Protective effect of serofendic acid on glutamate-induced neurotoxicity in rat cultured motor neurons

Neuroscience Letters

Volumn 383, Issue 3, 2005, Pages 199-202

  Kume, Toshiaki ^a   Kawai, Yuko ^a   Yoshida, Kohei ^a   Nakamizo, Tomoki ^a   Kanki, Rie ^a   Sawada, Hideyuki ^a   Katsuki, Hiroshi ^a   Shimohama, Shun ^a   Sugimoto, Hachiro ^a   Akaike, Akinori ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Fetal calf serum; Glutamate; Neurotoxicity; Nitric oxide; Serofendic acid; Spinal cord

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; ARGININE DERIVATIVE; DIZOCILPINE; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; KAINIC ACID RECEPTOR; LEVO PYRROLIDINE 2,4 DECARBOXYLIC ACID; N METHYL DEXTRO ASPARTIC ACID; N(G) NITROARGININE METHYL ESTER; NEUROPROTECTIVE AGENT; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; PYRROLIDINE DERIVATIVE; S NITROSOCYSTEINE; SEROFENDIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; FETUS; MOTONEURON; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; REACTION TIME; SPINAL CORD; TISSUE CULTURE;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CYSTEINE; DICARBOXYLIC ACIDS; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; EMBRYO; GLUTAMIC ACID; MOTOR NEURONS; NEUROPROTECTIVE AGENTS; NEUROTRANSMITTER UPTAKE INHIBITORS; NITRIC OXIDE DONORS; PYRROLIDINES; RATS; S-NITROSOTHIOLS; SPINAL CORD; TIME FACTORS;

EID: 20444427981     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.04.015     Document Type: Article

References (15)

1. G. Appendino, E. Belloro, G.C. Tron, J. Jakupovic, and M. Ballero Polycyclic diterpenoids from Euphorbia characias Fitoterapia 71 2000 134 142
2. M.F. Beal, R.J. Ferrante, S.E. Browne, R.T. Matthews, N.W. Kowall, and R.H. Brown Jr. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis Ann. Neurol. 42 1997 644 654
3. G. Bensimon, L. Lacomblez, and V. Meininger A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group N. Engl. J. Med. 330 1994 585 591
4. R.J. Ferrante, S.E. Browne, L.A. Shinobu, A.C. Bowling, M.J. Baik, U. MacGarvey, N.W. Kowall, R.H. Brown Jr., and M.F. Beal Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis J. Neurochem. 69 1997 2064 2074
5. T. Kume, N. Asai, H. Nishikawa, N. Mano, T. Terauchi, R. Taguchi, H. Shirakawa, F. Osakada, H. Mori, N. Asakawa, M. Yonaga, Y. Nishizawa, H. Sugimoto, S. Shimohama, H. Katsuki, S. Kaneko, and A. Akaike Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum Proc. Natl. Acad. Sci. U.S.A. 99 2002 3288 3293
6. T. Kume, H. Kouchiyama, H. Nishikawa, T. Maeda, S. Kaneko, A. Akaike, N. Noda, and T. Fujita Ether extract of fetal calf serum protects cultured rat cortical neurons against glutamate cytotoxicity Jpn. J. Pharmacol. 73 1997 371 374
7. A.R. Lal, R.C. Cambie, P.S. Rutledge, P.D. Woodgate, C.E.F. Rickard, and G.R. Clark New oxidized ent-atisane diterpens from Urphorbia fidjian Tetrahedron Lett. 30 1989 3205 3208
8. T. Nakamizo, J. Kawamata, K. Yoshida, Y. Kawai, R. Kanki, H. Sawada, T. Kihara, H. Yamashita, H. Shibasaki, A. Akaike, and S. Shimohama Phosphodiesterase inhibitors are neuroprotective to cultured spinal motor neurons J. Neurosci. Res. 71 2003 485 495
9. J.D. Rothstein, M. Van Kammen, A.I. Levey, L.J. Martin, and R.W. Kuncl Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis Ann. Neurol. 38 1995 73 84
10. P.J. Shaw, P.G. Ince, G. Falkous, and D. Mantle Oxidative damage to protein in sporadic motor neuron disease spinal cord Ann. Neurol. 38 1995 691 695
11. T. Terauchi, N. Asai, M. Yonaga, N. Mano, T. Kume, A. Akaike, and H. Sugimoto Synthesis and absolute configuration of serofendic acids Tetrahedron Lett. 43 2002 3625 3628
12. H. Tohgi, T. Abe, K. Yamazaki, T. Murata, E. Ishizaki, and C. Isobe Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis Ann. Neurol. 46 1999 129 131
13. M. Urushitani, R. Inoue, T. Nakamizo, H. Sawada, H. Shibasaki, and S. Shimohama Neuroprotective effect of cyclic GMP against radical-induced toxicity in cultured spinal motor neurons J. Neurosci. Res. 61 2002 443 448
14. S.G. Carriedo, H.Z. Yin, and J.H. Weiss Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro J. Neurosci. 16 1996 4069 4079
15. 2+ permeable AMPA receptors and selective vulnerability of motor neurons J. Neurol. Sci. 180 2000 29 34