-
1
-
-
0842281643
-
Mammalian prion biology: one century of evolving concepts
-
Aguzzi A., and Polymenidou M. Mammalian prion biology: one century of evolving concepts. Cell 116 (2004) 313-327
-
(2004)
Cell
, vol.116
, pp. 313-327
-
-
Aguzzi, A.1
Polymenidou, M.2
-
3
-
-
0036838213
-
Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles
-
Baker C.A., Martin D., and Manuelidis L. Microglia from Creutzfeldt-Jakob disease-infected brains are infectious and show specific mRNA activation profiles. J. Virol. 76 (2002) 10905-10913
-
(2002)
J. Virol.
, vol.76
, pp. 10905-10913
-
-
Baker, C.A.1
Martin, D.2
Manuelidis, L.3
-
4
-
-
33144469836
-
Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res
-
Baron G.S., Magalhaes A.C., Prado M.A., and Caughey B. Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res. J. Virol. 80 (2006) 2106-2117
-
(2006)
J. Virol.
, vol.80
, pp. 2106-2117
-
-
Baron, G.S.1
Magalhaes, A.C.2
Prado, M.A.3
Caughey, B.4
-
5
-
-
0026567814
-
Nearly ubiquitous tissue distribution of the scrapie agent precursor protein
-
Bendheim P.E., Brown H.R., Rudelli R.D., Scala L.J., Goller N.L., Wen G.Y., Kascsak R.J., Cashman N.R., and Bolton D.C. Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology 42 (1992) 149-156
-
(1992)
Neurology
, vol.42
, pp. 149-156
-
-
Bendheim, P.E.1
Brown, H.R.2
Rudelli, R.D.3
Scala, L.J.4
Goller, N.L.5
Wen, G.Y.6
Kascsak, R.J.7
Cashman, N.R.8
Bolton, D.C.9
-
6
-
-
0035796463
-
Scrapie strains maintain biological phenotypes on propagation in a cell line in culture
-
Birkett C.R., Hennion R.M., Bembridge D.A., Clarke M.C., Chree A., Bruce M.E., and Bostock C.J. Scrapie strains maintain biological phenotypes on propagation in a cell line in culture. EMBO J. 20 (2001) 3351-3358
-
(2001)
EMBO J.
, vol.20
, pp. 3351-3358
-
-
Birkett, C.R.1
Hennion, R.M.2
Bembridge, D.A.3
Clarke, M.C.4
Chree, A.5
Bruce, M.E.6
Bostock, C.J.7
-
7
-
-
0025304678
-
Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells
-
Borchelt D.R., Scott M., Taraboulos A., Stahl N., and Prusiner S.B. Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. J. Cell Biol. 110 (1990) 743-752
-
(1990)
J. Cell Biol.
, vol.110
, pp. 743-752
-
-
Borchelt, D.R.1
Scott, M.2
Taraboulos, A.3
Stahl, N.4
Prusiner, S.B.5
-
8
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
Bueler H., Aguzzi A., Sailer A., Greiner R.A., Autenried P., Aguet M., and Weissmann C. Mice devoid of PrP are resistant to scrapie. Cell 73 (1993) 1339-1347
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Bueler, H.1
Aguzzi, A.2
Sailer, A.3
Greiner, R.A.4
Autenried, P.5
Aguet, M.6
Weissmann, C.7
-
9
-
-
0023928927
-
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins
-
Butler D.A., Scott M.R., Bockman J.M., Borchelt D.R., Taraboulos A., Hsiao K.K., Kingsbury D.T., and Prusiner S.B. Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins. J. Virol. 62 (1988) 1558-1564
-
(1988)
J. Virol.
, vol.62
, pp. 1558-1564
-
-
Butler, D.A.1
Scott, M.R.2
Bockman, J.M.3
Borchelt, D.R.4
Taraboulos, A.5
Hsiao, K.K.6
Kingsbury, D.T.7
Prusiner, S.B.8
-
10
-
-
0028361162
-
Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation
-
Cirulli V., Baetens D., Rutishauser U., Halban P.A., Orci L., and Rouiller D.G. Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation. J. Cell Sci. 107 (1994) 1429-1436
-
(1994)
J. Cell Sci.
, vol.107
, pp. 1429-1436
-
-
Cirulli, V.1
Baetens, D.2
Rutishauser, U.3
Halban, P.A.4
Orci, L.5
Rouiller, D.G.6
-
11
-
-
0027270578
-
A kinetic model for amyloid formation in the prion diseases: importance of seeding
-
Come J.H., Fraser P.E., and Lansbury Jr. P.T. A kinetic model for amyloid formation in the prion diseases: importance of seeding. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 5959-5963
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 5959-5963
-
-
Come, J.H.1
Fraser, P.E.2
Lansbury Jr., P.T.3
-
12
-
-
0038783253
-
Specific inhibition of pathological prion protein accumulation by small interfering RNAs
-
Daude N., Marella M., and Chabry J. Specific inhibition of pathological prion protein accumulation by small interfering RNAs. J. Cell Sci. 116 (2003) 2775-2779
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2775-2779
-
-
Daude, N.1
Marella, M.2
Chabry, J.3
-
13
-
-
0025783174
-
Glucose induces insulin gene transcription in a murine pancreatic beta-cell line
-
Efrat S., Surana M., and Fleischer N. Glucose induces insulin gene transcription in a murine pancreatic beta-cell line. J. Biol. Chem. 266 (1991) 11141-11143
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11141-11143
-
-
Efrat, S.1
Surana, M.2
Fleischer, N.3
-
14
-
-
0035979274
-
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
-
Enari M., Flechsig E., and Weissmann C. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 9295-9299
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 9295-9299
-
-
Enari, M.1
Flechsig, E.2
Weissmann, C.3
-
15
-
-
4744361580
-
The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells
-
Ertmer A., Gilch S., Yun S.W., Flechsig E., Klebl B., Stein-Gerlach M., Klein M.A., and Schatzl H.M. The tyrosine kinase inhibitor STI571 induces cellular clearance of PrPSc in prion-infected cells. J. Biol. Chem. 279 (2004) 41918-41927
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41918-41927
-
-
Ertmer, A.1
Gilch, S.2
Yun, S.W.3
Flechsig, E.4
Klebl, B.5
Stein-Gerlach, M.6
Klein, M.A.7
Schatzl, H.M.8
-
16
-
-
0029781211
-
Protease-resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy
-
Farquhar C.F., Dornan J., Moore R.C., Somerville R.A., Tunstall A.M., and Hope J. Protease-resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy. J. Gen. Virol. 77 Pt 8 (1996) 1941-1946
-
(1996)
J. Gen. Virol.
, vol.77
, Issue.PART 8
, pp. 1941-1946
-
-
Farquhar, C.F.1
Dornan, J.2
Moore, R.C.3
Somerville, R.A.4
Tunstall, A.M.5
Hope, J.6
-
17
-
-
0036020722
-
Localization of neural cell adhesion molecule (N-CAM) immunoreactivity in adult rat tissues
-
Filiz S., Dalcik H., Yardimoglu M., Gonca S., and Ceylan S. Localization of neural cell adhesion molecule (N-CAM) immunoreactivity in adult rat tissues. Biotech. Histochem. 77 (2002) 127-135
-
(2002)
Biotech. Histochem.
, vol.77
, pp. 127-135
-
-
Filiz, S.1
Dalcik, H.2
Yardimoglu, M.3
Gonca, S.4
Ceylan, S.5
-
18
-
-
17844392850
-
Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease
-
Gilch S., Winklhofer K.F., Groschup M.H., Nunziante M., Lucassen R., Spielhaupter C., Muranyi W., Riesner D., Tatzelt J., and Schatzl H.M. Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease. EMBO J. 20 (2001) 3957-3966
-
(2001)
EMBO J.
, vol.20
, pp. 3957-3966
-
-
Gilch, S.1
Winklhofer, K.F.2
Groschup, M.H.3
Nunziante, M.4
Lucassen, R.5
Spielhaupter, C.6
Muranyi, W.7
Riesner, D.8
Tatzelt, J.9
Schatzl, H.M.10
-
19
-
-
0037705352
-
Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells
-
Gilch S., Wopfner F., Renner-Muller I., Kremmer E., Bauer C., Wolf E., Brem G., Groschup M.H., and Schatzl H.M. Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells. J. Biol. Chem. 278 (2003) 18524-18531
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18524-18531
-
-
Gilch, S.1
Wopfner, F.2
Renner-Muller, I.3
Kremmer, E.4
Bauer, C.5
Wolf, E.6
Brem, G.7
Groschup, M.H.8
Schatzl, H.M.9
-
20
-
-
33644850940
-
Prion infection of mouse neurospheres
-
Giri R.K., Young R., Pitstick R., DeArmond S.J., Prusiner S.B., and Carlson G.A. Prion infection of mouse neurospheres. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 3875-3880
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 3875-3880
-
-
Giri, R.K.1
Young, R.2
Pitstick, R.3
DeArmond, S.J.4
Prusiner, S.B.5
Carlson, G.A.6
-
21
-
-
0242361687
-
Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease
-
Glatzel M., Abela E., Maissen M., and Aguzzi A. Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease. N. Engl. J. Med. 349 (2003) 1812-1820
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 1812-1820
-
-
Glatzel, M.1
Abela, E.2
Maissen, M.3
Aguzzi, A.4
-
22
-
-
21144437395
-
Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells
-
Greenwood A.D., Horsch M., Stengel A., Vorberg I., Lutzny G., Maas E., Schadler S., Erfle V., Beckers J., Schatzl H., and Leib-Mosch C. Cell line dependent RNA expression profiles of prion-infected mouse neuronal cells. J. Mol. Biol. 349 (2005) 487-500
-
(2005)
J. Mol. Biol.
, vol.349
, pp. 487-500
-
-
Greenwood, A.D.1
Horsch, M.2
Stengel, A.3
Vorberg, I.4
Lutzny, G.5
Maas, E.6
Schadler, S.7
Erfle, V.8
Beckers, J.9
Schatzl, H.10
Leib-Mosch, C.11
-
23
-
-
13844259181
-
Chronic lymphocytic inflammation specifies the organ tropism of prions
-
Heikenwalder M., Zeller N., Seeger H., Prinz M., Klohn P.C., Schwarz P., Ruddle N.H., Weissmann C., and Aguzzi A. Chronic lymphocytic inflammation specifies the organ tropism of prions. Science 307 (2005) 1107-1110
-
(2005)
Science
, vol.307
, pp. 1107-1110
-
-
Heikenwalder, M.1
Zeller, N.2
Seeger, H.3
Prinz, M.4
Klohn, P.C.5
Schwarz, P.6
Ruddle, N.H.7
Weissmann, C.8
Aguzzi, A.9
-
24
-
-
38449092370
-
Polylactide-coglycolide microspheres co-encapsulating recombinant tandem prion protein with CpG-oligonucleotide break self-tolerance to prion protein in wild-type mice and induce CD4 and CD8 T cell responses
-
Kaiser-Schulz G., Heit A., Quintanilla-Martinez L., Hammerschmidt F., Hess S., Jennen L., Rezaei H., Wagner H., and Schatzl H.M. Polylactide-coglycolide microspheres co-encapsulating recombinant tandem prion protein with CpG-oligonucleotide break self-tolerance to prion protein in wild-type mice and induce CD4 and CD8 T cell responses. J. Immunol. 179 (2007) 2797-2807
-
(2007)
J. Immunol.
, vol.179
, pp. 2797-2807
-
-
Kaiser-Schulz, G.1
Heit, A.2
Quintanilla-Martinez, L.3
Hammerschmidt, F.4
Hess, S.5
Jennen, L.6
Rezaei, H.7
Wagner, H.8
Schatzl, H.M.9
-
25
-
-
40449095371
-
Prion protein/protein interactions: fusion with yeast Sup35p-NM modulates cytosolic PrP aggregation in mammalian cells
-
Krammer C., Suhre M.H., Kremmer E., Diemer C., Hess S., Schatzl H.M., Scheibel T., and Vorberg I. Prion protein/protein interactions: fusion with yeast Sup35p-NM modulates cytosolic PrP aggregation in mammalian cells. FASEB J. 22 (2008) 762-773
-
(2008)
FASEB J.
, vol.22
, pp. 762-773
-
-
Krammer, C.1
Suhre, M.H.2
Kremmer, E.3
Diemer, C.4
Hess, S.5
Schatzl, H.M.6
Scheibel, T.7
Vorberg, I.8
-
27
-
-
0034708049
-
Enhanced expression of cellular prion protein gene by insulin or nerve growth factor in immortalized mouse neuronal precursor cell lines
-
Kuwahara C., Kubosaki A., Nishimura T., Nasu Y., Nakamura Y., Saeki K., Matsumoto Y., and Onodera T. Enhanced expression of cellular prion protein gene by insulin or nerve growth factor in immortalized mouse neuronal precursor cell lines. Biochem. Biophys. Res. Commun. 268 (2000) 763-766
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.268
, pp. 763-766
-
-
Kuwahara, C.1
Kubosaki, A.2
Nishimura, T.3
Nasu, Y.4
Nakamura, Y.5
Saeki, K.6
Matsumoto, Y.7
Onodera, T.8
-
28
-
-
0028031771
-
Modulation of prion protein gene expression by growth factors in cultured mouse astrocytes and PC-12 cells
-
Lazarini F., Castelnau P., Chermann J.F., Deslys J.P., and Dormont D. Modulation of prion protein gene expression by growth factors in cultured mouse astrocytes and PC-12 cells. Brain Res. Mol. Brain Res. 22 (1994) 268-274
-
(1994)
Brain Res. Mol. Brain Res.
, vol.22
, pp. 268-274
-
-
Lazarini, F.1
Castelnau, P.2
Chermann, J.F.3
Deslys, J.P.4
Dormont, D.5
-
29
-
-
33646105873
-
Overexpression of PrPC and its antiapoptosis function in gastric cancer
-
Liang J., Pan Y.L., Ning X.X., Sun L.J., Lan M., Hong L., Du J.P., Liu N., Liu C.J., Qiao T.D., and Fan D.M. Overexpression of PrPC and its antiapoptosis function in gastric cancer. Tumour Biol. 27 (2006) 84-91
-
(2006)
Tumour Biol.
, vol.27
, pp. 84-91
-
-
Liang, J.1
Pan, Y.L.2
Ning, X.X.3
Sun, L.J.4
Lan, M.5
Hong, L.6
Du, J.P.7
Liu, N.8
Liu, C.J.9
Qiao, T.D.10
Fan, D.M.11
-
30
-
-
30744466152
-
PrPSc in mammary glands of sheep affected by scrapie and mastitis
-
Ligios C., Sigurdson C.J., Santucciu C., Carcassola G., Manco G., Basagni M., Maestrale C., Cancedda M.G., Madau L., and Aguzzi A. PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nat. Med. 11 (2005) 1137-1138
-
(2005)
Nat. Med.
, vol.11
, pp. 1137-1138
-
-
Ligios, C.1
Sigurdson, C.J.2
Santucciu, C.3
Carcassola, G.4
Manco, G.5
Basagni, M.6
Maestrale, C.7
Cancedda, M.G.8
Madau, L.9
Aguzzi, A.10
-
31
-
-
0034904789
-
Cellular prion protein status in sheep: tissue-specific biochemical signatures
-
Moudjou M., Frobert Y., Grassi J., and La Bonnardiere C. Cellular prion protein status in sheep: tissue-specific biochemical signatures. J. Gen. Virol. 82 (2001) 2017-2024
-
(2001)
J. Gen. Virol.
, vol.82
, pp. 2017-2024
-
-
Moudjou, M.1
Frobert, Y.2
Grassi, J.3
La Bonnardiere, C.4
-
32
-
-
0032533443
-
Expression of non-classical islet hormone-like peptides during the embryonic development of the pancreas
-
Mulder H., Myrsen-Axcrona U., Gebre-Medhin S., Ekblad E., and Sundler F. Expression of non-classical islet hormone-like peptides during the embryonic development of the pancreas. Microsc. Res. Tech. 43 (1998) 313-321
-
(1998)
Microsc. Res. Tech.
, vol.43
, pp. 313-321
-
-
Mulder, H.1
Myrsen-Axcrona, U.2
Gebre-Medhin, S.3
Ekblad, E.4
Sundler, F.5
-
33
-
-
13244255633
-
Prion-associated increases in Src-family kinases
-
Nixon R.R. Prion-associated increases in Src-family kinases. J. Biol. Chem. 280 (2005) 2455-2462
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2455-2462
-
-
Nixon, R.R.1
-
34
-
-
0347992944
-
Prion diseases: from molecular biology to intervention strategies
-
Nunziante M., Gilch S., and Schatzl H.M. Prion diseases: from molecular biology to intervention strategies. ChemBioChem 4 (2003) 1268-1284
-
(2003)
ChemBioChem
, vol.4
, pp. 1268-1284
-
-
Nunziante, M.1
Gilch, S.2
Schatzl, H.M.3
-
35
-
-
0035965247
-
Up-regulation of functionally impaired insulin-like growth factor-1 receptor in scrapie-infected neuroblastoma cells
-
Ostlund P., Lindegren H., Pettersson C., and Bedecs K. Up-regulation of functionally impaired insulin-like growth factor-1 receptor in scrapie-infected neuroblastoma cells. J. Biol. Chem. 276 (2001) 36110-36115
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36110-36115
-
-
Ostlund, P.1
Lindegren, H.2
Pettersson, C.3
Bedecs, K.4
-
36
-
-
1942519718
-
Anti-PrP antibodies block PrPSc replication in prion-infected cell cultures by accelerating PrPC degradation
-
Perrier V., Solassol J., Crozet C., Frobert Y., Mourton-Gilles C., Grassi J., and Lehmann S. Anti-PrP antibodies block PrPSc replication in prion-infected cell cultures by accelerating PrPC degradation. J. Neurochem. 89 (2004) 454-463
-
(2004)
J. Neurochem.
, vol.89
, pp. 454-463
-
-
Perrier, V.1
Solassol, J.2
Crozet, C.3
Frobert, Y.4
Mourton-Gilles, C.5
Grassi, J.6
Lehmann, S.7
-
38
-
-
0025244011
-
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
-
Prusiner S.B., Scott M., Foster D., Pan K.M., Groth D., Mirenda C., Torchia M., Yang S.L., Serban D., and Carlson G.A. Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell 63 (1990) 673-686
-
(1990)
Cell
, vol.63
, pp. 673-686
-
-
Prusiner, S.B.1
Scott, M.2
Foster, D.3
Pan, K.M.4
Groth, D.5
Mirenda, C.6
Torchia, M.7
Yang, S.L.8
Serban, D.9
Carlson, G.A.10
-
39
-
-
0344211494
-
Organ distribution of prion proteins in variant Creutzfeldt-Jakob disease
-
Ramasamy I., Law M., Collins S., and Brooke F. Organ distribution of prion proteins in variant Creutzfeldt-Jakob disease. Lancet, Infect. Dis. 3 (2003) 214-222
-
(2003)
Lancet, Infect. Dis.
, vol.3
, pp. 214-222
-
-
Ramasamy, I.1
Law, M.2
Collins, S.3
Brooke, F.4
-
40
-
-
0021745705
-
In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells
-
Rubenstein R., Carp R.I., and Callahan S.M. In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells. J. Gen. Virol. 65 Pt 12 (1984) 2191-2198
-
(1984)
J. Gen. Virol.
, vol.65
, Issue.PART 12
, pp. 2191-2198
-
-
Rubenstein, R.1
Carp, R.I.2
Callahan, S.M.3
-
41
-
-
0025359710
-
Further characterization of scrapie replication in PC12 cells
-
Rubenstein R., Scalici C.L., Papini M.C., Callahan S.M., and Carp R.I. Further characterization of scrapie replication in PC12 cells. J. Gen. Virol. 71 Pt 4 (1990) 825-831
-
(1990)
J. Gen. Virol.
, vol.71
, Issue.PART 4
, pp. 825-831
-
-
Rubenstein, R.1
Scalici, C.L.2
Papini, M.C.3
Callahan, S.M.4
Carp, R.I.5
-
42
-
-
0028421371
-
Scrapie strain infection in vitro induces changes in neuronal cells
-
Rubenstein R., Deng H., Race R., Ju W., Scalici C., Papini M., Rubenstein A., Kascsak R., and Carp R. Scrapie strain infection in vitro induces changes in neuronal cells. Mol. Neurobiol. 8 (1994) 129-138
-
(1994)
Mol. Neurobiol.
, vol.8
, pp. 129-138
-
-
Rubenstein, R.1
Deng, H.2
Race, R.3
Ju, W.4
Scalici, C.5
Papini, M.6
Rubenstein, A.7
Kascsak, R.8
Carp, R.9
-
43
-
-
0037611374
-
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
-
Schatzl H.M., Laszlo L., Holtzman D.M., Tatzelt J., DeArmond S.J., Weiner R.I., Mobley W.C., and Prusiner S.B. A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. J. Virol. 71 (1997) 8821-8831
-
(1997)
J. Virol.
, vol.71
, pp. 8821-8831
-
-
Schatzl, H.M.1
Laszlo, L.2
Holtzman, D.M.3
Tatzelt, J.4
DeArmond, S.J.5
Weiner, R.I.6
Mobley, W.C.7
Prusiner, S.B.8
-
44
-
-
34548392742
-
In vitro and in vivo neurotoxicity of prion protein oligomers
-
Simoneau S., Rezaei H., Sales N., Kaiser-Schulz G., Lefebvre-Roque M., Vidal C., Fournier J.G., Comte J., Wopfner F., Grosclaude J., Schatzl H., and Lasmezas C.I. In vitro and in vivo neurotoxicity of prion protein oligomers. PLoS Pathog. 3 (2007) e125
-
(2007)
PLoS Pathog.
, vol.3
-
-
Simoneau, S.1
Rezaei, H.2
Sales, N.3
Kaiser-Schulz, G.4
Lefebvre-Roque, M.5
Vidal, C.6
Fournier, J.G.7
Comte, J.8
Wopfner, F.9
Grosclaude, J.10
Schatzl, H.11
Lasmezas, C.I.12
-
45
-
-
0036733578
-
Cholesterol, lipid rafts, and disease
-
Simons K., and Ehehalt R. Cholesterol, lipid rafts, and disease. J. Clin. Invest. 110 (2002) 597-603
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 597-603
-
-
Simons, K.1
Ehehalt, R.2
-
46
-
-
0035977053
-
PrPC directly interacts with proteins involved in signaling pathways
-
Spielhaupter C., and Schatzl H.M. PrPC directly interacts with proteins involved in signaling pathways. J. Biol. Chem. 276 (2001) 44604-44612
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44604-44612
-
-
Spielhaupter, C.1
Schatzl, H.M.2
-
47
-
-
33847232980
-
Pronounced cytosolic aggregation of cellular prion protein in pancreatic beta-cells in response to hyperglycemia
-
Strom A., Wang G.S., Reimer R., Finegood D.T., and Scott F.W. Pronounced cytosolic aggregation of cellular prion protein in pancreatic beta-cells in response to hyperglycemia. Lab. Invest. 87 (2007) 139-149
-
(2007)
Lab. Invest.
, vol.87
, pp. 139-149
-
-
Strom, A.1
Wang, G.S.2
Reimer, R.3
Finegood, D.T.4
Scott, F.W.5
-
48
-
-
0028966735
-
Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform
-
Taraboulos A., Scott M., Semenov A., Avrahami D., Laszlo L., and Prusiner S.B. Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. J. Cell Biol. 129 (1995) 121-132
-
(1995)
J. Cell Biol.
, vol.129
, pp. 121-132
-
-
Taraboulos, A.1
Scott, M.2
Semenov, A.3
Avrahami, D.4
Laszlo, L.5
Prusiner, S.B.6
-
49
-
-
33846456964
-
Molecular basis of cerebral neurodegeneration in prion diseases
-
Tatzelt J., and Schatzl H.M. Molecular basis of cerebral neurodegeneration in prion diseases. FEBS J. 274 (2007) 606-611
-
(2007)
FEBS J.
, vol.274
, pp. 606-611
-
-
Tatzelt, J.1
Schatzl, H.M.2
-
50
-
-
0038578675
-
Efficient and specific down-regulation of prion protein expression by RNAi
-
Tilly G., Chapuis J., Vilette D., Laude H., and Vilotte J.L. Efficient and specific down-regulation of prion protein expression by RNAi. Biochem. Biophys. Res. Commun. 305 (2003) 548-551
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.305
, pp. 548-551
-
-
Tilly, G.1
Chapuis, J.2
Vilette, D.3
Laude, H.4
Vilotte, J.L.5
-
51
-
-
27844578208
-
KDEL-tagged anti-prion intrabodies impair PrP lysosomal degradation and inhibit scrapie infectivity
-
Vetrugno V., Cardinale A., Filesi I., Mattei S., Sy M.S., Pocchiari M., and Biocca S. KDEL-tagged anti-prion intrabodies impair PrP lysosomal degradation and inhibit scrapie infectivity. Biochem. Biophys. Res. Commun. 338 (2005) 1791-1797
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.338
, pp. 1791-1797
-
-
Vetrugno, V.1
Cardinale, A.2
Filesi, I.3
Mattei, S.4
Sy, M.S.5
Pocchiari, M.6
Biocca, S.7
-
52
-
-
0035957345
-
Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein
-
Vilette D., Andreoletti O., Archer F., Madelaine M.F., Vilotte J.L., Lehmann S., and Laude H. Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 4055-4059
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4055-4059
-
-
Vilette, D.1
Andreoletti, O.2
Archer, F.3
Madelaine, M.F.4
Vilotte, J.L.5
Lehmann, S.6
Laude, H.7
-
53
-
-
3142726518
-
Acute formation of protease-resistant prion protein does not always lead to persistent scrapie infection in vitro
-
Vorberg I., Raines A., and Priola S.A. Acute formation of protease-resistant prion protein does not always lead to persistent scrapie infection in vitro. J. Biol. Chem. 279 (2004) 29218-29225
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29218-29225
-
-
Vorberg, I.1
Raines, A.2
Priola, S.A.3
-
54
-
-
1142285202
-
Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents
-
Vorberg I., Raines A., Story B., and Priola S.A. Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents. J. Infect. Dis. 189 (2004) 431-439
-
(2004)
J. Infect. Dis.
, vol.189
, pp. 431-439
-
-
Vorberg, I.1
Raines, A.2
Story, B.3
Priola, S.A.4
-
55
-
-
0035928432
-
Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay
-
Wadsworth J.D., Joiner S., Hill A.F., Campbell T.A., Desbruslais M., Luthert P.J., and Collinge J. Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay. Lancet 358 (2001) 171-180
-
(2001)
Lancet
, vol.358
, pp. 171-180
-
-
Wadsworth, J.D.1
Joiner, S.2
Hill, A.F.3
Campbell, T.A.4
Desbruslais, M.5
Luthert, P.J.6
Collinge, J.7
-
58
-
-
33646695909
-
Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury
-
Weise J., Sandau R., Schwarting S., Crome O., Wrede A., Schulz-Schaeffer W., Zerr I., and Bahr M. Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury. Stroke 37 (2006) 1296-1300
-
(2006)
Stroke
, vol.37
, pp. 1296-1300
-
-
Weise, J.1
Sandau, R.2
Schwarting, S.3
Crome, O.4
Wrede, A.5
Schulz-Schaeffer, W.6
Zerr, I.7
Bahr, M.8
-
59
-
-
0029130074
-
Molecular biology of transmissible spongiform encephalopathies
-
Weissmann C. Molecular biology of transmissible spongiform encephalopathies. Prog. Brain Res. 105 (1995) 15-22
-
(1995)
Prog. Brain Res.
, vol.105
, pp. 15-22
-
-
Weissmann, C.1
-
60
-
-
0037133587
-
Structural studies of the scrapie prion protein by electron crystallography
-
Wille H., Michelitsch M.D., Guenebaut V., Supattapone S., Serban A., Cohen F.E., Agard D.A., and Prusiner S.B. Structural studies of the scrapie prion protein by electron crystallography. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 3563-3568
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 3563-3568
-
-
Wille, H.1
Michelitsch, M.D.2
Guenebaut, V.3
Supattapone, S.4
Serban, A.5
Cohen, F.E.6
Agard, D.A.7
Prusiner, S.B.8
-
61
-
-
0029794668
-
Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release
-
Wong K., Qiu Y., Hyun W., Nixon R., VanCleff J., Sanchez-Salazar J., Prusiner S.B., and DeArmond S.J. Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release. Neurology 47 (1996) 741-750
-
(1996)
Neurology
, vol.47
, pp. 741-750
-
-
Wong, K.1
Qiu, Y.2
Hyun, W.3
Nixon, R.4
VanCleff, J.5
Sanchez-Salazar, J.6
Prusiner, S.B.7
DeArmond, S.J.8
-
62
-
-
4644251530
-
Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology
-
Xiang W., Windl O., Wunsch G., Dugas M., Kohlmann A., Dierkes N., Westner I.M., and Kretzschmar H.A. Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology. J. Virol. 78 (2004) 11051-11060
-
(2004)
J. Virol.
, vol.78
, pp. 11051-11060
-
-
Xiang, W.1
Windl, O.2
Wunsch, G.3
Dugas, M.4
Kohlmann, A.5
Dierkes, N.6
Westner, I.M.7
Kretzschmar, H.A.8
-
63
-
-
34250030069
-
Transcriptome analysis reveals altered cholesterol metabolism during the neurodegeneration in mouse scrapie model
-
Xiang W., Hummel M., Mitteregger G., Pace C., Windl O., Mansmann U., and Kretzschmar H.A. Transcriptome analysis reveals altered cholesterol metabolism during the neurodegeneration in mouse scrapie model. J. Neurochem. 102 (2007) 834-847
-
(2007)
J. Neurochem.
, vol.102
, pp. 834-847
-
-
Xiang, W.1
Hummel, M.2
Mitteregger, G.3
Pace, C.4
Windl, O.5
Mansmann, U.6
Kretzschmar, H.A.7
-
64
-
-
33646126055
-
Regulation of PrPC expression: nerve growth factor (NGF) activates the prion gene promoter through the MEK1 pathway in PC12 cells
-
Zawlik I., Witusik M., Hulas-Bigoszewska K., Piaskowski S., Szybka M., Golanska E., Liberski P.P., and Rieske P. Regulation of PrPC expression: nerve growth factor (NGF) activates the prion gene promoter through the MEK1 pathway in PC12 cells. Neurosci. Lett. 400 (2006) 58-62
-
(2006)
Neurosci. Lett.
, vol.400
, pp. 58-62
-
-
Zawlik, I.1
Witusik, M.2
Hulas-Bigoszewska, K.3
Piaskowski, S.4
Szybka, M.5
Golanska, E.6
Liberski, P.P.7
Rieske, P.8
|