In vitro toxicity of cereulide on porcine pancreatic Langerhans islets

Toxicon

Volumn 51, Issue 6, 2008, Pages 1029-1037

  Virtanen, Suvi M ^a,b   Roivainen, Merja ^b   Andersson, Maria A ^c   Ylipaasto, Petri ^b   Hoornstra, Douwe ^c   Mikkola, Raimo ^c   Salkinoja Salonen, Mirja S ^c  

^a UNIVERSITY OF TAMPERE   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Bacillus cereus; Beta cell; Cereulide; Cytotoxicity; Food poisoning; Ionophore; Porcine pancreas; Potassium carrier; Potato

Indexed keywords

BAFILOMYCIN A1; CEREULIDE; INSULIN; VALINOMYCIN;

ANIMAL CELL; ARTICLE; BACTERIUM; CELL DEATH; CONTROLLED STUDY; FETUS; IN VITRO STUDY; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PURIFICATION;

ANIMALS; BACILLUS CEREUS; BACTERIAL TOXINS; CELL DEATH; CELL SURVIVAL; DEPSIPEPTIDES; DIARRHEA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOOD POISONING; INSULIN; ISLETS OF LANGERHANS; PANCREAS; SWINE; TIME FACTORS; TOXICITY TESTS;

BACILLUS CEREUS; BACTERIA (MICROORGANISMS); MAMMALIA; SOLANUM TUBEROSUM; SUS;

EID: 43049121304     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.01.019     Document Type: Article

References (36)

1. Agata N., Mori M., Ohta M., Suwan S., Ohtani I., and Isobe M. A novel dodecadepsipeptide, cereulide, isolated from Bacillus cereus causes vacuole formation in HEp-2 cells. FEMS Microbiol. Lett. 121 (1994) 31-34
2. Agata N., Ohta M., and Yokoayma K. Production of Bacillus cereus emetic toxin (cereulide) in various foods. Int. J. Food Microbiol. 73 (2002) 23-27
3. Altayar M., and Sutherland A.D. Bacillus cereus is common in the environment but emetic toxin producing isolates are rare. J. Appl. Microbiol. 100 (2006) 7-14
4. Andersson M.A., Mikkola R., Helin J., Andersson M.C., and Salkinoja-Salonen M. A novel sensitive bioassay for the detection of Bacillus cereus emetic toxin and related depsipeptide ionophores. Appl. Environ. Microbiol. 64 (1998) 1338-1342
5. Andersson M.A., Jääskeläinen E.J., Shaheen R., Pirhonen T., Wijnands L.M., and Salkinoja-Salonen M.S. Sperm bioassay for rapid detection of cereulide producing Bacillus cereus in food and related environments. Int. J. Food Microbiol. 94 2 (2004) 175-183
6. Andersson M.A., Hakulinen P., Honkalampi-Hämäläinen U., Hoornstra D., Lhuguenot J.-C., Mäki-Paakkanen J., Savolainen M., Severin I., Stammati A., Turco L., Weber a., von Wright A., Zucco F., and Salkinoja-Salonen M.S. Toxicological profile of cereulide, the Bacillus cereus emetic toxin, in functional assays with different mammalian and bacterial cells. Toxicon 49 (2007) 351-367
7. Apetroaie C., Andersson M.A., Spröer C., Tsitko I., Shaheen R., Jääskeläinen E.L., Wijnands L.M., Heikkilä R., and Salkinoja-Salonen M.S. Cereulide producing strains of Bacillus cereus show diversity. Arch. Microbiol. 184 (2005) 141-151 IMP2.374
8. Ash C., Farrow J.A., Dorsch M., Stackebrandt E., and Collins M.D. Comparative analysis of Bacillus anthracis, Bacillus cereus, and related species on the basis of reverse transcriptase sequencing of 16S rRNA. Int. J. Syst. Bacteriol. 41 (1991) 343-346
9. Dierick K., Van Coillie E., Swiecicka I., Meyfroidt G., Devlieger H., Meulemans A., Hoedemakers G., Fourie L., Heyndrickx M., and Mahillon J. A fatal family outbreak of Bacillus cereus food poisoning. J. Clin. Microbiol. 43 8 (2005) 4277-4279
10. Eizirik D.L., Pipeleers D.G., Ling Z., Welsh N., Hellerstrom C., and Andersson A. Proc. Natl. Acad. Sci. USA 91 (1994) 9253-9256
11. Herrington J., Sanchez M., Wunderler D., Yan L., Bugianesi R.M., Dick I.E., Clark S.A., Brochu R.M., Priest B.T., Kohler M.G., et al. J. Physiol. 567 (2005) 159-175
12. Hoornstra D., Andersson M.A., Mikkola R., and Salkinoja-Salonen M.S. A new method for in vitro detection of microbially produced mitochondrial toxins. Toxicol. In Vitro 17 (2003) 745-751
13. Isobe M., Ishikawa T., Suwan S., Agata N., and Ohta M. Synthesis and activity of cereulide, a cyclic dodecadepsipeptide ionophore as emetic toxin from Bacillus cereus. Bioorg. Med. Chem. Lett. 5 (1995) 2855-2858
14. Jääskeläinen E., Häggblom M., Andersson M.A., Vanne L., and Salkinoja-Salonen M. Potential of bakery products for producing cereulide, the Bacillus cereus emetic toxin: quantitative analysis by chemical and biological methods. J. Food Protect. 66 6 (2003) 1047-1054
15. Jääskeläinen E.L., Teplova V., Andersson M.A., Andersson L.C., Tammela P., Andersson M.C., Pirhonen T.I., Saris N.-E., Vuorela P., and Salkinoja-Salonen M.S. In vitro assay for human toxicity of cereulide, the emetic toxin produced by food poisoning Bacillus cereus. Toxicol. In Vitro 17 (2003) 737-744
16. Korbutt G.S., Elliot J.F., AO Z.L., Smith D.K., Warnock G.L., and Rajotte R.V. Large scale isolation, growth, and function of porcine neonatal islet cells. J. Clin. Invest. 97 (1996) 2119-2129
17. Koster J.C., Permutt M.A., and Nichols C.G. Diabetes 54 (2005) 3065-3072
18. Maechler P., Carobbio S., and Rubi B. In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion. Int. J. Biochem. Cell Biol. 38 (2006) 696-709
19. Mahler H., Pasi A., Kramer J., Schulte P., Scoging A., Baer W., and Kraehenbuehl S. Fulminant liver failure in association with the emetic toxin of Bacillus cereus. New Engl. J. Med. 336 (1997) 1143-1148
20. Mikami Y., Takeda K., Murakami T., and Matsuno S. Vascular anatomy of the pancreas. In: Pour P.M. (Ed). Toxicology of the Pancreas (2006), Taylor & Francis Publishers, Boca, Raton, London, New York, Singapore 75-89
21. Mikkola R., Saris N.E., Grigoriev P.A., Andersson M.A., and Salkinoja-Salonen M.S. Ionophoretic properties and mitochondrial effects of cereulide: the emetic toxin of B. cereus. Eur. J. Biochem. 263 (1999) 112-117
22. Myers M.A., Mackay I.R., Rowley M.J., and Zimmet P.Z. Dietary microbial toxins and type 1 diabetes-a new meaning for seed and soil. Diabetologia 44 (2001) 1199-1200
23. Paananen A., Mikkola R., Sareneva T., Matikainen S., Hess M., Andersson M., Julkunen I., Salkinoja-Salonen M.S., and Timonen T. Inhibition of human natural killer cell activity by cereulide, an emetic toxin from Bacillus cereus. Clin. Exp. Immunol. 129 (2002) 420-428
24. Pirttijärvi T.S., Andersson M.A., Scoging A., and Salkinoja-Salonen M.S. Evaluation of methods for recognizing strains of Bacillus cereus with food poisoning potential among industrial contaminants. Syst. Appl. Microbiol. 22 (1999) 133-144
25. Roivainen M., Ylipaasto P., Ustinov J.T., Hovi T., and Otonkoski T. Fetal porcine beta-cells as a substitute for primary human beta cells in screening of enteroviruses for beta cell tropism. J. Gen. Virol. 82 (2001) 1909-1916
26. Scifinder, Version 2006. Chemical Abstracts Service, Columbus, Ohio. Log P value for CAS RN 88899-55-2, calculated using ACD/Labs software version 8.14. ACD/Labs 1994-2007.
27. Shaheen R., Andersson M.A., Apetroaie C., Schulz A., Ehling-Schulz M., Ollilainen V.-M., and Salkinoja-Salonen M.S. Int. J. Food Microbiol. 107 (2006) 287-294
28. Shinagawa K., Konuma H., Sekita H., and Sugii S. Emesis of rhesus monkeys induced by intragastric administration with the HEp-2 vacuolation factor, cereulide, produced by Bacillus cereus. FEMS Microbiol. Lett. 130 (1995) 87-90
29. Svensson B., Monthán A., Shaheen R., Andersson M.A., Salkinoja-Salonen M., and Christiansson A. Int. Dairy J. 16 (2006) 740-749
30. Takabe F., and Oya M. An autopsy case of food poisoning associated with Bacillus cereus. Forens. Sci. 7 (1976) 97-101
31. Teplova V., Jääskeläinen E., Salkinoja-Salonen M.S., Saris N.-E., Serlachius M., Li F.-Y., and Andersson L. Differentiated Paju cells have increased resistance to toxic effects of potassium ionophores. Acta Biochem. Pol. 51 2 (2004) 539-544
32. Teplova V.V., Mikkola R., Tonshin A.A., Saris N.-E.L., and Salkinoja-Salonen M.S. The higher toxicity of cereulide relative to valinomycin is due to its higher affinity for potassium at physiological plasma concentration. Toxicol. Appl. Pharmacol. 210 (2006) 39-46
33. Teplova V.V., Tonshin A.A., Grigoriev P.A., Saris N.-E.L., and Salkinoja-Salonen M.S. Bafilomycin A1 is a potassium ionophore that impairs mitochondrial functions. J. Bioenerg. Biomembr. 39 (2007) 321-329
34. Turnbull P.C.B., Kramer J., Jǿrgensen K., Gilbert R.J., and Melling J. Properties and production characteristics of vomiting, diarrheal and necrotic toxins of Bacillus cereus. Am. J. Clin. Nutr. 32 (1979) 219-228
35. Wang G.Y.S., Kuramoto M., Yamada K., Yazawa K., and Uemura D. Homocereulide, an extremely potent cytotoxic depsipeptide from the marine bacterium Bacillus cereus. Chem. Lett. 24 (1995) 791-792
36. Wijnands L.M., Dufrenne J.B., Rombouts F.M., In't Veld P.H., and Van Leusden F.M. Prevalence of potentially pathogenic Bacillus cereus in food commodities in the Netherlands. J. Food Protect. 69 (2006) 2587-2594