On the modeling of snake venom serine proteinase interactions with benzamidine-based thrombin inhibitors

Protein Science

Volumn 13, Issue 9, 2004, Pages 2355-2369

  Henriques, Elsa S ^a   Fonseca, Nelson ^a   Ramos, Maria João ^a  

^a UNIVERSITY OF PORTO   (Portugal)

Author keywords

Benzamidine based inhibitors; Homology modeling; Thrombin; Venom serine proteinase

Indexed keywords

BENZAMIDINE DERIVATIVE; FIBRINOGEN; KALLIKREIN; KININ; NALPHA (2 NAPHTHYLSULFONYLGLYCYL) 4 AMIDINOPHENYLALANINE; NALPHA TOSYL 3 AMIDINOPHENYLALANINE PIPERIDINE; NALPHA TOSYL 4 AMIDINOPHENYLALANINE PIPERIDINE; PLASMINOGEN ACTIVATOR; SERINE PROTEINASE; SNAKE VENOM; THROMBIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG PROTEIN BINDING; ENZYME STRUCTURE; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; SWINE; THROMBOCYTE;

AMIDINES; AMINO ACID SEQUENCE; ANIMALS; BENZAMIDINES; BINDING SITES; BOTHROPS; CROTALID VENOMS; DIPEPTIDES; ELECTROSTATICS; GLYCOPROTEINS; KALLIKREINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PIPERIDINES; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; STRUCTURAL HOMOLOGY, PROTEIN; THROMBIN; WATER;

BOTHROPS; BOTHROPS JARARACA; CROTALINAE; SERPENTES; SUIDAE; SUS SCROFA; TOBACCO STREAK VIRUS;

EID: 4344573186     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.04746804     Document Type: Article

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