Enhancement of transfection efficiency through rapid and noncovalent post-PEGylation of poly(dimethylaminoethyl methacrylate)/DNA complexes

Pharmaceutical Research

Volumn 21, Issue 8, 2004, Pages 1471-1479

  Pirotton, Sabine ^a   Muller, Caroline ^b   Pantoustier, Nadège ^c   Botteman, François ^c   Collinet, Sébastien ^a   Grandfils, Christian ^b   Dandrifosse, Guy ^b   Degée, Philippe ^c   Dubois, Philippe ^c   Raes, Martine ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF MONS   (Belgium)

Author keywords

atom transfer radical polymerization; gene delivery; pegylation; transfection

Indexed keywords

COPOLYMER; DIMETHYL ETHER; DNA; MACROGOL; METHACRYLIC ACID DERIVATIVE; POLY[2 (DIMETHYLAMINO)ETHYL METHACRYLATE]; POLY[2 (DIMETHYLAMINO)ETHYLMETHACRYLATE B POLY(ETHYLENE GLYCOL) ALPHA METHYL ETHER OMEGA METHACRYLATE]; POLYMER; UNCLASSIFIED DRUG;

ADDITION REACTION; ANIMAL CELL; ARTICLE; ATOM TRANSFER RADICAL POLYMERIZATION; BLOOD CELL; CELL STRAIN COS7; CHEMICAL MODIFICATION; ELECTROPHORETIC MOBILITY; EX VIVO STUDY; GENETIC TRANSFECTION; LIGHT SCATTERING; MEASUREMENT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PEGYLATION; PLASMID; PRIORITY JOURNAL; SERUM; STATISTICAL SIGNIFICANCE; SURFACE PROPERTY; THROMBOCYTE COUNT; ZETA POTENTIAL;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DNA; ERYTHROCYTE AGGREGATION; HEMOLYSIS; METHACRYLATES; NYLONS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS; TRANSFECTION;

EID: 4344594697     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000036923.25772.97     Document Type: Article

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