A gene-expression signature can quantify the degree of hepatic fibrosis in the rat

Journal of Hepatology

Volumn 41, Issue 3, 2004, Pages 399-406

  Utsunomiya, Tohru ^a   Okamoto, Masahiro ^a   Hashimoto, Masaji ^b   Yoshinaga, Keiji ^a   Shiraishi, Takeshi ^a   Tanaka, Fumiaki ^a   Mimori, Koshi ^a   Inoue, Hiroshi ^a   Watanabe, Goro ^b   Barnard, Graham F ^c   Mori, Masaki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b TORANOMON HOSPITAL   (Japan)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Carcinogenesis; cDNA microarray; Fibrogenesis; Liver fibrosis; Scoring system

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CLONE; CHEMICAL PROCEDURES; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION; GENE FUNCTION; LEARNING; LIVER CIRRHOSIS; LIVER FIBROSIS; MALE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SIGNAL NOISE RATIO;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; DOWN-REGULATION; GENE EXPRESSION PROFILING; LIVER CIRRHOSIS, EXPERIMENTAL; LIVER NEOPLASMS, EXPERIMENTAL; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 4344576756     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2004.05.015     Document Type: Article

References (41)

1. T.J. Liang, B. Reherman, L.B. Seeff, and J.H. Hoofnagle Pathogenesis, natural history, treatment and prevention of hepatitis C Ann Intern Med 132 2000 296 305
2. L.B. Seeff Natural history of hepatitis C Hepatology 36 2002 S35 S46
3. D.A. Brenner, T. Waterboer, S.K. Choi, J.N. Lindquist, B. Stefanovic, and E. Burchardt New aspects of hepatic fibrosis J Hepatol 32 2000 32 38
4. S.L. Friedman Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury J Biol Chem 275 2000 2247 2250
5. R.G. Knodell, K.G. Ishak, W.C. Black, T.S. Chen, R. Craig, and N. Kaplowitz Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis Hepatology 1 1981 431 435
6. V. Desmet, M. Gerber, J.H. Hoofnagle, M. Manns, and P. Scheuer Classification of chronic hepatitis: diagnosis, grading and staging Hepatology 19 1994 1513 1520
7. P. Beddosa, T. Poynard, and The Metavir Cooperative Group Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C Hepatology 20 1994 15 20
8. J. Westin, L.M. Lagging, R. Wejstal, G. Norkans, and A.P. Dhillon Interobserver study of liver histopathology using the Ishak score in patients with chronic hepatitis C virus infection Liver 19 1999 183 187
9. F. Imbert-Bismut, V. Ratziu, L. Pieroni, F. Charlotte, Y. Benhamou, and T. Roynard Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study Lancet 357 2001 1069 1075
10. M. Honda, S. Kaneko, H. Kawai, Y. Shirota, and K. Kobayashi Differential gene expression between chronic hepatitis B and C hepatic lesion Gastroenterology 120 2001 955 966
11. N.A. Shackel, P.H. Mcguinness, C.A. Abbott, M.D. Gorrell, and G.W. McCaughan Insights into the pathobiology of hepatitis C virus-associated cirrhosis Am J Pathol 160 2002 641 654
12. S. Noda, S. Masumi, M. Moriyama, Y. Kannan, M. Ohta, and T. Sugano Population of hepatic macrophages and response of perfused liver to platelet-activating factor during production of thioacetamide-induced cirrhosis in rats Hepatology 24 1996 412 418
13. L. Chen, A. Goryachev, J. Sun, P. Kim, H. Zhang, and M.J. Phillips Altered expression of genes involved in hepatic morphogenesis and fibrogenesis are identified by cDNA microarray analysis in biliary atresia Hepatology 38 2003 567 576
14. M.W. Smith, Z.N. Yue, M.J. Korth, H.A. Do, L. Boix, and N. Fausto Hepatitis C virus and liver disease: global transcriptional profiling and identification of potential markers Hepatology 38 2003 1458 1467
15. H. Dashti, B. Jeppsson, I. Haggerstrand, B. Hultberg, U. Srinivas, and M. Abdulla Thioacetamide- and carbon tetrachloride-induced liver cirrhosis Eur Surg Res 21 1989 83 91
16. R.P. Tamaya Is cirrhosis of the liver experimentally produced by CCl4 an adequate model human cirrhosis? Hepatology 3 1983 112 120
17. T. Zimmermamm, A. Muller, G. Machnik, H. Franke, H. Schubert, and R. Dargel Biochemical and morphological studies on production and regression of experimental liver cirrhosis induced by thioacetamide in Uje:WIST rats Z Versuchstierkd 30 1987 165 180
18. M. Okuno, K. Akita, H. Moriwaki, N. Kawada, K. Ikeda, and K. Kaneda Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-β Gastroenterology 120 2001 1784 1800
19. M. Hashimoto, and G. Watanabe Hepatic parenchymal cell volume and the indocyanine green tolerance test J Surg Res 92 2000 222 227
20. T. Utsunomiya, Y. Hara, A. Kataoka, M. Morita, H. Arakawa, and M. Mori Cystatin-like metastasis-associated protein mRNA expression in human colorectal cancer is associated with both liver metastasis and patient survival Clin Cancer Res 8 2002 2591 2594
21. J. Schuchhardt, D. Beule, A. Malik, E. Wolski, H. Eickhoff, and H. Lehrach Normalization strategies for cDNA microarrys Nucleic Acids Res 28 2000 e47
22. T.R. Golub, D.K. Slonim, P. Tamayo, C. Huard, M. Gaasenbeek, and J.P. Mesirov Molecular classification of cancer: class discovery and class prediction by gene expression monitoring Science 286 1999 531 537
23. L.J. van't Veer, H. Dai, M.J. van de Vijver, Y.D. He, A.A.M. Hart, and M. Mao Gene expression profiling predicts clinical outcome of breast cancer Nature 415 2002 530 536
24. A. Brazma, P. Hingamp, J. Quackenbush, G. Sherlock, P. Spellman, and C. Stoeckert Mimimun information about a microarray experiment (MIAME)-toward standards for microarray data Nat Genet 29 2001 365 371
25. R.A. Blaheta, B. Kronenberger, D. Woitaschek, M.K.H. Auth, M. Scholz, and S. Weber Dedifferentiation of human hepatocytes by extracellular matrix proteins in vivo: quantitative and qualitative investigation of cytokine 7, 8, 18, 19 and vimentin filaments J Hepatol 28 1998 677 690
26. R.F. Butterworth Complications of cirrhosis III. Hepatic encephalopathy J Hepatol 32 2000 171 180
27. K. Breitkopf, B. Lahme, C.G. Tag, and A.M. Gressner Expression and matrix deposition of latent transforming growth factor b binding proteins in normal and fibrotic rat liver and transdifferentiating hepatic stellate cells in culture Hepatology 33 2001 387 396
28. G. Santelli, D. Califano, G. Chiappetta, M.T. Vento, P.C. Bartoli, and F. Zullo Thymosin-β-10 gene overexpression is a general event in human carcinogenesis Am J Pathol 155 1999 799 804
29. I. Ben-Porath, O. Yanuka, and N. Benvenisty The Tmp gene, encoding a membrane protein, is a c-Myc target with a tumorigenic activity Mol Cell Biol 19 1999 3529 3539
30. L.R. Huang, and H.C. Hsu Cloning and expression of CD24 gene in human hepatocellular carcinoma: a potential early tumor marker gene correlates with p53 mutation and tumor differentiation Cancer Res 55 1995 4717 4721
31. D.K. Hsu, C.A. Dowling, D.K.C. Jeng, J.T. Chen, R.Y. Yang, and F.T. Liu Galectin-3 expression is induced in cirrhotic liver and hepatocellular carcinoma Int J Cancer 81 1999 519 526
32. A. Okuda, M. Imagawa, Y. Maeda, M. Sakai, and M. Muramatsu Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in tha rat glutathione transferase P gene J Biol Chem 264 1989 16919 16926
33. E.M. Ellis, C.M. Slattery, and J.D. Hayes Characterization of the rat aflatoxin B1 aldehyde reductase gene, AKR7A1. Structure and chromosomal localization of AKR7A1 as well as identification of antioxidant response elements in the gene promoter Carcinogenesis 24 2003 727 737
34. G. Kaplanski, C. Farnarier, M.J. Payan, P. Bongrand, and J.M. Durand Increased levels of soluble adhesion molecules in the serum of patients with hepatitis C. Correlation with cytokine concentrations and liver inflammation and fibrosis J Hepatol 42 1997 2277 2284
35. N. Ferre, J. Camps, E. Prats, E. Vilella, A. Paul, and L. Figuera Serum paraoxonase activity: a new additional test for the improved evaluation of chronic liver damage Clin Chem 48 2002 261 268
36. Y. Levo, M. Shalit, and R. Tur-Kaspa Serum amyloid P-component as a marker of liver disease Am J Gastroenterol 77 1982 427 430
37. R.C. Horton, and J.S. Owen LCAT activity as a prognostic liver function test Lancet 336 1990 249 250
38. V.P. Kelly, E.M. Ellis, M.M. Manson, S.A. Chanas, G.J. Moffat, and R. Mclead Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver Cancer Res 60 2000 957 969
39. S. Ramaswamy, K.N. Ross, E.S. Lander, and T.R. Golub A molecular signature of metastasis in primary solid tumors Nat Genet 33 2003 49 54
40. S. Ramaswamy, and T.R. Golub DNA microarray in clinical oncology J Clin Oncol 20 2002 1932 1941
41. T. Poynard, J. McHutchison, M. Manns, C. Trepo, K. Lindsay, and Z. Goodman Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C Gastroenterology 122 2002 1303 1313