Oxidative stress biomarkers and hormonal profile in human patients undergoing varicocelectomy

International Journal of Andrology

Volumn 30, Issue 6, 2007, Pages 519-530

  Hurtado De Catalfo, Graciela E ^a   Ranieri Casilla, Adalberto ^b   Marra, Fernando A ^c   De Alaniz, María J T ^a   Marra, Carlos A ^a  

^a INSTITUTO DE INVESTIGACIONES BIOQUÍMICAS DE LA PLATA INIBIOLP   (Argentina)

^b Hospital Interzonal General de Agudos de La Plata   (Argentina)

^c Servicio de Medicina General   (Argentina)

Author keywords

Antioxidant enzymes; Hormonal levels; Human varicocelectomy; Oligoelements; Oxidative stress; Semen characteristics

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; CARBONYL DERIVATIVE; DNA FRAGMENT; FOLLITROPIN; LUTEINIZING HORMONE; PROTEIN; SELENIUM; TESTOSTERONE; ZINC;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA DETERMINATION; ENZYME ACTIVITY; FOLLITROPIN BLOOD LEVEL; HUMAN; HUMAN CELL; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MALE FERTILITY; MALE GENITAL SYSTEM SURGERY; MALE INFERTILITY; MEDICAL EXAMINATION; OXIDATIVE STRESS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SEMINAL PLASMA; SPERMATIC VEIN; SPERMATOZOON; SURGICAL PATIENT; TESTOSTERONE BLOOD LEVEL; VARICOCELE; VARICOCELECTOMY; ZINC BLOOD LEVEL;

ADULT; ANTIOXIDANTS; ARGENTINA; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DNA FRAGMENTATION; FOLLICLE STIMULATING HORMONE; HORMONES; HUMANS; INFERTILITY, MALE; LUTEINIZING HORMONE; MALE; OXIDATIVE STRESS; PROTEIN CARBONYLATION; SEMEN; SEMINAL PLASMA PROTEINS; SPERMATOZOA; TESTOSTERONE; TIME FACTORS; TREATMENT OUTCOME; VARICOCELE; VASCULAR SURGICAL PROCEDURES;

EID: 36249008053     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2007.00753.x     Document Type: Article

References (71)

1. Aebi, H. (1984) Catalase in vitro. Methods in Enzymology 105, 121 126.
2. Aitken, R. J. Fisher, H. (1994) Reactive oxygen species generation and human spermatozoa: the balance of benefits and risk. Bioassays 16, 259 267.
3. Aitken, R. J., Clarkson, J. S. Hargreave, T. B. (1989) Analysis of the relationship between defective sperm function and generation of reactive oxygen species in cases of oligospermia. Journal of Andrology 10, 214 220.
4. Alkan, I., Simsek, F. Haklaar, G. (1997) Reactive oxygen species production by spermatozoa of patients with idiopathic infertility: relationship to seminal plasma antioxidants. The Journal of Urology 157, 140 143.
5. Allamaneni, S. S., Naughton, C. K., Sharma, R. K., Thomas, A. J. Agarwal, A. (2004) Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size. Fertility and Sterility 82, 1684 1686.
6. Asensi, M., Sastre, J., Pallardo, F. V., Delaasunción, J. G., Estrela, J. M. Vina, J. (1994) A high-performance liquid chromatography meted for measurement of oxidized glutathione in biological samples. Analytical Biochemistry 217, 323 328.
7. Battaglia, C., Guilini, S., Gegnani, G., Di Girolamo, R., Paganelli, S., Facchinetti, F. Volpe, A. (2000) Seminal plasma nitrite/nitrate and intratesticular Doppler flow in fertile and infertile subjects. Human Reproduction 15, 2554 2558.
8. Battaglia, C., Guilini, S., Regnani, G., Madgar, I., Facchinetti, F. Volpe, A. (2001) Intratesticular Doppler flow, seminal plasma nitrites/nitrates, and non-obstructive sperm extraction from patients with obstructive and non-obstructive azoospermia. Fertility and Sterility 75, 1088 1094.
9. Benzie, I. F. F. Strain, J. J. (1996) The ferric reducing ability of plasma as a measure of antioxidant power: the FRAP assay. Analytical Biochemistry 238, 70 76.
10. Benzie, I. F. F., Chung, W. Y. Strain, J. J. (1999) Antioxidant (reducing) efficiency of ascorbate in plasma is not affected by concentration. Journal of Nutritional Biochemistry 10, 146 150.
11. Berlett, B. Satadtman, E. R. (1997) Protein oxidation in aging, disease, and oxidative stress. Journal of Biological Chemistry 272, 20313 20316.
12. Berlin, E., Bhathera, S. J., Judd, J. T., Nair, P. P., Jones, D. Y. Tayler, P. R. (1989) Dietary fat and hormonal effects on erythrocyte membrane fluidity and lipid composition in adult women. Metabolism 8, 790 796.
13. Brigelius, R., Muckel, C., Akerboom, T. P. M. Sies, H. (1983) Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide. Biochemical Pharmacology 32, 2529 2534.
14. Buttriss, J. L. Diplock, A. T. (1984) High-performance liquid chromatography methods for vitamin E in tissues. Methods in Enzymology 105, 131 138.
15. Callberg, E. Mannervick, A. (1985) Glutathione reductase. Methods in Enzymology 113, 484 495.
16. Catigiani, G. L. Bieri, J. G. (1983) Simultaneous determination of retinal and alpha-tocopherol in serum or plasma by liquid chromatography. Clinical Chemistry 29, 708 712.
17. Chen, S. S., Chang, L. S. Whi, Y. H. (2001) Oxidative damage to proteins and decrease of antioxidant capacity in patients with varicocele. Free Radical Biology Medicine 30, 1328 1334.
18. Chen, S. S., Chang, L. S., Chen, H. W. Wei, Y. H. (2002) Polymorphisms of glutathione S-transferase M1 and male infertility in Taiwanese patients with varicocele. Human Reproduction 17, 718 725.
19. Chia, S. E., Ong, C. N., Chua, L. H., Ho, L. M. Tay, S. K. (2000) Comparison of zinc concentration in blood and seminal plasma and the various sperm parameters between fertile and infertile men. Journal of Andrology 21, 53 57.
20. Ciolino, H. P. Levine, R. L. (1997) Modification of proteins in endothelial cell death during oxidative stress. Free Radical Biology Medicine 22, 1277.
21. Coniglio, J. G. (1994) Testicular lipids. Progress in Lipid Research 33, 387 401.
22. Daitch, J. A., Bedaiwy, M. A., Pasqualotto, E. B., Hendin, B. N., Hallak, J., Falcone, T., Thomas, A. J., Jr., Nelson, D. R. Agarwal, A. (2001) Varicocelectomy improves intrauterine insemination success rates in men with varicocele. Journal of Urology 165, 1510 1513.
23. De Lamirande, E. Gagnon, C. (1995) Impact of reactive species on spermatozoa: a balancing act between beneficial and detrimental effects. Human Reproduction 10, 15 21.
24. El-Demerdash, F. M., Yosouf, M. I., Kedwany, F. S. Baghdadi, H. H. (2004) Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and seen quality of male rats:protective effects of vitamin E and β-carotene. Food Chem Toxicol 42, 1563 1571.
25. Flohé, L. Ötting, F. (1984) Superoxide dismutase assays. Methods in Enzymology 105, 93 114.
26. Folch, J., Lees, M. SloaneStanley, G. A. (1957) A simple method for the isolation and purification of total lipids from animal tissues. Journal of Biological Chemistry 226, 497 509.
27. Ghosh, P. K. York, J. P. (1994) Changes in testicular testosterone and acid and alkaline phosphatase activity in testis and accessory sex organs after induction of varicocele in Noble rats. Journal of Surgical Research 56, 271 276.
28. Gil, L., Martínez, G., González, I., Tarinas, A., Alvarez, A., Giuliani, A., Molina, R., Tápanes, R., Pérez, J. León, O. S. (2003) Contribution to characterization of oxidative stress in HIV/AIDS patients. Pharmacological Research 47, 217 224.
29. Gomez, E., Buckingha, D. W. Brindle, J. (1996) Development of an image analysis system to monitor the retention of residual cytoplasm by human spermatozoa: correlation with biochemical markers of the cytoplasmic space, oxidative stress, and sperm function. Journal of Andrology 17, 276 287.
30. Habib, W. H., Pabst, M. J. Jakoby, W. B. (1984) Glutathione-S- transferases, the first enzymatic step in mercapturic acid formation. J Biol Chem 249, 7130 7139.
31. Habib, H. T., Chacko, M., Fawzi, A., Hilal, A. S. Dashti, H. M. (2002) Antioxidant enzyme level in the testes of cirrhotic rats. Nutrition 18, 56 59.
32. Hendin, B. N., Kollettis, P. N. Sharma, R. K. (1999a) Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity. The Journal of Urology 161, 1831 1834.
33. Hendin, B. N., Kolettis, P. N., Sharma, R. K., Thomas, A. J., Jr. Agarwal, A. (1999b) Varicocele is associated with elevated spermatozoal reactive oxygen species production and diminished seminal plasma antioxidant capacity. The Journal of Urology 161, 1831 1834.
34. Hudson, R. W., Perez-Murero, R. A. Crawford, V. A. (1985) Hormonal parameters of men with varicocele before and after varicocelectomy. Fertility and Sterility 43, 905 910.
35. Kamischke, A. Nieschlag, E. (1999) Analysis of medical treatment of male infertility. Human Reproduction 14, 1 23.
36. Kamischke, A. Nieschlag, E. (2001) Varicocele treatment in the light of evidence-based andrology. Human Reproduction Update 7, 65 69.
37. Keating, J., Grundy, C. E. Fivey, P. S. (1997) Investigation into the association between the presence of cytoplasmic residues on the human sperm midpiece and defective sperm function. Journal of Reproduction and Fertility 110, 71 77.
38. Koksal, I. T., Tefleki, A. Usta, M. (2000) The role of reactive oxygen species in testicular dysfunction associated with varicocele. British Journal of Urology 86, 549 552.
39. Lenzi, I. T., Picardo, M. Gandini, L. (1996) Lipids of the sperm plasma membrane: from polyunsaturated fatty acids considered as markers of sperm function to possible scavenger. Human Reproduction Update 2, 246 256.
40. Levine, R. L., Garland, D. Oliver, C. N. (1990) Determination of carbonyl content in oxidatively modified proteins. Methods in Enzymology 186, 464 478.
41. Lopes, L. G., Jurisicova, A. Sun, J. (1998) Reactive oxygen species: potential cause for DNA fragmentation in human spermatozoa. Human Reproduction 13, 896 900.
42. Lowry, O. H., Rosebrough, M. J., Farr, A. J. Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 193, 275 295.
43. Mancini, A., Conte, G. Milardi, D. (1998) Relationship between sperm cell ubiquinone and seminal parameters in subjects with and without varicocele. Andrologia 30, 1 4.
44. Marks, J. J., McMahon, R. Lipshulz, I. I. (1986) Predictive parameters of successful varicocele repair. The Journal of Urology 136, 609 612.
45. Marra, C. A., Mangioni, J. O., Tavella, M., Alaniz, M. J. T., de Ortiz, D. Sala, C. (1998) Hormonal-induced changes on the lipid composition and DPH fluorescence anisotropy of erythrocyte ghosts from pre- and post-menopausal women. Acta Physiologica, Pharmacologica et Therapeutica Latinoamericana 48, 8 17.
46. Meagier, E. Fitzgerald, G. A. (2000) Indices of lipid peroxidation in vivo: strengths and limitations. Free Radical Biology Medicine 28, 1745 1750.
47. Menditto, A., Pietraforte, D. Minetti, M. (1997) Ascorbic acid in human seminal plasma is protected from iron-mediated oxidation, but is potentially exposed to cooper-induced damage. Human Reproduction 12, 1699 1705.
48. Murugesam, P., Kanagaraj, P., Yuvaraj, S., Balasubramanian, K., Aruldhas, M. M. Arunakaran, J. (2005) The inhibitory effects of polychlorinated biphenyl Aroclor 1254 on Leydig cell LH receptors, steroidogenic enzymes and antioxidant enzymes in adult rats. Reproductive Toxicology 20, 117 126.
49. Naughton, C., Nangia, A. K. Agarwal, A. (2001) Varicocele and male infertility: Part II. Pathophysiology of varicocele in male infertility. Human Reproduction Update 7, 473 481.
50. Özbek, E., Turkoz, Y., Gokdeniz, R., Davarci, M. Ozugurlu, F. (2000) Increased nitric oxide production in the spermatic vein of patients with varicocele. European Urology 37, 172 175.
51. Özdamar, A. S., Soylu, A. G., Culha, M. Gökalp, A. (2004) Testicular oxidative stress. Effects of experimental varicocele in adolescent rats. Urologia 73, 343 347.
52. Pasqualotto, F., Sharma, R. K., Nelson, D. R., Thomas, A. J. Agarwal, A. (2000) Relationship between oxidative stress semen characteristics, and clinical diagnosis in men undergoing infertility investigation. Fertility and Sterility 73, 459 464.
53. Pomerantz, D. K. Pitelka, V. (1998) Nitric oxide is a mediator of the inhibitory effect of activated macrophages on production of androgen by the Leydig cell of the mouse. Endocrinology 139, 922 931.
54. Rajimakers, M. T. M., Roelofs, H. M. J., Steegers, E. A. P., Steegers-Theunissen, R. P. M., Mulder, T. P. J., Knapen, M. F. C. M., Wong, W. Y. Peters, W. H. M. (2003) Glutathione and glutathione-S-transferases A1-1 and P1-1 in seminal plasma may play a role in protecting against oxidative damage to spermatozoa. Fertility and Sterility 79, 169 172.
55. Reznick, A. Z. Packer, L. (1994) Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods of Enzymology 233, 357 363.
56. Rosselli, M., Dubey, R. K., Imthurn, B., Macas, E. Keller, P. J. (1995) Effects of nitric oxide on human spermatozoa: evidence that nitric oxide decreases sperm motility and induces sperm toxicity. Human Reproduction 10, 1786 1790.
57. Santoro, G. Romeo, C. (2001) Normal and varicocele testis in adolescents. Asian Journal of Andrology 3, 259 262.
58. Segenreich, E., Shumuely, H. Singer, R. (1986) Andrological parameters in patients with varicoceles and fertility disorders by high ligation of the left spermatic vein. International Journal of Fertility 31, 200 203.
59. Shafick, A., Wali, M. A. AbdelAzis, Y. E. (1989) Experimental model of varicocele. European Urology 16, 298 303.
60. Sharma, R. K. Agarwal, A. (1996) Role of reactive oxygen species in male infertility. Urology 48, 835 850.
61. Sharma, R. K., Pasqualotto, F. F. Nelson, D. R. (1999) The reactive oxygen species-total antioxidant capacity (ROS-TAC) score is a new measure of oxidative stress to predict male infertility. Human Reproduction 14, 2801 2807.
62. Shekarriz, M., Sharma, R. K., Thomas, A. J., Jr. Agarwal, A. (1995) Positive myeloperoxidase staining (Endtz test) as an indicator of excessive reactive oxygen species formation in semen. Journal of Assisted Reproduction and Genetics 12, 70 74.
63. Sorensen, M. B., Bergdahl, I. A., Hjollund, N. H. I., Bonde, J. P. E., Stoltenberg, M. Ernst, E. (1999) Zinc, magnesium and calcium in human seminal fluid: relations to other semen parameters and fertility. Molecular Human Reproduction 5, 331 337.
64. Su, I., Goldstein, M. Schlegel, P. N. (1995) The effects of varicocelectomy on serum testosterone levels in infertile men with varicoceles. The Journal of Urology 154, 1752 1755.
65. Twigg, J., Fulton, N. Gómez, E. (1998) Analysis of the impact of intracellular reactive oxygen species generation on the structural and functional integrity of human spermatozoa: lipid peroxidation, DNA fragmentation and effective antioxidants. Human Reproduction 13, 1429 1436.
66. Verdon, C. P., Burton, B. A. Prior, R. L. (1995) Sample pre-treatment with nitrate reductase and glucose-6-phosphate dehydrogenase quantitatively reduces nitrate while avoiding interference by NADP+ when the Griess reaction is used to assay for nitrite. Analytical Biochemistry 224, 502 508.
67. Wheeler, M. D., Nakagami, M., Bradford, B. U., Uesugi, T., Mason, R. P., Connor, H. D., Dikalova, A., Kadiiska, M. Thurman, R. G. (2001) Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat. Journal of Biological Chemistry 276, 36664 36672.
68. Wild, C. P., Anderson, C., O'Brien, N. M., Wilson, L. Woods, J. A. (2001) A critical evaluation of the application of biomarkers in epidemiological studies on diet and health. British Journal of Nutrition 86, S37 S53.
69. World Health Organization (1999) WHO Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. Cambridge University Press, Cambridge, UK.
70. Xu, D. X., Shen, H. M., Zhu, Q. X., Chua, L., Wang, Q. N., Chia, S. E. Ong, C. N. (2003) The associations among semen quality, oxidative DNA damage in human spermatozoa and concentrations of cadmium, lead, and selenium in seminal plasma. Mutation Research 534, 155 163.
71. Yagi, K. (1976) A simple fluorimetric assay for lipoperoxide in blood plasma. Biochemical Medicine 15, 212 216.