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Marmar JL, Agarwal A, Prabakaran S, et al. Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis. Fertil Steril 2007; 88:639-648. This is the other recent well done meta-analysis to demonstrate the effectiveness of varicocele repair on fertility. Again, this review consisted of only appropriately selected patients and is the only one to include pregnancy data.
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Unsal A, Turgut AT, Taskin F, et al. Resistance and pulsatility index increase in capsular branches of testicular artery: indicator of impaired testicular microcirculation in varicocele? J Clin Ultrasound 2007; 35:191-195. The study re-visits the issue of impaired microcirculation in the setting of varicocele using newer technology.
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A well done and contemporary study that shows the beneficial effects of varicocele repair on multiple markers of oxidative stress. The levels of these markers decreased to the levels seen in controls without varicocele and total antioxidant capacity increased to levels seen in controls
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Hurtado de Catalfo GE, Ranieri-Casilla A, Marra FA, et al. Oxidative stress biomarkers and hormonal profile in human patients undergoing varicocelectomy. Int J Androl 2007; 30:519-530. A well done and contemporary study that shows the beneficial effects of varicocele repair on multiple markers of oxidative stress. The levels of these markers decreased to the levels seen in controls without varicocele and total antioxidant capacity increased to levels seen in controls.
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Another study showing reduced oxidative stress after varicocele repair, an example of how varicocele repair might improve fertility
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Chen SS, Huang WJ, Chang LS, Wei YH. Attenuation of oxidative stress after varicocelectomy in subfertile patients with varicocele. J Urol 2008; 179:639-642. Another study showing reduced oxidative stress after varicocele repair, an example of how varicocele repair might improve fertility.
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