Identification of candidate cooperative genes of the Apc mutation in transformation of the colon epithelial cell by retroviral insertional mutagenesis

Cancer Science

Volumn 99, Issue 5, 2008, Pages 979-985

  Tanaka, Miwa ^a   Jin, Guang ^a   Yamazaki, Yukari ^a   Takahara, Tomoko ^a   Takuwa, Miki ^a   Nakamura, Takuro ^a  

^a CANCER INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; DYNEIN AXONEMAL HEAVY CHAIN 3; GENE PRODUCT; GENOMIC DNA; PROTEIN AHNAK; RNA BINDING MOTIF PROTEIN 9; SERINE THREONINE KINASE 17B; AHNAK PROTEIN, MOUSE; DNAH3 PROTEIN, MOUSE; DYNEIN ADENOSINE TRIPHOSPHATASE; MEMBRANE PROTEIN; TUMOR PROTEIN;

ANIMAL CELL; ARTICLE; COLON CANCER; COLON CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; CYTOSKELETON; EPITHELIUM CELL; GENE MUTATION; GENE OVEREXPRESSION; GENETIC IDENTIFICATION; MICROTUBULE; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RETROVIRUS INFECTION; UPREGULATION; VIRUS CELL TRANSFORMATION; ANIMAL; CELL LINE; CELL TRANSFORMATION; COLON; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PATHOLOGY; RETROVIRUS; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; COLON; DYNEIN ATPASE; EPITHELIAL CELLS; GENES, APC; MEMBRANE PROTEINS; MICE; MICROTUBULES; MUTAGENESIS, INSERTIONAL; MUTATION; NEOPLASM PROTEINS; RETROVIRIDAE; UP-REGULATION;

EID: 43649096022     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00757.x     Document Type: Article

References (37)

1. Malumbres M, Barbacid M. To cycle or not to cycle: A critical decision in cancer. Nat Rev Cancer 2001; 1: 222-31.
2. Jonkers J, Berns A. Retroviral insertional mutagenesis as a strategy to identify cancer genes. Biochem Biophys Acta 1996; 1287: 29-57.
3. Mikkers H, Berns A. Retroviral insertional mutagenesis: Tagging cancer pathways. Adv Cancer Res 2003; 88: 53-99.
4. Nakamura T. Retroviral insertional mutagenesis identifies oncogene cooperation. Cancer Sci 2005; 96: 7-12.
5. Jin G, Yamazaki Y, Takuwa M et al. Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis. Blood 2007; 109: 3998-4005.
6. Iwasaki M, Kuwata T, Yamazaki Y et al. Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood 2005; 105: 784-93.
7. Peters G, Lee AE, Dickson C. Activation of cellular gene by mouse mammary tumour virus may occur early in mammary tumor development. Nature 1984; 309: 273-5.
8. Johansson FK, Brodd J, Eklof C et al. Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging. Proc Natl Acad Sci USA 2004; 101: 11334-7.
9. Powell SM, Zilz N, Beazer-Barclay Y et al. APC mutations occur early during colorectal tumorigenesis. Nature 1992; 359: 235-7.
10. Fodde R, Smits R, Clevers H. Apc, signal transduction and genetic instability in colorectal cancer. Nat Rev Cancer 2001; 1: 55-67.
11. Min/+ mouse. Cancer Sci 2007; 98: 6-10.
12. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-67.
13. Morin PJ, Sparks AB, Korinek V et al. Activation of β-catenin-Tcf signaling in colon cancer by mutagen in β-catenin or APC. Science 1997; 275: 1787-90.
14. Whitehead RH, Joseph JL. Derivation of conditionally immortalized cell lines containing the Min mutation from the normal colonic mucosa and other tissues of an 'immortomouse'/Min hybrid. Epith Cell Biol 1994; 3: 119-25.
15. D'abaco GM, Whitehead RH, Burgess AW. Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas. Mol Cell Biol 1996; 16: 884-91.
16. b-tsA58 transgenic mouse. Proc Natl Acad Sci USA 1991; 88: 5096-100.
17. b-tsA58 transgenic mice. Proc Natl Acad Sci USA 1993; 90: 587-91.
18. Moser AR, Pitot HC, Dove WF. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990; 247: 322-4.
19. Su LK, Kinzler KW, Vogelstein B et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the Apc gene. Science 1992; 256: 668-70.
20. Gee MA, Heuser JE, Vallee RB. An extended microtubule-binding structure within the dynein motor domain. Nature 1997; 390: 636-9.
21. Koonce MP. Identification of a microtubule-binding domain in a cytoplasmic dynein heavy chain. J Biol Chem 1997; 272: 19714-18.
22. Ichii S, Takeda S, Horii A et al. Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP). Oncogene 1993; 8: 2399-405.
23. Levy DB, Smith KJ, Beazer-Barclay Y, Hamilton SR, Vogelstein B, Kinzler KW. Inactivation of both APC alleles in human and mouse tumors. Cancer Res 1994; 54: 5953-8.
24. + hematopoietic cells. Blood 2007; 110: 1770-8.
25. Husoy T, Cruciani V, Knutsen HK, Mikalsen SO, Olstorn HB, Alexander J. Cells heterozygous for the Apc Min mutation have decreased gap junctional intercellular communication and connexin43 level, and reduced microtubule polymerization. Carcinogenesis 2003; 24: 643-50.
26. Nakamura M, Zhou ZX, Lu KP. Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization. Curr Biol 2001; 11: 1062-7.
27. Milisav I. Dynein and dynein-related genes. Cell Motil Cytoskeleton 1998; 39: 261-72.
28. Ross JL, Wallace K, Shuman H, Goldman YE, Holzbaur E. Processive bidirectional motion of dynein-dynactin complexes in vitro. Nat Cell Biol 2006; 8: 562-70.
29. Vallee RB, Sheetz MP. Targeting of motor proteins. Science 1996; 271: 1539-44.
30. Hirokawa N. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 1998; 279: 519-26.
31. Vale RD. The molecular motor toolbox for intracellular transport. Cell 2003; 112: 467-80.
32. Komuro A, Masuda Y, Kobayashi K et al. The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells. Proc Natl Acad Sci USA 2004; 101: 4053-8.
33. Haase H, Pagel I, Khalina Y et al. The carboxyl-terminal ahnak domain induces actin bundling and stabilizes muscle contraction. FASEB J 2004; 18: 839-41.
34. Näthke I. Cytoskeleton out of the cupboard: Colon cancer and cytoskeletal changes induced by loss of APC. Nat Rev Cancer 2006; 6: 967-74.
35. Kiyosue MY, Tsukita S. Where is APC going? J Cell Biol 2001; 154: 1105-9.
36. Fearnhead NS, Britton MP, Bodmer WF. The ABC of APC. Human Mol Genet 2001; 10: 721-33.
37. Green RA, Wollman R, Kaplan KB. APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment. Mol Biol Cell 2005;16: 4609-22.