Endothelin: Role in experimental hypertension

Journal of Cardiovascular Pharmacology

Volumn 35, Issue SUPPL. 2, 2000, Pages

  Schiffrin, E L ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

Insulin resistance; Mineralocorticoid; Salt sensitivity; Vascular hypertrophy

Indexed keywords

ANGIOTENSIN; DEOXYCORTICOSTERONE ACETATE; ENDOTHELIN; ENDOTHELIN RECEPTOR ANTAGONIST; FRUCTOSE; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; ANGIOTENSIN II; DEOXYCORTICOSTERONE; ENDOTHELIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONTROLLED STUDY; DISEASE SEVERITY; HEREDITY; HYPERTENSION; INSULIN RESISTANCE; KIDNEY FAILURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENOVASCULAR HYPERTENSION; REVIEW; STROKE; VASCULARIZATION; ANIMAL; BLOOD; CHEMICALLY INDUCED DISORDER; DAHL SALT SENSITIVE RAT; DISEASE MODEL; PATHOPHYSIOLOGY; PHYSIOLOGY; SPONTANEOUSLY HYPERTENSIVE RAT;

ANGIOTENSIN II; ANIMALS; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; ENDOTHELIN-1; FRUCTOSE; HYPERTENSION; INSULIN RESISTANCE; NG-NITROARGININE METHYL ESTER; RATS; RATS, INBRED DAHL; RATS, INBRED SHR;

EID: 0033667710     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200000002-00008     Document Type: Review

References (12)

1. Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate-salt hypertensive but not in spontaneously hypertensive rats
2. Deoxycorticosterone acetate plus salt induce overexpression of vascular endothelin-1 and severe vascular hypertrophy in spontaneously hypertensive rats
3. Endothelin antagonists in salt-dependent hypertension associated with renal insufficiency
4. Effect of chronic endothelin blockade in hyperinsulinemic hypertensive rats
5. Effect of a nonselective endothelin antagonist on vascular remodeling in DOCA-salt hypertensive rats. Evidence for a role of endothelin in vascular hypertrophy
6. Effect of chronic ET(A)-selective endothelin receptor antagonism on blood pressure in experimental and genetic hypertension in rats
7. Endothelin: Potential role in hypertension and vascular hypertrophy
8. Clinical significance of endothelin in cardiovascular disease
9. Endothelin A receptor blockade alleviates hypertension and renal lesions associated with chronic nitric oxide synthase inhibition
10. Angiotensin II increases tissue endothelin and induces vascular hypertrophy - Reversal by ETA-receptor antagonist
11. Vascular and cardiac overexpression of endothelin-1 gene in one-kidney one clip Goldblatt hypertensive rats but only in the late phase of two-kidney one clip Goldblatt hypertension
12. Structure and function of small arteries in salt-induced hypertension - Effects of chronic endothelin-subtype-A-receptor blockade