In vitro hepatoprotective and antioxidant activities of diprenylated isoflavonoids from Erythrina senegalensis (Fabaceae)

Pharmacologyonline

Volumn 1, Issue , 2008, Pages 382-391

  Donfack, Jean Hubert ^a   Nico, Frederic Njayou ^a   Ngameni, Barthelemy ^a   Tchana, Angele ^a   Chuisseu, Pascal Djamen ^a   Finzi, Paola Vita ^b   Ngadjui, Bonaventure Tchaleu ^a   Moundipa, Paul Fewou ^a  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

Antihepatotoxic; Antioxidant; Erythrina senegalensis; Fabaceae; Hepatoprotective; Isoflavonoids

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,3 DIHYDRO 2' HYDROXYOSAJIN; 6,8 DIPRENYLGENISTEIN; ALCOHOL; ASCORBIC ACID; BETA CAROTENE; CARBON TETRACHLORIDE; ERYTHRINA EXTRACT; ERYTHRINA SENEGALENSIS EXTRACT; ISOFLAVONOID; LACTATE DEHYDROGENASE; LINOLEIC ACID; LIPID; OSAJIN; SILYMARIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BARK; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG STRUCTURE; ERYTHRINA; ERYTHRINA SENEGALENSIS; EXPERIMENTAL MODEL; HEPATITIS; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; IN VITRO STUDY; LEGUME; LIPID PEROXIDATION; LIVER PROTECTION; LIVER SLICE; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT STEM; PURIFICATION; RAT; THIN LAYER CHROMATOGRAPHY; TRADITIONAL MEDICINE; ULTRAVIOLET SPECTROSCOPY;

EID: 43649104246     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Malgras D. Arbres et arbustes guérisseurs des savanes Maliennes. Publié avec le concours du comité catholique contre la faim et pour le développernent. ACCT-KARTHALA. 1992: 285
2. Moundipa PF, Njayou F N, Yantitoum S, Sonke B and Tchouanguep FM. Medical plants used in Bamoun region of the western province of Cameroon against jaundice and other liver disorders. Cameroon Journal of Biological and Biochemical Sciences. 2002:12: 39-46.
3. Wandji, J, Tanee F Z, Tillequin F, Seguin E and Koch M. Two isoflavones from Erythrina senegalensis. Phytochemistry 1994:35:245-8.
4. Saidu K, OnahJ, Orisadipe A, Olusola A, Wambebe C and Gamaniel K, Antiplasmodial analgesic and anti-inflammatory activities of the aqueous extract of the stem bark of Erythrina senegalensis, Journal of Ethnopharmacology. 2000: 71: 275-280.
5. Shiao YJ, Wang CN, Wang WY and Lin YL Neuroprotective flavonoids from Flemingia macrophylla. Planta Medica. 2005: 71:835-840.
6. Bartosikova L, Necas J, Suchy V, Janostikova E, Bartosik T, Jurica J, Florian T, Klusakova J and Frydrych M. Protective effects of Osajin in ischemia-reperfusion of laboratory rat kidney. Pharmazie. 2006. 61: 552-5.
7. Florian T, Necas J, Bartosikova L, Klusakova J, Suchy V, El Naggar, El Moataz B, Janostikova, E and Bartosik T. Effects of prenylated isoflavones osajin and pomiferin in premedication on heart ischemia-reperfusion. Biomedical Papers. 2006: 150 Suppl:93-100.
8. Middleton MJR, Chithan K and Theoharis CT. The effect of plant flavonoid on mammalian cells: implications on inflammation, heart disease and cancer. Pharmacol. Rev. 2000: 52: 673-751.
9. Wormser U. and Zakine B.S. The liver slices system: An in vitro acute toxicity for assessment of hepatotoxins and their antidotes. Toxicology in vitro. 1990: 4: 449-451
10. Brand Williams W, Cuvelier ME and Berset C. Use of free radical method to evaluate antioxidant activity. Lebensm Wiss Technol. 1995: 28: 25-30.
11. Miller HE A simplified method for the evaluation of anti-oxidant. J. Am. Oil. Chem. Soc. 1971: 48-91.
12. Benzie I and Strain J J. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay. Analytical Biochemistry. 1996: 239: 70-6.
13. Garle M J and Fry J R. Detection of reactive metabolites in vitro, Toxicology. 1989: 54: 101-110.
14. Ulf A.N, Lars-Inge O, Gunnar C and Ann Christin B. Inhibition of lipid peroxidation by spin labels. The Journal of Biological Chemistry. 1989: 264:11131-5.
15. Wills EO. Evaluation of lipid peroxidation and biological membranes. In: K. Snell and B. Mullock. Biochemical Toxicology. A practical approach. IRL Press Oxford. 1987:127-151.
16. Singhal AK., Sharma R P, Thyagarajan G, Herz W, Govindan S V: New prenylated isoflavones and a prenylate dihydroflavonol from Millettia pachycarpa. Phytochemistry 1980:19:929-934
17. Oh WK, Lee H S, Ahn S C, Ahn J S, Mbafor JT, Wandji J, Fomum Z T, Chang H K, Kim Y H. Prenylated isoflafonoids from Erythrina senegalensis. Phytochemistry 1999:51: 1147-1150
18. Delle Monache G, Scurria R, Vitali A, Botta B, Monacelli B, Pasqua G, Palocci C, Cernia E. Two isoflavones and one flavone from the fruits of Madura pomifera. Phytochemistry. 1994:37: 893-898.
19. Warburg O. Versuche an überlebendem Karzinomgewebe. Biochem. Z. 1923: 142: 317-333.
20. Lerche-Langrand C and Toutain HJ. Precision cut liver slices: characteristic and use for in vitro pharmaco-toxicology. Toxicology. 2000:153:221-253
21. Moronvalle-Halley V, Sacré-Salem B, Sallez V, Labbe G and Gautier JC. Toxicology 2005:207: 203-214.
22. Onderwater RC, Commandeur JN and Vermeulen NP. Comparative citotoxicity of N-substituted N'-(4-imidazol-ethyl)thiourea in precision-cut rat liver slioes. Toxicolog. 2004:197: 81-91.
23. Recknagel RO and Glende EA. A new direction in the study of carbon tetrachloride, Hepatotoxicity Life Sci. 1973:33: 401-8.
24. Comporti M. Lipid peroxidation and cellular damage in toxic liver injury. Lab. Invest. 1985: 53: 599-623.
25. Gonzalez R, Anchota O, Pascual C, Pallon R, Frutos N aud Milian V. Hepatoprotective properties of lobenzarit in the rat. Biotechnol. Appl. 1991: 8: 140-7.
26. Martinez-Calva A, Campos Apalz E, Rosales-Vega A and Mourelle M. Vitamin E improves membrane lipid alterations induced by CC14 intoxication. J. Appl. Toxycol. 1984:10: 275-9.
27. Muriel P and Murelle M. Prevention by silymarin of membrane alterations in acute CC14 liver damage. J. Appl. Toxicol. 1990: 10: 275-9.
28. Gonzalez R, Corcho R, Reminez D, Rodriguez S, Anchota O, Merino A and Pascual C. Hepatoprotective effects of Propolis extract on Carbon Tetrachloride- induced liver injury in rats. Phytotherapy Research. 1995:9: 114-7.
29. Pascual C, Gonzalez R and Romay C. Drug effects on superoxide generation and chemiluminescence response of human leukocytes. Agents Actions. 1991:32:277-282.
30. Aniya y and Myagmar BE. Free radical scavenging action of medical herbs from Mongolia. Phytomedicine. 2000:7:221-9.
31. Gardner PT, Whites TAC, Mcphail D Band Duthie G D. The relative contribution of vitamin C, carotenoids and phenolics to the antioxidant potential of fruit juices. Food chem. 2000: 68: 471-4.
32. Czinneka E, Hagymasib K, Blazovisb A, Szkea E and Lemberkovics E. The in vitro effect of Helichrysi flos on microsomal lipid peroxidation. Ethnopharmacol. 2001: 77: 31-5.
33. Gil MI, Thomas-Barberan FA, Heiss-Pierce B and Kader A A. Antioxidant capacities, phenolic compounds, carotenoids and vitamin C contents of nectarine, peach and plums cultivars from California. J. Agric. Food Chem. 2002:50: 4976-82.
34. Tsao R, Sockovie E, Zhou T and Dale A. Antioxidant phytochemicals in Cultivated and Will Canadian Strawberries, Acta Horticulturae. 2003: 626: 25-36.