-
1
-
-
38949153807
-
Historical review: Megakaryopoiesis and thrombopoiesis
-
Kaushansky K. Historical review: megakaryopoiesis and thrombopoiesis. Blood 2008;111:981-6.
-
(2008)
Blood
, vol.111
, pp. 981-986
-
-
Kaushansky, K.1
-
2
-
-
31044443970
-
The biogenesis of platelets from megakaryocyte proplatelets
-
Patel SR, Hartwig JH, Italiano JE, Jr. The biogenesis of platelets from megakaryocyte proplatelets. J Clin Invest 2005;115:3348-54.
-
(2005)
J Clin Invest
, vol.115
, pp. 3348-3354
-
-
Patel, S.R.1
Hartwig, J.H.2
Italiano Jr., J.E.3
-
3
-
-
0023906446
-
Human megakaryocytopoiesis: In vitro regulation and characterization of megakaryocytic precursor cells by differentiation markers
-
Vainchenker W, Kieffer N. Human megakaryocytopoiesis: in vitro regulation and characterization of megakaryocytic precursor cells by differentiation markers. Blood Rev 1988; 2:102-7.
-
(1988)
Blood Rev
, vol.2
, pp. 102-107
-
-
Vainchenker, W.1
Kieffer, N.2
-
4
-
-
34147179036
-
Interrelation between polyploidization and megakaryocyte differentiation: A gene profiling approach
-
Raslova H, Kauffmann A, Sekkai D, Ripoche H, Larbret F, Robert T, et al. Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach. Blood 2007;109:3225-34.
-
(2007)
Blood
, vol.109
, pp. 3225-3234
-
-
Raslova, H.1
Kauffmann, A.2
Sekkai, D.3
Ripoche, H.4
Larbret, F.5
Robert, T.6
-
5
-
-
0028909690
-
Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro
-
Broudy VC, Lin NL, Kaushansky K. Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro. Blood 1995;85:1719-26.
-
(1995)
Blood
, vol.85
, pp. 1719-1726
-
-
Broudy, V.C.1
Lin, N.L.2
Kaushansky, K.3
-
6
-
-
11144356721
-
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
-
Avecilla ST, Hattori K, Heissig B, Tejada R, Liao F, Shido K, et al. Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nat Med 2004;10:64-71.
-
(2004)
Nat Med
, vol.10
, pp. 64-71
-
-
Avecilla, S.T.1
Hattori, K.2
Heissig, B.3
Tejada, R.4
Liao, F.5
Shido, K.6
-
7
-
-
0028176283
-
cMpl ligand is a humoral regulator of megakaryocytopoiesis
-
Wendling F, Maraskovsky E, Debili N, Florindo C, Teepe M, Titeux M, et al. cMpl ligand is a humoral regulator of megakaryocytopoiesis. Nature 1994;369:571-4.
-
(1994)
Nature
, vol.369
, pp. 571-574
-
-
Wendling, F.1
Maraskovsky, E.2
Debili, N.3
Florindo, C.4
Teepe, M.5
Titeux, M.6
-
8
-
-
0032400867
-
Thrombopoietin production is inhibited by a translational mechanism
-
Ghilardi N, Wiestner A, Skoda RC. Thrombopoietin production is inhibited by a translational mechanism. Blood 1998;92:4023-30.
-
(1998)
Blood
, vol.92
, pp. 4023-4030
-
-
Ghilardi, N.1
Wiestner, A.2
Skoda, R.C.3
-
9
-
-
1542615163
-
Thrombocytosis
-
Schafer AI. Thrombocytosis. N Engl J Med 2004;350:1211-9.
-
(2004)
N Engl J Med
, vol.350
, pp. 1211-1219
-
-
Schafer, A.I.1
-
10
-
-
0031975482
-
An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia
-
Wiestner A, Schlemper RJ, van der Maas AP, Skoda RC. An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia. Nat Genet 1998;18:49-52.
-
(1998)
Nat Genet
, vol.18
, pp. 49-52
-
-
Wiestner, A.1
Schlemper, R.J.2
van der Maas, A.P.3
Skoda, R.C.4
-
11
-
-
0032529663
-
Familial essential thrombocythemia associated with one-base deletion in the 5′-untranslated region of the thrombopoietin gene
-
Kondo T, Okabe M, Sanada M, Kurosawa M, Suzuki S, Kobayashi M, et al. Familial essential thrombocythemia associated with one-base deletion in the 5′-untranslated region of the thrombopoietin gene. Blood 1998;92:1091-6.
-
(1998)
Blood
, vol.92
, pp. 1091-1096
-
-
Kondo, T.1
Okabe, M.2
Sanada, M.3
Kurosawa, M.4
Suzuki, S.5
Kobayashi, M.6
-
12
-
-
0032757997
-
Hereditary thrombocythaemia in a Japanese family is caused by a novel point mutation in the thrombopoietin gene
-
Ghilardi N, Wiestner A, Kikuchi M, Ohsaka A, Skoda RC. Hereditary thrombocythaemia in a Japanese family is caused by a novel point mutation in the thrombopoietin gene. Br J Haematol 1999;107:310-6.
-
(1999)
Br J Haematol
, vol.107
, pp. 310-316
-
-
Ghilardi, N.1
Wiestner, A.2
Kikuchi, M.3
Ohsaka, A.4
Skoda, R.C.5
-
13
-
-
0033566796
-
A single-base deletion in the thrombopoietin (TPO) gene causes familial essential thrombocythemia through a mechanism of more efficient translation of TPO mRNA
-
Ghilardi N, Skoda RC. A single-base deletion in the thrombopoietin (TPO) gene causes familial essential thrombocythemia through a mechanism of more efficient translation of TPO mRNA. Blood 1999;94:1480-2.
-
(1999)
Blood
, vol.94
, pp. 1480-1482
-
-
Ghilardi, N.1
Skoda, R.C.2
-
14
-
-
43449085540
-
A de novo splice donor mutation in the thrombopoietin gene causes hereditary thrombocythemia in a Polish family
-
Liu K, Kralovics R, Rudzki Z, Grabowska B, Buser AS, Olcaydu D, et al. A de novo splice donor mutation in the thrombopoietin gene causes hereditary thrombocythemia in a Polish family. Haematologica 2008;93:706-14.
-
(2008)
Haematologica
, vol.93
, pp. 706-714
-
-
Liu, K.1
Kralovics, R.2
Rudzki, Z.3
Grabowska, B.4
Buser, A.S.5
Olcaydu, D.6
-
15
-
-
2542502506
-
Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin
-
Ding J, Komatsu H, Wakita A, Kato-Uranishi M, Ito M, Satoh A, et al. Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin. Blood 2004;103:4198-200.
-
(2004)
Blood
, vol.103
, pp. 4198-4200
-
-
Ding, J.1
Komatsu, H.2
Wakita, A.3
Kato-Uranishi, M.4
Ito, M.5
Satoh, A.6
-
16
-
-
34047236618
-
Markers of myeloproliferative diseases in childhood polycythemia vera and essential thrombocythemia
-
Teofili L, Giona F, Martini M, Cenci T, Guidi F, Torti L, et al. Markers of myeloproliferative diseases in childhood polycythemia vera and essential thrombocythemia. J Clin Oncol 2007;25:1048-53.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1048-1053
-
-
Teofili, L.1
Giona, F.2
Martini, M.3
Cenci, T.4
Guidi, F.5
Torti, L.6
-
17
-
-
3843052277
-
Mpl Baltimore: A thrombopoietin receptor polymorphism associated with thrombocytosis
-
Moliterno AR, Williams DM, Gutierrez-Alamillo LI, Salvatori R, Ingersoll RG, Spivak JL. Mpl Baltimore: a thrombopoietin receptor polymorphism associated with thrombocytosis. Proc Natl Acad Sci USA 2004;101:11444-7.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11444-11447
-
-
Moliterno, A.R.1
Williams, D.M.2
Gutierrez-Alamillo, L.I.3
Salvatori, R.4
Ingersoll, R.G.5
Spivak, J.L.6
-
18
-
-
28244442441
-
Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: A prospective study
-
Campbell PJ, Scott LM, Buck G, Wheatley K, East CL, Marsden JT, et al. Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study. Lancet 2005;366:1945-53.
-
(2005)
Lancet
, vol.366
, pp. 1945-1953
-
-
Campbell, P.J.1
Scott, L.M.2
Buck, G.3
Wheatley, K.4
East, C.L.5
Marsden, J.T.6
-
19
-
-
33746437130
-
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
-
Pikman Y, Lee BH, Mercher T, McDowell E, Ebert BL, Gozo M, et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med 2006;3:e270.
-
(2006)
PLoS Med
, vol.3
-
-
Pikman, Y.1
Lee, B.H.2
Mercher, T.3
McDowell, E.4
Ebert, B.L.5
Gozo, M.6
-
20
-
-
33750534561
-
MPL515 mutations in myeloproliferative and other myeloid disorders: A study of 1182 patients
-
Pardanani AD, Levine RL, Lasho T, Pikman Y, Mesa RA, Wadleigh M, et al. MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients. Blood 2006;108:3472-6.
-
(2006)
Blood
, vol.108
, pp. 3472-3476
-
-
Pardanani, A.D.1
Levine, R.L.2
Lasho, T.3
Pikman, Y.4
Mesa, R.A.5
Wadleigh, M.6
-
21
-
-
39749133771
-
Clinical significance of MPL mutations in essential thrombocythemia: Analysis of the PT-1 cohort [abstract]
-
Beer P, Campbell P, Erber W, Scott L, Bench A, Bareford D, et al. Clinical significance of MPL mutations in essential thrombocythemia: analysis of the PT-1 cohort [abstract]. Blood 2007;110:677.
-
(2007)
Blood
, vol.110
, pp. 677
-
-
Beer, P.1
Campbell, P.2
Erber, W.3
Scott, L.4
Bench, A.5
Bareford, D.6
-
22
-
-
43449087815
-
Relation between proportion of granulocyte JAK2 (V617F) mutant alleles, clinical phenotype and disease progression in chronic myeloproliferative disorders [abstract]
-
Passamonti F, Rumi E, Pietra D, Elena C, Della Porta M, Arcaini L, et al. Relation between proportion of granulocyte JAK2 (V617F) mutant alleles, clinical phenotype and disease progression in chronic myeloproliferative disorders [abstract]. Haematologica 2006;91 (suppl 1):350.
-
(2006)
Haematologica
, vol.91
, Issue.SUPPL. 1
, pp. 350
-
-
Passamonti, F.1
Rumi, E.2
Pietra, D.3
Elena, C.4
Della Porta, M.5
Arcaini, L.6
-
23
-
-
37049036160
-
Somatic mutations of JAK2 exon 12 as a molecular basis of erythrocytosis
-
Cazzola M. Somatic mutations of JAK2 exon 12 as a molecular basis of erythrocytosis. Haematologica 2007;92:1585-9.
-
(2007)
Haematologica
, vol.92
, pp. 1585-1589
-
-
Cazzola, M.1
-
24
-
-
34047211223
-
Anaemia characterises patients with myelofibrosis harbouring Mpl mutation
-
Guglielmelli P, Pancrazzi A, Bergamaschi G, Rosti V, Villani L, Antonioli E, et al. Anaemia characterises patients with myelofibrosis harbouring Mpl mutation. Br J Haematol 2007;137:244-7.
-
(2007)
Br J Haematol
, vol.137
, pp. 244-247
-
-
Guglielmelli, P.1
Pancrazzi, A.2
Bergamaschi, G.3
Rosti, V.4
Villani, L.5
Antonioli, E.6
-
25
-
-
38549087966
-
Myelodysplastic/myeloproliferative disorders
-
Malcovati L, Cazzola M. Myelodysplastic/myeloproliferative disorders. Haematologica 2008;93:4-6.
-
(2008)
Haematologica
, vol.93
, pp. 4-6
-
-
Malcovati, L.1
Cazzola, M.2
-
26
-
-
33744478891
-
Occurrence of the JAK2 V617F mutation in the WHO provisional entity: Myelodysplastic/myeloproliferative disease, unclassifiable-refractory anemia with ringed sideroblasts associated with marked thrombocytosis
-
Remacha AF, Nomdedeu JF, Puget G, Estivill C, Sarda MP, Canals C, et al. Occurrence of the JAK2 V617F mutation in the WHO provisional entity: myelodysplastic/myeloproliferative disease, unclassifiable-refractory anemia with ringed sideroblasts associated with marked thrombocytosis. Haematologica 2006;91:719-20.
-
(2006)
Haematologica
, vol.91
, pp. 719-720
-
-
Remacha, A.F.1
Nomdedeu, J.F.2
Puget, G.3
Estivill, C.4
Sarda, M.P.5
Canals, C.6
-
27
-
-
37749011577
-
MPL W515 and JAK2 V617 mutation analysis in patients with refractory anemia with ringed sideroblasts and an elevated platelet count
-
Steensma DP, Caudill JS, Pardanani A, McClure RF, Lasho TL, Tefferi A. MPL W515 and JAK2 V617 mutation analysis in patients with refractory anemia with ringed sideroblasts and an elevated platelet count. Haematologica 2006;91:ECR57.
-
(2006)
Haematologica
, vol.91
-
-
Steensma, D.P.1
Caudill, J.S.2
Pardanani, A.3
McClure, R.F.4
Lasho, T.L.5
Tefferi, A.6
-
28
-
-
38549176801
-
JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis
-
Schmitt-Graeff AH, Teo SS, Olschewski M, Schaub F, Haxelmans S, Kirn A, et al. JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis. Haematologica 2008;93:34-40.
-
(2008)
Haematologica
, vol.93
, pp. 34-40
-
-
Schmitt-Graeff, A.H.1
Teo, S.S.2
Olschewski, M.3
Schaub, F.4
Haxelmans, S.5
Kirn, A.6
-
29
-
-
35748956094
-
Gene expression profiling of CD34+ cells in patients with the 5q- syndrome
-
Boultwood J, Pellagatti A, Cattan H, Lawrie CH, Giagounidis A, Malcovati L, et al. Gene expression profiling of CD34+ cells in patients with the 5q- syndrome. Br J Haematol 2007;139:578-89.
-
(2007)
Br J Haematol
, vol.139
, pp. 578-589
-
-
Boultwood, J.1
Pellagatti, A.2
Cattan, H.3
Lawrie, C.H.4
Giagounidis, A.5
Malcovati, L.6
-
30
-
-
0033039333
-
Aetiology and clinical significance of thrombocytosis: Analysis of 732 patients with an elevated platelet count
-
Griesshammer M, Bangerter M, Sauer T, Wennauer R, Bergmann L, Heimpel H. Aetiology and clinical significance of thrombocytosis: analysis of 732 patients with an elevated platelet count. J Intern Med 1999;245:295-300.
-
(1999)
J Intern Med
, vol.245
, pp. 295-300
-
-
Griesshammer, M.1
Bangerter, M.2
Sauer, T.3
Wennauer, R.4
Bergmann, L.5
Heimpel, H.6
-
31
-
-
0034210637
-
Translational pathophysiology: A novel molecular mechanism of human disease
-
Cazzola M, Skoda RC. Translational pathophysiology: a novel molecular mechanism of human disease. Blood 2000;95:3280-8.
-
(2000)
Blood
, vol.95
, pp. 3280-3288
-
-
Cazzola, M.1
Skoda, R.C.2
-
32
-
-
33644501833
-
Increased platelet and leukocyte activation as contributing mechanisms for thrombosis in essential thrombocythemia and correlation with the JAK2 mutational status
-
Arellano-Rodrigo E, Alvarez-Larran A, Reverter JC, Villamor N, Colomer D, Cervantes F. Increased platelet and leukocyte activation as contributing mechanisms for thrombosis in essential thrombocythemia and correlation with the JAK2 mutational status. Haematologica 2006; 91:169-75.
-
(2006)
Haematologica
, vol.91
, pp. 169-175
-
-
Arellano-Rodrigo, E.1
Alvarez-Larran, A.2
Reverter, J.C.3
Villamor, N.4
Colomer, D.5
Cervantes, F.6
-
33
-
-
0031668547
-
The activating splice mutation in intron 3 of the thrombopoietin gene is not found in patients with nonfamilial essential thrombocythaemia
-
Harrison CN, Gale RE, Wiestner AC, Skoda RC, Linch DC. The activating splice mutation in intron 3 of the thrombopoietin gene is not found in patients with nonfamilial essential thrombocythaemia. Br J Haematol 1998;102:1341-3.
-
(1998)
Br J Haematol
, vol.102
, pp. 1341-1343
-
-
Harrison, C.N.1
Gale, R.E.2
Wiestner, A.C.3
Skoda, R.C.4
Linch, D.C.5
-
34
-
-
25844453885
-
Lessons from familial myeloproliferative disorders
-
Skoda R, Prchal JT. Lessons from familial myeloproliferative disorders. Semin Hematol 2005;42:266-73.
-
(2005)
Semin Hematol
, vol.42
, pp. 266-273
-
-
Skoda, R.1
Prchal, J.T.2
-
35
-
-
37049034302
-
Familial chronic myeloproliferative disorders: Clinical phenotype and evidence of disease anticipation
-
Rumi E, Passamonti F, Della Porta MG, Elena C, Arcaini L, Vanelli L, et al. Familial chronic myeloproliferative disorders: clinical phenotype and evidence of disease anticipation. J Clin Oncol 2007;25:5630-5.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5630-5635
-
-
Rumi, E.1
Passamonti, F.2
Della Porta, M.G.3
Elena, C.4
Arcaini, L.5
Vanelli, L.6
-
36
-
-
38949160429
-
Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders
-
Pietra D, Li S, Brisci A, Passamonti F, Rumi E, Theocharides A, et al. Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders. Blood 2008;111:1686-9.
-
(2008)
Blood
, vol.111
, pp. 1686-1689
-
-
Pietra, D.1
Li, S.2
Brisci, A.3
Passamonti, F.4
Rumi, E.5
Theocharides, A.6
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