
    • Fagugli, R.M.1    De Smet, R.2    Buoncristiani, U.3    Lameire, N.4    Vanholder, R.5
  • 66
    • 33646149394 scopus 로고    scopus 로고
    • Resistance to intercompartmental mass transfer limits beta2-microglobulin removal by post-dilution hemodiafiltration
    • Ward RA, Greene T, Hartmann B, Samtleben W: Resistance to intercompartmental mass transfer limits beta2-microglobulin removal by post-dilution hemodiafiltration. Kidney Int 69: 1431-1437, 2006
    • (2006) Kidney Int , vol.69 , pp. 1431-1437
    • Ward, R.A.1    Greene, T.2    Hartmann, B.3    Samtleben, W.4
  • 68
    • 0034839085 scopus 로고    scopus 로고
    • Effects of ultrapure dialysis fluid on nutritional status and inflammatory parameters
    • Schiffl H, Lang SM, Stratakis D, Fischer R: Effects of ultrapure dialysis fluid on nutritional status and inflammatory parameters. Nephrol Dial Transplant 16: 1863-1869, 2001
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1863-1869
    • Schiffl, H.1    Lang, S.M.2    Stratakis, D.3    Fischer, R.4
  • 69
    • 36048947579 scopus 로고    scopus 로고
    • Identification of central venous hemodialysis catheter-related infection by a semiquantitative culture method
    • Brodersen HP, Beckers B, Clauss M, Vom DJ, Floege J, Janssen U: Identification of central venous hemodialysis catheter-related infection by a semiquantitative culture method. J Nephrol 20: 462-467, 2007
    • (2007) J Nephrol , vol.20 , pp. 462-467
    • Brodersen, H.P.1    Beckers, B.2    Clauss, M.3    Vom, D.J.4    Floege, J.5    Janssen, U.6
  • 70
    • 0026099093 scopus 로고
    • Phagocytosis in uremic and hemodialysis patients: A prospective and cross sectional study
    • Vanholder R, Ringoir S, Dhondt A, Hakim R: Phagocytosis in uremic and hemodialysis patients: A prospective and cross sectional study. Kidney Int 39: 320-327, 1991
    • (1991) Kidney Int , vol.39 , pp. 320-327
    • Vanholder, R.1    Ringoir, S.2    Dhondt, A.3    Hakim, R.4
  • 71
    • 7344229311 scopus 로고    scopus 로고
    • Control of serum phosphate without any phosphate binders in patients treated with nocturnal hemodial-ysis
    • Mucsi I, Hercz G, Uldall R, Ouwendyk M, Francoeur R, Pierratos A: Control of serum phosphate without any phosphate binders in patients treated with nocturnal hemodial-ysis. Kidney Int 53: 1399-1404, 1998
    • (1998) Kidney Int , vol.53 , pp. 1399-1404
    • Mucsi, I.1    Hercz, G.2    Uldall, R.3    Ouwendyk, M.4    Francoeur, R.5    Pierratos, A.6
  • 78
    • 0033798494 scopus 로고    scopus 로고
    • Hemolipodialysis attenuates oxidative stress and removes hydrophobia toxins
    • Wratten ML, Sereni L, Tetta C: Hemolipodialysis attenuates oxidative stress and removes hydrophobia toxins. Artif Organs 24: 685-690, 2000
    • (2000) Artif Organs , vol.24 , pp. 685-690
    • Wratten, M.L.1    Sereni, L.2    Tetta, C.3
  • 80
    • 0029834566 scopus 로고    scopus 로고
    • Inhibition of the accumulation of uremic toxins in the blood and their precursors in the feces after oral administration of Lebenin, a lactic acid bacteria preparation, to uremic patients undergoing hemodialysis
    • Hida M, Aiba Y, Sawamura S, Suzuki N, Satoh T, Koga Y: Inhibition of the accumulation of uremic toxins in the blood and their precursors in the feces after oral administration of Lebenin, a lactic acid bacteria preparation, to uremic patients undergoing hemodialysis. Nephron 74: 349-355, 1996
    • (1996) Nephron , vol.74 , pp. 349-355
    • Hida, M.1    Aiba, Y.2    Sawamura, S.3    Suzuki, N.4    Satoh, T.5    Koga, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.