Contribution of endogenous endothelin-1 and endothelin-A-receptors to the hypertensive state of endothelin-B heterozygous (+/-) knockout mice

Journal of Cardiovascular Pharmacology

Volumn 36, Issue 5 SUPPL. 1, 2000, Pages

  Berthiaume, N ^a   Yanagisawa, M ^a   D'Orleans Juste, P ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

ET(B) receptors; Hypertension; Knockout; Mouse; Plasmatic clearance

Indexed keywords

BQ 928; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE;

ANIMAL MODEL; ARTICLE; HYPERTENSION; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL;

EID: 0033755604     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200036001-00062     Document Type: Article

References (7)

1. Heart and lung disease in engineered mice
2. Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1
3. Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice
4. Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
5. Renal sympathetic nerve activity in mice: Comparison between mice and rats and between normal and endothelin-1 deficient mice
6. Elevation of blood pressure by genetic and pharmacological disruption of the ET(B) receptor in mice
7. Clearance of circulating endothelin-1 by ET(B) receptors in rats