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Volumn 20, Issue 3, 2008, Pages 269-274

Varicocele repair: Does it still have a role in infertility treatment?

Author keywords

Infertility; Pathophysiology; Repair; Varicocelectomy

Indexed keywords

ANTIOXIDANT; AQUAPORIN RECEPTOR; DNA; RECEPTOR;

EID: 43149114889     PISSN: 1040872X     EISSN: None     Source Type: Journal    
DOI: 10.1097/GCO.0b013e3282fcc00c     Document Type: Review
Times cited : (71)

References (50)
  • 1
    • 55049095169 scopus 로고    scopus 로고
    • Surgery or embolisation for varicocele in subfertile men
    • CD000479
    • Evers JL, Collins JA. Surgery or embolisation for varicocele in subfertile men. Cochrane Database Syst Rev 2004:CD000479.
    • (2004) Cochrane Database Syst Rev
    • Evers, J.L.1    Collins, J.A.2
  • 2
    • 32044457161 scopus 로고    scopus 로고
    • Treatment of varicocele in subfertile men: The Cochrane Review - a contrary opinion
    • Ficarra V, Cerruto MA, Liguori G, et al. Treatment of varicocele in subfertile men: the Cochrane Review - a contrary opinion. Eur Urol 2006; 49:258-263.
    • (2006) Eur Urol , vol.49 , pp. 258-263
    • Ficarra, V.1    Cerruto, M.A.2    Liguori, G.3
  • 3
    • 34648814355 scopus 로고    scopus 로고
    • Efficacy of varicocelectomy in improving semen parameters: New meta-analytical approach
    • This study is one of two recent, well done meta-analyses that convincingly demonstrates improvement in semen parameters after varicocele repair. The analysis excluded any studies with patients with subclinical varicoceles or normal semen parameters
    • Agarwal A, Deepinder F, Cocuzza M, et al. Efficacy of varicocelectomy in improving semen parameters: new meta-analytical approach. Urology 2007; 70:532-538. This study is one of two recent, well done meta-analyses that convincingly demonstrates improvement in semen parameters after varicocele repair. The analysis excluded any studies with patients with subclinical varicoceles or normal semen parameters.
    • (2007) Urology , vol.70 , pp. 532-538
    • Agarwal, A.1    Deepinder, F.2    Cocuzza, M.3
  • 4
    • 34548452002 scopus 로고    scopus 로고
    • Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis
    • This is the other recent well done meta-analysis to demonstrate the effectiveness of varicocele repair on fertility. Again, this review consisted of only appropriately selected patients and is the only one to include pregnancy data
    • Marmar JL, Agarwal A, Prabakaran S, et al. Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis. Fertil Steril 2007; 88:639-648. This is the other recent well done meta-analysis to demonstrate the effectiveness of varicocele repair on fertility. Again, this review consisted of only appropriately selected patients and is the only one to include pregnancy data.
    • (2007) Fertil Steril , vol.88 , pp. 639-648
    • Marmar, J.L.1    Agarwal, A.2    Prabakaran, S.3
  • 5
    • 0027753948 scopus 로고
    • Decreased blood flow and defective energy metabolism in the varicocele-bearing testicles of rats
    • Hsu HS, Chang LS, Chen MT, Wei YH. Decreased blood flow and defective energy metabolism in the varicocele-bearing testicles of rats. Eur Urol 1994; 25:71-75.
    • (1994) Eur Urol , vol.25 , pp. 71-75
    • Hsu, H.S.1    Chang, L.S.2    Chen, M.T.3    Wei, Y.H.4
  • 6
    • 0029080125 scopus 로고
    • Alteration of testicular microvascular pressures during venous pressure elevation
    • Sweeney TE, Rozum JS, Gore RW. Alteration of testicular microvascular pressures during venous pressure elevation. Am J Physiol 1995; 269 (1 Pt 2):H37-H45.
    • (1995) Am J Physiol , vol.269 , Issue.1 PART 2
    • Sweeney, T.E.1    Rozum, J.S.2    Gore, R.W.3
  • 7
    • 0028564955 scopus 로고
    • The effect of varicoceles on testicular blood flow in man
    • Ross JA, Watson NE Jr, Jarow JP. The effect of varicoceles on testicular blood flow in man. Urology 1994; 44:535-539.
    • (1994) Urology , vol.44 , pp. 535-539
    • Ross, J.A.1    Watson Jr, N.E.2    Jarow, J.P.3
  • 8
    • 0031318197 scopus 로고    scopus 로고
    • Volocimetric evaluation of spermatic vessels with echo color Doppler in patients with idiopathic varicocele
    • Grasso Leanza F, Pepe P, Panella P, Pepe F. Volocimetric evaluation of spermatic vessels with echo color Doppler in patients with idiopathic varicocele. Minerva Urol Nefrol 1997; 49:179-182.
    • (1997) Minerva Urol Nefrol , vol.49 , pp. 179-182
    • Grasso Leanza, F.1    Pepe, P.2    Panella, P.3    Pepe, F.4
  • 9
    • 34248578239 scopus 로고    scopus 로고
    • Unsal A, Turgut AT, Taskin F, et al. Resistance and pulsatility index increase in capsular branches of testicular artery: indicator of impaired testicular microcirculation in varicocele? J Clin Ultrasound 2007; 35:191-195. The study re-visits the issue of impaired microcirculation in the setting of varicocele using newer technology.
    • Unsal A, Turgut AT, Taskin F, et al. Resistance and pulsatility index increase in capsular branches of testicular artery: indicator of impaired testicular microcirculation in varicocele? J Clin Ultrasound 2007; 35:191-195. The study re-visits the issue of impaired microcirculation in the setting of varicocele using newer technology.
  • 10
    • 0027407190 scopus 로고
    • Stimulated reactive oxygen species generation in the spermatozoa of infertile men
    • Weese DL, Peaster ML, Himsl KK, et al. Stimulated reactive oxygen species generation in the spermatozoa of infertile men. J Urol 1993; 149:64-67.
    • (1993) J Urol , vol.149 , pp. 64-67
    • Weese, D.L.1    Peaster, M.L.2    Himsl, K.K.3
  • 11
    • 0032759048 scopus 로고    scopus 로고
    • The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility
    • Sharma RK, Pasqualotto FF, Nelson DR, et al. The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility. Hum Reprod 1999; 14:2801-2807.
    • (1999) Hum Reprod , vol.14 , pp. 2801-2807
    • Sharma, R.K.1    Pasqualotto, F.F.2    Nelson, D.R.3
  • 12
    • 7944229250 scopus 로고    scopus 로고
    • Relationship of interleukin-6 with semen characteristics and oxidative stress in patients with varicocele
    • Nallella KP, Allamaneni SS, Pasqualotto FF, et al. Relationship of interleukin-6 with semen characteristics and oxidative stress in patients with varicocele. Urology 2004; 64:1010-1013.
    • (2004) Urology , vol.64 , pp. 1010-1013
    • Nallella, K.P.1    Allamaneni, S.S.2    Pasqualotto, F.F.3
  • 13
    • 0033813095 scopus 로고    scopus 로고
    • The role of reactive oxygen species in testicular dysfunction associated with varicocele
    • Koksal IT, Tefekli A, Usta M, et al. The role of reactive oxygen species in testicular dysfunction associated with varicocele. BJU Int 2000; 86:549-552.
    • (2000) BJU Int , vol.86 , pp. 549-552
    • Koksal, I.T.1    Tefekli, A.2    Usta, M.3
  • 14
    • 34547675729 scopus 로고    scopus 로고
    • Shiraishi K, Naito K. Effects of 4-hydroxy-2-nonenal, a marker of oxidative stress, on spermatogenesis and expression of p53 protein in male infertility. J Urol 2007; 178 (3 Pt 1):1012-1017; discussion 7.
    • Shiraishi K, Naito K. Effects of 4-hydroxy-2-nonenal, a marker of oxidative stress, on spermatogenesis and expression of p53 protein in male infertility. J Urol 2007; 178 (3 Pt 1):1012-1017; discussion 7.
  • 15
    • 33947537428 scopus 로고    scopus 로고
    • Mast cells, their adenosine receptors and reactive oxygen species in chronic inflammatory pathologies of childhood
    • Renke J, Popadiuk S, Wozniak M, et al. Mast cells, their adenosine receptors and reactive oxygen species in chronic inflammatory pathologies of childhood. Przegl Lek 2006; 63:554-556.
    • (2006) Przegl Lek , vol.63 , pp. 554-556
    • Renke, J.1    Popadiuk, S.2    Wozniak, M.3
  • 16
    • 38449115468 scopus 로고    scopus 로고
    • Seminal mast cells in infertile asthenozoospermic males
    • This study cites a new source for ROS in the setting of varicocele, adding to the mounting body of evidence for ROS as a major factor in varicocele-induced infertility
    • El-Karaksy A, Mostafa T, Shaeer OK, et al. Seminal mast cells in infertile asthenozoospermic males. Andrologia 2007; 39:244-247. This study cites a new source for ROS in the setting of varicocele, adding to the mounting body of evidence for ROS as a major factor in varicocele-induced infertility.
    • (2007) Andrologia , vol.39 , pp. 244-247
    • El-Karaksy, A.1    Mostafa, T.2    Shaeer, O.K.3
  • 17
    • 33745493670 scopus 로고    scopus 로고
    • Generation of 4-hydroxy-2-nonenal modified proteins in testes predicts improvement in spermatogenesis after varicocelectomy
    • Shiraishi K, Naito K. Generation of 4-hydroxy-2-nonenal modified proteins in testes predicts improvement in spermatogenesis after varicocelectomy. Fertil Steril 2006; 86:233-235.
    • (2006) Fertil Steril , vol.86 , pp. 233-235
    • Shiraishi, K.1    Naito, K.2
  • 18
    • 36249008053 scopus 로고    scopus 로고
    • Oxidative stress biomarkers and hormonal profile in human patients undergoing varicocelectomy
    • A well done and contemporary study that shows the beneficial effects of varicocele repair on multiple markers of oxidative stress. The levels of these markers decreased to the levels seen in controls without varicocele and total antioxidant capacity increased to levels seen in controls
    • Hurtado de Catalfo GE, Ranieri-Casilla A, Marra FA, et al. Oxidative stress biomarkers and hormonal profile in human patients undergoing varicocelectomy. Int J Androl 2007; 30:519-530. A well done and contemporary study that shows the beneficial effects of varicocele repair on multiple markers of oxidative stress. The levels of these markers decreased to the levels seen in controls without varicocele and total antioxidant capacity increased to levels seen in controls.
    • (2007) Int J Androl , vol.30 , pp. 519-530
    • Hurtado de Catalfo, G.E.1    Ranieri-Casilla, A.2    Marra, F.A.3
  • 19
    • 38849115914 scopus 로고    scopus 로고
    • Attenuation of oxidative stress after varicocelectomy in subfertile patients with varicocele
    • Another study showing reduced oxidative stress after varicocele repair, an example of how varicocele repair might improve fertility
    • Chen SS, Huang WJ, Chang LS, Wei YH. Attenuation of oxidative stress after varicocelectomy in subfertile patients with varicocele. J Urol 2008; 179:639-642. Another study showing reduced oxidative stress after varicocele repair, an example of how varicocele repair might improve fertility.
    • (2008) J Urol , vol.179 , pp. 639-642
    • Chen, S.S.1    Huang, W.J.2    Chang, L.S.3    Wei, Y.H.4
  • 20
    • 0348110637 scopus 로고    scopus 로고
    • Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele
    • Saleh RA, Agarwal A, Sharma RK, et al. Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele. Fertil Steril 2003; 80:1431-1436.
    • (2003) Fertil Steril , vol.80 , pp. 1431-1436
    • Saleh, R.A.1    Agarwal, A.2    Sharma, R.K.3
  • 21
    • 1942469904 scopus 로고    scopus 로고
    • Apoptosis and kinematics of ejaculated spermatozoa in patients with varicocele
    • Chen CH, Lee SS, Chen DC, et al. Apoptosis and kinematics of ejaculated spermatozoa in patients with varicocele. J Androl 2004; 25:348-353.
    • (2004) J Androl , vol.25 , pp. 348-353
    • Chen, C.H.1    Lee, S.S.2    Chen, D.C.3
  • 22
    • 30844437922 scopus 로고    scopus 로고
    • Infertile men with varicocele show a high relative proportion of sperm cells with intense nuclear damage level, evidenced by the sperm chromatin dispersion test
    • Enciso M, Muriel L, Fernandez JL, et al. Infertile men with varicocele show a high relative proportion of sperm cells with intense nuclear damage level, evidenced by the sperm chromatin dispersion test. J Androl 2006; 27:106-111.
    • (2006) J Androl , vol.27 , pp. 106-111
    • Enciso, M.1    Muriel, L.2    Fernandez, J.L.3
  • 23
    • 33645292883 scopus 로고    scopus 로고
    • Increased sperm DNA damage in patients with varicocele: Relationship with seminal oxidative stress
    • Smith R, Kaune H, Parodi D, et al. Increased sperm DNA damage in patients with varicocele: relationship with seminal oxidative stress. Hum Reprod 2006; 21:986-993.
    • (2006) Hum Reprod , vol.21 , pp. 986-993
    • Smith, R.1    Kaune, H.2    Parodi, D.3
  • 24
    • 0032196723 scopus 로고    scopus 로고
    • Role of apoptosis in testicular tissue damage caused by varicocele
    • Simsek F, Turkeri L, Cevik I, et al. Role of apoptosis in testicular tissue damage caused by varicocele. Arch Esp Urol 1998; 51:947-950.
    • (1998) Arch Esp Urol , vol.51 , pp. 947-950
    • Simsek, F.1    Turkeri, L.2    Cevik, I.3
  • 25
    • 0034839692 scopus 로고    scopus 로고
    • The pathophysiology of varicoceles in the light of current molecular and genetic information
    • Marmar JL. The pathophysiology of varicoceles in the light of current molecular and genetic information. Hum Reprod Update 2001; 7:461-472.
    • (2001) Hum Reprod Update , vol.7 , pp. 461-472
    • Marmar, J.L.1
  • 26
    • 36849005766 scopus 로고    scopus 로고
    • Role of aquaporins in endothelial water transport
    • Verkman A. Role of aquaporins in endothelial water transport. J Anat 2002; 200:528.
    • (2002) J Anat , vol.200 , pp. 528
    • Verkman, A.1
  • 27
    • 12844287452 scopus 로고    scopus 로고
    • Immunoexpression of aquaporin-1 in adolescent varicocele testes: Possible significance for fluid reabsorption
    • Nicotina PA, Romeo C, Arena S, et al. Immunoexpression of aquaporin-1 in adolescent varicocele testes: possible significance for fluid reabsorption. Urology 2005; 65:149-152.
    • (2005) Urology , vol.65 , pp. 149-152
    • Nicotina, P.A.1    Romeo, C.2    Arena, S.3
  • 28
    • 34548083777 scopus 로고    scopus 로고
    • Effects of varicocele on electrical field stimulation-induced biphasic twitch responses in the ipsilateral and contralateral rat vasa deferentia
    • Ozen IO, Moralioglu S, Vural IM, et al. Effects of varicocele on electrical field stimulation-induced biphasic twitch responses in the ipsilateral and contralateral rat vasa deferentia. Eur Surg Res 2007; 39:269-274.
    • (2007) Eur Surg Res , vol.39 , pp. 269-274
    • Ozen, I.O.1    Moralioglu, S.2    Vural, I.M.3
  • 29
    • 33846001719 scopus 로고    scopus 로고
    • Expression of leptin and leptin receptor in the testis of fertile and infertile patients
    • Ishikawa T, Fujioka H, Ishimura T, et al. Expression of leptin and leptin receptor in the testis of fertile and infertile patients. Andrologia 2007; 39:22-27.
    • (2007) Andrologia , vol.39 , pp. 22-27
    • Ishikawa, T.1    Fujioka, H.2    Ishimura, T.3
  • 30
    • 33947215453 scopus 로고    scopus 로고
    • Immunolocalization of glial cell-derived neurotrophic factor (GDNF) and its receptor GFR-alpha1 in varicocele-induced rat testis
    • Akkoyunlu G, Erdogru T, Seval Y, et al. Immunolocalization of glial cell-derived neurotrophic factor (GDNF) and its receptor GFR-alpha1 in varicocele-induced rat testis. Acta Histochem 2007; 109:130-137.
    • (2007) Acta Histochem , vol.109 , pp. 130-137
    • Akkoyunlu, G.1    Erdogru, T.2    Seval, Y.3
  • 31
    • 24044527490 scopus 로고    scopus 로고
    • Increased expression of Leydig cell haem oxygenase-1 preserves spermatogenesis in varicocele
    • Shiraishi K, Naito K. Increased expression of Leydig cell haem oxygenase-1 preserves spermatogenesis in varicocele. Hum Reprod 2005; 20:2608-2613.
    • (2005) Hum Reprod , vol.20 , pp. 2608-2613
    • Shiraishi, K.1    Naito, K.2
  • 32
    • 0036016582 scopus 로고    scopus 로고
    • Does treatment of varicocele improve male fertility? Results of the 'Deutsche Varikozelenstudie', a multicentre study of 14 collaborating centres
    • Krause W, Muller HH, Schafer H, Weidner W. Does treatment of varicocele improve male fertility? Results of the 'Deutsche Varikozelenstudie', a multicentre study of 14 collaborating centres. Andrologia 2002; 34:164-171.
    • (2002) Andrologia , vol.34 , pp. 164-171
    • Krause, W.1    Muller, H.H.2    Schafer, H.3    Weidner, W.4
  • 33
    • 84907126117 scopus 로고
    • Treatment of varicocele and male fertility
    • Breznik R, Vlaisavljevic V, Borko E. Treatment of varicocele and male fertility. Arch Androl 1993; 30:157-160.
    • (1993) Arch Androl , vol.30 , pp. 157-160
    • Breznik, R.1    Vlaisavljevic, V.2    Borko, E.3
  • 34
    • 0026556372 scopus 로고
    • Long-term results of varicocelectomy
    • Rageth JC, Unger C, DaRugna D, et al. Long-term results of varicocelectomy. Urol Int 1992; 48:327-331.
    • (1992) Urol Int , vol.48 , pp. 327-331
    • Rageth, J.C.1    Unger, C.2    DaRugna, D.3
  • 35
    • 0036718191 scopus 로고    scopus 로고
    • The effects of subinguinal varicocelectomy on Kruger morphology and semen parameters
    • Kibar Y, Seckin B, Erduran D. The effects of subinguinal varicocelectomy on Kruger morphology and semen parameters. J Urol 2002; 168:1071-1074.
    • (2002) J Urol , vol.168 , pp. 1071-1074
    • Kibar, Y.1    Seckin, B.2    Erduran, D.3
  • 36
    • 0028861217 scopus 로고
    • Controlled trial of high spermatic vein ligation for varicocele in infertile men
    • Madgar I, Weissenberg R, Lunenfeld B, et al. Controlled trial of high spermatic vein ligation for varicocele in infertile men. Fertil Steril 1995; 63:120-124.
    • (1995) Fertil Steril , vol.63 , pp. 120-124
    • Madgar, I.1    Weissenberg, R.2    Lunenfeld, B.3
  • 37
    • 0028059182 scopus 로고
    • Subinguinal microsurgical varicocelectomy: A technical critique and statistical analysis of semen and pregnancy data
    • Marmar JL, Kim Y. Subinguinal microsurgical varicocelectomy: a technical critique and statistical analysis of semen and pregnancy data. J Urol 1994; 152:1127-1132.
    • (1994) J Urol , vol.152 , pp. 1127-1132
    • Marmar, J.L.1    Kim, Y.2
  • 38
    • 33749998390 scopus 로고    scopus 로고
    • Report on varicocele and infertility
    • Guidelines clearly outline proper selection criteria for varicocele repair. Practice Committee of the American Society for Reproductive Medicine
    • Practice Committee of the American Society for Reproductive Medicine. Report on varicocele and infertility. Fertil Steril. 2006;86:S93-S95. Guidelines clearly outline proper selection criteria for varicocele repair.
    • (2006) Fertil Steril , vol.86
  • 39
    • 0028895409 scopus 로고
    • Methodologic guidelines for systematic reviews of randomized control trials in healthcare from the Potsdam Consultation on Meta-Analysis
    • Cook DJ, Sackett DL, Spitzer WO. Methodologic guidelines for systematic reviews of randomized control trials in healthcare from the Potsdam Consultation on Meta-Analysis. J Clin Epidemiol 1995; 48:167-171.
    • (1995) J Clin Epidemiol , vol.48 , pp. 167-171
    • Cook, D.J.1    Sackett, D.L.2    Spitzer, W.O.3
  • 40
    • 0025800086 scopus 로고
    • Subclinical varicocele: The effectiveness of varicocelectomy
    • McClure RD, Khoo D, Jarvi K, Hricak H. Subclinical varicocele: the effectiveness of varicocelectomy. J Urol 1991; 145:789-791.
    • (1991) J Urol , vol.145 , pp. 789-791
    • McClure, R.D.1    Khoo, D.2    Jarvi, K.3    Hricak, H.4
  • 41
    • 0026533749 scopus 로고
    • Clinical versus subclinical varicocele: Improvement in fertility after varicocelectomy
    • Dhabuwala CB, Hamid S, Moghissi KS. Clinical versus subclinical varicocele: improvement in fertility after varicocelectomy. Fertil Steril 1992; 57:854-857.
    • (1992) Fertil Steril , vol.57 , pp. 854-857
    • Dhabuwala, C.B.1    Hamid, S.2    Moghissi, K.S.3
  • 42
    • 33745497553 scopus 로고    scopus 로고
    • Correlation of ultrasound-measured venous size and reversal of flow with Valsalva with improvement in semen-analysis parameters after varicocelectomy
    • Schiff JD, Li PS, Goldstein M. Correlation of ultrasound-measured venous size and reversal of flow with Valsalva with improvement in semen-analysis parameters after varicocelectomy. Fertil Steril 2006; 86:250-252.
    • (2006) Fertil Steril , vol.86 , pp. 250-252
    • Schiff, J.D.1    Li, P.S.2    Goldstein, M.3
  • 43
    • 33751054074 scopus 로고    scopus 로고
    • Libman J, Jarvi K, Lo K, Zini A. Beneficial effect of microsurgical varicocelectomy is superior for men with bilateral versus unilateral repair. J Urol 2006; 176 (6 Pt 1):2602-2605; discussion 5.
    • Libman J, Jarvi K, Lo K, Zini A. Beneficial effect of microsurgical varicocelectomy is superior for men with bilateral versus unilateral repair. J Urol 2006; 176 (6 Pt 1):2602-2605; discussion 5.
  • 44
    • 18744366390 scopus 로고    scopus 로고
    • Induction of spermatogenesis in azoospermic men after internal spermatic vein embolization for the treatment of varicocele
    • Gat Y, Bachar GN, Everaert K, et al. Induction of spermatogenesis in azoospermic men after internal spermatic vein embolization for the treatment of varicocele. Hum Reprod 2005; 20:1013-1017.
    • (2005) Hum Reprod , vol.20 , pp. 1013-1017
    • Gat, Y.1    Bachar, G.N.2    Everaert, K.3
  • 45
    • 2942518006 scopus 로고    scopus 로고
    • Role of varicocelectomy in men with nonobstructive azoospermia
    • Schlegel PN, Kaufmann J. Role of varicocelectomy in men with nonobstructive azoospermia. Fertil Steril 2004; 81:1585-1588.
    • (2004) Fertil Steril , vol.81 , pp. 1585-1588
    • Schlegel, P.N.1    Kaufmann, J.2
  • 46
    • 3042822468 scopus 로고    scopus 로고
    • Induction of spermatogenesis by inguinal varicocele repair in azoospermic men
    • Cakan M, Altug U. Induction of spermatogenesis by inguinal varicocele repair in azoospermic men. Arch Androl 2004; 50:145-150.
    • (2004) Arch Androl , vol.50 , pp. 145-150
    • Cakan, M.1    Altug, U.2
  • 47
    • 32944478584 scopus 로고    scopus 로고
    • Induction of spermatogenesis in azoospermic men after varicocelectomy repair: An update
    • Pasqualotto FF, Sobreiro BP, Hallak J, et al. Induction of spermatogenesis in azoospermic men after varicocelectomy repair: an update. Fertil Steril 2006; 85:635-639.
    • (2006) Fertil Steril , vol.85 , pp. 635-639
    • Pasqualotto, F.F.1    Sobreiro, B.P.2    Hallak, J.3
  • 48
    • 0031038162 scopus 로고    scopus 로고
    • Is assisted reproduction the optimal treatment for varicoceleassociated male infertility? A cost-effectiveness analysis
    • Schlegel PN. Is assisted reproduction the optimal treatment for varicoceleassociated male infertility? A cost-effectiveness analysis. Urology 1997; 49:83-90.
    • (1997) Urology , vol.49 , pp. 83-90
    • Schlegel, P.N.1
  • 49
    • 0036893904 scopus 로고    scopus 로고
    • The cost-effectiveness of treatment for varicocele related infertility
    • Penson DF, Paltiel AD, Krumholz HM, Palter S. The cost-effectiveness of treatment for varicocele related infertility. J Urol 2002; 168:2490-2494.
    • (2002) J Urol , vol.168 , pp. 2490-2494
    • Penson, D.F.1    Paltiel, A.D.2    Krumholz, H.M.3    Palter, S.4
  • 50
    • 27544502511 scopus 로고    scopus 로고
    • Surgery or assisted reproduction? A decision analysis of treatment costs in male infertility
    • discussion 31
    • Meng MV, Greene KL, Turek PJ. Surgery or assisted reproduction? A decision analysis of treatment costs in male infertility. J Urol 2005; 174:1926-1931; discussion 31.
    • (2005) J Urol , vol.174 , pp. 1926-1931
    • Meng, M.V.1    Greene, K.L.2    Turek, P.J.3


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