A valine to phenylalanine mutation in the precore region of hepatitis B virus causes intracellular retention and impaired secretion of HBe-antigen

Hepatology Research

Volumn 38, Issue 6, 2008, Pages 580-592

  Chen, Chien Yu ^a   Crowther, Carol ^b   Kew, Michael C ^a   Kramvis, Anna ^a,b  

^a Department of Medicine

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Aggresomes; HBe antigen; Mutant; Signalpeptide cleavage

Indexed keywords

ALPHA TUBULIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CORE PROTEIN; CYTOKERATIN; GAMMA TUBULIN; HEAT SHOCK PROTEIN; HEPATITIS B(E) ANTIGEN; PHENYLALANINE; PROTEASOME; PROTEASOME INHIBITOR; UBIQUITIN; VALINE; VIMENTIN; VIRUS DNA;

AGGRESOME; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL CULTURE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; DNA HYBRIDIZATION; ENDOPLASMIC RETICULUM; GENE MUTATION; GENETIC TRANSFECTION; GENOTYPE; GOLGI COMPLEX; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; INTERMEDIATE FILAMENT; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ISOLATION; REAL TIME POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; VIRUS PARTICLE; VIRUS REPLICATION; WILD TYPE;

EID: 43049118617     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2007.00315.x     Document Type: Article

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