Nuclease activity of copper(II) complex containing 1,10-phenanthroline-5,6- dione and L-phenylalanine ligands

Frontiers of Chemistry in China

Volumn 3, Issue 2, 2008, Pages 138-142

  Xu, Guangjun ^a,b   Gu, Wen ^a   Ma, Xiaofang ^a   Feng, Li ^a,c   Yan, Shiping ^a   Liao, Daizheng ^a   Cheng, Peng ^a  

^a NANKAI UNIVERSITY   (China)

^b Forth Military Medical University   (China)

^c TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Copper complex; DNA binding; DNA cleavage

Indexed keywords

EID: 43249083378     PISSN: 16733495     EISSN: 16733614     Source Type: Journal    
DOI: 10.1007/s11458-008-0026-z     Document Type: Article

References (18)

1. Erkkilia K E, Odom D T, Barton K J. Recognition and reaction of etallointercalators with DNA. Chem Rev, 1999, 99: 2777-2795
2. Sigman D S, Mazumder A, Perrin D M. Chemical nucleases. Chem Rev, 1993, 93: 2295-2316
3. Huang S G, Martin K. Fluorescent nucleotide derivatives as specific probes for the uncoupling protein: thermodynamics and kinetics of binding and the control by pH. Biochem, 1995, 305: 349-360
4. Ren R, Yang P, Zheng W. A simple copper(II)-L-histidine system for efficient hydrolytic cleavage of DNA. Inorg Chem, 2000, 39: 5454-5463
5. Reichmann M E, Rice S A, Thomas C A. A further examination of the molecular weight and size of desoxypentose nucleic acid. J Am Chem Soc 1954, 76: 3047-3055
6. Xu G J, Kou Y Y, Feng L, Yan S P, Liao DZ, Cheng P. Cu(II) and Ni(II)-1,10-phenanthroline-5,6-dione-amino acid ternary complexes exhibiting pH-sensitive redox properties. Appl Organometal Chem, 2006, 20: 351-356
7. Wolfe A, Shimer G H, Meehan T. Polycyclic aromatic hydrocarbons physically intercalate into duplex regions of denatured DNA. Biochemistry, 1987, 26: 6392-6396
8. Barton J K, Danishefsky A T, Goldberg J M. Tris(phenanthroline) ruthenium(II): stereoselectivity in binding to DNA. J Am Chem Soc, 1984, 106: 2172-2176
9. 2+ with calf thymus DNA. J Phys Chem, 1993, 97: 1707-1714
10. Liu C, Zhou J, Li Q. DNA damage by copper(II) complexes: coordination-structural dependence of reactivities. J Inorg Biochem, 1999, 75: 233-239
11. Zou X H, Ye B H, Li H. Aluminum speciation studies in biological fluids: Part 7. a quantitative investigation of aluminum(III)-malate complex equilibria and their potential implications for aluminum metabolism and toxicity. J Biol Inorg Chem, 2001, 6: 143-150
12. Sedov A, Dunaj-Jurco M, Kabesova M. The possibility of electronic spectra utilization for molecular structure determination in the case of Cu(II) complexes with 2,2′-bipyridyl and o-phenanthroline. Inorg Chim Acta, 1987, 64: L257-263
13. Wolf A, Shimer Jr GH, Meehan T. Polycyclic aromatic hydrocarbons physically intercalate into duplex regions of denatured DNA, Biochemistry, 1987, 26: 6392-6397
14. Baguley B C, Lebret M. Quenching of DNA-ethidium fluorescence by amsacrine and other antitumor agents: a possible electron-transfer effect. Biochemistry, 1984, 23: 937-943
15. Jenkins T C, K.R. Fox (Ed.). Methods in Molecular Biology, vol. 90, drug-DNA interaction protocols, humana press inc, Totowa, New Jersey, 1997, 205-207
16. Pogozelski W K, Tullius T D. Oxidative strand scission of nucleic acids: routes initiated by hydrogen abstraction from the sugar moiety. Chem Rev, 1998, 98: 1089-1107
17. Humphreys K J, Karlin K D, Rokita S E. Targeted strand scission of DNA substrates by a tricopper(II) coordination complex. J Am Chem Soc, 2002, 124: 8055-8066
18. Klinman J. Mechanisms whereby mononuclear copper proteins functionalize organic substrates. Chem Rev, 1996, 96: 2541-2561