Genetic association of interleukin-1 haplotypes with gastritis and precancerous lesions in North Indians

Clinical and Experimental Medicine

Volumn 8, Issue 1, 2008, Pages 23-29

  Achyut, B R ^a   Moorchung, N ^a   Mittal, B ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Genetic association; Polymorphism; Proinflammatory cytokines; Risk

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN G; INTERLEUKIN 1; UREASE;

ADULT; ARTICLE; ATROPHY; CELL INFILTRATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTRITIS; GASTROINTESTINAL ENDOSCOPY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HETEROZYGOTE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INDIAN; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; POLYMERASE CHAIN REACTION; PRECANCER; PRIORITY JOURNAL; STOMACH BIOPSY;

ADULT; FEMALE; GASTRITIS; HAPLOTYPES; HELICOBACTER PYLORI; HUMANS; INDIANS, NORTH AMERICAN; INTERLEUKIN-1BETA; MALE; POLYMORPHISM, GENETIC; PRECANCEROUS CONDITIONS; RECEPTORS, INTERLEUKIN-1;

HELICOBACTER PYLORI;

EID: 43449086400     PISSN: 15918890     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10238-008-0152-4     Document Type: Article

References (34)

1. Correa P (1992) Human gastric carcinogenesis: a multi-step and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res 52:6735-6740
2. Graham DY, Yamaoka Y (1998) H. pylori and cagA: relationships with gastric cancer, duodenal ulcer, and reflux esophagitis and its complications. Helicobacter 3:145-151
3. Peek RM Jr, Moss SF, Tham KT et al (1997) Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis. J Natl Cancer Inst 89:863-868
4. Xia HH-X, Talley NJ (2001) Apoptosis in gastric epithelium induced by Helicobacter pylori infection: implications in gastric carcinogenesis. Am J Gastroenterol 96:16-26
5. Kumar S, Dhar A, Srinivasan S et al (1998) Antibodies to CagA protein are not predictive of serious gastroduodenal disease in Indian patients. Indian J Gastroenterol 17:123-125
6. El-Omar EM, Carrington M, Chow WH et al (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404:398-402
7. Mansfield JC, Holden H, Tarlow JK et al (1994) Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist. Gastroenterology 106:637-642
8. Machado JC, Figueiredo C, Canedo P et al (2003) A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology 125:364-371
9. Dinarello CA (2000) The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. N Engl J Med 343:732-734
10. Figueiredo C, Machado JC, Pharoah P et al (2002) Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst 94:1680-1687
11. Bidwell J, Keen L, Gallagher G et al (1999) Cytokine gene polymorphism in human disease: on-line databases. Genes Immun 1:3-19
12. Santtila S, Savinainen K, Hurme M (1998) Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro. Scand J Immunol 47:195-198
13. Rad R, Prinz C, Neu B et al (2003) Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa. J Infect Dis 188:272-281
14. Rad R, Dossumbekova A, Neu B et al (2004) Cytokine gene polymorphisms influencee mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection. Gut 53:1082-1089
15. Gill HH, Desai HG, Majmudar P et al (1993) Epidemiology of Helicobacter pylori: the Indian scenario. Indian J Gastroenterol 12:9-11
16. Singh K, Ghoshal UC (2006) Causal role of Helicobacter pylori infection in gastric cancer: an Asian enigma. World J Gastroenterol 12:1346-1351
17. Ghoshal UC, Tiwari S, Dhingra S et al. Frequency of Helicobacter pylori and CagA antibody in patients with gastric neoplasms and controls: the Indian enigma. Dig Dis Sci (in press)
18. Ghoshal UC, Tripathi S, Ghoshal U (2007) The Indian enigma of frequent H. pylori infection but infrequent gastric cancer: is the magic key in the Indian diet, host's genetic make up, or friendly bug? Am J Gastroenterol 102:2113-2114
19. Moorchung N, Srivastava AN, Gupta NK et al (2007) Cytokine gene polymorphisms and the pathology of chronic gastritis. Singapore Med J 48:447-454
20. Dixon MF, Genta RM, Yardley JH, Correa P (1996) Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 20:1161-1181
21. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215
22. Tarlow JK, Blakemore AI, Lennard A et al (1993) Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat. Hum Genet 91:403-404
23. Schneider S, Roessli D, Excoffier L (2000) Arlequin ver. 2000: a software for population genetics data analysis. Genetics and Biometry Laboratory, University of Geneva, Switzerland
24. Sham PC, Curtis D (1995) Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann Hum Genet 59:97-105
25. Lee I, Lee H, Kim M et al (2005) Ethnic difference of Helicobacter pylori gastritis: Korean and Japanese gastritis is characterized by male-and antrum-predominant acute foveolitis in comparison with American gastritis. World J Gastroenterol 11:94-98
26. Blaser MJ (1998) Helicobacter pylori and gastritis diseases. Br Med J 316:1507-1510
27. Zhang C, Yamada N (2005) Comparison of Helicobacter pylori infection and gastric mucosal histological features of gastric ulcer patients with chronic gastritis patients. World J Gastroenterol 11:976-981
28. Kato S, Onda M, Yamada S et al (2001) Association of the interleukin-1 beta genetic polymorphism and gastric cancer risk in Japanese. J Gastroenterol 36:696-699
29. Furuta T, El-Omar EM, Xiao F et al (2002) Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology 123:92-105
30. Wilkinson RJ, Patel P, Llewelyn M et al (1999) Influence of polymorphism in the genes for the interleukin (IL)-1 receptor antagonist and IL-1beta on tuberculosis. J Exp Med 189:1863-1874
31. Hurme M, Santtila S (1998) IL-1 receptor antagonist (IL-1RA) plasma levels are co-ordinately regulated by both IL-1R and IL-1beta genes. Eur J Immunol 28:2598-2602
32. Lu B, Chen MT, Fan YH et al (2005) Effects of Helicobacter pylori eradication on atrophic gastritis and intestinal metaplasia: a 3-year follow-up study. World J Gastroenterol 11:6518-6520
33. Malfertheiner P, Fry LC, Monkemuller K (2006) Can gastric cancer be prevented by Helicobacter pylori eradication? Best Pract Res Clin Gastroenterol 20:709-719
34. Zabaleta J, Camargo MC, Piazuelo MB et al (2006) Association of interleukin-1beta gene polymorphisms with precancerous gastric lesions in African Americans and Caucasians. Am J Gastroenterol 101:163-171