Glucocorticoid receptor heterozygosity combined with lack of receptor auto-induction causes glucocorticoid resistance in jurkat acute lymphoblastic leukemia cells

Cell Death and Differentiation

Volumn 11, Issue , 2004, Pages S65-S72

  Riml, S ^a   Schmidt, S ^b   Ausserlechner, M J ^a   Geley, S ^a   Kofler, R ^a,b  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b TYROLEAN CANCER RESEARCH INSTITUTE   (Austria)

Author keywords

Apoptosis; Glucocorticoid receptor; Glucocorticoid resistance; Lymphoblastic leukemia

Indexed keywords

GLUCOCORTICOID RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALLELE; ANIMAL CELL; ARTICLE; AUTOREGULATION; CELL DEATH; CELL LINE; CONTROLLED STUDY; GENE INACTIVATION; GENE MUTATION; GENE TRANSFER; HETEROZYGOSITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LEUKEMIA CELL LINE; LIGAND BINDING; MICROSCOPY; NONHUMAN; NUCLEAR IMPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; TRANSACTIVATION; TRANSGENICS; VIRUS GENE; WILD TYPE;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; DEXAMETHASONE; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, DOMINANT; GLUCOCORTICOIDS; GREEN FLUORESCENT PROTEINS; HETEROZYGOTE; HUMANS; JURKAT CELLS; KINETICS; LUCIFERASES, RENILLA; LUMINESCENT PROTEINS; MAMMARY TUMOR VIRUS, MOUSE; MICROSCOPY, CONFOCAL; POINT MUTATION; PROTEIN TRANSPORT; RADIOLIGAND ASSAY; RECEPTORS, GLUCOCORTICOID; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION; TRIAMCINOLONE;

EID: 4344561524     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401413     Document Type: Article

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