How to validate a heteromeric ion channel drug target: Assessing proper expression of concatenated subunits

Journal of General Physiology

Volumn 131, Issue 5, 2008, Pages 415-420

  Sack, Jon T ^a   Shamotienko, Oleg ^a   Dolly, J Oliver ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

DRUG TARGETING; ELECTROPHYSIOLOGY; NONHUMAN; PROTEIN EXPRESSION; REVIEW; STOICHIOMETRY;

ANIMALS; BIOMARKERS, PHARMACOLOGICAL; DRUG DESIGN; GENE EXPRESSION; HUMANS; ION CHANNELS; PHARMACEUTICAL PREPARATIONS; PROTEIN ENGINEERING; PROTEIN SUBUNITS;

EID: 42949178643     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200709939     Document Type: Review

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