Humidity-induced changes of the aerodynamic properties of dry powder aerosol formulations containing different carriers

International Journal of Pharmaceutics

Volumn 333, Issue 1-2, 2007, Pages 45-55

  Zeng, Xian Ming ^a   MacRitchie, Helen B ^a   Marriott, Christopher ^a   Martin, Gary P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Dry powder inhaler; Excipients; Fine particle fraction; Formulation; Laser diffraction; Water sorption

Indexed keywords

ALPHA LACTOSE; CARBOHYDRATE DERIVATIVE; DRUG CARRIER; GLUCOSE; MALTOSE; SALBUTAMOL; SORBITOL;

AEROSOL; ARTICLE; DRUG FORMULATION; DRUG STORAGE; DRY POWDER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMIDITY; LASER DIFFRACTION; PARTICLE SIZE; PRIORITY JOURNAL;

ADMINISTRATION, INHALATION; AEROSOLS; ALBUTEROL; BRONCHODILATOR AGENTS; CHEMISTRY, PHARMACEUTICAL; DESICCATION; DRUG CARRIERS; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; GLUCOSE; HUMIDITY; LACTOSE; LASERS; MALTOSE; MICROSCOPY, ELECTRON, SCANNING; NEBULIZERS AND VAPORIZERS; PARTICLE SIZE; POROSITY; POWDER DIFFRACTION; POWDERS; SORBITOL; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS; WATER;

EID: 33847228348     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.09.048     Document Type: Article

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