Synthesis of 3′-fluoro-2′,3′-dideoxy-2′,3′- didehydro-4′-ethynyl-D- and -L-furanosyl nucleosides

Journal of Organic Chemistry

Volumn 69, Issue 18, 2004, Pages 6034-6041

  Chen, Xin ^a   Zhou, Wen ^a   Schinazi, Raymond F ^b   Chu, Chung K ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXICITY; DEPROTECTION; NUCLEOSIDES; SUGAR MOIETIES;

ACETYLATION; CONDENSATION; OXIDATION; SUGAR (SUCROSE); SYNTHESIS (CHEMICAL); TOXICITY;

ALDEHYDES;

2,3 DIDEOXY 2,3 DIDEHYDRO 3 FLUORO 4 ETHYNYL 5 O BENZOYL 1 O ACETYL FURANOSE; 3' FLUORO 2',3' DIDEOXY 2',3' DIDEHYDRO 4' ETHYNYL NUCLEOSIDE; ABACAVIR; ADENINE DERIVATIVE; ANTIRETROVIRUS AGENT; NUCLEOSIDE DERIVATIVE; STAVUDINE; UNCLASSIFIED DRUG; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; FURAN DERIVATIVE; NUCLEOSIDE;

ANTIVIRAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; FLUORINATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS; COMBINATORIAL CHEMISTRY; STEREOISOMERISM;

ANTI-HIV AGENTS; COMBINATORIAL CHEMISTRY TECHNIQUES; FURANS; MOLECULAR STRUCTURE; NUCLEOSIDES; STEREOISOMERISM;

EID: 4344714661     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo049597h     Document Type: Article

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