Protective effect of serofendic acid on ischemic injury induced by occlusion of the middle cerebral artery in rats

European Journal of Pharmacology

Volumn 586, Issue 1-3, 2008, Pages 151-155

  Nakamura, Tomohiro ^a   Kume, Toshiaki ^a   Katsuki, Hiroshi ^a   Niidome, Tetsuhiro ^a   Sugimoto, Hachiro ^a   Akaike, Akinori ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Free radical scavenger; Middle cerebral artery occlusion; Serofendic acid

Indexed keywords

NEUROPROTECTIVE AGENT; NORPHENAZONE; SCAVENGER; SEROFENDIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY OCCLUSION; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; MALE; NERVE DEGENERATION; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SCORING SYSTEM;

ANIMALS; ANTIPYRINE; BODY WEIGHT; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MIDDLE CEREBRAL ARTERY; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 43549102168     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.02.079     Document Type: Article

References (34)

1. Amemiya S., Kamiya T., Nito C., Inaba T., Kato K., Ueda M., Shimazaki K., and Katayama Y. Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats. Eur. J. Pharmacol. 516 (2005) 125-130
2. Akaike A., Katsuki H., and Kume T. Pharmacological and physiological properties of serofendic acid, a novel neuroprotective substance isolated from fetal calf serum. Life Sci. 74 (2003) 263-269
3. Andrabi S.A., Sayeed I., Siemen D., Wolf G., and Horn T.F. Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin. FASEB J. 18 (2004) 869-871
4. Appendino G., Belloro E., tron G.C., Jakupovic J., and Ballero M. Polycyclic diterpenoids from Euphorbia characias. Fitoterapia 71 (2000) 134-142
5. Charriaut-Marlangue C., Marhaill I., Represa A., Popovici T., Plotkine M., and Ben-Ari Y. Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis. J. Cereb. Blood Flow Metab. 16 (1996) 186-194
6. Charriaut-Marlangue C., Aggoun-Zouaoui D., Represa A., and Ben-Ari Y. Apoptotic features of selective neuronal death in ischemia, epilepsy and gp 120 toxicity. Trends Neurosci. 19 (1996) 109-114
7. Clemens J.A. Cerebral ischemia: gene activation, neuronal injury, and the protective role of antioxidants. Free Radic. Biol. Med. 28 (2000) 1526-1531
8. Coyle J.T., and Puttafarcken P. Oxidative stress, glutamate, and neurogenerative disorders. Science 262 (1993) 689-695
9. Culmsee C., Zhu C., Landshamer S., Becattini B., Wagner E., Pellecchia M., Blomgren K., and Plesnila N. Apoptosis-inducing factor triggered by poly (ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia. J. Neurosci. 25 (2005) 10262-10272
10. Dirnagl U., Ladecola C., and Moskowitz M.A. Pathobiology of ischemic stroke: an integrated view. Trends Neurosci. 22 (1999) 391-397
11. Fiskum G., Rosenthal R.E., Vereczki V., Martin E., Hoffman G.E., Chinopoulos C., and Kowaltowski A. Protection against ischemic brain injury by inhibition of mitochondrial oxidative stress. J. Bioenerg. Biomembr. 36 (2004) 347-352
12. Fujimura M., Tominaga T., and Chan P.H. Neuroprotective effect of an antioxidant in ischemic brain injury: involvement of neuronal apoptosis. Neurocrit. Care 2 (2005) 59-66
13. Kume T., Asai N., Nishikawa H., Mano N., Terauchi T., Taguchi R., Shirakawa H., Osakada F., Mori H., Asakawa N., Yonaga M., Nishizawa Y., Sugimoto H., Shimohama S., Katsuki H., Kaneko S., and Akaike A. Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 3288-3293
14. Kume T., Kawai Y., Yoshida K., Nakamizo T., Kanki R., Sawada H., Katsuki H., Shimohama S., Sugimoto H., and Akaike A. Protective effect of serofendic acid on glutamate-induced neurotoxicity in rat cultured motor neurons. Neurosci. Lett. 383 (2005) 199-202
15. Kume T., Taguchi R., Katsuki H., Akao M., Sugimoto H., Kaneko S., and Akaike A. Serofendic acid, a neuroprotective substance derived from fetal calf serum, inhibits mitochondrial membrane depolarization and caspase-3 activation. Eur. J. Pharmacol. 542 (2006) 69-76
16. Kuroda S., and Siesjo B.K. Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows. Clin. Neurosci. 4 (1997) 199-212
17. MacManus J.P., and Linnik M.D. Gene expression induced by cerebral ischemia. An apoptotic perspective. J. Cereb. Blood Flow Metab. 17 (1997) 815-832
18. Mizuno A., Imemura K., and Nakashima M. Inhibitory effect of MCI 186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion. Gen. Pharmacol. 30 (1998) 575-578
19. Morimoto T., Globus M.Y., Busto R., Martinez E., and Ginsberg M.D. Simultaneous measurement of salicylate hydroxylation and glutamate release in the penumbral cortex following transient middle cerebral artery occlusion in rats. J. Cereb. Blood Flow Metab. 16 (1996) 92-99
20. Murakami K., Kondo T., Kawase M., Li Y., Sato S., Sylvia F., Chen S.F., and Chan P.H. Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency. J. Neurosci. 18 (1998) 205-213
21. Loh K.P., Huang S.H., De Silva R., Tan B.K., and Zhu Y.Z. Oxidative stress: apoptosis in neuronal injury. Curr. Alzheimer. Res. 3 (2006) 327-337
22. Nakashima M., Niwa N., Iwai T., and Uematsu T. Involvement of free radicals in cerebral vascular reperfusion injury evaluated in a transient focal cerebral ischemia model of rat. Free Radic. Biol. Med. 26 (1999) 722-729
23. Nagasawa H., and Kogure K. Correlation between cerebral bllod flow and histologic changes in a new rat model of middle cerebral artery occlusion. Stroke 20 (1989) 1037-1043
24. Osakada F., Kawato Y., Kume T., Katsuki H., Sugimoto H., and Akaike A. Serofendic acid, a sulfur-containing diterpenoid derived from fetal calf serum, attenuates reactive oxygen species-induced oxidative stress in cultured striatal neurons. J. Pharmacol. Exp. Ther. 311 (2004) 51-59
25. Rupalla K., Allegrini P.R., Sauer D., and Wiessner C. Time course of microglia activation and apoptosis in various brain region after permanent focal cerebral ischemia in mice. Acta Neuropathol. 96 (1998) 172-178
26. Sasaki C., Kitagawa H., Zhang W.R., Warita H., Sakai K., and Abe K. Temporal profile of cytochrome c and caspase-3 immunoreactivities and TUNEL staining after permanent middle cerebral artery occlusion in rats. Neurol. Res. 22 (2000) 223-228
27. Schinzel A.C., Takeuchi O., Huang Z., Fisher J.K., Zhou Z., Rubens J., Hetz C., Danial N.N., Moskowitz M.A., and Korsmeyer S.J. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 12005-12010
28. Siesjo B.K., and Siesjo P. Mechanisms of secondary brain injury. Eur. J. Anaesthesiol. 13 (1996) 247-268
29. Sommer C., Schomacher M., Berger C., Kuhnert K., Muller H.D., Schwab S., and Schabitz W.R. Neuroprotective cannabinoid receptor antagonist SR141716A prevents downregulation of excitotoxic NMDA receptors in the ischemic penumbra. Acta Neuropathol. 112 (2006) 277-286
30. Taguchi R., Nishikawa H., Kume T., Terauchi T., Kaneko S., Katsuki H., Yonaga M., Sugimoto H., and Akaike A. Serofendic acid prevents acute glutamate neurotoxicity in cultured cortical neurons. Eur. J. Pharmacol. 477 (2003) 195-203
31. Takeda T., Akao M., Matsumoto-Ida M., Kato M., Takenaka H., Kihara Y., Kume T., Akaike A., and Kita T. Serofendic acid, a novel substance extracted from fetal calf serum, protects againt oxidative stress in neonatal rat cardiac myocytes. J. Am. Coll. Cardiol. 47 (2006) 1882-1890
32. Terauchi T., Asai N., Yonaga M., Mano N., Kume T., Akaike A., and Sugimoto H. Synthesis and absolute configuration of serofendic acids. Tetrahedron Lett. 43 (2002) 3625-3628
33. Zhang N., Komine-kobayashi M., Tanaka R., Liu M., Mizuno Y., and Urabe T. Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain. Stroke 36 (2005) 2220-2225
34. Zhao X., Liu S.J., Zhang J., Strong R., Aronowski J., and Grotta J.C. Combining insulin-like growth factor deprivatives plus caffeinol produces robust neuroprotection after stroke in rats. Stroke 36 (2005) 129-134