메뉴 건너뛰기




Volumn 5, Issue 2, 2008, Pages 104-115

The role of calcium and the L-type calcium channel in pathological remodeling of the heart

Author keywords

Calcium; Hypertrophy; L type Ca2+ channel; Remodeling; Signaling

Indexed keywords

CALCINEURIN; CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN KINASE C; PROTEIN KINASE D; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NFAT;

EID: 43049087391     PISSN: 15672700     EISSN: None     Source Type: Journal    
DOI: 10.2174/156727008784223909     Document Type: Review
Times cited : (3)

References (108)
  • 1
    • 34848894264 scopus 로고    scopus 로고
    • What cardiologists should know about calcium ion channels and their regulation by reactive oxygen species
    • Hool LC. What cardiologists should know about calcium ion channels and their regulation by reactive oxygen species. Heart Lung Circ 2007; 16: 361-72.
    • (2007) Heart Lung Circ , vol.16 , pp. 361-372
    • Hool, L.C.1
  • 2
    • 33847232634 scopus 로고    scopus 로고
    • Redox control of calcium channels: From mechanisms to therapeutic opportunities
    • Hool LC, Corry B. Redox control of calcium channels: from mechanisms to therapeutic opportunities. Antioxid Redox Signal 2007; 9: 409-35.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 409-435
    • Hool, L.C.1    Corry, B.2
  • 4
    • 0023161154 scopus 로고    scopus 로고
    • Cooper G, 4th. Cardiocyte adaptation to chronically altered load. Annu Rev Physiol 1987; 49: 501-18.
    • Cooper G, 4th. Cardiocyte adaptation to chronically altered load. Annu Rev Physiol 1987; 49: 501-18.
  • 5
    • 0029146141 scopus 로고
    • Biological adaptation of the myocardium to chronic mechanical overload. Molecular determinants of the autonomic nervous system
    • Mondry A, Swynghedauw B. Biological adaptation of the myocardium to chronic mechanical overload. Molecular determinants of the autonomic nervous system. Eur Heart J 1995; 16 (Suppl I): 64-73.
    • (1995) Eur Heart J , vol.16 , Issue.SUPPL. I , pp. 64-73
    • Mondry, A.1    Swynghedauw, B.2
  • 6
    • 0002537440 scopus 로고    scopus 로고
    • Cardiac hypertrophy: The good, the bad, and the ugly
    • Frey N, Olson EN. Cardiac hypertrophy: the good, the bad, and the ugly. Annu Rev Physiol 2003; 65: 45-79.
    • (2003) Annu Rev Physiol , vol.65 , pp. 45-79
    • Frey, N.1    Olson, E.N.2
  • 7
    • 0037095815 scopus 로고    scopus 로고
    • Calcineurin and cardiac hypertrophy: Where have we been? Where are we going?
    • Wilkins BJ, Molkentin JD. Calcineurin and cardiac hypertrophy: where have we been? Where are we going? J Physiol 2002; 541: 1-8.
    • (2002) J Physiol , vol.541 , pp. 1-8
    • Wilkins, B.J.1    Molkentin, J.D.2
  • 8
    • 33751032385 scopus 로고    scopus 로고
    • Calcium microdomains: Organization and function
    • Berridge MJ. Calcium microdomains: organization and function. Cell Calcium 2006; 40: 405-12.
    • (2006) Cell Calcium , vol.40 , pp. 405-412
    • Berridge, M.J.1
  • 10
    • 20344401818 scopus 로고    scopus 로고
    • Mechanisms and models in heart failure: The biomechanical model and beyond
    • Mann DL, Bristow MR. Mechanisms and models in heart failure: the biomechanical model and beyond. Circulation 2005; 111: 2837-49.
    • (2005) Circulation , vol.111 , pp. 2837-2849
    • Mann, D.L.1    Bristow, M.R.2
  • 11
    • 33645971014 scopus 로고    scopus 로고
    • Remodelling Ca2+ signalling systems and cardiac hypertrophy
    • Berridge MJ. Remodelling Ca2+ signalling systems and cardiac hypertrophy. Biochem Soc Trans 2006; 34: 228-31.
    • (2006) Biochem Soc Trans , vol.34 , pp. 228-231
    • Berridge, M.J.1
  • 12
    • 0029816659 scopus 로고    scopus 로고
    • Cellular functions of immunophilins
    • Marks AR. Cellular functions of immunophilins. Physiol Rev 1996; 76: 631-49.
    • (1996) Physiol Rev , vol.76 , pp. 631-649
    • Marks, A.R.1
  • 13
    • 0026738916 scopus 로고
    • FK506 binding protein associated with the calcium release channel (ryanodine receptor)
    • Jayaraman T, Brillantes AM, Timerman AP, et al. FK506 binding protein associated with the calcium release channel (ryanodine receptor). J Biol Chem 1992; 267: 9474-7.
    • (1992) J Biol Chem , vol.267 , pp. 9474-9477
    • Jayaraman, T.1    Brillantes, A.M.2    Timerman, A.P.3
  • 14
    • 0029810883 scopus 로고    scopus 로고
    • Selective binding of FKBP12.6 by the cardiac ryanodine receptor
    • Timerman AP, Onoue H, Xin HB, et al. Selective binding of FKBP12.6 by the cardiac ryanodine receptor. J Biol Chem 1996; 271: 20385-91.
    • (1996) J Biol Chem , vol.271 , pp. 20385-20391
    • Timerman, A.P.1    Onoue, H.2    Xin, H.B.3
  • 15
    • 0037149508 scopus 로고    scopus 로고
    • Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy
    • Xin HB, Senbonmatsu T, Cheng DS, et al. Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. Nature 2002; 416: 334-8.
    • (2002) Nature , vol.416 , pp. 334-338
    • Xin, H.B.1    Senbonmatsu, T.2    Cheng, D.S.3
  • 16
    • 0035830828 scopus 로고    scopus 로고
    • Cardiac hypertrophy and impaired relaxation in transgenic mice overexpressing triadin 1
    • Kirchhefer U, Neumann J, Baba HA, et al. Cardiac hypertrophy and impaired relaxation in transgenic mice overexpressing triadin 1. J Biol Chem 2001; 276: 4142-9.
    • (2001) J Biol Chem , vol.276 , pp. 4142-4149
    • Kirchhefer, U.1    Neumann, J.2    Baba, H.A.3
  • 17
    • 0001229903 scopus 로고    scopus 로고
    • Alterations in calcium handling in cardiac hypertrophy and heart failure
    • Balke CW, Shorofsky SR. Alterations in calcium handling in cardiac hypertrophy and heart failure. Cardiovasc Res 1998; 37: 290-9.
    • (1998) Cardiovasc Res , vol.37 , pp. 290-299
    • Balke, C.W.1    Shorofsky, S.R.2
  • 18
    • 4444382387 scopus 로고    scopus 로고
    • Calcium-calcineurin signaling in the regulation of cardiac hypertrophy
    • Wilkins BJ, Molkentin JD. Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem Biophys Res Commun 2004; 322: 1178-91.
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 1178-1191
    • Wilkins, B.J.1    Molkentin, J.D.2
  • 19
    • 3242784087 scopus 로고    scopus 로고
    • Myocyte hypertrophy and apoptosis: A balancing act
    • van Empel VP, De Windt LJ. Myocyte hypertrophy and apoptosis: a balancing act. Cardiovasc Res 2004; 63: 487-99.
    • (2004) Cardiovasc Res , vol.63 , pp. 487-499
    • van Empel, V.P.1    De Windt, L.J.2
  • 20
    • 0034123657 scopus 로고    scopus 로고
    • Mechanical stress-induced cardiac hypertrophy: Mechanisms and signal transduction pathways
    • Ruwhof C, van der Laarse A. Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways. Cardiovasc Res 2000; 47: 23-37.
    • (2000) Cardiovasc Res , vol.47 , pp. 23-37
    • Ruwhof, C.1    van der Laarse, A.2
  • 21
    • 14644414790 scopus 로고    scopus 로고
    • Protein kinase cascades in the regulation of cardiac hypertrophy
    • Dorn GW 2nd, Force T. Protein kinase cascades in the regulation of cardiac hypertrophy. J Clin Invest 2005; 115: 527-37.
    • (2005) J Clin Invest , vol.115 , pp. 527-537
    • Dorn 2nd, G.W.1    Force, T.2
  • 22
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function, and regulation
    • Newton AC. Protein kinase C: structure, function, and regulation. J Biol Chem 1995; 270: 28495-8.
    • (1995) J Biol Chem , vol.270 , pp. 28495-28498
    • Newton, A.C.1
  • 23
    • 0032802635 scopus 로고    scopus 로고
    • Alterations in protein kinase A and protein kinase C levels in heart failure due to genetic cardiomyopathy
    • Wang J, Liu X, Arneja AS, Dhalla NS. Alterations in protein kinase A and protein kinase C levels in heart failure due to genetic cardiomyopathy. Can J Cardiol 1999; 15: 683-90.
    • (1999) Can J Cardiol , vol.15 , pp. 683-690
    • Wang, J.1    Liu, X.2    Arneja, A.S.3    Dhalla, N.S.4
  • 24
    • 33846889551 scopus 로고    scopus 로고
    • Derepression of pathological cardiac genes by members of the CaM kinase superfamily
    • McKinsey TA. Derepression of pathological cardiac genes by members of the CaM kinase superfamily. Cardiovasc Res 2007; 73: 667-77.
    • (2007) Cardiovasc Res , vol.73 , pp. 667-677
    • McKinsey, T.A.1
  • 27
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • Molkentin JD, Lu JR, Antos CL, et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 1998; 93: 215-28.
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1    Lu, J.R.2    Antos, C.L.3
  • 28
    • 0033981108 scopus 로고    scopus 로고
    • Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy
    • Taigen T, De Windt LJ, Lim HW, Molkentin JD. Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci USA 2000; 97: 1196-201.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1196-1201
    • Taigen, T.1    De Windt, L.J.2    Lim, H.W.3    Molkentin, J.D.4
  • 29
    • 0036837672 scopus 로고    scopus 로고
    • Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth
    • Wilkins BJ, De Windt LJ, Bueno OF, et al. Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth. Mol Cell Biol 2002; 22: 7603-13.
    • (2002) Mol Cell Biol , vol.22 , pp. 7603-7613
    • Wilkins, B.J.1    De Windt, L.J.2    Bueno, O.F.3
  • 30
    • 33744926666 scopus 로고    scopus 로고
    • PKD at the crossroads of DAG and PKC signaling
    • Wang QJ. PKD at the crossroads of DAG and PKC signaling. Trends Pharmacol Sci 2006; 27: 317-23.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 317-323
    • Wang, Q.J.1
  • 31
    • 0030875166 scopus 로고    scopus 로고
    • Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy
    • Wakasaki H, Koya D, Schoen FJ, et al. Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy. Proc Natl Acad Sci U S A 1997; 94: 9320-5.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9320-9325
    • Wakasaki, H.1    Koya, D.2    Schoen, F.J.3
  • 32
    • 0030696157 scopus 로고    scopus 로고
    • Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates
    • Bowman JC, Steinberg SF, Jiang T, Geenen DL, Fishman GI, Buttrick PM. Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates. J Clin Invest 1997; 100: 2189-95.
    • (1997) J Clin Invest , vol.100 , pp. 2189-2195
    • Bowman, J.C.1    Steinberg, S.F.2    Jiang, T.3    Geenen, D.L.4    Fishman, G.I.5    Buttrick, P.M.6
  • 34
    • 33745166297 scopus 로고    scopus 로고
    • Expression of protein kinase C isoforms in cardiac hypertrophy and heart failure due to volume overload
    • Sentex E, Wang X, Liu X, Lukas A, Dhalla NS. Expression of protein kinase C isoforms in cardiac hypertrophy and heart failure due to volume overload. Can J Physiol Pharmacol 2006; 84: 227-38.
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 227-238
    • Sentex, E.1    Wang, X.2    Liu, X.3    Lukas, A.4    Dhalla, N.S.5
  • 35
    • 33646161306 scopus 로고    scopus 로고
    • Regulation of cardiac stress signaling by protein kinase d1
    • Harrison BC, Kim MS, van Rooij E, et al. Regulation of cardiac stress signaling by protein kinase d1. Mol Cell Biol 2006; 26: 3875-88.
    • (2006) Mol Cell Biol , vol.26 , pp. 3875-3888
    • Harrison, B.C.1    Kim, M.S.2    van Rooij, E.3
  • 36
    • 0030660245 scopus 로고    scopus 로고
    • Mechanism of action of beta-blocking agents in heart failure
    • Bristow MR. Mechanism of action of beta-blocking agents in heart failure. Am J Cardiol 1997; 80: 26L-40L.
    • (1997) Am J Cardiol , vol.80
    • Bristow, M.R.1
  • 38
    • 0037007679 scopus 로고    scopus 로고
    • Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents
    • Lowes BD, Gilbert EM, Abraham WT, et al. Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents. N Engl J Med 2002; 346: 1357-65.
    • (2002) N Engl J Med , vol.346 , pp. 1357-1365
    • Lowes, B.D.1    Gilbert, E.M.2    Abraham, W.T.3
  • 39
    • 0029149020 scopus 로고
    • Isoproterenol infusion induces alterations in expression of hypertrophy-associated genes in rat heart
    • Boluyt MO, Long X, Eschenhagen T, et al. Isoproterenol infusion induces alterations in expression of hypertrophy-associated genes in rat heart. Am J Physiol 1995; 269: H638-47.
    • (1995) Am J Physiol , vol.269
    • Boluyt, M.O.1    Long, X.2    Eschenhagen, T.3
  • 40
    • 0035853110 scopus 로고    scopus 로고
    • Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo
    • Rothermel BA, McKinsey TA, Vega RB, et al. Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A 2001; 98: 3328-33.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 3328-3333
    • Rothermel, B.A.1    McKinsey, T.A.2    Vega, R.B.3
  • 42
    • 20244362095 scopus 로고    scopus 로고
    • Calmodulin kinase II inhibition protects against structural heart disease
    • Zhang R, Khoo MS, Wu Y, et al. Calmodulin kinase II inhibition protects against structural heart disease. Nat Med 2005; 11: 409-17.
    • (2005) Nat Med , vol.11 , pp. 409-417
    • Zhang, R.1    Khoo, M.S.2    Wu, Y.3
  • 43
    • 0027234582 scopus 로고
    • Targeted developmental overexpression of calmodulin induces proliferative and hypertrophic growth of cardiomyocytes in transgenic mice
    • Gruver CL, DeMayo F, Goldstein MA, Means AR. Targeted developmental overexpression of calmodulin induces proliferative and hypertrophic growth of cardiomyocytes in transgenic mice. Endocrinology 1993; 133: 376-88.
    • (1993) Endocrinology , vol.133 , pp. 376-388
    • Gruver, C.L.1    DeMayo, F.2    Goldstein, M.A.3    Means, A.R.4
  • 44
    • 0030609163 scopus 로고    scopus 로고
    • The nuclear deltaB isoform of Ca2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes
    • Ramirez MT, Zhao XL, Schulman H, Brown JH. The nuclear deltaB isoform of Ca2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes. J Biol Chem 1997; 272: 31203-8.
    • (1997) J Biol Chem , vol.272 , pp. 31203-31208
    • Ramirez, M.T.1    Zhao, X.L.2    Schulman, H.3    Brown, J.H.4
  • 45
    • 0034463866 scopus 로고    scopus 로고
    • Chronic elevation of calmodulin in the ventricles of transgenic mice increases the autonomous activity of calmodulin-dependent protein kinase II, which regulates atrial natriuretic factor gene expression
    • Colomer JM, Means AR. Chronic elevation of calmodulin in the ventricles of transgenic mice increases the autonomous activity of calmodulin-dependent protein kinase II, which regulates atrial natriuretic factor gene expression. Mol Endocrinol 2000; 14: 1125-36.
    • (2000) Mol Endocrinol , vol.14 , pp. 1125-1136
    • Colomer, J.M.1    Means, A.R.2
  • 46
    • 12344257736 scopus 로고    scopus 로고
    • PKCepsilon-PKD1 signaling complex at Z-discs plays a pivotal role in the cardiac hypertrophy induced by G-protein coupling receptor agonists
    • Iwata M, Maturana A, Hoshijima M, et al. PKCepsilon-PKD1 signaling complex at Z-discs plays a pivotal role in the cardiac hypertrophy induced by G-protein coupling receptor agonists. Biochem Biophys Res Commun 2005; 327: 1105-13.
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 1105-1113
    • Iwata, M.1    Maturana, A.2    Hoshijima, M.3
  • 47
    • 0029964752 scopus 로고    scopus 로고
    • Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway
    • Zugaza JL, Sinnett-Smith J, Van Lint J, Rozengurt E. Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway. EMBO J 1996; 15: 6220-30.
    • (1996) EMBO J , vol.15 , pp. 6220-6230
    • Zugaza, J.L.1    Sinnett-Smith, J.2    Van Lint, J.3    Rozengurt, E.4
  • 48
    • 4544315655 scopus 로고    scopus 로고
    • Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5
    • Vega RB, Harrison BC, Meadows E, et al. Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol Cell Biol 2004; 24: 8374-85.
    • (2004) Mol Cell Biol , vol.24 , pp. 8374-8385
    • Vega, R.B.1    Harrison, B.C.2    Meadows, E.3
  • 49
    • 0027298699 scopus 로고
    • Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes
    • Yamazaki T, Tobe K, Hoh E, et al. Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes. J Biol Chem 1993; 268: 12069-76.
    • (1993) J Biol Chem , vol.268 , pp. 12069-12076
    • Yamazaki, T.1    Tobe, K.2    Hoh, E.3
  • 50
    • 0031239115 scopus 로고    scopus 로고
    • Protein kinase A and protein kinase C synergistically activate the Raf-1 kinase/mitogen-activated protein kinase cascade in neonatal rat cardiomyocytes
    • Yamazaki T, Komuro I, Zou Y, et al. Protein kinase A and protein kinase C synergistically activate the Raf-1 kinase/mitogen-activated protein kinase cascade in neonatal rat cardiomyocytes. J Mol Cell Cardiol 1997; 29: 2491-501.
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 2491-2501
    • Yamazaki, T.1    Komuro, I.2    Zou, Y.3
  • 51
    • 0034383952 scopus 로고    scopus 로고
    • The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice
    • Bueno OF, De Windt LJ, Tymitz KM, et al. The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO J 2000; 19: 6341-50.
    • (2000) EMBO J , vol.19 , pp. 6341-6350
    • Bueno, O.F.1    De Windt, L.J.2    Tymitz, K.M.3
  • 52
    • 0035355360 scopus 로고    scopus 로고
    • Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy
    • Nicol RL, Frey N, Pearson G, Cobb M, Richardson J, Olson EN. Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy. EMBO J 2001; 20: 2757-67.
    • (2001) EMBO J , vol.20 , pp. 2757-2767
    • Nicol, R.L.1    Frey, N.2    Pearson, G.3    Cobb, M.4    Richardson, J.5    Olson, E.N.6
  • 53
    • 0031939753 scopus 로고    scopus 로고
    • Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
    • Wang Y, Huang S, Sah VP, et al. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem 1998; 273: 2161-8.
    • (1998) J Biol Chem , vol.273 , pp. 2161-2168
    • Wang, Y.1    Huang, S.2    Sah, V.P.3
  • 54
    • 0034105968 scopus 로고    scopus 로고
    • TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice
    • Zhang D, Gaussin V, Taffet GE, et al. TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. Nat Med 2000; 6: 556-63.
    • (2000) Nat Med , vol.6 , pp. 556-563
    • Zhang, D.1    Gaussin, V.2    Taffet, G.E.3
  • 55
    • 33745202365 scopus 로고    scopus 로고
    • NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure
    • Murdoch CE, Zhang M, Cave AC, Shah AM. NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure. Cardiovasc Res 2006; 71: 208-15.
    • (2006) Cardiovasc Res , vol.71 , pp. 208-215
    • Murdoch, C.E.1    Zhang, M.2    Cave, A.C.3    Shah, A.M.4
  • 57
    • 14644442283 scopus 로고    scopus 로고
    • Oxygen, oxidative stress, hypoxia, and heart failure
    • Giordano FJ. Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest 2005; 115: 500-8.
    • (2005) J Clin Invest , vol.115 , pp. 500-508
    • Giordano, F.J.1
  • 59
    • 34247146483 scopus 로고    scopus 로고
    • Transient exposure to hydrogen peroxide causes an increase in mitochondria-derived superoxide as a result of sustained alteration in L-type Ca2+ channel function in the absence of apoptosis in ventricular myocytes
    • Viola HM, Arthur PG, Hool LC. Transient exposure to hydrogen peroxide causes an increase in mitochondria-derived superoxide as a result of sustained alteration in L-type Ca2+ channel function in the absence of apoptosis in ventricular myocytes. Circ Res 2007; 100: 1036-44.
    • (2007) Circ Res , vol.100 , pp. 1036-1044
    • Viola, H.M.1    Arthur, P.G.2    Hool, L.C.3
  • 60
    • 22744441098 scopus 로고    scopus 로고
    • Role of NAD(P)H oxidase in the regulation of cardiac L-type Ca2+ channel function during acute hypoxia
    • Hool LC, Di Maria CA, Viola HM, Arthur PG. Role of NAD(P)H oxidase in the regulation of cardiac L-type Ca2+ channel function during acute hypoxia. Cardiovasc Res 2005; 67: 624-35.
    • (2005) Cardiovasc Res , vol.67 , pp. 624-635
    • Hool, L.C.1    Di Maria, C.A.2    Viola, H.M.3    Arthur, P.G.4
  • 61
    • 0345258510 scopus 로고    scopus 로고
    • Regulation of hypertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes
    • Sabri A, Hughie HH, Lucchesi PA. Regulation of hypertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes. Antioxid Redox Signal 2003; 5: 731-40.
    • (2003) Antioxid Redox Signal , vol.5 , pp. 731-740
    • Sabri, A.1    Hughie, H.H.2    Lucchesi, P.A.3
  • 62
    • 0031849502 scopus 로고    scopus 로고
    • Causative role of oxyradicals in myocardial stunning: A proven hypothesis. A brief review of the evidence demonstrating a major role of reactive oxygen species in several forms of postischemic dysfunction
    • Bolli R. Causative role of oxyradicals in myocardial stunning: a proven hypothesis. A brief review of the evidence demonstrating a major role of reactive oxygen species in several forms of postischemic dysfunction. Basic Res Cardiol 1998; 93: 156-62.
    • (1998) Basic Res Cardiol , vol.93 , pp. 156-162
    • Bolli, R.1
  • 63
    • 3042856265 scopus 로고    scopus 로고
    • Role of oxidative stress in cardiac remodelling after myocardial infarction
    • Grieve DJ, Byrne JA, Cave AC, Shah AM. Role of oxidative stress in cardiac remodelling after myocardial infarction. Heart Lung Circ 2004; 13: 132-8.
    • (2004) Heart Lung Circ , vol.13 , pp. 132-138
    • Grieve, D.J.1    Byrne, J.A.2    Cave, A.C.3    Shah, A.M.4
  • 64
    • 33645086130 scopus 로고    scopus 로고
    • Reactive oxygen species in cardiac signalling: From mitochondria to plasma membrane ion channels
    • Hool LC. Reactive oxygen species in cardiac signalling: from mitochondria to plasma membrane ion channels. Clin Exp Pharmacol Physiol 2006; 33: 146-51.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 146-151
    • Hool, L.C.1
  • 65
    • 0034596947 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS)-induced ROS release: A new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes
    • Zorov DB, Filburn CR, Klotz LO, Zweier JL, Sollott SJ. Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med 2000; 192: 1001-14.
    • (2000) J Exp Med , vol.192 , pp. 1001-1014
    • Zorov, D.B.1    Filburn, C.R.2    Klotz, L.O.3    Zweier, J.L.4    Sollott, S.J.5
  • 66
    • 0029998621 scopus 로고    scopus 로고
    • The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal
    • Bernardi P, Petronilli V. The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal. J Bioenerg Biomembr 1996; 28: 131-8.
    • (1996) J Bioenerg Biomembr , vol.28 , pp. 131-138
    • Bernardi, P.1    Petronilli, V.2
  • 67
    • 0032504717 scopus 로고    scopus 로고
    • From calcium signaling to cell death: Two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state
    • Ichas F, Mazat JP. From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state. Biochim Biophys Acta 1998; 1366: 33-50.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 33-50
    • Ichas, F.1    Mazat, J.P.2
  • 68
    • 0242582202 scopus 로고    scopus 로고
    • Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes
    • Aon MA, Cortassa S, Marban E, O'Rourke B. Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes. J Biol Chem 2003; 278: 44735-44.
    • (2003) J Biol Chem , vol.278 , pp. 44735-44744
    • Aon, M.A.1    Cortassa, S.2    Marban, E.3    O'Rourke, B.4
  • 69
    • 0034674055 scopus 로고    scopus 로고
    • Estimation of H2O2 gradients across biomembranes
    • Antunes F, Cadenas E. Estimation of H2O2 gradients across biomembranes. FEBS Lett 2000; 475: 121-6.
    • (2000) FEBS Lett , vol.475 , pp. 121-126
    • Antunes, F.1    Cadenas, E.2
  • 70
    • 0034623786 scopus 로고    scopus 로고
    • Hypoxia increases the sensitivity of the L-type Ca(2+) current to beta-adrenergic receptor stimulation via a C2 region-containing protein kinase C isoform
    • Hool LC. Hypoxia increases the sensitivity of the L-type Ca(2+) current to beta-adrenergic receptor stimulation via a C2 region-containing protein kinase C isoform. Circ Res 2000; 87: 1164-71.
    • (2000) Circ Res , vol.87 , pp. 1164-1171
    • Hool, L.C.1
  • 71
    • 0037019963 scopus 로고    scopus 로고
    • Decreasing cellular hydrogen peroxide with catalase mimics the effects of hypoxia on the sensitivity of the Ltype Ca2+ channel to beta-adrenergic receptor stimulation in cardiac myocytes
    • Hool LC, Arthur PG. Decreasing cellular hydrogen peroxide with catalase mimics the effects of hypoxia on the sensitivity of the Ltype Ca2+ channel to beta-adrenergic receptor stimulation in cardiac myocytes. Circ Res 2002; 91: 601-9.
    • (2002) Circ Res , vol.91 , pp. 601-609
    • Hool, L.C.1    Arthur, P.G.2
  • 72
    • 0037732865 scopus 로고    scopus 로고
    • Electrical remodeling in hearts from a calcium-dependent mouse model of hypertrophy and failure: Complex nature of K+ current changes and action potential duration
    • Bodi I, Muth JN, Hahn HS, et al. Electrical remodeling in hearts from a calcium-dependent mouse model of hypertrophy and failure: complex nature of K+ current changes and action potential duration. J Am Coll Cardiol 2003; 41: 1611-22.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1611-1622
    • Bodi, I.1    Muth, J.N.2    Hahn, H.S.3
  • 73
    • 34249105572 scopus 로고    scopus 로고
    • Mechanisms of Ca2+-dependent calcineurin activation in mechanical stretch-induced hypertrophy
    • Zobel C, Rana OR, Saygili E, et al. Mechanisms of Ca2+-dependent calcineurin activation in mechanical stretch-induced hypertrophy. Cardiology 2007; 107: 281-90.
    • (2007) Cardiology , vol.107 , pp. 281-290
    • Zobel, C.1    Rana, O.R.2    Saygili, E.3
  • 74
    • 0029743817 scopus 로고    scopus 로고
    • Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols
    • Campbell DL, Stamler JS, Strauss HC. Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols. J Gen Physiol 1996; 108: 277-93.
    • (1996) J Gen Physiol , vol.108 , pp. 277-293
    • Campbell, D.L.1    Stamler, J.S.2    Strauss, H.C.3
  • 75
    • 0027194540 scopus 로고
    • A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
    • Lipton SA, Choi YB, Pan ZH, et al. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 1993; 364: 626-32.
    • (1993) Nature , vol.364 , pp. 626-632
    • Lipton, S.A.1    Choi, Y.B.2    Pan, Z.H.3
  • 76
    • 0025118967 scopus 로고
    • Molecular and cellular aspects of thiol-disulfide exchange
    • Gilbert HF. Molecular and cellular aspects of thiol-disulfide exchange. Adv Enzymol Relat Areas Mol Biol 1990; 63: 69-172.
    • (1990) Adv Enzymol Relat Areas Mol Biol , vol.63 , pp. 69-172
    • Gilbert, H.F.1
  • 77
    • 0035947740 scopus 로고    scopus 로고
    • Hypoxia alters the sensitivity of the L-type Ca(2+) channel to alpha-adrenergic receptor stimulation in the presence of beta-adrenergic receptor stimulation
    • Hool LC. Hypoxia alters the sensitivity of the L-type Ca(2+) channel to alpha-adrenergic receptor stimulation in the presence of beta-adrenergic receptor stimulation. Circ Res 2001; 88: 1036-43.
    • (2001) Circ Res , vol.88 , pp. 1036-1043
    • Hool, L.C.1
  • 78
    • 0033082894 scopus 로고    scopus 로고
    • Modulation of recombinant human cardiac L-type Ca2+ channel alpha1C subunits by redox agents and hypoxia
    • Fearon IM, Palmer AC, Balmforth AJ, Ball SG, Varadi G, Peers C. Modulation of recombinant human cardiac L-type Ca2+ channel alpha1C subunits by redox agents and hypoxia. J Physiol 1999; 514 (Pt 3): 629-37.
    • (1999) J Physiol , vol.514 , Issue.PART 3 , pp. 629-637
    • Fearon, I.M.1    Palmer, A.C.2    Balmforth, A.J.3    Ball, S.G.4    Varadi, G.5    Peers, C.6
  • 79
    • 3242752598 scopus 로고    scopus 로고
    • Redox modulation of basal and beta-adrenergically stimulated cardiac L-type Ca(2+) channel activity by phenylarsine oxide
    • Sims C, Harvey RD. Redox modulation of basal and beta-adrenergically stimulated cardiac L-type Ca(2+) channel activity by phenylarsine oxide. Br J Pharmacol 2004; 142: 797-807.
    • (2004) Br J Pharmacol , vol.142 , pp. 797-807
    • Sims, C.1    Harvey, R.D.2
  • 80
    • 1642431690 scopus 로고    scopus 로고
    • Hydrogen peroxide modulates whole cell Ca2+ currents through L-type channels in cultured rat dentate granule cells
    • Akaishi T, Nakazawa K, Sato K, Saito H, Ohno Y, Ito Y. Hydrogen peroxide modulates whole cell Ca2+ currents through L-type channels in cultured rat dentate granule cells. Neurosci Lett 2004; 356: 25-8.
    • (2004) Neurosci Lett , vol.356 , pp. 25-28
    • Akaishi, T.1    Nakazawa, K.2    Sato, K.3    Saito, H.4    Ohno, Y.5    Ito, Y.6
  • 81
    • 0028196994 scopus 로고
    • Myocardial reperfusion injury: Role of oxygen radicals and potential therapy with antioxidants
    • Jeroudi MO, Hartley CJ, Bolli R. Myocardial reperfusion injury: role of oxygen radicals and potential therapy with antioxidants. Am J Cardiol 1994; 73: 2B-7B.
    • (1994) Am J Cardiol , vol.73
    • Jeroudi, M.O.1    Hartley, C.J.2    Bolli, R.3
  • 82
    • 0035186999 scopus 로고    scopus 로고
    • Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy
    • Takemoto M, Node K, Nakagami H, et al. Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy. J Clin Invest 2001; 108: 1429-37.
    • (2001) J Clin Invest , vol.108 , pp. 1429-1437
    • Takemoto, M.1    Node, K.2    Nakagami, H.3
  • 83
    • 0035141474 scopus 로고    scopus 로고
    • Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes
    • Luo JD, Xie F, Zhang WW, Ma XD, Guan JX, Chen X. Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes. Br J Pharmacol 2001; 132: 159-64.
    • (2001) Br J Pharmacol , vol.132 , pp. 159-164
    • Luo, J.D.1    Xie, F.2    Zhang, W.W.3    Ma, X.D.4    Guan, J.X.5    Chen, X.6
  • 84
    • 33645217659 scopus 로고    scopus 로고
    • Simvastatin inhibits leptin-induced hypertrophy in cultured neonatal rat cardiomyocytes
    • Hu TP, Xu FP, Li YJ, Luo JD. Simvastatin inhibits leptin-induced hypertrophy in cultured neonatal rat cardiomyocytes. Acta Pharmacol Sin 2006; 27: 419-22.
    • (2006) Acta Pharmacol Sin , vol.27 , pp. 419-422
    • Hu, T.P.1    Xu, F.P.2    Li, Y.J.3    Luo, J.D.4
  • 85
    • 0036323450 scopus 로고    scopus 로고
    • Simvastatin prevents angiotensin II-induced cardiac alteration and oxidative stress
    • Delbosc S, Cristol JP, Descomps B, Mimran A, Jover B. Simvastatin prevents angiotensin II-induced cardiac alteration and oxidative stress. Hypertension 2002; 40: 142-7.
    • (2002) Hypertension , vol.40 , pp. 142-147
    • Delbosc, S.1    Cristol, J.P.2    Descomps, B.3    Mimran, A.4    Jover, B.5
  • 87
    • 0342424181 scopus 로고    scopus 로고
    • Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease
    • Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000; 101: 1899-906.
    • (2000) Circulation , vol.101 , pp. 1899-1906
    • Schachinger, V.1    Britten, M.B.2    Zeiher, A.M.3
  • 88
    • 0037007153 scopus 로고    scopus 로고
    • Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: A prospective study
    • Gokce N, Keaney JF, Jr., Hunter LM, Watkins MT, Menzoian JO, Vita JA. Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation 2002; 105: 1567-72.
    • (2002) Circulation , vol.105 , pp. 1567-1572
    • Gokce, N.1    Keaney Jr., J.F.2    Hunter, L.M.3    Watkins, M.T.4    Menzoian, J.O.5    Vita, J.A.6
  • 89
    • 0029007253 scopus 로고
    • Improvement of myocardial perfusion by short-term fluvastatin therapy in coronary artery disease
    • Eichstadt HW, Eskotter H, Hoffman I, Amthauer HW, Weidinger G. Improvement of myocardial perfusion by short-term fluvastatin therapy in coronary artery disease. Am J Cardiol 1995; 76: 122A-5A.
    • (1995) Am J Cardiol , vol.76
    • Eichstadt, H.W.1    Eskotter, H.2    Hoffman, I.3    Amthauer, H.W.4    Weidinger, G.5
  • 90
    • 0031032831 scopus 로고    scopus 로고
    • Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month
    • O'Driscoll G, Green D, Taylor RR. Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month. Circulation 1997; 95: 1126-31.
    • (1997) Circulation , vol.95 , pp. 1126-1131
    • O'Driscoll, G.1    Green, D.2    Taylor, R.R.3
  • 91
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
    • Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990; 322: 1561-6.
    • (1990) N Engl J Med , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 92
    • 0032491201 scopus 로고    scopus 로고
    • Molecular basis of transient outward potassium current downregulation in human heart failure: A decrease in Kv4.3 mRNA correlates with a reduction in current density
    • Kaab S, Dixon J, Duc J, et al. Molecular basis of transient outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density. Circulation 1998; 98: 1383-93.
    • (1998) Circulation , vol.98 , pp. 1383-1393
    • Kaab, S.1    Dixon, J.2    Duc, J.3
  • 93
    • 25444529765 scopus 로고    scopus 로고
    • Molecular physiology of cardiac repolarization
    • Nerbonne JM, Kass RS. Molecular physiology of cardiac repolarization. Physiol Rev 2005; 85: 1205-53.
    • (2005) Physiol Rev , vol.85 , pp. 1205-1253
    • Nerbonne, J.M.1    Kass, R.S.2
  • 94
    • 0034597147 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy
    • Haq S, Choukroun G, Kang ZB, et al. Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy. J Cell Biol 2000; 151: 117-30.
    • (2000) J Cell Biol , vol.151 , pp. 117-130
    • Haq, S.1    Choukroun, G.2    Kang, Z.B.3
  • 96
    • 0037453589 scopus 로고    scopus 로고
    • NFAT transcription factors are critical survival factors that inhibit cardiomyocyte apoptosis during phenylephrine stimulation in vitro
    • Pu WT, Ma Q, Izumo S. NFAT transcription factors are critical survival factors that inhibit cardiomyocyte apoptosis during phenylephrine stimulation in vitro. Circ Res 2003; 92: 725-31.
    • (2003) Circ Res , vol.92 , pp. 725-731
    • Pu, W.T.1    Ma, Q.2    Izumo, S.3
  • 97
    • 12844271214 scopus 로고    scopus 로고
    • Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth
    • Sanna B, Bueno OF, Dai YS, Wilkins BJ, Molkentin JD. Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth. Mol Cell Biol 2005; 25: 865-78.
    • (2005) Mol Cell Biol , vol.25 , pp. 865-878
    • Sanna, B.1    Bueno, O.F.2    Dai, Y.S.3    Wilkins, B.J.4    Molkentin, J.D.5
  • 98
    • 0035853161 scopus 로고    scopus 로고
    • Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo
    • De Windt LJ, Lim HW, Bueno OF, et al. Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo. Proc Natl Acad Sci USA 2001; 98: 3322-7.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3322-3327
    • De Windt, L.J.1    Lim, H.W.2    Bueno, O.F.3
  • 99
    • 0035800041 scopus 로고    scopus 로고
    • Calcineurin plays a critical role in the development of pressure overload-induced cardiac hypertrophy
    • Zou Y, Hiroi Y, Uozumi H, et al. Calcineurin plays a critical role in the development of pressure overload-induced cardiac hypertrophy. Circulation 2001; 104: 97-101.
    • (2001) Circulation , vol.104 , pp. 97-101
    • Zou, Y.1    Hiroi, Y.2    Uozumi, H.3
  • 100
    • 0037155929 scopus 로고    scopus 로고
    • Targeted inhibition of calcineurin in pressure-overload cardiac hypertrophy. Preservation of systolic function
    • Hill JA, Rothermel B, Yoo KD, et al. Targeted inhibition of calcineurin in pressure-overload cardiac hypertrophy. Preservation of systolic function. J Biol Chem 2002; 277: 10251-5.
    • (2002) J Biol Chem , vol.277 , pp. 10251-10255
    • Hill, J.A.1    Rothermel, B.2    Yoo, K.D.3
  • 101
    • 0037154168 scopus 로고    scopus 로고
    • Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo
    • Antos CL, McKinsey TA, Frey N, et al. Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. Proc Natl Acad Sci USA 2002; 99: 907-12.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 907-912
    • Antos, C.L.1    McKinsey, T.A.2    Frey, N.3
  • 102
    • 0037007016 scopus 로고    scopus 로고
    • Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice
    • Bueno OF, Wilkins BJ, Tymitz KM, et al. Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice. Proc Natl Acad Sci USA 2002; 99: 4586-91.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 4586-4591
    • Bueno, O.F.1    Wilkins, B.J.2    Tymitz, K.M.3
  • 103
    • 0037418939 scopus 로고    scopus 로고
    • Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter
    • Sanbe A, Gulick J, Hanks MC, Liang Q, Osinska H, Robbins J. Reengineering inducible cardiac-specific transgenesis with an attenuated myosin heavy chain promoter. Circ Res 2003; 92: 609-16.
    • (2003) Circ Res , vol.92 , pp. 609-616
    • Sanbe, A.1    Gulick, J.2    Hanks, M.C.3    Liang, Q.4    Osinska, H.5    Robbins, J.6
  • 104
    • 0037457958 scopus 로고    scopus 로고
    • Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy
    • Vega RB, Rothermel BA, Weinheimer CJ, et al. Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy. Proc Natl Acad Sci USA 2003; 100: 669-74.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 669-674
    • Vega, R.B.1    Rothermel, B.A.2    Weinheimer, C.J.3
  • 105
    • 2442420976 scopus 로고    scopus 로고
    • MCIP1 overexpression suppresses left ventricular remodeling and sustains cardiac function after myocardial infarction
    • van Rooij E, Doevendans PA, Crijns HJ, et al. MCIP1 overexpression suppresses left ventricular remodeling and sustains cardiac function after myocardial infarction. Circ Res 2004; 94: e18-26.
    • (2004) Circ Res , vol.94
    • van Rooij, E.1    Doevendans, P.A.2    Crijns, H.J.3
  • 106
    • 0347320747 scopus 로고    scopus 로고
    • Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy
    • Wilkins BJ, Dai YS, Bueno OF, et al. Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ Res 2004; 94: 110-8.
    • (2004) Circ Res , vol.94 , pp. 110-118
    • Wilkins, B.J.1    Dai, Y.S.2    Bueno, O.F.3
  • 107
    • 33749014131 scopus 로고    scopus 로고
    • Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy
    • Khoo MS, Li J, Singh MV, et al. Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy. Circulation 2006; 114: 1352-9.
    • (2006) Circulation , vol.114 , pp. 1352-1359
    • Khoo, M.S.1    Li, J.2    Singh, M.V.3
  • 108
    • 33749338744 scopus 로고    scopus 로고
    • Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart
    • Nakayama H, Wilkin BJ, Bodi I, Molkentin JD. Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart. FASEB J 2006; 20: 1660-70.
    • (2006) FASEB J , vol.20 , pp. 1660-1670
    • Nakayama, H.1    Wilkin, B.J.2    Bodi, I.3    Molkentin, J.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.