Synthesis of some thiophene, imidazole and pyridine derivatives exhibiting good anti-inflammatory and analgesic activities

Medicinal Chemistry

Volumn 4, Issue 2, 2008, Pages 146-154

  Sondhi, Sham M ^a   Jain, Shubhi ^a   Dinodia, Monica ^a   Kumar, Ashok ^b  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

^b LLRM MEDICAL COLLEGE   (India)

Author keywords

Analgesic; AnalgesicThiophene; Anti inflammatory; Imidazole; Pyridine; Thiophene

Indexed keywords

(3 IMIDAZOLE 1 YL PROPYL)(5 NITRO THIOPHEN 2 YL METHYLENE)AMINE; 1 (4 CYANOBENZYLIDENE) 2 (PYRIDINE 2 YL)HYDRAZINE; 1 (PYRIDINE 2 YL) 2 (DIMETHOXYBENZYLIDENE) 2 (PYRIDINE 2 YL)HYDRAZINE; 1 (PYRIDINE 2 YL) 2 [(BENZONITRILE 4 YL)ETHYLIDENE]HYDRAZINE; 1 (PYRIDINE 2 YL) 2 [1 (PYRIDINE 4 YL)ETHYLIDENE]HYDRAZINE; 1 [(1H INDOL 3 YL)METHYLENE] 2 (PYRIDINE 2 YL)HYDRAZINE; 2 (1H IMIDAZOL 4 YL) N [1 (PYRIDINE 2 YL)ETHYLIDENE]ETHANAMINE; 2 (1H IMIDAZOL 4 YL) N [1 (PYRIDINYL)ETHYLIDENE]ETHANAMINE; 2,6 BIS(4 METHOXYPHENYL SULFONYL)PYRIDINE 2,6 DICARBOHYDRAZIDE; 2,6 BIS(PHENYL SULFONYL)PYRIDINE 2,6 DICARBOHYDRAZIDE; 2,6 BIS(TOSYL)PYRIDINE 2,6 DICARBOHYDRAZIDE; [2 (1H IMIDAZOL 4 YL) ETHYL] (5 NITRO THIOPHEN 2 YL METHYLENE)AMINE; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; IMIDAZOLE DERIVATIVE; N (5 NITRO THIOPHEN 2 YL METHYLENE) N PYRIDIN 2 YL HYDRAZINE; N (5 NITRO THIOPHEN 2 YL METHYLENE)BENZO[D]TRIOZOL 2 AMINE; N [(5 NITRO THIOPHEN 2 YL)METHYLENE] 3 [4 [3 (5 NITRO THIOPHEN 2 YL)METHYLENE AMINO]PROPYL]PIPERAZINE 1 YL]PROPAN 1 AMINE; PYRIDINE DERIVATIVE; THIOPHENE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; SINGLE HETEROCYCLIC RINGS;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; INFRARED SPECTROMETRY; MASS SPECTROMETRY; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RAT; STRUCTURE ANALYSIS; CHEMISTRY; HUMAN; SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANALGESICS, NON-NARCOTIC; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DRUG EVALUATION, PRECLINICAL; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; IMIDAZOLES; PYRIDINES; SPECTRUM ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 42949131796     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340608783789194     Document Type: Article

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