-
1
-
-
0030576518
-
GAIP and RGS4 are GTPase activating proteins for the Gi subfamily of G protein alpha subunits
-
Berman D.M., Wilkie T.M., Gilman A.G. GAIP and RGS4 are GTPase activating proteins for the Gi subfamily of G protein alpha subunits. Cell. 86:1996a;445-452
-
(1996)
Cell
, vol.86
, pp. 445-452
-
-
Berman, D.M.1
Wilkie, T.M.2
Gilman, A.G.3
-
2
-
-
0029861417
-
The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis
-
Berman D.M., Kozasa T., Gilman A.G. The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis. J. Biol. Chem. 271:1996;27209-27212
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27209-27212
-
-
Berman, D.M.1
Kozasa, T.2
Gilman, A.G.3
-
3
-
-
0042697152
-
Mechanistic considerations in high throughput screening
-
Copeland R.A. Mechanistic considerations in high throughput screening. Anal. Biochem. 320:2003;1-12
-
(2003)
Anal. Biochem.
, vol.320
, pp. 1-12
-
-
Copeland, R.A.1
-
4
-
-
0034687771
-
Activator of G protein signaling 3 is a guanine dissociation inhibitor for G-alpha i subunits
-
De Vries L., Fischer T., Tronchere H., Brothers G.M., Strockbine B., Siderovski D.P., Farquhar M.G. Activator of G protein signaling 3 is a guanine dissociation inhibitor for G-alpha i subunits. Proc. Natl. Acad. Sci. USA. 97:2000;14364-14369
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14364-14369
-
-
De Vries, L.1
Fischer, T.2
Tronchere, H.3
Brothers, G.M.4
Strockbine, B.5
Siderovski, D.P.6
Farquhar, M.G.7
-
5
-
-
0032489381
-
Selective uncoupling of RGS action by a single point mutation in the G protein alpha-subunit
-
DiBello P.R., Garrison T.R., Apanovitch D.M., Hoffman G., Shuey D.J., Mason K., Cockett M.I., Dohlman H.G. Selective uncoupling of RGS action by a single point mutation in the G protein alpha-subunit. J. Biol. Chem. 273:1998;5780-5784
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5780-5784
-
-
Dibello, P.R.1
Garrison, T.R.2
Apanovitch, D.M.3
Hoffman, G.4
Shuey, D.J.5
Mason, K.6
Cockett, M.I.7
Dohlman, H.G.8
-
6
-
-
0028884014
-
Fluorescence resonance energy transfer spectroscopy is a reliable "ruler" for measuring structural changes in proteins. Dispelling the problem of the unknown orientation factor
-
dos Remedios C.G., Moens P.D. Fluorescence resonance energy transfer spectroscopy is a reliable "ruler" for measuring structural changes in proteins. Dispelling the problem of the unknown orientation factor. J. Struct. Biol. 115:1995;175-185
-
(1995)
J. Struct. Biol.
, vol.115
, pp. 175-185
-
-
Dos Remedios, C.G.1
Moens, P.D.2
-
7
-
-
0030725498
-
Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins
-
Druey K.M., Kehrl J.H. Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins. Proc. Natl. Acad. Sci. USA. 94:1997;12851-12856
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12851-12856
-
-
Druey, K.M.1
Kehrl, J.H.2
-
8
-
-
0023062991
-
G proteins: Transducers of receptor-generated signals
-
Gilman A.G. G proteins: Transducers of receptor-generated signals. Annu. Rev. Biochem. 56:1987;615-649
-
(1987)
Annu. Rev. Biochem.
, vol.56
, pp. 615-649
-
-
Gilman, A.G.1
-
9
-
-
0034710922
-
Molecular spectroscopy and dynamics of intrinsically fluorescent proteins: Coral red (dsRed) and yellow (Citrine)
-
Heikal A.A., Hess S.T., Baird G.S., Tsien R.Y., Webb W.W. Molecular spectroscopy and dynamics of intrinsically fluorescent proteins: Coral red (dsRed) and yellow (Citrine). Proc. Natl. Acad. Sci. USA. 97:2000;11996-12001
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11996-12001
-
-
Heikal, A.A.1
Hess, S.T.2
Baird, G.S.3
Tsien, R.Y.4
Webb, W.W.5
-
10
-
-
0023096422
-
The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide binding regulatory proteins
-
Higashijima T., Ferguson K.M., Sternweis P.C., Ross E.M., Smigel M.D., Gilman A.G. The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide binding regulatory proteins. J. Biol. Chem. 262:1987;752-756
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 752-756
-
-
Higashijima, T.1
Ferguson, K.M.2
Sternweis, P.C.3
Ross, E.M.4
Smigel, M.D.5
Gilman, A.G.6
-
11
-
-
0002838823
-
The GoLoco Motif: Heralding a new tango between G protein signaling and cell division
-
Kimple R.J., Willard F.S., Siderovski D.P. The GoLoco Motif: Heralding a new tango between G protein signaling and cell division. Mol. Intervent. 2:2002a;88-100
-
(2002)
Mol. Intervent.
, vol.2
, pp. 88-100
-
-
Kimple, R.J.1
Willard, F.S.2
Siderovski, D.P.3
-
12
-
-
0037171778
-
Structural determinants for GoLoco induced inhibition of nucleotide release by G-alpha subunits
-
Kimple R.J., Kimple M.E., Betts L., Sondek J., Siderovski D.P. Structural determinants for GoLoco induced inhibition of nucleotide release by G-alpha subunits. Nature. 416:2002b;878-881
-
(2002)
Nature
, vol.416
, pp. 878-881
-
-
Kimple, R.J.1
Kimple, M.E.2
Betts, L.3
Sondek, J.4
Siderovski, D.P.5
-
13
-
-
0035800830
-
RGS12 and RGS14 GoLoco motifs are G-alpha(i) interaction sites with guanine nucleotide dissociation inhibitor activity
-
Kimple R.J., De Vries L., Tronchere H., Behe C.I., Morris R.A., Gist Farquhar M., Siderovski D.P. RGS12 and RGS14 GoLoco motifs are G-alpha(i) interaction sites with guanine nucleotide dissociation inhibitor activity. J. Biol. Chem. 276:2001;29275-29281
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29275-29281
-
-
Kimple, R.J.1
De Vries, L.2
Tronchere, H.3
Behe, C.I.4
Morris, R.A.5
Gist Farquhar, M.6
Siderovski, D.P.7
-
14
-
-
0037609481
-
Established and emerging fluorescence based assays for G-protein function: Heterotrimeric G-protein-alpha subunits and regulator of G protein signaling (RGS) proteins
-
Kimple R.J., Jones M.B., Shutes A., Yerxa B.R., Siderovski D.P., Willard F.S. Established and emerging fluorescence based assays for G-protein function: Heterotrimeric G-protein-alpha subunits and regulator of G protein signaling (RGS) proteins. Comb. Chem. High Throughput Screen. 6:2003;399-407
-
(2003)
Comb. Chem. High Throughput Screen.
, vol.6
, pp. 399-407
-
-
Kimple, R.J.1
Jones, M.B.2
Shutes, A.3
Yerxa, B.R.4
Siderovski, D.P.5
Willard, F.S.6
-
15
-
-
4344688240
-
Purification and in vitro functional analyses of R6S12 and RGS14 GoLoco-motif peptides
-
Kimple R.J., Willard F.S., Siderovski D.P. Purification and in vitro functional analyses of R6S12 and RGS14 GoLoco-motif peptides. Methods Enzymol. 390:(26):2004;419-436
-
(2004)
Methods Enzymol.
, vol.390
, Issue.26
, pp. 419-436
-
-
Kimple, R.J.1
Willard, F.S.2
Siderovski, D.P.3
-
17
-
-
0032557248
-
A point mutation in Galphao and Galphail blocks interaction with regulator of G protein signaling proteins
-
Lan K.L., Sarvazyan N.A., Taussig R., Mackenzie R.G., DiBello P.R., Dohlman H.G., Neubig R.R. A point mutation in Galphao and Galphail blocks interaction with regulator of G protein signaling proteins. J. Biol. Chem. 273:1998;12794-12797
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12794-12797
-
-
Lan, K.L.1
Sarvazyan, N.A.2
Taussig, R.3
MacKenzie, R.G.4
Dibello, P.R.5
Dohlman, H.G.6
Neubig, R.R.7
-
18
-
-
0034721832
-
Rapid kinetics of regulator of G-protein signaling (RGS)-mediated Galphai and Galphao deactivation. Galpha specificity of RGS4 and RGS7
-
Lan K.L., Zhong H., Nanamori M., Neubig R.R. Rapid kinetics of regulator of G-protein signaling (RGS)-mediated Galphai and Galphao deactivation. Galpha specificity of RGS4 and RGS7. J. Biol. Chem. 275:2000;33497-33503
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33497-33503
-
-
Lan, K.L.1
Zhong, H.2
Nanamori, M.3
Neubig, R.R.4
-
19
-
-
0034581516
-
Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein
-
Miyawaki A., Tsien R.Y. Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein. Methods Enzymol. 327:2000;472-500
-
(2000)
Methods Enzymol.
, vol.327
, pp. 472-500
-
-
Miyawaki, A.1
Tsien, R.Y.2
-
20
-
-
0033578385
-
Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins
-
Mukhopadhyay S., Ross E.M. Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins. Proc. Natl. Acad. Sci. USA. 96:1999;9539-9544
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9539-9544
-
-
Mukhopadhyay, S.1
Ross, E.M.2
-
21
-
-
0036490096
-
Regulators of G-protein signalling as new central nervous system drug targets
-
Neubig R.R., Siderovski D.P. Regulators of G-protein signalling as new central nervous system drug targets. Nature Rev. Drug Discov. 1:2002;187-197
-
(2002)
Nature Rev. Drug Discov.
, vol.1
, pp. 187-197
-
-
Neubig, R.R.1
Siderovski, D.P.2
-
23
-
-
0030738476
-
The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro
-
Popov S., Yu K., Kozasa T., Wilkie T.M. The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro. Proc. Natl. Acad. Sci. USA. 94:1997;7216-7220
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7216-7220
-
-
Popov, S.1
Yu, K.2
Kozasa, T.3
Wilkie, T.M.4
-
24
-
-
0026578325
-
Primary structure of the Aequorea victoria green-fluorescent protein
-
Prasher D.C., Eckenrode V.K., Ward W.W., Prendergast F.G., Cormier M.J. Primary structure of the Aequorea victoria green-fluorescent protein. Gene. 111:1992;229-233
-
(1992)
Gene
, vol.111
, pp. 229-233
-
-
Prasher, D.C.1
Eckenrode, V.K.2
Ward, W.W.3
Prendergast, F.G.4
Cormier, M.J.5
-
26
-
-
0030982264
-
Structure of RGS4 bound to AlF4-activated G(i alpha1): Stabilization of the transition state for GTP hydrolysis
-
Tesmer J.J., Berman D.M., Gilman A.G., Sprang S.R. Structure of RGS4 bound to AlF4-activated G(i alpha1): Stabilization of the transition state for GTP hydrolysis. Cell. 89:1997;251-261
-
(1997)
Cell
, vol.89
, pp. 251-261
-
-
Tesmer, J.J.1
Berman, D.M.2
Gilman, A.G.3
Sprang, S.R.4
-
28
-
-
84862394566
-
"Toward small molecule inhibitors of RGS proteins: Development of computational and in vitro fluorescence-based approaches"
-
A 219 (abstract 165.4)
-
Willard F.S., Kimple A.J., Kimple R.J., Siderovski D.P. "Toward small molecule inhibitors of RGS proteins: Development of computational and in vitro fluorescence-based approaches." FASEB J. 18:(4):2004a;. A 219 (abstract 165.4)
-
(2004)
FASEB J.
, vol.18
, Issue.4
-
-
Willard, F.S.1
Kimple, A.J.2
Kimple, R.J.3
Siderovski, D.P.4
|