Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3

Journal of Biological Chemistry

Volumn 283, Issue 13, 2008, Pages 8711-8722

  Dorwart, Michael R ^a,b   Shcheynikov, Nikolay ^a   Baker, Jennifer M R ^c,d   Forman Kay, Julie D ^c,d   Muallem, Shmuel ^a   Thomas, Philip J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALS; PROBABILITY DENSITY FUNCTION;

BIO-CHEMICALS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; DO-MAINS; EXPRESSION SYSTEMS; FAMILY MEMBERS; FUNCTIONAL PROTEINS; GENETIC DISORDERS; ION TRANSPORTS; LIMITED PROTEOLYSES; MEMBRANE PROTEINS; MISFOLDING; MOLECULAR MECHANISMS; PLASMA MEMBRANES; SOLUTE CARRIERS; TRANSMEMBRANE;

CELL MEMBRANES;

CARRIER PROTEINS AND BINDING PROTEINS; SOLUTE CARRIER 26 FAMILY MEMBER 3 PROTEIN; SULFATE TRANSPORTER AND ANTI SIGMA FACTOR PROTEIN; UNCLASSIFIED DRUG; ANTIPORTER; CHLORIDE; SLC26A3 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONGENITAL CHLORIDE LOSING DIARRHEA; DIARRHEA; GENE MUTATION; GENETIC DISORDER; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; ION TRANSPORT; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN ISOLATION; ANIMAL; CELL LINE; CERCOPITHECUS; CHEMISTRY; CIRCULAR DICHROISM; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PROTEIN MOTIF; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; TEMPERATURE;

BACTERIA (MICROORGANISMS); MAMMALIA;

AMINO ACID MOTIFS; ANIMALS; ANTIPORTERS; CELL LINE; CERCOPITHECUS AETHIOPS; CHLORIDES; CIRCULAR DICHROISM; CONSERVED SEQUENCE; DIARRHEA; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; TEMPERATURE;

EID: 43749089149     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M704328200     Document Type: Article

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