Metabolon disruption: A mechanism that regulates bicarbonate transport

EMBO Journal

Volumn 24, Issue 14, 2005, Pages 2499-2511

  Alvarez, Bernardo V ^a   Vilas, Gonzalo L ^a   Casey, Joseph R ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Bicarbonate transport; Carbonic anhydrase; Cystic fibrosis; Protein kinase C; SLC26A6

Indexed keywords

ANGIOTENSIN; BICARBONATE; CARBON DIOXIDE; CARBONATE DEHYDRATASE; CARRIER PROTEIN; MULTIENZYME COMPLEX; PROTEIN KINASE C; PROTEIN SLC26A6; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYST; CELL MEMBRANE TRANSPORT; CHEMICAL MODIFICATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANGIOTENSIN II; BICARBONATES; BIOLOGICAL TRANSPORT, ACTIVE; CARBONIC ANHYDRASE II; CELL LINE; HUMANS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS; TRANSFECTION;

EID: 23044434059     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600736     Document Type: Article

References (48)

1. Alvarez BV, Fujinaga J, Casey JR (2001a) Molecular basis for angiotensin II-induced increase of chloride/bicarbonate exchange in the myocardium. Circ Res 89: 1246-1253
2. Alvarez BV, Kieller DM, Quon AL, Markovich D, Casey JR (2004) Slc26a6: a cardiac chloride-hydroxyl exchanger and predominant chloride-bicarbonate exchanger of the mouse heart. J Physiol 561: 721-734
3. Alvarez BV, Loiselle FB, Supuran CT, Schwartz GJ, Casey JR (2003) Direct extracellular interaction between carbonic anhydrase IV and the human NBC1 sodium/bicarbonate co-transporter. Biochemistry 42: 12321-12329
4. Alvarez L, Fanjul M, Carter N, Hollande E (2001b) Carbonic anhydrase II associated with plasma membrane in a human pancreatic duct cell line (CAPAN-1). J Histochem Cytochem 49: 1045-1053
5. Aravind L, Koonin EV (2000) The STAS domain-a link between anion transporters and antisigma-factor antagonists. Curr Biol 10: R53-R55
6. 2+-dependent anion secretion by protein kinase C in normal and cystic fibrosis pancreatic duct cells. Biochim Biophys Acta 1418: 31-38
7. Chernova MN, Jiang L, Friedman DJ, Darman RB, Lohi H, Kere J, Vandorpe DH, Alper SL (2005) Functional comparison of mouse slc26a6 anion exchanger with human SLC26A6 polypeptide variants: differences in anion selectivity, regulation, and electrogenicity. J Biol Chem 280: 8564-8580
8. Cousin JL, Motais R (1976) The role of carbonic anhydrase inhibitors on anion permeability into ox red blood cells. J Physiol 256: 61-80
9. - transport can be rescued by carbonic anhydrase II presented on an adjacent AE1 protomer. J Biol Chem 278: 44949-44958
10. Everett LA, Glaser B, Beck JC, Idol JR, Buchs A, Heyman M, Adawi F, Hazani E, Nassir E, Baxevanis AD, Sheffield VC, Green ED (1997) Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS). Nat Genet 17: 411-422
11. Everett LA, Green ED (1999) A family of mammalian anion transporters and their involvement in human genetic diseases. Hum Mol Genet 8: 1883-1891
12. Gross E, Pushkin A, Abuladze N, Fedotoff O, Kurtz I (2002) Regulation of the sodium bicarbonate cotransporter kNBC1 function: role of Asp (986), Asp (988) and kNBC1-carbonic anhydrase II binding. J Physiol 544: 679-685
13. Hastbacka J, Superti-Furga A, Wilcox WR, Rimoin DL, Cohn DH, Lander ES (1996) Atelosteogenesis type II is caused by mutations in the diastrophic dysplasia sulfate-transporter gene (DTDST): evidence for a phenotypic series involving three chondrodysplasias. Am J Hum Genet 58: 255-262
14. - secretion from guinea pig pancreatic ducts. Am J Physiol Cell Physiol 288: C1030-C1041
15. Khandoudi N, Albadine J, Robert P, Krief S, Berrebi-Bertrand I, Martin X, Bevensee MO, Boron WF, Bril A (2001) Inhibition of the cardiac electrogenic sodium bicarbonate cotransporter reduces ischemic injury. Cardiovasc Res 52: 387-396
16. Knauf F, Yang CL, Thomson RB, Mentone SA, Giebisch G, Aronson PS (2001) Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc Natl Acad Sci USA 98: 9425-9430
17. - transport in cystic fibrosis. EMBO J 21: 5662-5672
18. Ko SB, Zeng W, Dorwart MR, Luo X, Kim KH, Millen L, Goto H, Naruse S, Soyombo A, Thomas PJ, Muallem S (2004) Gating of CFTR by the STAS domain of SLC26 transporters. Nat Cell Biol 6: 343-350
19. Kovacs H, Comfort D, Lord M, Campbell ID, Yudkin MD (1998) Solution structure of SpoIIAA, a phosphorylatable component of the system that regulates transcription factor sigmaF of Bacillus subtilis. Proc Natl Acad Sci USA 95: 5067-5071
20. + exchanger. J Biol Chem 277: 36085-36091
21. Lohi H, Kujala M, Kerkela E, Saarialho-Kere U, Kestila M, Kere J (2000) Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger. Genomics 70: 102-112
22. Lohi H, Lamprecht G, Markovich D, Heil A, Kujala M, Seidler U, Kere J (2003) Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains. Am J Physiol Cell Physiol 284: C769-C779
23. - cotransporter by carbonic anhydrase II and PKA. Am J Physiol Cell Physiol 286: C1423-C1433
24. Mahieu I, Becq F, Wolfensberger T, Gola M, Carter N, Hollande E (1994) The expression of carbonic anhydrases II and IV in the human pancreatic cancer cell line (Capan 1) is associated with bicarbonate ion channels. Biol Cell 81: 131-141
25. Makela S, Kere J, Holmberg C, Hoglund P (2002) SLC26A3 mutations in congenital chloride diarrhea. Hum Mutat 20: 425-438
26. McMurtrie HL, Cleary HJ, Alvarez BV, Loiselle FB, Sterling D, Morgan PE, Johnson DE, Casey JR (2004) The bicarbonate transport metabolon. J Enzyme Inhib Med Chem 19: 231-236
27. Mount DB, Romero MF (2004) The SLC26 gene family of multifunctional anion exchangers. Pflugers Arch 447: 710-721
28. - exchanger PAT1 and gastric H-K-ATPase in stomach parietal cells. Am J Physiol Gastrointest Liver Physiol 283: G1207-G1216
29. Pushkin A, Abuladze N, Gross E, Newman D, Tatishchev S, Lee I, Fedotoff O, Bondar G, Azimov R, Ngyuen M, Kurtz I (2004) Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells. J Physiol 559: 55-65
30. Rossi A, Superti-Furga A (2001) Mutations in the diastrophic dysplasia sulfate transporter (DTDST) gene (SLC26A2): 22 novel mutations, mutation review, associated skeletal phenotypes, and diagnostic relevance. Hum Mutat 17: 159-171
31. Schwartz GJ (2002) Physiology and molecular biology of renal carbonic anhydrase. J Nephrol 15 (Suppl 5): S61-S74
32. - exchange in the villous epithelium of intact murine duodenum. Am J Physiol Gastrointest Liver Physiol 288: G1241-G1251
33. Spicer SS, Ge ZH, Tashian RE, Hazen-Martin DJ, Schulte BA (1990) Comparative distribution of carbonic anhydrase isozymes III and II in rodent tissues. Am J Anat 187: 55-64
34. Stanasila L, Perez JB, Vogel H, Cotecchia S (2003) Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization. J Biol Chem 278: 40239-40251
35. - exchanger binds carbonic anhydrase IV. J Biol Chem 277: 25239-25246
36. Sterling D, Brown NJ, Supuran CT, Casey JR (2002b) The functional and physical relationship between the DRA bicarbonate transporter and carbonic anhydrase II. Am J Physiol Cell Physiol 283: C1522-C1529
37. Sterling D, Casey JR (2002) Bicarbonate transport proteins. Biochem Cell Biol 80: 483-497
38. Sterling D, Reithmeier RA, Casey JR (2001) A transport metabolon. Functional interaction of carbonic anhydrase II and chloride/ bicarbonate exchangers. J Biol Chem 276: 47886-47894
39. Steward MC, Ishiguro H, Case RM (2005) Mechanisms of bicarbonate secretion in the pancreatic duct. Annu Rev Physiol 67: 377-409
40. Thomas WG, Thekkumkara TJ, Baker KM (1996) Cardiac effects of AII. AT1A receptor signaling, desensitization, and internalization. Adv Exp Med Biol 396: 59-69
41. Tsang SW, Cheng CH, Leung PS (2004) The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis. Regul Pept 119: 213-219
42. - anion exchanger binding site to the amino-terminal region of carbonic anhydrase II. Biochemistry 39: 13344-13349
43. - anion exchanger AE1. Biochemistry 39: 5527-5533
44. - exchanger. J Biol Chem 273: 28430-28437
45. Waldegger S, Moschen I, Ramirez A, Smith RJ, Ayadi H, Lang F, Kubisch C (2001) Cloning and characterization of SLC26A6, a novel member of the solute carrier 26 gene family. Genomics 72: 43-50
46. - exchanger in the small intestine. Am J Physiol Gastrointest Liver Physiol 282: G573-G579
47. Wang Z, Wang T, Petrovic S, Tuo B, Riederer B, Barone S, Lorenz JN, Seidler U, Aronson PS, Soleimani M (2005) Renal and intestinal transport defects in Slc26a6-null mice. Am J Physiol Cell Physiol 288: C957-C965
48. Xie Q, Welch R, Mercado A, Romero MF, Mount DB (2002) Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1. Am J Physiol Renal Physiol 283: F826-F838