Gastroprotective activity of the chloroform extract of the roots from Arctium lappa L.

Journal of Pharmacy and Pharmacology

Volumn 60, Issue 6, 2008, Pages 795-801

  Dos Santos, Ana C ^a   Baggio, Cristiane H ^a   Freitas, Cristina S ^a   Lepieszynski, Juliana ^a   Mayer, Bárbara ^a   Twardowschy, André ^a   Missau, Fabiana C ^b   Dos Santos, Élide P ^a   Pizzolatti, Moacir G ^b   Marques, Maria Consuelo Andrade ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ACETIC ACID; ALCOHOL; ARCTIUM LAPPA EXTRACT; ASCORBIC ACID; ATROPINE; FREE RADICAL; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; METOCLOPRAMIDE; OMEPRAZOLE; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARCTIUM LAPPA; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GASTROINTESTINAL MOTILITY; MEDICINAL PLANT; NONHUMAN; RAT; STOMACH ACID SECRETION; STOMACH PH; STOMACH PROTECTION; STOMACH ULCER;

ANIMALS; ANTI-ULCER AGENTS; ARCTIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FREE RADICAL SCAVENGERS; GASTRIC ACID; GASTRIC MUCOSA; GASTROINTESTINAL MOTILITY; H(+)-K(+)-EXCHANGING ATPASE; MEDICINE, TRADITIONAL; MICE; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, WISTAR; STOMACH ULCER;

EID: 43949093423     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.60.6.0016     Document Type: Article

References (37)

1. Abdel-Salam, O. M., Czimmer, J., Debreceni, A., Szolcsányi, J., Mózsik, G. (2001) Gastric mucosal integrity: gastric mucosal blood flow and microcirculation. An overview. J. Physiol. Paris 95: 105-127
2. Baggio, C. H., Otofuji, G. M., Souza, W. M., Santos, C. A. M., Torres, L. M. B., Rieck, L., Marques, M. C. A., Mesia-Vela, S. (2005) Gastroprotective mechanisms of indole alkaloids from Himatanthus lancifolius. Planta Med. 71: 733-738
3. Blois, M. S. (1958) Antioxidant determinations by the use of a stable free radical. Nature 181: 1199-1200
4. Chen, F. A., Wu, A. B., Chen, C. Y. (2004) The influence of treatments on the free radical scavenging activity of burdock and variations of its active. Food Chem. 86: 479-484
5. Dinis, T. C., Santosa, C. L., Almeida, L. M. (2002) The apoprotein is the preferential target for peroxynitrite-induced LDL damage protection by dietary phenolic acids. Free Radic. Res. 36: 531-543
6. Fiske, C. H., Subbarow, Y. (1925) The colorimetric determination of phosphorus. J. Biol. Chem. 66: 375-400
7. Gentil, M., Pereira, J. V., Sousa, Y. T. C. S., Pietro, R., Neto, M. D. S., Vansan, L. P., França, S. C. (2006) In vitro evaluation of the antibacterial activity of Arctium lappa as a phytotherapeutic agent used in intracanal dressings. Phytother. Res. 20: 184-186
8. Hamaishi, K., Kojima, R., Ito, M. (2006) Anti-ulcer effect of tea catechin in rats. Biol. Pharm. Bull. 29: 2206-2213
9. Hansen, M. B. (2003) Neurohumoral control of gastrointestinal motility. Physiol. Res. 52: 1-30
10. Hirschowitz, B. I. (1983) Neural and hormonal control of gastric secretion. Am. Physiol. Soc. 127: 128-158
11. Kang, K. A., Lee, K. H., Zhang, R., Piao, M., Chae, S., Kim, K. N., Jeon, Y. J., Park, D. B., You, H. J., Kim, J. S., Hyun, J. W. (2006) Caffeic acid protects hydrogen peroxide induced cell damage in wi-38 human lung fibroblast cells. Biol. Pharm. Bull. 29: 1820-1824
12. Kardošová, A., Ebringerová, A., Alföldi, J., Nosál'ová, G., Franová, S., Hríbalová, V. (2003) A biologically active fructan from the roots of Arctium lappa L., var. Herkules. Int. J. Biol. Macromol. 33: 135-140
13. Kitamura, K., Honda, M., Yoshizaki, H., Yamamoto, S., Nakane, H., Fukushima, M., Ono, K., Tokunaga, T. (1998) Baicalin, an inhibitor of HIV-1 production in vitro. Antiviral Res. 37: 131-140
14. Kobayashi, T., Ohta, Y., Yoshino, J., Nakazawa, S. (2001) Teprenone promotes the healing of acetic acid-induced chronic gastric ulcers in rats by inhibiting neutrophil infiltration and lipid peroxidation in ulcerated gastric tissues. Pharmacol. Res. 43: 23-30
15. Konturek, S. J., Konturek, P. C., Brzozowski, T., Konturek, J. W., Pawlik, W. W. (2005) From nerves and hormones to bacteria in the stomach; Nobel prize for achievements in gastrology during last century. J. Physiol. Pharmacol. 56: 507-530
16. +-adenosine triphosphatase in rats. Scand. J. Gastroenterol. 30: 944-951
17. Leonard, S. S., Keil, D., Mehlman, T., Proper, S., Shi, X., Harris, G. K. (2006) Essiac tea: scavenging of reactive oxygen species and effects on DNA damage. J. Ethnopharmacol. 103: 288-296
18. Lin, S.C., Chung, T. C., Lin, C. C., Ueng, T. H., Lin, Y. H., Lin, S. Y., Wang, L. Y. (2000) Hepatoprotective effects of Arctium lappa on carbon tetrachloride- and acetaminophen-induced liver damage. Am. J. Chin. Med. 28: 163-173
19. Lin, S. C., Lin, C. H., Lin, C. C., Lin, Y. H., Chen, C. F., Chen, I. C., Wang, L. Y. (2002) Hepatoprotective effects of Arctium lappa Linne on liver injuries induced by chronic ethanol consumption and potentiated by carbon tetrachloride. J. Biomed. Sci. 9: 401-409
20. Mahakunakorn, P., Tohda, M., Murakami, Y., Matsumoto, K., Watanabe, H. (2004) Antioxidant and free radical-scavenging activity of choto-san and its related constituents. Biol. Pharm. Bull. 27: 38-46
21. +-ATPase and acid secretion by cassigarol A: a polyphenol from Cassia garrettiana Craib. Biochem. Pharmacol. 44: 33-37
22. Pereira, J. V., Bergamo, D. C. B., Pereira, J. O., França, S. C., Pietro, R., Sousa, Y. T. C. S. (2005) Antimicrobial activity of Arctium lappa constituents against microorganisms commonly found in endodontic infections. Braz. Dent. J. 16: 192-196
23. Repetto, M. G., Llesuy, S. F. (2002) Antioxidant properties of natural compounds used in popular medicine for gastric ulcers. Braz. J. Med. Biol. Res. 35: 523-534
24. Robert, A., Nezamis, J. E., Lancaster, C., Hauchar, A. J. (1979) Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl and thermal injury. Gastroenterology 77: 433-443
25. Rodriguez, J. A., Astudillo, L., Schmeda-Hirschmann, G. (2003) Oleanolic acid promotes healing of acetic acid-induced chronic gastric lesions in rats. Pharmacol. Res. 48: 291-294
26. Sagar, L., Sehgal, R., Ojha, S. (2005) Evaluation of antimotility effect of Lantana camara L. var. acuelata constituents on neostigmine induced gastrointestinal transit in mice. BMC Complement. Altem. Med. 5: 18
27. Sbolli, K. C. (2003) Arctium lappa: Efeitos depressores do sistema nervoso central em roedores. Curitiba. Dissertação (Mestrado em Farmacologia) - Setor de Ciências Biológicas, Universidade Federal do Paraná
28. Schröder, H. C., Merz, H., Steffen, R., Muller, W. E., Sarin, P. S., Trum, M. S., Schulz, J., Eich, E. (1990) Differential in vitro anti-HIV activity of natural lignans. Z. Naturforsch. 45: 1215-1221
29. Shay, H., Komarov, S. A., Fels, S. S., Meranze, D., Gruenstein, M., Siplet, H. (1945) A simple method for the uniform production of gastric ulceration in rat. Gastroenterology 5: 43-61
30. Shi, G. R., Rao, L. Q., Yu, H. Z. (2007) Yeast-cell-based microencapsulation of chlorogenic acid as a water-soluble antioxidant. J. Food Engineer. 80: 1060-1067
31. Soliman, K. F., Mazzio, E. A. (1998) In vitro attenuation of nitric oxide production in C6 astrocyte cell culture by various dietary compounds. Proc. Soc. Exp. Biol. Med. 218: 390-397
32. Suchitra, A. D., Dkhar, S. A., Shewade. D.G., Shashindran, C. H. (2003) Relative efficacy of some prokinetic drugs in morphine-induced gastrointestinal transit delay in mice. World J Gastroenterol. 9: 779-783
33. Takagi, E., Okabe, S., Saziki, R. (1969) A new method for the production of chronic gastric ulcer in rats and the effect of several drugs on healing. Jpn J. Pharmacol. 19: 416-426
34. Wallace, J. L. (2005) Recent advances in gastric ulcer therapeutics. Curr Opin Pharmacol. 5: 573-577
35. Wallace, J. L., Ma, L. (2001) Inflammatory mediators in gastrointestinal defense injury. Exp. Biol. Med. 226: 1003-1015
36. Wang, Q., Wang, Y. T., Pu, S. P, Zheng, Y. T. (2004) Zinc coupling potentiates anti-HIV-1 activity of baicalin. Biochem. Biophys. Res. Commun. 324: 605-610
37. Wang, B. S., Yen, G. C., Chang, L. W., Yen, W. J., Duh, P. D. (2006) Protective effects of burdock (Arctium lappa Linne) on oxidation of low-density lipoprotein and oxidative stress in RAW 264.7 macrophages. Food Chem. 101: 729-738