-
1
-
-
0028910316
-
Over-expression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor
-
Alexandrow, M. G., M. Kawabata, M. Aakre, and H. L. Moses. 1995. Over-expression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor. Proc. Natl. Acad. Sci. USA 92:3239-3243.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3239-3243
-
-
Alexandrow, M.G.1
Kawabata, M.2
Aakre, M.3
Moses, H.L.4
-
2
-
-
0029147732
-
Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase
-
Aprelikova, O., Y. Xiong, and E. T. Liu. 1995. Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. J. Biol. Chem. 270: 18195-18197.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18195-18197
-
-
Aprelikova, O.1
Xiong, Y.2
Liu, E.T.3
-
3
-
-
0029670606
-
Characterization of p21(Cip1/ Waf1) peptide domains required for cyclin E/cdk2 and PCNA interaction
-
Chen, I. T., M. Akamatsu, M. L. Smith, F. D. T. Lung, D. Duba, P. P. Roller, A. J. Fornace, and P. M. O'Connor. 1996. Characterization of p21(Cip1/ Waf1) peptide domains required for cyclin E/cdk2 and PCNA interaction. Oncogene 12:595-607.
-
(1996)
Oncogene
, vol.12
, pp. 595-607
-
-
Chen, I.T.1
Akamatsu, M.2
Smith, M.L.3
Lung, F.D.T.4
Duba, D.5
Roller, P.P.6
Fornace, A.J.7
O'Connor, P.M.8
-
4
-
-
0028899480
-
Separate domains of p21 involved in the inhibition of cdk kinase and PCNA
-
Chen, J., P. K. Jackson, M. W. Kirschner, and A. Dutta. 1995. Separate domains of p21 involved in the inhibition of cdk kinase and PCNA. Nature 374:386-388.
-
(1995)
Nature
, vol.374
, pp. 386-388
-
-
Chen, J.1
Jackson, P.K.2
Kirschner, M.W.3
Dutta, A.4
-
6
-
-
0028978183
-
Mice lacking p21(cip1/waf1) undergo normal development, but are defective in G1 checkpoint control
-
Deng, C. X., P. M. Zhang, J. W. Harper, S. J. Elledge, and P. Leder. 1995. Mice lacking p21(cip1/waf1) undergo normal development, but are defective in G1 checkpoint control. Cell 82:675-684.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.X.1
Zhang, P.M.2
Harper, J.W.3
Elledge, S.J.4
Leder, P.5
-
7
-
-
0026698263
-
Association of human cyclin e with periodic G1-S phase protein kinase
-
Dulic, V., E. Lees, and S. Reed. 1992. Association of human cyclin E with periodic G1-S phase protein kinase. Science 257:1958-1961.
-
(1992)
Science
, vol.257
, pp. 1958-1961
-
-
Dulic, V.1
Lees, E.2
Reed, S.3
-
8
-
-
0028294605
-
Waf1/CIP1 is induced in p53-mediated g(1) arrest and apoptosis
-
el Deiry, W. S., J. W. Harper, P. M. O'Connor, V. E. Velculescu, C. E. Canman, J. Jackman, J. A. Pietenpol, M. Burrell, D. E. Hill, Y. S. Wang, et al. 1994, Waf1/CIP1 is induced in p53-mediated g(1) arrest and apoptosis. Cancer Res. 54:1169-1174.
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
El Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wang, Y.S.10
-
9
-
-
0029808466
-
Cell cycle checkpoints: Preventing an identity crisis
-
Elledge, S. J. 1996. Cell cycle checkpoints: preventing an identity crisis. Science 274:1664-1672.
-
(1996)
Science
, vol.274
, pp. 1664-1672
-
-
Elledge, S.J.1
-
10
-
-
0020961333
-
Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division
-
Evans, T., E. T. Rosenthal, J. Youngblom, D. Distel, and T. Hunt. 1983. Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 33:389-396.
-
(1983)
Cell
, vol.33
, pp. 389-396
-
-
Evans, T.1
Rosenthal, E.T.2
Youngblom, J.3
Distel, D.4
Hunt, T.5
-
11
-
-
0026319225
-
Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins
-
Galaktionov, K., and D. Beach. 1991. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. Cell 67:1181-1194.
-
(1991)
Cell
, vol.67
, pp. 1181-1194
-
-
Galaktionov, K.1
Beach, D.2
-
12
-
-
0029779280
-
Cdc25a cell-cycle phosphatase as a target of c-myc
-
Galaktionov, K., X. Chen, and D. Beach. 1996. Cdc25A cell-cycle phosphatase as a target of c-myc. Nature 382:511-517.
-
(1996)
Nature
, vol.382
, pp. 511-517
-
-
Galaktionov, K.1
Chen, X.2
Beach, D.3
-
13
-
-
0029119560
-
CDC25 phosphatase as potential human oncogene
-
Galaktionov, K., A. Lee, J. Eckstein, G. Draetta, J. Meckler, M. Loda, and D. Beach. 1996. CDC25 phosphatase as potential human oncogene. Science 269:1575-1577.
-
(1996)
Science
, vol.269
, pp. 1575-1577
-
-
Galaktionov, K.1
Lee, A.2
Eckstein, J.3
Draetta, G.4
Meckler, J.5
Loda, M.6
Beach, D.7
-
14
-
-
0026713875
-
Cell cycle regulation of CDK2 activity by phosphorylation of Thr 160 and Tyr15
-
Gu, Y., J. Rosenblatt, and D. O. Morgan. 1992. Cell cycle regulation of CDK2 activity by phosphorylation of Thr 160 and Tyr15. EMBO J. 11:3995-4005.
-
(1992)
EMBO J.
, vol.11
, pp. 3995-4005
-
-
Gu, Y.1
Rosenblatt, J.2
Morgan, D.O.3
-
15
-
-
0027142956
-
Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins
-
Hanoon, G. J., D. Demetrick, and D. Beach. 1993. Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes Dev. 7:2378-2391.
-
(1993)
Genes Dev.
, vol.7
, pp. 2378-2391
-
-
Hanoon, G.J.1
Demetrick, D.2
Beach, D.3
-
16
-
-
0028866121
-
Abrogation of p53-induced cell cycle arrest by c-Myc: Evidence for an inhibitor of p21-WAF1/CIP1/SDI1
-
Hermeking, H., J. O. Funk, M. Reichert, J. W. Rllwart, and D. Kick. 1995. Abrogation of p53-induced cell cycle arrest by c-Myc: evidence for an inhibitor of p21-WAF1/CIP1/SDI1. Oncogene 11:1409-1415.
-
(1995)
Oncogene
, vol.11
, pp. 1409-1415
-
-
Hermeking, H.1
Funk, J.O.2
Reichert, M.3
Rllwart, J.W.4
Kick, D.5
-
17
-
-
0027509501
-
Phosphorylation and activation of human cdc25C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis
-
Hoffmann, I., P. Clarke, M. Marcote, E. Karsenti, and G. Draetta. 1993. Phosphorylation and activation of human cdc25C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J. 12:53-63.
-
(1993)
EMBO J.
, vol.12
, pp. 53-63
-
-
Hoffmann, I.1
Clarke, P.2
Marcote, M.3
Karsenti, E.4
Draetta, G.5
-
18
-
-
0028022034
-
Activation of the phosphatase activity of human cdc25a by a cdc2-cyclin e dependent phosphorylation at the G1-S transition
-
Hoffmann, I., G. Draetta, and E. Karsenti. 1994. Activation of the phosphatase activity of human cdc25A by a cdc2-cyclin E dependent phosphorylation at the G1-S transition. EMBO J. 13:4302-4310.
-
(1994)
EMBO J.
, vol.13
, pp. 4302-4310
-
-
Hoffmann, I.1
Draetta, G.2
Karsenti, E.3
-
19
-
-
0028314952
-
cdc25a is a novel phosphatase functioning early in the cell cycle
-
Jinno, S., K. Suto, A. Nagata, et al. 1994. cdc25A is a novel phosphatase functioning early in the cell cycle. EMBO J. 13:1549-1556.
-
(1994)
EMBO J.
, vol.13
, pp. 1549-1556
-
-
Jinno, S.1
Suto, K.2
Nagata, A.3
-
20
-
-
0029807944
-
How proteolysis drives the cell cycle
-
King, R. W., R. J. Deshaies, J. M. Peters, and M. W. Kirschner. 1996. How proteolysis drives the cell cycle. Science 274:1652-1659.
-
(1996)
Science
, vol.274
, pp. 1652-1659
-
-
King, R.W.1
Deshaies, R.J.2
Peters, J.M.3
Kirschner, M.W.4
-
21
-
-
0029559027
-
Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase check-point
-
Krek, W., G. Xu, and D. M. Livingsrone. 1995. Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase check-point. Cell 83:1149-1158.
-
(1995)
Cell
, vol.83
, pp. 1149-1158
-
-
Krek, W.1
Xu, G.2
Livingsrone, D.M.3
-
22
-
-
0029950859
-
Loss of transactivation and transrepression function, and not RPA binding, alters growth suppression by p53
-
Leiter, L. M., J. Chen, T. Marathe, M. Tanaka, and A. Dutta. 1996. Loss of transactivation and transrepression function, and not RPA binding, alters growth suppression by p53. Oncogene 12:2661-2668.
-
(1996)
Oncogene
, vol.12
, pp. 2661-2668
-
-
Leiter, L.M.1
Chen, J.2
Marathe, T.3
Tanaka, M.4
Dutta, A.5
-
23
-
-
0028074603
-
Differential effects by the p21 cdk inhibitor on PCNA-dependent DNA replication and repair
-
Li, R., S. Waga, G. J. Hannon, D. Beach, and B. Stillman. 1994. Differential effects by the p21 cdk inhibitor on PCNA-dependent DNA replication and repair. Nature 371:534-537.
-
(1994)
Nature
, vol.371
, pp. 534-537
-
-
Li, R.1
Waga, S.2
Hannon, G.J.3
Beach, D.4
Stillman, B.5
-
24
-
-
0027135209
-
The adenovirus E1A-associated 130 kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E
-
Li, Y., C. Graham, S. Lacy, A. M. V. Duncan, and P. Whyte. 1993. The adenovirus E1A-associated 130 kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes Dev. 7:2366-2377.
-
(1993)
Genes Dev.
, vol.7
, pp. 2366-2377
-
-
Li, Y.1
Graham, C.2
Lacy, S.3
Duncan, A.M.V.4
Whyte, P.5
-
26
-
-
0029063745
-
Cell-cycle inhibition by independent cdk and PCNA binding domains in p21-CIP1
-
Luo, Y., J. Hurwitz, and J. Massague. 1995. Cell-cycle inhibition by independent cdk and PCNA binding domains in p21-CIP1. Nature 375:159-161.
-
(1995)
Nature
, vol.375
, pp. 159-161
-
-
Luo, Y.1
Hurwitz, J.2
Massague, J.3
-
27
-
-
0029257493
-
Evidence that SH2 domains promote processive phosphorylation by protein tyrosine kinase
-
Mayer, B. J., H. Hirai, and R. Sakai. 1995. Evidence that SH2 domains promote processive phosphorylation by protein tyrosine kinase. Curr. Biol. 5:296-305.
-
(1995)
Curr. Biol.
, vol.5
, pp. 296-305
-
-
Mayer, B.J.1
Hirai, H.2
Sakai, R.3
-
28
-
-
0025987535
-
p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast
-
Millar, J. B., C. H. McGowan, G. Lenaers, R. Jones, and P. Russel. 1991. p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. EMBO J. 10:4301-4309.
-
(1991)
EMBO J.
, vol.10
, pp. 4301-4309
-
-
Millar, J.B.1
McGowan, C.H.2
Lenaers, G.3
Jones, R.4
Russel, P.5
-
29
-
-
0028931265
-
Principles of CDK regulation
-
Morgan, D. O. 1995. Principles of CDK regulation. Nature 374:131-134.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
30
-
-
0026234297
-
An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells
-
Nagata, A., M. Igarashi, S. Jinno, S. K., and H. Okayama. 1991. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. New Biol. 3:959-967.
-
(1991)
New Biol.
, vol.3
, pp. 959-967
-
-
Nagata, A.1
Igarashi, M.2
Jinno, S.3
K., S.4
Okayama, H.5
-
31
-
-
0029807526
-
Viewpoint: Putting the cell cycle in order
-
Nasmyth, K. 1996. Viewpoint: putting the cell cycle in order. Science 274: 1643-1645.
-
(1996)
Science
, vol.274
, pp. 1643-1645
-
-
Nasmyth, K.1
-
32
-
-
0027193034
-
Cyclin-dependent regulation of G1 in mammalian fibroblast
-
Ohtsubo, M., and J. M. Roberts. 1993. Cyclin-dependent regulation of G1 in mammalian fibroblast. Science 259:1908-1912.
-
(1993)
Science
, vol.259
, pp. 1908-1912
-
-
Ohtsubo, M.1
Roberts, J.M.2
-
33
-
-
0029665852
-
Crystal structure of the p27(Kip1) cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
-
Russo, A. A., P. D. Jeffry, A. K. Patten, J. Massague, and N. P. Pavletich. 1996. Crystal structure of the p27(Kip1) cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature 382:325-331.
-
(1996)
Nature
, vol.382
, pp. 325-331
-
-
Russo, A.A.1
Jeffry, P.D.2
Patten, A.K.3
Massague, J.4
Pavletich, N.P.5
-
34
-
-
0025324692
-
Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2
-
Sandhu, K., S. I. Reed, H. Richardson, and P. Russell. 1990. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2. Proc. Natl. Acad. Sci. USA 87:5139-5143.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5139-5143
-
-
Sandhu, K.1
Reed, S.I.2
Richardson, H.3
Russell, P.4
-
35
-
-
0029849620
-
Cancer cell cycle
-
Sherr, J. 1996. Cancer cell cycle. Science 274:1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, J.1
-
36
-
-
0028675510
-
Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair
-
Shivji, M. K., S. T. Grey, U. P. Strausfeld, R. D. Wood, and J. J. Blow. 1994. Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair. Curr. Biol. 4:1062-1068.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1062-1068
-
-
Shivji, M.K.1
Grey, S.T.2
Strausfeld, U.P.3
Wood, R.D.4
Blow, J.J.5
-
39
-
-
0029094329
-
Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes
-
Steiner, P., A. Philipp, J. Lukas, D. Godden-Kent, M. Pagano, S. Mittnacht, J. Bartek, and M. Eilers. 1995. Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes. EMBO J. 14:4814-4826.
-
(1995)
EMBO J.
, vol.14
, pp. 4814-4826
-
-
Steiner, P.1
Philipp, A.2
Lukas, J.3
Godden-Kent, D.4
Pagano, M.5
Mittnacht, S.6
Bartek, J.7
Eilers, M.8
-
40
-
-
0029810269
-
Cell cycle control of DNA replication
-
Stillman, B. 1996. Cell cycle control of DNA replication. Science 274:1659-1664.
-
(1996)
Science
, vol.274
, pp. 1659-1664
-
-
Stillman, B.1
-
41
-
-
0028518750
-
Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases
-
Strausfeld, U. P., M. Howell, R. Rempel, J. L. Maller, T. Hunt, and J. J. Blow. 1994. Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. Curr. Biol. 4:876-883.
-
(1994)
Curr. Biol.
, vol.4
, pp. 876-883
-
-
Strausfeld, U.P.1
Howell, M.2
Rempel, R.3
Maller, J.L.4
Hunt, T.5
Blow, J.J.6
-
42
-
-
0029014496
-
Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation
-
Terada, Y., M. Tatsuka, S. Jinno, and H. Okayama. 1995. Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation. Nature 376:358-362.
-
(1995)
Nature
, vol.376
, pp. 358-362
-
-
Terada, Y.1
Tatsuka, M.2
Jinno, S.3
Okayama, H.4
-
43
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
Waga, S., G. J. Hannon, D. Beach, and B. Stillman. 1994. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369:574-578.
-
(1994)
Nature
, vol.369
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
44
-
-
0027482633
-
Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25
-
Zheng, X. F., and J. V. Ruderman. 1993. Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25. Cell 75:155-164.
-
(1993)
Cell
, vol.75
, pp. 155-164
-
-
Zheng, X.F.1
Ruderman, J.V.2
-
45
-
-
0028983384
-
p107 uses a p21-related domain to bind cyclin/cdk2 and regulate interactions with E2F
-
Zhu, L., E. Harlow, and B. D. Dynlacht. 1995. p107 uses a p21-related domain to bind cyclin/cdk2 and regulate interactions with E2F. Genes Dev. 9:1740-1752.
-
(1995)
Genes Dev.
, vol.9
, pp. 1740-1752
-
-
Zhu, L.1
Harlow, E.2
Dynlacht, B.D.3
|