Nonribosomal peptide synthetase in responsible for the biosynthesis of siderophore in Vibrio vulnificus MO6-24/O

Journal of Microbiology and Biotechnology

Volumn 18, Issue 1, 2008, Pages 35-42

  Kim, In Hwang ^a   Shim, Jung Im ^a   Lee, Ko Eun ^a   Hwang, Won ^a   Kim, Ik Jung ^a   Choi, Sang Ho ^b   Kim, Kun Soo ^a  

^a Sogang University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Nonribosomal peptide synthase; Siderophore; Vibrio vulnificus

Indexed keywords

BACTERIAL PROTEIN; FERRIC UPTAKE REGULATOR; PEPTIDE SYNTHASE; SIDEROPHORE; VIBRIO VULNIFICUS SIDEROPHORE SYNTHASE A; VIBRIO VULNIFICUS SIDEROPHORE SYNTHASE B; IRON; NON RIBOSOMAL PEPTIDE SYNTHASE; NON-RIBOSOMAL PEPTIDE SYNTHASE;

ARTICLE; BACTERIAL VIRULENCE; BIOSYNTHESIS; CONTROLLED STUDY; DNA FLANKING REGION; GENE EXPRESSION; GENE IDENTIFICATION; GENE INSERTION; GENETIC ASSOCIATION; GENETIC SCREENING; MOLECULAR CLONING; NONHUMAN; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; VIBRIO VULNIFICUS; ANIMAL; CHEMISTRY; COSMID; CULTURE MEDIUM; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; GRAM NEGATIVE INFECTION; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MORTALITY; MOUSE; NUCLEOTIDE SEQUENCE; PATHOGENICITY; TRANSPOSON; VIRULENCE;

MUS; VIBRIO VULNIFICUS;

ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; CLONING, MOLECULAR; COSMIDS; CULTURE MEDIA; DNA TRANSPOSABLE ELEMENTS; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; IRON; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PEPTIDE SYNTHASES; SIDEROPHORES; VIBRIO INFECTIONS; VIBRIO VULNIFICUS; VIRULENCE;

EID: 43749089410     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Aisen, P., A. Leibman, and C. L. Sia. 1972. Molecular weight and subunit structure of hagfish transferrin. Biochemistry 11: 3461-3464.
2. Biosca, E. G., B. Fouz, E. Alcaide, and C. Amaro. 1996. Siderophore-mediated iron acquisition mechanisms in Vibrio vulnificus biotype 2. Appl. Environ. Microbiol. 62: 928-935.
3. Butterton, J. R., M. H. Choi, P. I. Watnick, P. A. Carroll, and S. B. Calderwood. 2000. Vibrio cholerae VibF is required for vibriobactin synthesis and is a member of the family of nonribosomal peptide synthases. J. Bacteriol. 182: 1731-1738.
4. Butterton, J. R., J. A. Stoebner, S. M. Payne, and S. B. Calderwood. 1992. Cloning, sequencing, and transcriptional regulation of viuA, the gene encoding the ferric vibriobactin receptor of Vibrio cholerae. J. Bacteriol. 174: 3729-3738.
5. Choi, H. K., N. Y. Park, D. Kim, H. J. Chung, S. Ryu, and S. H. Choi. 2002. Promoter analysis and regulatory characteristics of vvhBA encoding cytolytic hemolysin of Vibrio vulnificus. J. Biol. Chem. 277: 47292-47299.
6. Clark, V. L. and P. M. Bavoil. 1994. Bacterial pathogenesis. Methods Enzymol. 235: 313-372.
7. Crosa, J. H. 1997. Signal transduction and transcriptional and posttranscriptional control of iron-regulated genes in bacteria. Microbiol. Mol. Biol. Rev. 61: 319-336.
8. Crosa, J. H. and C. T. Walsh. 2002. Genetics and assembly line enzymology of siderophore biosynthesis in bacteria. Microbiol. Mol. Biol. Rev. 66: 223-249.
9. De Lorenzo, V., M. Herrero, U. Jakubzik, and K. N. Timmis. 1990. Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in Gram-negative eubacteria, J. Bacteriol. 172: 6568-6572.
10. Dessaux, Y., J. Tempe, and S. K. Farrand. 1987. Genetic analysis of mannityl opine catabolism in octopine-type Agrobacterium tumefaciens, strain 15955. Mol. Gen. Genet. 208: 301-308.
11. Escolar, L., J. Perez-Matin, and V. de Lorenzo. 1999. Opening the iron box: Transcriptional metalloregulation by the Fur protein. J. Bacteriol. 181: 6223-6229.
12. Griffiths, G. L., S. P. Sigel, S. M. Payne, and J. B. Neilands. 1984. Vibriobactin, a siderophore from Vibrio cholerae. J. Biol. Chem. 259: 383-385.
13. Herrero, M., V. de Lorenzo, and K. N. Timmis. 1990. Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in Gram-negative bacteria. J. Bacteriol. 172: 6557-6567.
14. Johnston, J. M., S. F. Becker. and L. M. McFarland. 1985. Vibrio vulnificus. Man and the sea. JAMA 253: 2850-2853.
15. Klebba, P. E., J. M. Rutz. J. Liu. and C. K. Murphy. 1993. Mechanisms ot TonB-catalyzed iron transport through the enteric bacterial cell envelop. J. Bioenerg. Biomembr. 25: 603-611.
16. Lankford, C. E. 1973. Bacterial assimilation of iron. Crit. Rev. Microbiol. 2: 273-331.
17. Lee, H. J., K. J. Park, A. Y. Lee, S. G. Park, B. C. Park, K. H. Lee, and S. J. Park. 2003. Regulation of fur expression by RpoS and fur in Vibrio vulnificus. J. Bacteriol. 185: 5891-5896.
18. Lee, J. H., J.-E. Rhee, U. Park, H.-M. Ju, B. C. Lee, T. S. Kim, H. S. Jeong, and S. H. Choi. 2007. Identification and functional analysis of Vibrio vulnificus SmcR, a novel global regulator. J. Microbiol. Biotechnol. 17: 325-334.
19. Lee, K.-E., J.-S. Bang, C.-H. Baek, D.-K. Park, W. Hwang, and K.-S. Kim. 2001. IVET-based identification of virulence factors in Vibrio vulnificus MO6-24/O. J. Microbiol. Biotechnol. 17: 234-243.
20. Lieu. H.-Y., H.-S. Song, S.-N. Yang, J.-H. Kim. H.-J. Kim, Y.-D. Park, C.-S. Park, and H.-Y. Kim. 2006. Identification of proteins affected by iron in Saccharomyces cerevisiae using proteome analysis J. Microbiol. Biotechnol. 16: 946-951.
21. Litwin, C. M., T. W. Rayback. and J. Skinner. 1996. Role of catechol siderophore synthesis in Vibrio vulnificus virulence. Infect. Immun. 64: 2834-2838.
22. Lorenzo, M. D., S. Popperlaars, M. Stork, Nagasawa, M. E. Tolmasky, and J. H. Crosa. 2004. A nonribosomal peptide synthase with a novel domain organization is essential for siderophore biosynthesis in Vibrio anguillarum. J. Bacteriol. 186: 7327-7336.
23. McIntosh, M. A., C. L. Pickett, S. S. Chenault, and C. F. Earhart. 1978. Suppression of iron uptake deficiency in Escherichia coli K-12 by loss of two major outer membrane proteins. Biochem. Biophys. Res. Commun. 51: 1106-1112.
24. Mekalanos. J. J. 1992. Environmental signals controlling expression of virulence determinants in bacteria. J. Bacteriol. 174: 1-7
25. O'Brien, I. G. and F. Gibson. 1970. The structure of enterochelin and related 2,3-dihydroxy-N-benzoylserine conjugates from Escherichia coli. Biochim. Biophys. Acta 215: 393-402.
26. Okujo, N., M. Saito, S. Yamamoto, T. Yoshida, S. Miyoshi, and S. Shinoda. 1994. Structure of vulnibactin, a new polyamine-containing siderophore from Vibrio vulnificus. Biomaterials 7: 109-116.
27. Panina, E. M., A. A, Mironov, and M. S. Gelfand, 2001. Comparative analysis of FUR regulons in gamma-proteobacteria. Nucleic Acids Res. 29: 5195-5206.
28. Reddy, G. P., U. Hayat, C. Abeygunwardana. C. Fox, A. C. Wright, D. R. Maneval Jr., C. A. Bush nnd J. G. Morris Jr. 1992. Purification and determination of the structure of capsular polysaccharide of Vibrio vulnificus MO6-24. J. Bacteriol. 174: 2620-2630.
29. Sambrook, J., E. F. Fritsh, and T. maniasis. 2001. Molecular Cloning: A Laboratory Manual, 3rd Ed. Cold Sping Harbor Laboratory Press, Cold Spring Harbor, N.Y.
30. Simpson, L. M. and J. D. Oliver. 1983. Siderophore production by Vibrio vulnificus. Infect. Immun. 41: 644-649.
31. Simon, R., U. Priefer, and A. Puhler. 1983. A broad host range mobilization system for in vivo genetic engineering: Transposon mutagenesis in Gram negative bacteria. Biol/Technology 1: 784-791.
32. Watnick, P. I., J. R. Butterton, and S. B. Calderwood, 1998. The interaction of the Vibrio cholerae transcription factors Fur and IrgB with the overlapping promoters of two virulence genes, irgA and irgB. Gene 209: 65-70.
33. Webster, A. C. and Litwin, C. M. 2000. Cloning and characterization of vuuA, a gene encoding the Vibrio vulnificus ferric vulnibactin receptor. Infect. Immun. 68; 526-534.
34. Weinberg, E. D. 1974. Iron and susceptibility to infectious disease. Science 184: 952-956.
35. Weinberg. E. D. 1978. Iron and infection. Microbiol. Rev. 42: 45-66.
36. Wright, A. C., L. M. Simpson, and J.D. Oliver. 1981. Role of iron in the pathogenesis of Vibrio vulnificus infections. Infect. Immun. 34: 503-507.
37. Wyckoff, E. E., J. A. Stoebner, and K. E. Reed. 1997. Cloning of a Vibrio cholerae vibriobactin gene cluster: Identification of genes required for early steps in siderophore biosynthesis. J. Bacteriol. 179: 7055-7962.