Proton magnetic resonance spectroscopy in youth with severe mood dysregulation

Psychiatry Research - Neuroimaging

Volumn 163, Issue 1, 2008, Pages 30-39

  Dickstein, Daniel P ^a,b,c   van der Veen, Jan Willem ^a   Knopf, Lisa ^a   Towbin, Kenneth E ^a   Pine, Daniel S ^a   Leibenluft, Ellen ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b E P BRADLEY HOSPITAL   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Adolescent; Child; Irritable mood; Magnetic resonance spectroscopy

Indexed keywords

CREATININE; GLUTAMIC ACID; GLUTAMINE; INOSITOL; N ACETYLASPARTIC ACID;

ADULT; AROUSAL; ARTICLE; BIPOLAR DISORDER; CELL ENERGY; CHILD PSYCHIATRY; CHRONIC DISEASE; CLINICAL ARTICLE; COMPUTER MODEL; COMPUTER PROGRAM; CONTROLLED STUDY; DISABILITY; DISEASE SEVERITY; FEMALE; HUMAN; MALE; MENTAL PATIENT; METABOLITE; MOOD DISORDER; NEUROBIOLOGY; NEUROIMAGING; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE SCANNER; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCHOOL CHILD; SEVERE MOOD DYSREGULATION; TEMPORAL LOBE;

ANTIMANIC AGENTS; AROUSAL; ASPARTIC ACID; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BIPOLAR DISORDER; BRAIN MAPPING; CEREBRAL CORTEX; CHRONIC DISEASE; CREATINE; DIAGNOSIS, DIFFERENTIAL; DOMINANCE, CEREBRAL; DOUBLE-BLIND METHOD; GLUTAMINE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INOSITOL; IRRITABLE MOOD; LITHIUM COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; MOOD DISORDERS; PHOSPHOCREATINE;

EID: 43049161272     PISSN: 09254927     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2007.11.006     Document Type: Article

References (51)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders 4th Edition Text Revision (DSM-IV-TR) (2000), APA, Washington, D.C.
2. Berridge M.J., and Irvine R.F. Inositol phosphates and cell signalling. Nature 341 (1989) 197-205
3. Brotman M.A., Schmajuk M., Rich B.A., Dickstein D.P., Guyer A.E., Costello E.J., Egger H.L., Angold A., Pine D.S., and Leibenluft E. Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children. Biological Psychiatry 60 (2006) 991-997
4. Carlson G.A. Mania and ADHD: comorbidity or confusion. Journal of Affective Disorders 51 (1998) 177-187
5. Carrey N., MacMaster F.P., Fogel J., Sparkes S., Waschbusch D., Sullivan S., and Schmidt M. Metabolite changes resulting from treatment in children with ADHD: a 1H-MRS study. Clinical Neuropharmacology 26 (2003) 218-221
6. Carrey N.J., MacMaster F.P., Gaudet L., and Schmidt M.H. Striatal creatine and glutamate/glutamine in attention-deficit/hyperactivity disorder. Journal of Child and Adolescent Psychopharmacology 17 (2007) 11-17
7. Castillo M., Kwock L., Courvoisie H., and Hooper S.R. Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations. American Journal of Neuroradiology 21 (2000) 832-838
8. Cecil K.M., DelBello M.P., Sellars M.C., and Strakowski S.M. Proton magnetic resonance spectroscopy of the frontal lobe and cerebellar vermis in children with a mood disorder and a familial risk for bipolar disorders. Journal of Child and Adolescent Psychopharmacology 13 (2003) 545-555
9. Chang K., Adleman N., Dienes K., Barnea-Goraly N., Reiss A., and Ketter T. Decreased N-acetylaspartate in children with familial bipolar disorder. Biological Psychiatry 53 (2003) 1059-1065
10. Courvoisie H., Hooper S.R., Fine C., Kwock L., and Castillo M. Neurometabolic functioning and neuropsychological correlates in children with ADHD-H: preliminary findings. Journal of Neuropsychiatry and Clinical Neurosciences 16 (2004) 63-69
11. Davanzo P., Thomas M.A., Yue K., Oshiro T., Belin T., Strober M., and McCracken J. Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder. Neuropsychopharmacology 24 (2001) 359-369
12. Davanzo P., Yue K., Thomas M.A., Belin T., Mintz J., Venkatraman T.N., Santoro E., Barnett S., and McCracken J. Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents. American Journal of Psychiatry 160 (2003) 1442-1452
13. DelBello M.P., Cecil K.M., Adler C.M., Daniels J.P., and Strakowski S.M. Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study. Neuropsychopharmacology 31 (2006) 1264-1273
14. Dickstein D.P., Rich B.A., Binstock A.B., Pradella A.G., Towbin K.E., Pine D.S., and Leibenluft E. Comorbid anxiety in phenotypes of pediatric bipolar disorder. Journal of Child and Adolescent Psychopharmacology 15 (2005) 534-548
15. Dickstein D.P., Nelson E.E., McClure E.B., Grimley M.E., Knopf L., Brotman M.A., Rich B.A., Pine D.S., and Leibenluft E. Cognitive flexibility in phenotypes of pediatric bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry 46 (2007) 341-355
16. Emslie G.J., Weinberg W.A., Rush A.J., Adams R.M., and Rintelmann J.W. Depressive symptoms by self-report in adolescence: phase I of the development of a questionnaire for depression by self-report. Journal of Child Neurology 5 (1990) 114-121
17. Farchione T.R., Moore G.J., and Rosenberg D.R. Proton magnetic resonance spectroscopic imaging in pediatric major depression. Biological Psychiatry 52 (2002) 86-92
18. Gasparovic C., Song T., Devier D., Bockholt H.J., Caprihan A., Mullins P.G., Posse S., Jung R.E., and Morrison L.A. Use of tissue water as a concentration reference for proton spectroscopic imaging. Magnetic Resonance in Medicine 55 (2006) 1219-1226
19. Geller B., Williams M., Zimerman B., Frazier J., Beringer L., and Warner K.L. Prepubertal and early adolescent bipolarity differentiate from ADHD by manic symptoms, grandiose delusions, ultra-rapid or ultradian cycling. Journal of Affective Disorders 51 (1998) 81-91
20. Gould T.D., Quiroz J.A., Singh J., Zarate C.A., and Manji H.K. Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Molecular Psychiatry 9 (2004) 734-755
21. Hancu I., Blezek D.J., and Dumoulin M.C. Automatic repositioning of single voxels in longitudinal 1H MRS studies. NMR in Biomedicine 18 (2005) 352-361
22. Kaufman J., Birmaher B., Brent D., Rao U., Flynn C., Moreci P., Williamson D., and Ryan N. Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry 36 (1997) 980-988
23. Komoroski R.A., Kotrla K.J., Lemen L., Lindquist D., Diaz P., and Foundas A. Brain metabolite concentration ratios in vivo: multisite reproducibility by single-voxel 1H MR spectroscopy. Magnetic Resonance Imaging 22 (2004) 721-725
24. Leckman J.F., Sholomskas D., Thompson W.D., Belanger A., and Weissman M.M. Best estimate of lifetime psychiatric diagnosis: a methodological study. Archives of General Psychiatry 39 (1982) 879-883
25. Leibenluft E., Charney D.S., Towbin K.E., Bhangoo R.K., and Pine D.S. Defining clinical phenotypes of juvenile mania. American Journal of Psychiatry 160 (2003) 430-437
26. Lenroot R.K., Gogtay N., Greenstein D.K., Wells E.M., Wallace G.L., Clasen L.S., Blumenthal J.D., Lerch J., Zijdenbos A.P., Evans A.C., Thompson P.M., and Giedd J.N. Sexual dimorphism of brain developmental trajectories during childhood and adolescence. Neuroimage 36 (2007) 1065-1073
27. MacMaster F.P., Carrey N., Sparkes S., and Kusumakar V. Proton spectroscopy in medication-free pediatric attention-deficit/hyperactivity disorder. Biological Psychiatry 53 (2003) 184-187
28. Mirza Y., Tang J., Russell A., Banerjee S.P., Bhandari R., Ivey J., Rose M., Moore G.J., and Rosenberg D.R. Reduced anterior cingulate cortex glutamatergic concentrations in childhood major depression. Journal of the American Academy of Child and Adolescent Psychiatry 43 (2004) 341-348
29. Moore G.J., Bebchuk J.M., Parrish J.K., Faulk M.W., Arfken C.L., Strahl-Bevacqua J., and Manji H.K. Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness. American Journal of Psychiatry 156 (1999) 1902-1908
30. Moore G.J., Bebchuk J.M., Hasanat K., Chen G., Seraji-Bozorgzad N., Wilds I.B., Faulk M.W., Koch S., Glitz D.A., Jolkovsky L., and Manji H.K. Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?. Biological Psychiatry 48 (2000) 1-8
31. Moore C.M., Biederman J., Wozniak J., Mick E., Aleardi M., Wardrop M., Dougherty M., Harpold T., Hammerness P., Randall E., and Renshaw P.F. Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study. American Journal of Psychiatry 163 (2006) 316-318
32. NIMH. National Institute of Mental Health research roundtable on prepubertal bipolar disorder. Journal of the American Academy of Child and Adolescent Psychiatry 40 (2001) 871-878
33. O'Donnell T., Rotzinger S., Nakashima T.T., Hanstock C.C., Ulrich M., and Silverstone P.H. Chronic lithium and sodium valproate both decrease the concentration of myoinositol and increase the concentration of inositol monophosphates in rat brain. European Neuropsychopharmacology 13 (2003) 199-207
34. Patel N.C., DelBello M.P., Cecil K.M., Adler C.M., Bryan H.S., Stanford K.E., and Strakowski S.M. Lithium treatment effects on myo-inositol in adolescents with bipolar depression. Biological Psychiatry 60 (2006) 998-1004
35. Pogge D.L., Wayland-Smith D., Zaccario M., Borgaro S., Stokes J., and Harvey P.D. Diagnosis of manic episodes in adolescent inpatients: structured diagnostic procedures compared to clinical chart diagnoses. Psychiatry Research 101 (2001) 47-54
36. Provencher S.W. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magnetic Resonance in Medicine 30 (1993) 672-679
37. Reich W., Neuman R.J., Volk H.E., Joyner C.A., and Todd R.D. Comorbidity between ADHD and symptoms of bipolar disorder in a community sample of children and adolescents. Twin Research and Human Genetics 8 (2005) 459-466
38. Rich B.A., Schmajuk M., Perez-Edgar K.E., Fox N.A., Pine D.S., and Leibenluft E. Different psychophysiological and behavioral responses elicited by frustration in pediatric bipolar disorder and severe mood dysregulation. American Journal of Psychiatry 164 (2007) 309-317
39. Rosenberg D.R., MacMaster F.P., Mirza Y., Smith J.M., Easter P.C., Banerjee S.P., Bhandari R., Boyd C., Lynch M., Rose M., Ivey J., Villafuerte R.A., Moore G.J., and Renshaw P. Reduced anterior cingulate glutamate in pediatric major depression: a magnetic resonance spectroscopy study. Biological Psychiatry 58 (2005) 700-704
40. Sassi R.B., Stanley J.A., Axelson D., Brambilla P., Nicoletti M.A., Keshavan M.S., Ramos R.T., Ryan N., Birmaher B., and Soares J.C. Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients. American Journal of Psychiatry 162 (2005) 2109-2115
41. Shaffer D., Gould M.S., Brasic J., Ambrosini P., Fisher P., Bird H., and Aluwahlia S. A children's global assessment scale (CGAS). Archives of General Psychiatry 40 (1983) 1228-1231
42. Silverstone P.H., Hanstock C.C., Fabian J., Staab R., and Allen P.S. Chronic lithium does not alter human myo-inositol or phosphomonoester concentrations as measured by 1H and 31P MRS. Biological Psychiatry 40 (1996) 235-246
43. Silverstone P.H., McGrath B.M., and Kim H. Bipolar disorder and myo-inositol: a review of the magnetic resonance spectroscopy findings. Bipolar Disorders 7 (2005) 1-10
44. Silverstone P.H., O'Donnell T., Ulrich M., Asghar S., and Hanstock C.C. Dextro-amphetamine increases phosphoinositol cycle activity in volunteers: an MRS study. Human Psychopharmacology 17 (2002) 425-429
45. Silverstone P.H., Wu R.H., O'Donnell T., Ulrich M., Asghar S.J., and Hanstock C.C. Chronic treatment with both lithium and sodium valproate may normalize phosphoinositol cycle activity in bipolar patients. Human Psychopharmacology 17 (2002) 321-327
46. Silverstone P.H., Wu R.H., O'Donnell T., Ulrich M., Asghar S.J., and Hanstock C.C. Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients. International Clinical Psychopharmacology 18 (2003) 73-79
47. Stork C., and Renshaw P.F. Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research. Molecular Psychiatry 10 (2005) 900-919
48. Tsai G., and Coyle J.T. N-acetylaspartate in neuropsychiatric disorders. Progress in Neurobiology 46 (1995) 531-540
49. Werry J.S., Sprague R.L., and Cohen M.N. Conners' Teacher Rating Scale for use in drug studies with children-an empirical study. Journal of Abnormal Child Psychology 3 (1975) 217-229
50. Young R.C., Biggs J.T., Ziegler V.E., and Meyer D.A. A rating scale for mania: reliability, validity and sensitivity. British Journal of Psychiatry 133 (1978) 429-435
51. Zarate C.A., Quiroz J., Payne J., and Manji H.K. Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders. Psychopharmacology Bulletin 36 (2002) 35-83