Wegener's granulomatosis is associated with organ-specific antiendothelial cell antibodies

Kidney International

Volumn 66, Issue 3, 2004, Pages 1049-1060

  Holmén, Carolina ^b   Christensson, Marta ^b   Pettersson, Erna ^b   Bratt, Johan ^b   Stjärne, Pär ^b   Karrar, Azza ^b   Sumitran Holgersson, Suchitra ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b NONE

Author keywords

Antiendothelial cell antibodies; Inflammatory cytokines; Microscopic polyangiitis; Primary vasculitis; Wegener's granulomatosis

Indexed keywords

ENDOTHELIAL CELL ANTIBODY; GAMMA INTERFERON; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANTIGEN BINDING; ARTICLE; CELL AGGLUTINATION; CELL STRUCTURE; CLINICAL ARTICLE; COMPLEMENT FIXATION TEST; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; ENDOTHELIUM CELL; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY DISEASE; MALE; PHENOTYPE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC VASCULITIS; WEGENER GRANULOMATOSIS;

EID: 4344652875     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2004.00853.x     Document Type: Article

References (37)

1. RUSSELL KA, WIEGERT E, SCHROEDER DR, et al: Detection of antineutrophil cytoplasmic antibodies under actual clinical testing conditions. Clin Immunol 103:196-203, 2002
2. DAY C, SAVAGE C: Primary systemic vasculitis. Minerva Medica 92:349-363, 2001
3. HOFFMAN G, SPECKS U: Antineutrophil cytoplasmic antibodies. Arthritis Rheum 41:1521-1537, 1998
4. DEL PAPA N, COMFORTI G, GAMBINI D, et al: Characterization of the surface proteins recognized by anti-endothelial antibodies in primary autoimmune vasculitis. Clin Immunol Immunopathol 70:211-216, 1996
5. GOBEL U, EICHHORN J, KETTRITZ R, et al: Disease activity and autoantibodies to endothelial cells in patients with Wegener's granulomatosis. Am J Kidney Dis 28:186-194, 1996
6. DEL PAPA N, GUIDALI L, SIRONI M, et al: Anti-endothelial cell IgG antibodies from patients with Wegener's granulomatosis binds to human endothelial cell in vitro and induce adhesion molecule expression and cytokine secretion cells. Arthritis Rheum 39:758-766, 1996
7. DAMIANOVICH M, GILBURD B, GEORGE J, et al: Pathogenic role of anti-endothelial cell antibodies in vasculitis. An idiotypic experimental model. J Immunol 156:4946-4951, 1996
8. CHAN TM, FRAMPTON G, JAYNE DR, et al: Clinical significance of anti-endothelial cell antibodies in systemic vasculitis: A longitudinal study comparing anti-endothelial cell antibodies and antineutrophil cytoplasm antibodies. Am J Kidney Dis 22:387-392, 1993
9. PAGE A, ROSE M, YACOUB M, PIGOTT R: Antigenic heterogeneity of vascular endothelium. Am J Pathol 141:673-683, 1992
10. TSUKADA N, TANAKA Y, MIYAGI K, et al: Autoantibodies to each protein fraction extracted from cerebral endothelial cell membrane in the sera of patients with multiple sclerosis. J Neurol 24:41-46, 1989
11. TROJANO M, DEFAZIO G, RICCHIATI F, et al: Serum IgG to brain microvascular endothelial cells in multiple sclerosis. J Neurol Sci 143:107-113, 1996
12. PRAPROTNIK S, BLANK M, LEVY Y, et al: Anti-endothelial cell antibodies from patients with thrombotic thrombocytopenic purpura specifically activate small vessel endothelial cells. Int Immunol 13:203-210, 2001
13. BLANK M, KRAUSE I, GOLDKORN T, et al: Monoclonal anti-endothelial cell antibodies from a patient with Takayasu arteritis activate endothelial cells from large vessels. Arthritis Rheum 42:1421-1432, 1999
14. JEANNETTE CJ, FALK RJ, ANDRASSY K, et al: Nomenclature of systemic vasculitides: Proposal of an international consensus conference. Arthritis Rheum 37:187-192, 1994
15. LUQMANI R, BACON PA, MOOTS RJ, et al: Birmingham vasculitis activity score (BVAS) in systemic necrotizing vasculitis. Q J Med 87:671-678, 1994
16. DANEKER GW, LUND SA, CAUGHMAN SW, et al: Culture and characterization of sinusoidal endothelial cells isolated from human liver. In vitro Cell Dev Biol 34:370-377, 1998
17. BO X, BROOMÉ U, UZUNEL M, et al: Capillarization of hepatic sinusoid by liver endothelial cell-reactive autoantibodies in patients with cirrhosis and chronic hepatitis. Am J Pathol 163:1275-1289, 2003
18. BO X, BROOMÉ U, REMBERGER M, SUMITRAN-HOLGERSSON S: Tumor necrosis factor α impairs function of liver derived lymphocytes and natural killer cells in patients with primary sclerosing cholangitis. Gut 49:131-141, 2001
19. SUMITRAN-KARUPPAN S, LINDHOLM A, MÖLLER E: Fewer acute rejection episodes and improved outcome in kidney transplanted patients with changed selection of criteria based on cross-matching? Transplantation 53:666-673, 1992
20. SUMITRAN-KARUPPAN S, MÖLLER E: Specific inhibition of HLA class I and II antibodies by soluble antigens - A method for the identification of antibody specificity in serum from alloimmunized individuals. Transplantation 58:713-719, 1994
21. LINDQUIST KJ, OSTERLAND CK: Human antibodies to vascular endothelium. Clin Exp Immunol 9:753-760, 1971
22. TAN EM, PEARSON CM: Rheumatic disease sera reactive with capillaries in the mouse kidney. Arthritis Rheum 15:23-28, 1972
23. HASHEMI S, SMITH CD, IZAGUIRRE CA: Anti-endothelial cell antibodies: Detection and characterization using a cellular enzyme-linked immunosorbent assay. J Lab Clin Med 109:434-440, 1987
24. ROSENBAUM J, POTTINGER BE, WOO P, et al: Measurement and characterisation of circulating anti-endothelial cell IgG in connective tissue disease. Clin Exp Immunol 72:450-456, 1988
25. WESTPHAL JR, BOERBOOMS AMT, SCHALKWIJK CJM, et al: Anti-EC antibodies in sera of patients with autoimmune disease: Comparison between ELISA and FACS analysis. Clin Exp Immunol 96:444-449, 1994
26. KELLENBERGER E, JOHANSEN R, MAEDER M, et al: Artefacts and morphological changes during chemical fixation. J Microscopy 168:181-201, 1992
27. DROVER S, MARSHALL WH: Glutaraldehyde fixation of target cells to plastic for ELISA assays of monoclonal anti-HLA antibodies produces artefacts. J Immunol Methods 90:275-281, 1986
28. PERROT JY, KRIEF P, JULIEN C, et al: Screening monoclonal antibodies against cell-surface antigens. High frequency of natural antibodies. Scand J Immunol 23:623-629, 1986
29. RIBATTI D, NICO B, VACCA A, et al: Endothelial cell heterogeneity and organ specificity. J Hematotherapy Stem Cell Res 11:81-90, 2002
30. AIRD WC: Endothelial cell heterogeneity. Crit Care Med 31:S221-S230, 2003
31. STASTNY P: Endothelial-monocyte antigens. Transplant Proc 12 (3 Suppl 1):32-36, 1980
32. BRASILE L, RODMAN E, SHIELD CFD, et al: The association of anti-vascular endothelial cell antibody with hyperacute rejection: A case report. Surgery 99:637-640, 1986
33. CERILLI J, BRASILE L: Endothelial cell alloantigens. Transplant Proc 12 (3 Suppl 1):37-42, 1980
34. MERONI PL, DEL PAPA N, RASCHI E, et al: Is there any pathogenic role for the anti-endothelial cell antibodies (AECA) in autoimmune vasculitis. J Biol Regul Homeost Agents 11:127-132, 1997
35. LEUNG DY, MOAKE JL, HAVENS PL, et al: Lytic anti-endothelial cell antibodies in haemolytic-uraemic syndrome. Lancet 2:183-186, 1988
36. YAMAOKA J, KABASHIMA K, KAWANISHI M, et al: Cytotoxicity of IFN-gamma and TNF-alpha for vascular endothelial cell is mediated by nitric oxide. Biochem Biophy Res Com 291:780-786, 2002
37. HOLLER N, ZARU R, MICHEAU O, et al: Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1:489-495, 2000