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Volumn 389, Issue , 2004, Pages 56-71

Fluorescence-based assays for RGS box function

Author keywords

[No Author keywords available]

Indexed keywords

FLUORIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN; PEPTIDE; PROTEIN SUBUNIT; RGS PROTEIN;

EID: 4344576543     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(04)89004-9     Document Type: Article
Times cited : (17)

References (29)
  • 1
    • 0030576518 scopus 로고    scopus 로고
    • GAIP and RGS4 are GTPase activating proteins for the Gi subfamily of G protein alpha subunits
    • Berman D.M., Wilkie T.M., Gilman A.G. GAIP and RGS4 are GTPase activating proteins for the Gi subfamily of G protein alpha subunits. Cell. 86:1996a;445-452
    • (1996) Cell , vol.86 , pp. 445-452
    • Berman, D.M.1    Wilkie, T.M.2    Gilman, A.G.3
  • 2
    • 0029861417 scopus 로고    scopus 로고
    • The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis
    • Berman D.M., Kozasa T., Gilman A.G. The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis. J. Biol. Chem. 271:1996;27209-27212
    • (1996) J. Biol. Chem. , vol.271 , pp. 27209-27212
    • Berman, D.M.1    Kozasa, T.2    Gilman, A.G.3
  • 3
    • 0042697152 scopus 로고    scopus 로고
    • Mechanistic considerations in high throughput screening
    • Copeland R.A. Mechanistic considerations in high throughput screening. Anal. Biochem. 320:2003;1-12
    • (2003) Anal. Biochem. , vol.320 , pp. 1-12
    • Copeland, R.A.1
  • 6
    • 0028884014 scopus 로고
    • Fluorescence resonance energy transfer spectroscopy is a reliable "ruler" for measuring structural changes in proteins. Dispelling the problem of the unknown orientation factor
    • dos Remedios C.G., Moens P.D. Fluorescence resonance energy transfer spectroscopy is a reliable "ruler" for measuring structural changes in proteins. Dispelling the problem of the unknown orientation factor. J. Struct. Biol. 115:1995;175-185
    • (1995) J. Struct. Biol. , vol.115 , pp. 175-185
    • Dos Remedios, C.G.1    Moens, P.D.2
  • 7
    • 0030725498 scopus 로고    scopus 로고
    • Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins
    • Druey K.M., Kehrl J.H. Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins. Proc. Natl. Acad. Sci. USA. 94:1997;12851-12856
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12851-12856
    • Druey, K.M.1    Kehrl, J.H.2
  • 8
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • Gilman A.G. G proteins: Transducers of receptor-generated signals. Annu. Rev. Biochem. 56:1987;615-649
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 9
    • 0034710922 scopus 로고    scopus 로고
    • Molecular spectroscopy and dynamics of intrinsically fluorescent proteins: Coral red (dsRed) and yellow (Citrine)
    • Heikal A.A., Hess S.T., Baird G.S., Tsien R.Y., Webb W.W. Molecular spectroscopy and dynamics of intrinsically fluorescent proteins: Coral red (dsRed) and yellow (Citrine). Proc. Natl. Acad. Sci. USA. 97:2000;11996-12001
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 11996-12001
    • Heikal, A.A.1    Hess, S.T.2    Baird, G.S.3    Tsien, R.Y.4    Webb, W.W.5
  • 10
    • 0023096422 scopus 로고
    • The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide binding regulatory proteins
    • Higashijima T., Ferguson K.M., Sternweis P.C., Ross E.M., Smigel M.D., Gilman A.G. The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide binding regulatory proteins. J. Biol. Chem. 262:1987;752-756
    • (1987) J. Biol. Chem. , vol.262 , pp. 752-756
    • Higashijima, T.1    Ferguson, K.M.2    Sternweis, P.C.3    Ross, E.M.4    Smigel, M.D.5    Gilman, A.G.6
  • 11
    • 0002838823 scopus 로고    scopus 로고
    • The GoLoco Motif: Heralding a new tango between G protein signaling and cell division
    • Kimple R.J., Willard F.S., Siderovski D.P. The GoLoco Motif: Heralding a new tango between G protein signaling and cell division. Mol. Intervent. 2:2002a;88-100
    • (2002) Mol. Intervent. , vol.2 , pp. 88-100
    • Kimple, R.J.1    Willard, F.S.2    Siderovski, D.P.3
  • 12
    • 0037171778 scopus 로고    scopus 로고
    • Structural determinants for GoLoco induced inhibition of nucleotide release by G-alpha subunits
    • Kimple R.J., Kimple M.E., Betts L., Sondek J., Siderovski D.P. Structural determinants for GoLoco induced inhibition of nucleotide release by G-alpha subunits. Nature. 416:2002b;878-881
    • (2002) Nature , vol.416 , pp. 878-881
    • Kimple, R.J.1    Kimple, M.E.2    Betts, L.3    Sondek, J.4    Siderovski, D.P.5
  • 13
    • 0035800830 scopus 로고    scopus 로고
    • RGS12 and RGS14 GoLoco motifs are G-alpha(i) interaction sites with guanine nucleotide dissociation inhibitor activity
    • Kimple R.J., De Vries L., Tronchere H., Behe C.I., Morris R.A., Gist Farquhar M., Siderovski D.P. RGS12 and RGS14 GoLoco motifs are G-alpha(i) interaction sites with guanine nucleotide dissociation inhibitor activity. J. Biol. Chem. 276:2001;29275-29281
    • (2001) J. Biol. Chem. , vol.276 , pp. 29275-29281
    • Kimple, R.J.1    De Vries, L.2    Tronchere, H.3    Behe, C.I.4    Morris, R.A.5    Gist Farquhar, M.6    Siderovski, D.P.7
  • 14
    • 0037609481 scopus 로고    scopus 로고
    • Established and emerging fluorescence based assays for G-protein function: Heterotrimeric G-protein-alpha subunits and regulator of G protein signaling (RGS) proteins
    • Kimple R.J., Jones M.B., Shutes A., Yerxa B.R., Siderovski D.P., Willard F.S. Established and emerging fluorescence based assays for G-protein function: Heterotrimeric G-protein-alpha subunits and regulator of G protein signaling (RGS) proteins. Comb. Chem. High Throughput Screen. 6:2003;399-407
    • (2003) Comb. Chem. High Throughput Screen. , vol.6 , pp. 399-407
    • Kimple, R.J.1    Jones, M.B.2    Shutes, A.3    Yerxa, B.R.4    Siderovski, D.P.5    Willard, F.S.6
  • 15
    • 4344688240 scopus 로고    scopus 로고
    • Purification and in vitro functional analyses of R6S12 and RGS14 GoLoco-motif peptides
    • Kimple R.J., Willard F.S., Siderovski D.P. Purification and in vitro functional analyses of R6S12 and RGS14 GoLoco-motif peptides. Methods Enzymol. 390:(26):2004;419-436
    • (2004) Methods Enzymol. , vol.390 , Issue.26 , pp. 419-436
    • Kimple, R.J.1    Willard, F.S.2    Siderovski, D.P.3
  • 18
    • 0034721832 scopus 로고    scopus 로고
    • Rapid kinetics of regulator of G-protein signaling (RGS)-mediated Galphai and Galphao deactivation. Galpha specificity of RGS4 and RGS7
    • Lan K.L., Zhong H., Nanamori M., Neubig R.R. Rapid kinetics of regulator of G-protein signaling (RGS)-mediated Galphai and Galphao deactivation. Galpha specificity of RGS4 and RGS7. J. Biol. Chem. 275:2000;33497-33503
    • (2000) J. Biol. Chem. , vol.275 , pp. 33497-33503
    • Lan, K.L.1    Zhong, H.2    Nanamori, M.3    Neubig, R.R.4
  • 19
    • 0034581516 scopus 로고    scopus 로고
    • Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein
    • Miyawaki A., Tsien R.Y. Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein. Methods Enzymol. 327:2000;472-500
    • (2000) Methods Enzymol. , vol.327 , pp. 472-500
    • Miyawaki, A.1    Tsien, R.Y.2
  • 20
    • 0033578385 scopus 로고    scopus 로고
    • Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins
    • Mukhopadhyay S., Ross E.M. Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins. Proc. Natl. Acad. Sci. USA. 96:1999;9539-9544
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9539-9544
    • Mukhopadhyay, S.1    Ross, E.M.2
  • 21
    • 0036490096 scopus 로고    scopus 로고
    • Regulators of G-protein signalling as new central nervous system drug targets
    • Neubig R.R., Siderovski D.P. Regulators of G-protein signalling as new central nervous system drug targets. Nature Rev. Drug Discov. 1:2002;187-197
    • (2002) Nature Rev. Drug Discov. , vol.1 , pp. 187-197
    • Neubig, R.R.1    Siderovski, D.P.2
  • 23
    • 0030738476 scopus 로고    scopus 로고
    • The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro
    • Popov S., Yu K., Kozasa T., Wilkie T.M. The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro. Proc. Natl. Acad. Sci. USA. 94:1997;7216-7220
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7216-7220
    • Popov, S.1    Yu, K.2    Kozasa, T.3    Wilkie, T.M.4
  • 26
    • 0030982264 scopus 로고    scopus 로고
    • Structure of RGS4 bound to AlF4-activated G(i alpha1): Stabilization of the transition state for GTP hydrolysis
    • Tesmer J.J., Berman D.M., Gilman A.G., Sprang S.R. Structure of RGS4 bound to AlF4-activated G(i alpha1): Stabilization of the transition state for GTP hydrolysis. Cell. 89:1997;251-261
    • (1997) Cell , vol.89 , pp. 251-261
    • Tesmer, J.J.1    Berman, D.M.2    Gilman, A.G.3    Sprang, S.R.4
  • 28
    • 84862394566 scopus 로고    scopus 로고
    • "Toward small molecule inhibitors of RGS proteins: Development of computational and in vitro fluorescence-based approaches"
    • A 219 (abstract 165.4)
    • Willard F.S., Kimple A.J., Kimple R.J., Siderovski D.P. "Toward small molecule inhibitors of RGS proteins: Development of computational and in vitro fluorescence-based approaches." FASEB J. 18:(4):2004a;. A 219 (abstract 165.4)
    • (2004) FASEB J. , vol.18 , Issue.4
    • Willard, F.S.1    Kimple, A.J.2    Kimple, R.J.3    Siderovski, D.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.