Introduction of a CD40L genomic fragment via a human artificial chromosome vector permits cell-type-specific gene expression and induces immunoglobulin secretion

Journal of Human Genetics

Volumn 53, Issue 5, 2008, Pages 447-453

  Yamada, Hidetoshi ^a,b   Li, Yanze C ^a   Nishikawa, Mitsuo ^b   Oshimura, Mitsuo ^b   Inoue, Toshiaki ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

Bacterial artificial chromosome (BAC); CD40 ligand (CD40L); Human artificial chromosome (HAC); Hyper IgM syndrome (HIGM); Microcell mediated chromosome transfer (MMCT)

Indexed keywords

CD40 LIGAND;

ANIMAL CELL; ANTIBODY RESPONSE; ARTICLE; ARTIFICIAL CHROMOSOME; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; BONE MARROW CULTURE; CELL SPECIFICITY; CELL STRAIN U937; CELL TYPE; CHO CELL; CONTROLLED STUDY; EXPRESSION VECTOR; FEMALE; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENE TRANSFER; GENOMIC FRAGMENT; HUMAN; HUMAN ARTIFICIAL CHROMOSOME VECTOR; HUMAN CELL; HUMAN CHROMOSOME; IMMUNOGLOBULIN PRODUCTION; LEUKEMIA CELL LINE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TRANSGENE;

ANIMALS; CD40 LIGAND; CELLS, CULTURED; CHO CELLS; CHROMOSOMES, ARTIFICIAL, HUMAN; CRICETINAE; CRICETULUS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GENOME, HUMAN; HUMANS; HYPERGAMMAGLOBULINEMIA; IMMUNOGLOBULINS; JURKAT CELLS; MICE; MICE, KNOCKOUT; U937 CELLS;

BACTERIA (MICROORGANISMS); CRICETULUS GRISEUS; MUS;

EID: 43449120120     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10038-008-0268-0     Document Type: Article

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