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Volumn 99, Issue 5, 2008, Pages 1063-1070

Downregulation of Tie2 gene by a novel antitumor sulfolipid, 3′-sulfoquinovosyl-1′-monoacylglycerol, targeting angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

3' SULFOQUINOVOSYL 1' MONOACYLGLYCEROL; ANGIOPOIETIN RECEPTOR; ANTINEOPLASTIC AGENT; VASCULOTROPIN; 1 MONO O ACYL 3 O (ALPHA D SULFOQUINOVOSYL) GLYCERIDE; 1-MONO-O-ACYL-3-O-(ALPHA-D-SULFOQUINOVOSYL)-GLYCERIDE; ANGIOGENESIS INHIBITOR; GLYCOLIPID; PROTEIN KINASE INHIBITOR;

EID: 43649085218     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00785.x     Document Type: Article
Times cited : (21)

References (42)
  • 1
    • 0025141337 scopus 로고
    • What is the evidence that tumor are angiogenesis dependent?
    • Folkman J. What is the evidence that tumor are angiogenesis dependent? J Natl Cancer Inst 1990; 82: 4-6.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 2
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005; 438: 932-6.
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 3
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly MS, Holmgren L, Shing Y et al. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994; 79: 315-28.
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3
  • 4
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly MS, Boehm T, Shing Y et al. Endostatin: An endogenous inhibitor of angiogenesis and tumor growth. Cell 1997; 88: 277-85.
    • (1997) Cell , vol.88 , pp. 277-285
    • O'Reilly, M.S.1    Boehm, T.2    Shing, Y.3
  • 5
    • 0032893263 scopus 로고    scopus 로고
    • SU5416 is a potentand selective inhibitor of vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
    • Fong TA, Shawver LK, Sun L et al. SU5416 is a potentand selective inhibitor of vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res 1999; 59: 99-106.
    • (1999) Cancer Res , vol.59 , pp. 99-106
    • Fong, T.A.1    Shawver, L.K.2    Sun, L.3
  • 6
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003; 9: 669-76.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 7
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Feherenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-42.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Feherenbacher, L.2    Novotny, W.3
  • 8
    • 13444278498 scopus 로고    scopus 로고
    • Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinicals studies
    • Gerber HP, Ferrara N. Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinicals studies. Cancer Res 2005; 65: 671-80.
    • (2005) Cancer Res , vol.65 , pp. 671-680
    • Gerber, H.P.1    Ferrara, N.2
  • 9
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature 2005; 438: 967-74.
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 10
    • 33344477298 scopus 로고    scopus 로고
    • Tie receptors and their angiopoietin ligands are context-depedent regulators of vascular remodeling
    • Eklund L, Olsen BR. Tie receptors and their angiopoietin ligands are context-depedent regulators of vascular remodeling. Exp Cell Res 2006; 312: 630-41.
    • (2006) Exp Cell Res , vol.312 , pp. 630-641
    • Eklund, L.1    Olsen, B.R.2
  • 11
    • 0030726988 scopus 로고    scopus 로고
    • Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie-2 in pathologic vascular growth
    • Lin P, Polverini P, Dewhirst M, Shan S, Roao PS, Peters KG. Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie-2 in pathologic vascular growth. J Clin Invest 1997; 100: 2072-8.
    • (1997) J Clin Invest , vol.100 , pp. 2072-2078
    • Lin, P.1    Polverini, P.2    Dewhirst, M.3    Shan, S.4    Roao, P.S.5    Peters, K.G.6
  • 12
    • 13144254247 scopus 로고    scopus 로고
    • Anti-angiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
    • Lin P, Buxton JA, Acheson A et al. Anti-angiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. Proc Natl Acad Sci USA 1998; 95: 8829-34.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8829-8834
    • Lin, P.1    Buxton, J.A.2    Acheson, A.3
  • 13
    • 0033168916 scopus 로고    scopus 로고
    • Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway
    • Siemeister G, Schirner M, Weindel K et al. Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway. Cancer Res 1999; 59: 3185-91.
    • (1999) Cancer Res , vol.59 , pp. 3185-3191
    • Siemeister, G.1    Schirner, M.2    Weindel, K.3
  • 14
    • 0035255001 scopus 로고    scopus 로고
    • Differential inhibition of tumor angiogenesis by Tie2 and vascular endothelial growth factor receptor-2 dominant-negative receptor mutants
    • Stratmann A, Acker T, Burger AM, Amann K, Risau W, Plate KH. Differential inhibition of tumor angiogenesis by Tie2 and vascular endothelial growth factor receptor-2 dominant-negative receptor mutants. Int J Cancer 2001; 91: 273-82.
    • (2001) Int J Cancer , vol.91 , pp. 273-282
    • Stratmann, A.1    Acker, T.2    Burger, A.M.3    Amann, K.4    Risau, W.5    Plate, K.H.6
  • 15
    • 0032714316 scopus 로고    scopus 로고
    • Angiopoietin-1 and its receptor Tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells
    • Hayes AJ, Huang WQ, Mallah J, Yang D, Lippman ME, Li LY. Angiopoietin-1 and its receptor Tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells. Microvasc Res 1999; 58: 224-37.
    • (1999) Microvasc Res , vol.58 , pp. 224-237
    • Hayes, A.J.1    Huang, W.Q.2    Mallah, J.3    Yang, D.4    Lippman, M.E.5    Li, L.Y.6
  • 16
    • 0037966956 scopus 로고    scopus 로고
    • Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin
    • White RR, Shan S, Rusconi CP et al. Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin. Proc Natl Acad Sci USA 2003; 100: 5028-33.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5028-5033
    • White, R.R.1    Shan, S.2    Rusconi, C.P.3
  • 17
    • 7244253411 scopus 로고    scopus 로고
    • Inhibition of Tie-2 signaling induces endothelial cell apoptosis, decreases Akt signaling, and induces endothelial cell expression of the endogenous anti-angiogenic molecule, thrombospondin-1
    • Niu Q, Perruzzi C, Voskas D, Lawler J, Dumont DJ, Benjamin LE. Inhibition of Tie-2 signaling induces endothelial cell apoptosis, decreases Akt signaling, and induces endothelial cell expression of the endogenous anti-angiogenic molecule, thrombospondin-1. Cancer Biol Ther 2004; 3: 402-5.
    • (2004) Cancer Biol Ther , vol.3 , pp. 402-405
    • Niu, Q.1    Perruzzi, C.2    Voskas, D.3    Lawler, J.4    Dumont, D.J.5    Benjamin, L.E.6
  • 18
    • 10944262091 scopus 로고    scopus 로고
    • A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor
    • Tournaire R, Simon M-P, le Noble F, Eichmann A, England P, Pouyssegur J. A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor. EMBO Rep 2004; 5: 1-6.
    • (2004) EMBO Rep , vol.5 , pp. 1-6
    • Tournaire, R.1    Simon, M.-P.2    le Noble, F.3    Eichmann, A.4    England, P.5    Pouyssegur, J.6
  • 19
    • 0031035303 scopus 로고    scopus 로고
    • In vivo anti-tumour effect of 3′-sulphonoquinovosyl 1′-monoacylglyceride isolated from sea urchin (Strongylocentrotus intermedius) intestine
    • Sahara H, Ishikawa M, Takahashi N et al. In vivo anti-tumour effect of 3′-sulphonoquinovosyl 1′-monoacylglyceride isolated from sea urchin (Strongylocentrotus intermedius) intestine. Br J Cancer 1997; 75: 324-32.
    • (1997) Br J Cancer , vol.75 , pp. 324-332
    • Sahara, H.1    Ishikawa, M.2    Takahashi, N.3
  • 20
    • 0036163091 scopus 로고    scopus 로고
    • Anti-tumor effect of chemically synthesized sulfolipids based on sea urchin's natural sulfonoquinovosylmonoacylglycerols
    • Sahara H, Hanashima S, Yamazaki T et al. Anti-tumor effect of chemically synthesized sulfolipids based on sea urchin's natural sulfonoquinovosylmonoacylglycerols. Jpn J Cancer Res 2002; 93: 85-92.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 85-92
    • Sahara, H.1    Hanashima, S.2    Yamazaki, T.3
  • 21
    • 33644503844 scopus 로고    scopus 로고
    • α-Sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis
    • Sakimoto I, Ohta K, Yamazaki T et al. α-Sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis. Cancer Res 2006; 66: 2287-95.
    • (2006) Cancer Res , vol.66 , pp. 2287-2295
    • Sakimoto, I.1    Ohta, K.2    Yamazaki, T.3
  • 22
    • 0029065998 scopus 로고
    • Structure and expression of a smooth muscle cell-specific gene, SM22α
    • Solway J, Seltzer J, Samaha FF et al. Structure and expression of a smooth muscle cell-specific gene, SM22α. J Biol Chem 1995; 270: 13.460-9.
    • (1995) J Biol Chem , vol.270
    • Solway, J.1    Seltzer, J.2    Samaha, F.F.3
  • 23
    • 0038745370 scopus 로고    scopus 로고
    • Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer
    • Zhang L, Yang N, Park J et al. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res 2003; 63: 3403-12.
    • (2003) Cancer Res , vol.63 , pp. 3403-3412
    • Zhang, L.1    Yang, N.2    Park, J.3
  • 24
    • 0033566690 scopus 로고    scopus 로고
    • Potent antitumor activity of MS-247, a novel DNA minor grove binder, evaluated by an in.vitro and in vivo human cancer cell line panel
    • Yamori T, Matsunaga A, Sato S et al. Potent antitumor activity of MS-247, a novel DNA minor grove binder, evaluated by an in.vitro and in vivo human cancer cell line panel. Cancer Res 1999; 59: 4042-9.
    • (1999) Cancer Res , vol.59 , pp. 4042-4049
    • Yamori, T.1    Matsunaga, A.2    Sato, S.3
  • 25
    • 0036168343 scopus 로고    scopus 로고
    • An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines
    • Dan S, Tsunoda T, Kitahara O et al. An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines. Cancer Res 2002; 62: 1139-47.
    • (2002) Cancer Res , vol.62 , pp. 1139-1147
    • Dan, S.1    Tsunoda, T.2    Kitahara, O.3
  • 26
    • 0026695259 scopus 로고
    • Tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in the endothelial cells and their presumptive precursors
    • Dumont DJ, Yamaguchi TP, Conlon RA, Rossant J, Breitman ML. Tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in the endothelial cells and their presumptive precursors. Oncogene 1992; 7: 1471-80.
    • (1992) Oncogene , vol.7 , pp. 1471-1480
    • Dumont, D.J.1    Yamaguchi, T.P.2    Conlon, R.A.3    Rossant, J.4    Breitman, M.L.5
  • 27
    • 0027191251 scopus 로고
    • The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors
    • Dumont DJ, Gradwohl GJ, Fong GH, Auerbach R, Breitman ML. The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors. Oncogene 1993; 8: 1293-301.
    • (1993) Oncogene , vol.8 , pp. 1293-1301
    • Dumont, D.J.1    Gradwohl, G.J.2    Fong, G.H.3    Auerbach, R.4    Breitman, M.L.5
  • 28
    • 0028122465 scopus 로고
    • Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
    • Dumont DJ, Gradwohl G, Fong GH et al. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev 1994; 8: 1897-909.
    • (1994) Genes Dev , vol.8 , pp. 1897-1909
    • Dumont, D.J.1    Gradwohl, G.2    Fong, G.H.3
  • 29
    • 0029001244 scopus 로고
    • Distinct roles of the receptor tyrosine kinases Tie1 and Tie-2 in blood vessel formation
    • Sato TN, Tozawa Y, Deutsch U et al. Distinct roles of the receptor tyrosine kinases Tie1 and Tie-2 in blood vessel formation. Nature 1995; 376: 70-4.
    • (1995) Nature , vol.376 , pp. 70-74
    • Sato, T.N.1    Tozawa, Y.2    Deutsch, U.3
  • 30
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
    • Maisonpierre PC, Suri C, Jones PF et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science1997; 277: 55-60.
    • (1997) Science , vol.277 , pp. 55-60
    • Maisonpierre, P.C.1    Suri, C.2    Jones, P.F.3
  • 31
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan D. Signaling vascular morphogenesis and maintenance. Science 1997; 277: 48-50.
    • (1997) Science , vol.277 , pp. 48-50
    • Hanahan, D.1
  • 32
    • 0032890359 scopus 로고    scopus 로고
    • The angiopoietins: Ying and yang in angiogenesis
    • Davis S, Yancopoulos GD. The angiopoietins: Ying and yang in angiogenesis. Curr Top Microbiol Immunol 1999; 237: 173-85.
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 173-185
    • Davis, S.1    Yancopoulos, G.D.2
  • 33
    • 31544456613 scopus 로고    scopus 로고
    • Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoitic cell survival
    • Hamaguchi I, Morisada T, Azuma M et al. Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoitic cell survival. Blood 2006; 107: 1207-13.
    • (2006) Blood , vol.107 , pp. 1207-1213
    • Hamaguchi, I.1    Morisada, T.2    Azuma, M.3
  • 35
    • 0032541165 scopus 로고    scopus 로고
    • Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2
    • Witzenbichler B, Maisonpierre PC, Jones P, Yancopoulos GD, Isner JM. Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2. J Biol Chem 1998; 273: 18.514-21.
    • (1998) J Biol Chem , vol.273
    • Witzenbichler, B.1    Maisonpierre, P.C.2    Jones, P.3    Yancopoulos, G.D.4    Isner, J.M.5
  • 37
    • 0342657703 scopus 로고    scopus 로고
    • Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion
    • Kim I, Kim HG, Moon SO et al. Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion. Circ Res 2000; 86: 952-9.
    • (2000) Circ Res , vol.86 , pp. 952-959
    • Kim, I.1    Kim, H.G.2    Moon, S.O.3
  • 38
    • 0006677050 scopus 로고    scopus 로고
    • Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3V-kinase/Akt signal transduction pathway
    • Kim I, Kim HG, So JN, Kim JH, Kwak HJ, Koh GY. Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3V-kinase/Akt signal transduction pathway. Circ Res 2000; 86: 24-9.
    • (2000) Circ Res , vol.86 , pp. 24-29
    • Kim, I.1    Kim, H.G.2    So, J.N.3    Kim, J.H.4    Kwak, H.J.5    Koh, G.Y.6
  • 39
    • 2442608732 scopus 로고    scopus 로고
    • Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1)
    • Daly C, Wong V, Burova E et al. Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1). Genes Dev 2004; 18: 1060-71.
    • (2004) Genes Dev , vol.18 , pp. 1060-1071
    • Daly, C.1    Wong, V.2    Burova, E.3
  • 40
    • 0030460424 scopus 로고    scopus 로고
    • Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
    • Davis S, Aldrich TH, Jones PF et al. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 1996; 87: 1161-9.
    • (1996) Cell , vol.87 , pp. 1161-1169
    • Davis, S.1    Aldrich, T.H.2    Jones, P.F.3
  • 41
    • 0036112626 scopus 로고    scopus 로고
    • Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth
    • Hawighorst T, Skobe M, Streit M et al. Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth. Am J Pathol 2002; 160: 1381-92.
    • (2002) Am J Pathol , vol.160 , pp. 1381-1392
    • Hawighorst, T.1    Skobe, M.2    Streit, M.3
  • 42
    • 0038407310 scopus 로고    scopus 로고
    • Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors
    • Stoeltzing O, Ahmad SA, Liu W et al. Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors. Cancer Res 2003; 63: 3370-7.
    • (2003) Cancer Res , vol.63 , pp. 3370-3377
    • Stoeltzing, O.1    Ahmad, S.A.2    Liu, W.3


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