A quantitative trait locus influencing fasting plasma glucose in chromosome region 18q22-23

Diabetes

Volumn 53, Issue 9, 2004, Pages 2487-2491

  Li, Wei Dong ^a   Dong, Chuanhui ^a   Li, Ding ^a   Garrigan, Cathleen ^a   Price, R Arlen ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

ARTICLE; AUTOSOME; BODY MASS; BODY WEIGHT; CHROMOSOME 18Q; CHROMOSOME 2; DIABETES MELLITUS; EUROPEAN AMERICAN; FAMILY STUDY; FASTING BLOOD GLUCOSE; GENETIC LINKAGE; GENETIC TRAIT; GLUCOSE BLOOD LEVEL; HUMAN; LOGARITHM OF ODDS; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; MULTIGENIC TRAIT; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; REGRESSION ANALYSIS; VARIANCE;

BLOOD GLUCOSE; CHROMOSOMES, HUMAN, PAIR 18; DIABETES MELLITUS, TYPE 2; FASTING; HUMANS; LOD SCORE; OBESITY; PHENOTYPE; QUANTITATIVE TRAIT LOCI;

EID: 4344672416     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.9.2487     Document Type: Article

References (23)

1. Sacks DB, Bruns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M: Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 48:436-472, 2002
2. Reaven G, Abbasi F, McLaughlin T: Obesity, insulin resistance, and cardiovascular disease. Recent Prog Horm Res 59:207-223, 2004
3. Henkin L, Bergman RN, Bowden DW, Ellsworth DL, Haffner SM, Langefeld CD, Mitchell BD, Norris JM, Rewers M, Saad MF, Stamm E, Wagenknecht LE, Rich SS: Genetic epidemiology of insulin resistance and visceral adiposity: the IRAS Family Study design and methods. Ann Epidemiol 13:211-217, 2003
4. Freeman MS, Mansfield MW, Barrett JH, Grant PJ: Heritability of features of the insulin resistance syndrome in a community-based study of healthy families. Diabet Med 19:994-999, 2002
5. 1c in a community-based sample of Caucasian pedigrees: the Framingham Offspring Study. Diabetes 51:833-840, 2002
6. Watanabe RM, Ghosh S, Langefeld CD, Valle TF, Hauser ER, Magnuson VL, Mohlke KL, Silander K, Ally DS, Chines P, Blaschak-Harvan J, Douglas JA, Duren WL, Epstein MP, Fingerlin TE, Kaleta HS, Lange EM, Li C, McEachin RC, Stringham HM, Trager E, White PP, Balow Jr J, Birznieks G, Chang J, Eldridge W: The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci. Am J Hum Genet 67:1186-1200, 2000
7. Bray MS, Boerwinkle E, Hanis CL: Linkage analysis of candidate obesity genes among the Mexican-American population of Starr County, Texas. Genet Epidemiol 16:397-411, 1999
8. Price RA, Reed DR, Lee JH: Obesity related phenotypes in families selected for extreme obesity and leanness. Int J Obes Relat Metab Disord 22:406-413, 1998
9. Sham PC, Purcell S, Cherny SS, Abecasis GR: Powerful regression-based quantitative-trait linkage analysis of general pedigrees. Am J Hum Genet 71:238-253, 2002
10. Holmes DI, Wahab NA, Mason RM: Cloning and characterization of ZNF236, a glucose-regulated Kruppel-like zinc-finger gene mapping to human chromosome 18q22-q23. Genomics 60:105-109, 1999
11. Walli R, Schafer H, Morys-Wortmann C, Paetzold G, Nustede R, Schmidt WE: Identification and biochemical characterization of the human brain galanin receptor. J Mol Endocrinol 13:347-356, 1994
12. Lorimer DD, Benya RV: Cloning and quantification of galanin-1 receptor expression by mucosal cells lining the human gastrointestinal tract. Biochem Biophys Res Commun 222:379-385, 1996
13. Li WD, Dong C, Li D, Zhao H, Price RA: An obesity-related locus in chromosome region 12q23-24. Diabetes 53:812-820, 2004
14. Imperatore G, Knowler WC, Nelson RG, Hanson RL: Genetics of diabetic nephropathy in the Pima Indians. Curr Diab Rep 1:275-281, 2001
15. Vardarli I, Baier LJ, Hanson RL, Akkoyun I, Fischer C, Rohmeiss P, Basci A, Bartram CR, Van Der Woude FJ, Janssen B: Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23. Kidney Int 62:2176-2183, 2002
16. Lindgren CM, Widen E, Tuomi T, Li H, Almgren P, Kanninen T, Melander O, Weng J, Lehto M, Groop LC: Contribution of known and unknown susceptibility genes to early-onset diabetes in Scandinavia: evidence for heterogeneity. Diabetes 51:1609-1617, 2002
17. Merriman TR, Eaves IA, Twells RC, Merriman ME, Danoy PA, Muxworthy CE, Hunter KM, Cox RD, Cucca F, McKinney PA, Shield JP, Baum JD, Tuomilehto J, Tuomilehto-Wolf E, Ionesco-Tirgoviste C, Joner G, Thorsby E, Undlien DE, Pociot F, Nerup J, Ronningen KS, Bain SC, Todd JA: Transmission of haplotypes of microsatellite markers rather than single marker alleles in the mapping of a putative type 1 diabetes susceptibility gene (IDDM6). Hum Mol Genet 7:517-524, 1998
18. Yeo GS, Farooqi IS, Aminian S, Halsall DJ, Stanhope RG, O'Rahilly S: A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nat Genet 20:111-112, 1998
19. Vaisse C, Clement K, Guy-Grand B, Froguel P: A frameshift mutation in human MC4R is associated with a dominant form of obesity (Letter). Nat Genet 20:113-114, 1998
20. Hinney A, Schmidt A, Nottebom K, Heibult O, Becker I, Ziegler A, Gerber G, Sina M, Gorg T, Mayer H, Siegfried W, Fichter M, Remschmidt H, Hebebrand J: Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans. J Clin Endocrinol Metab 84:1483-1486, 1999
21. Rice T, Chagnon YC, Perusse L, Borecki IB, Ukkola O, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC: A genome-wide linkage scan for abdominal subcutaneous and visceral fat in black and white families: the HERITAGE Family Study. Diabetes 51:848-855, 2002
22. Lahiri DK, Nurnberger JI Jr: A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acid Res 19:5444, 1991
23. Abecasis GR, Cherny SS, Cookson WO, Cardon LR: Merlin: rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 30:97-101, 2002