메뉴 건너뛰기




Volumn 134, Issue 5, 2008, Pages 1555-1566

Polysialylated NCAM Represses E-Cadherin-Mediated Cell-Cell Adhesion in Pancreatic Tumor Cells

Author keywords

[No Author keywords available]

Indexed keywords

NERVE CELL ADHESION MOLECULE; POLYSIALIC ACID; SIALOPROTEIN; SMALL INTERFERING RNA; UVOMORULIN;

EID: 42949129576     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2008.02.023     Document Type: Article
Times cited : (43)

References (47)
  • 1
    • 0026876909 scopus 로고
    • NCAM: structural diversity, function and regulation of expression
    • C. Goridis J.F. Brunet NCAM: structural diversity, function and regulation of expression Semin Cell Biol 3 1992 189 197
    • (1992) Semin Cell Biol , vol.3 , pp. 189-197
    • Goridis, C.1    Brunet, J.F.2
  • 2
    • 0031439129 scopus 로고    scopus 로고
    • Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance
    • F.S. Walsh P. Doherty Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance Annu Rev Cell Dev Biol 13 1997 425 456
    • (1997) Annu Rev Cell Dev Biol , vol.13 , pp. 425-456
    • Walsh, F.S.1    Doherty, P.2
  • 3
    • 0032080661 scopus 로고    scopus 로고
    • Overexpression of a transmembrane isoform of neural cell adhesion molecule alters the invasiveness of rat CNS-1 glioma
    • G.C. Owens E.A. Orr B.K. DeMasters Overexpression of a transmembrane isoform of neural cell adhesion molecule alters the invasiveness of rat CNS-1 glioma Cancer Res 58 1998 2020 2028
    • (1998) Cancer Res , vol.58 , pp. 2020-2028
    • Owens, G.C.1    Orr, E.A.2    DeMasters, B.K.3
  • 4
    • 1442275737 scopus 로고    scopus 로고
    • Distinct roles of different neural cell adhesion molecule (NCAM) isoforms in synaptic maturation revealed by analysis of NCAM 180 kDa isoform-deficient mice
    • L. Polo-Parada C.M. Bose F. Plattner Distinct roles of different neural cell adhesion molecule (NCAM) isoforms in synaptic maturation revealed by analysis of NCAM 180 kDa isoform-deficient mice J Neurosci 24 2004 1852 1864
    • (2004) J Neurosci , vol.24 , pp. 1852-1864
    • Polo-Parada, L.1    Bose, C.M.2    Plattner, F.3
  • 5
  • 6
    • 0034856448 scopus 로고    scopus 로고
    • Roles, regulation, and mechanism of polysialic acid function during neural development
    • J.L. Bruses U. Rutishauser Roles, regulation, and mechanism of polysialic acid function during neural development Biochimie 83 2001 635 643
    • (2001) Biochimie , vol.83 , pp. 635-643
    • Bruses, J.L.1    Rutishauser, U.2
  • 7
    • 0038175079 scopus 로고    scopus 로고
    • Polysialyltransferases: major players in polysialic acid synthesis on the neural cell adhesion molecule
    • K. Angata M. Fukuda Polysialyltransferases: major players in polysialic acid synthesis on the neural cell adhesion molecule Biochimie 85 2003 195 206
    • (2003) Biochimie , vol.85 , pp. 195-206
    • Angata, K.1    Fukuda, M.2
  • 8
    • 0035691179 scopus 로고    scopus 로고
    • Neuroendocrine marker expression in thyroid epithelial tumors
    • F. Satoh S. Umemura M. Yasuda Neuroendocrine marker expression in thyroid epithelial tumors Endocr Pathol 12 2001 291 299
    • (2001) Endocr Pathol , vol.12 , pp. 291-299
    • Satoh, F.1    Umemura, S.2    Yasuda, M.3
  • 9
    • 0035111319 scopus 로고    scopus 로고
    • Expression of neural cell adhesion molecule in pancreatic cancer
    • E. Tezel Y. Kawase S. Takeda Expression of neural cell adhesion molecule in pancreatic cancer Pancreas 22 2001 122 125
    • (2001) Pancreas , vol.22 , pp. 122-125
    • Tezel, E.1    Kawase, Y.2    Takeda, S.3
  • 11
    • 24144436383 scopus 로고    scopus 로고
    • Polysialic acid facilitates tumor invasion by glioma cells
    • M. Suzuki M. Suzuki J. Nakayama Polysialic acid facilitates tumor invasion by glioma cells Glycobiology 15 2005 887 894
    • (2005) Glycobiology , vol.15 , pp. 887-894
    • Suzuki, M.1    Suzuki, M.2    Nakayama, J.3
  • 12
    • 0034212527 scopus 로고    scopus 로고
    • Expression of polysialic acid and STX, a human polysialyltransferase, is correlated with tumor progression in non-small cell lung cancer
    • F. Tanaka Y. Otake T. Nakagawa Expression of polysialic acid and STX, a human polysialyltransferase, is correlated with tumor progression in non-small cell lung cancer Cancer Res 60 2000 3072 3080
    • (2000) Cancer Res , vol.60 , pp. 3072-3080
    • Tanaka, F.1    Otake, Y.2    Nakagawa, T.3
  • 13
    • 0032905654 scopus 로고    scopus 로고
    • Expression of highly polysialylated neural cell adhesion molecule in pancreatic cancer neural invasive lesion
    • K. Kameda H. Shimada T. Ishikawa Expression of highly polysialylated neural cell adhesion molecule in pancreatic cancer neural invasive lesion Cancer Lett 137 1999 201 207
    • (1999) Cancer Lett , vol.137 , pp. 201-207
    • Kameda, K.1    Shimada, H.2    Ishikawa, T.3
  • 14
    • 0142186361 scopus 로고    scopus 로고
    • Expression of polysialylated NCAM on neuroblastomas of various histology and clinical stages
    • S. Gluer M. Zense E. Radtke Expression of polysialylated NCAM on neuroblastomas of various histology and clinical stages Langenbecks Arch Chir Suppl 115 1998 289 292
    • (1998) Langenbecks Arch Chir Suppl , vol.115 , pp. 289-292
    • Gluer, S.1    Zense, M.2    Radtke, E.3
  • 15
    • 13844253424 scopus 로고    scopus 로고
    • Valproic acid modulates NCAM polysialylation and polysialyltransferase mRNA expression in human tumor cells
    • W.D. Beecken T. Engl H. Ogbomo Valproic acid modulates NCAM polysialylation and polysialyltransferase mRNA expression in human tumor cells Int Immunopharmacol 5 2005 757 769
    • (2005) Int Immunopharmacol , vol.5 , pp. 757-769
    • Beecken, W.D.1    Engl, T.2    Ogbomo, H.3
  • 16
    • 0034945537 scopus 로고    scopus 로고
    • N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling
    • U. Cavallaro J. Niedermeyer M. Fuxa N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling Nat Cell Biol 3 2001 650 657
    • (2001) Nat Cell Biol , vol.3 , pp. 650-657
    • Cavallaro, U.1    Niedermeyer, J.2    Fuxa, M.3
  • 17
    • 33845950805 scopus 로고    scopus 로고
    • The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule
    • E. Sanchez-Heras F.V. Howell G. Williams The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule J Biol Chem 281 2006 35208 35216
    • (2006) J Biol Chem , vol.281 , pp. 35208-35216
    • Sanchez-Heras, E.1    Howell, F.V.2    Williams, G.3
  • 18
    • 3442876128 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells
    • C. Veit F. Genze A. Menke Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells Cancer Res 64 2004 5291 5300
    • (2004) Cancer Res , vol.64 , pp. 5291-5300
    • Veit, C.1    Genze, F.2    Menke, A.3
  • 19
    • 0036883940 scopus 로고    scopus 로고
    • Pancreatic cancer biology and genetics
    • N. Bardeesy R.A. DePinho Pancreatic cancer biology and genetics Nat Rev Cancer 2 2002 897 909
    • (2002) Nat Rev Cancer , vol.2 , pp. 897-909
    • Bardeesy, N.1    DePinho, R.A.2
  • 20
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • S. Schubbert K. Shannon G. Bollag Hyperactive Ras in developmental disorders and cancer Nat Rev Cancer 7 2007 295 308
    • (2007) Nat Rev Cancer , vol.7 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 21
    • 16844376315 scopus 로고    scopus 로고
    • Oncogenic Ras in tumour progression and metastasis
    • K. Giehl Oncogenic Ras in tumour progression and metastasis Biol Chem 386 2005 193 205
    • (2005) Biol Chem , vol.386 , pp. 193-205
    • Giehl, K.1
  • 22
    • 0037379779 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular aspects of cancer invasion
    • M. Mareel A. Leroy Clinical, cellular, and molecular aspects of cancer invasion Physiol Rev 83 2003 337 376
    • (2003) Physiol Rev , vol.83 , pp. 337-376
    • Mareel, M.1    Leroy, A.2
  • 23
    • 0025607441 scopus 로고
    • The molecular basis for the assembly and modulation of adherens-type junctions
    • B. Geiger D. Ginsberg D. Salomon The molecular basis for the assembly and modulation of adherens-type junctions Cell Differ Dev 32 1990 343 353
    • (1990) Cell Differ Dev , vol.32 , pp. 343-353
    • Geiger, B.1    Ginsberg, D.2    Salomon, D.3
  • 24
    • 28344433073 scopus 로고    scopus 로고
    • Deconstructing the cadherin-catenin-actin complex
    • S. Yamada S. Pokutta F. Drees Deconstructing the cadherin-catenin-actin complex Cell 123 2005 889 901
    • (2005) Cell , vol.123 , pp. 889-901
    • Yamada, S.1    Pokutta, S.2    Drees, F.3
  • 25
    • 0027507028 scopus 로고
    • Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-Cadherin/β-Catenin complex in cells transformed with a temperature-sensitive v-src gene
    • J. Behrens L. Vakaet R. Friis Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-Cadherin/β-Catenin complex in cells transformed with a temperature-sensitive v-src gene J Cell Biol 120 1993 757 766
    • (1993) J Cell Biol , vol.120 , pp. 757-766
    • Behrens, J.1    Vakaet, L.2    Friis, R.3
  • 26
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • A.K. Perl P. Wilgenbus U. Dahl A causal role for E-cadherin in the transition from adenoma to carcinoma Nature 392 1998 190 193
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3
  • 28
    • 0028170977 scopus 로고
    • Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
    • H. Hoschuetzky H. Aberle R. Kemler Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor J Cell Biol 127 1994 1375 1380
    • (1994) J Cell Biol , vol.127 , pp. 1375-1380
    • Hoschuetzky, H.1    Aberle, H.2    Kemler, R.3
  • 29
    • 0026529501 scopus 로고
    • The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions
    • T. Volberg Y. Zick R. Dror The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions EMBO J 11 1992 1733 1742
    • (1992) EMBO J , vol.11 , pp. 1733-1742
    • Volberg, T.1    Zick, Y.2    Dror, R.3
  • 30
    • 27844478189 scopus 로고    scopus 로고
    • TGF-β-induced down-regulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN
    • R. Vogelmann M.D. Nguyen-tat K. Giehl TGF-β-induced down-regulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN J Cell Sci 118 2005 4901 4912
    • (2005) J Cell Sci , vol.118 , pp. 4901-4912
    • Vogelmann, R.1    Nguyen-tat, M.D.2    Giehl, K.3
  • 31
    • 0035870266 scopus 로고    scopus 로고
    • Down-regulation of E-cadherin gene expression by collagen type I and type III in pancreatic cancer cell lines
    • A. Menke C. Philippi R. Vogelmann Down-regulation of E-cadherin gene expression by collagen type I and type III in pancreatic cancer cell lines Cancer Res 61 2001 3508 3517
    • (2001) Cancer Res , vol.61 , pp. 3508-3517
    • Menke, A.1    Philippi, C.2    Vogelmann, R.3
  • 32
    • 1142286408 scopus 로고    scopus 로고
    • Expression profiling of the influence of RAS mutants on the TGFβ1-induced phenotype of the pancreatic cancer cell line PANC-1
    • H. Fensterer K. Giehl M. Buchholz Expression profiling of the influence of RAS mutants on the TGFβ1-induced phenotype of the pancreatic cancer cell line PANC-1 Genes Chromosomes Cancer 39 2004 224 235
    • (2004) Genes Chromosomes Cancer , vol.39 , pp. 224-235
    • Fensterer, H.1    Giehl, K.2    Buchholz, M.3
  • 33
    • 33646361573 scopus 로고    scopus 로고
    • Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38
    • U. Dreissigacker M.S. Mueller M. Unger Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38 Cell Signal 18 2006 1156 1168
    • (2006) Cell Signal , vol.18 , pp. 1156-1168
    • Dreissigacker, U.1    Mueller, M.S.2    Unger, M.3
  • 34
    • 0029073956 scopus 로고
    • Molecular cloning and functional expression of bacteriophage PK1E-encoded endoneuraminidase Endo NE
    • R. Gerardy-Schahn A. Bethe T. Brennecke Molecular cloning and functional expression of bacteriophage PK1E-encoded endoneuraminidase Endo NE Mol Microbiol 16 1995 441 450
    • (1995) Mol Microbiol , vol.16 , pp. 441-450
    • Gerardy-Schahn, R.1    Bethe, A.2    Brennecke, T.3
  • 35
    • 0038459055 scopus 로고    scopus 로고
    • A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform
    • B. Sipos S. Moser H. Kalthoff A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform Virchows Arch 442 2003 444 452
    • (2003) Virchows Arch , vol.442 , pp. 444-452
    • Sipos, B.1    Moser, S.2    Kalthoff, H.3
  • 36
    • 0028109165 scopus 로고
    • Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer
    • G. Berrozpe J. Schaeffer M.A. Peinado Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer Int J Cancer 58 1994 185 191
    • (1994) Int J Cancer , vol.58 , pp. 185-191
    • Berrozpe, G.1    Schaeffer, J.2    Peinado, M.A.3
  • 37
    • 0042131904 scopus 로고    scopus 로고
    • Polysialic acid directs tumor cell growth by controlling heterophilic neural cell adhesion molecule interactions
    • R. Seidenfaden A. Krauter F. Schertzinger Polysialic acid directs tumor cell growth by controlling heterophilic neural cell adhesion molecule interactions Mol Cell Biol 23 2003 5908 5918
    • (2003) Mol Cell Biol , vol.23 , pp. 5908-5918
    • Seidenfaden, R.1    Krauter, A.2    Schertzinger, F.3
  • 38
    • 12844285655 scopus 로고    scopus 로고
    • Direct evidence that neural cell adhesion molecule (NCAM) polysialylation increases intermembrane repulsion and abrogates adhesion
    • C.P. Johnson I. Fujimoto U. Rutishauser Direct evidence that neural cell adhesion molecule (NCAM) polysialylation increases intermembrane repulsion and abrogates adhesion J Biol Chem 280 2005 137 145
    • (2005) J Biol Chem , vol.280 , pp. 137-145
    • Johnson, C.P.1    Fujimoto, I.2    Rutishauser, U.3
  • 39
    • 0345435966 scopus 로고    scopus 로고
    • Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets
    • F. Esni I.B. Taljedal A.K. Perl Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets J Cell Biol 144 1999 325 337
    • (1999) J Cell Biol , vol.144 , pp. 325-337
    • Esni, F.1    Taljedal, I.B.2    Perl, A.K.3
  • 40
    • 10844287931 scopus 로고    scopus 로고
    • Zippers make signals: NCAM-mediated molecular interactions and signal transduction
    • P.S. Walmod K. Kolkova V. Berezin Zippers make signals: NCAM-mediated molecular interactions and signal transduction Neurochem Res 29 2004 2015 2035
    • (2004) Neurochem Res , vol.29 , pp. 2015-2035
    • Walmod, P.S.1    Kolkova, K.2    Berezin, V.3
  • 41
    • 0035943669 scopus 로고    scopus 로고
    • Regulation of cell adhesion by polysialic acid: Effects on cadherin, immunoglobulin cell adhesion molecule, and integrin function and independence from neural cell adhesion molecule binding or signaling activity
    • I. Fujimoto J.L. Bruses U. Rutishauser Regulation of cell adhesion by polysialic acid Effects on cadherin, immunoglobulin cell adhesion molecule, and integrin function and independence from neural cell adhesion molecule binding or signaling activity J Biol Chem 276 2001 31745 31751
    • (2001) J Biol Chem , vol.276 , pp. 31745-31751
    • Fujimoto, I.1    Bruses, J.L.2    Rutishauser, U.3
  • 42
    • 0030270037 scopus 로고    scopus 로고
    • Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell-cell interactions
    • U. Rutishauser L. Landmesser Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell-cell interactions Trends Neurosci 19 1996 422 427
    • (1996) Trends Neurosci , vol.19 , pp. 422-427
    • Rutishauser, U.1    Landmesser, L.2
  • 43
    • 0026522352 scopus 로고
    • Intercellular space is affected by the polysialic acid content of NCAM
    • P. Yang X. Yin U. Rutishauser Intercellular space is affected by the polysialic acid content of NCAM J Cell Biol 116 1992 1487 1496
    • (1992) J Cell Biol , vol.116 , pp. 1487-1496
    • Yang, P.1    Yin, X.2    Rutishauser, U.3
  • 44
    • 0028133113 scopus 로고
    • Role of charge and hydration in effects of polysialic acid on molecular interactions on and between cell membranes
    • P. Yang D. Major U. Rutishauser Role of charge and hydration in effects of polysialic acid on molecular interactions on and between cell membranes J Biol Chem 269 1994 23039 23044
    • (1994) J Biol Chem , vol.269 , pp. 23039-23044
    • Yang, P.1    Major, D.2    Rutishauser, U.3
  • 45
    • 0031888316 scopus 로고    scopus 로고
    • Distribution of N-cadherin and NCAM in neurons and endocrine cells of the human embryonic and fetal gastroenteropancreatic system
    • Y.A. Gaidar E.A. Lepekhin G.A. Sheichetova Distribution of N-cadherin and NCAM in neurons and endocrine cells of the human embryonic and fetal gastroenteropancreatic system Acta Histochem 100 1998 83 97
    • (1998) Acta Histochem , vol.100 , pp. 83-97
    • Gaidar, Y.A.1    Lepekhin, E.A.2    Sheichetova, G.A.3
  • 46
    • 0030887348 scopus 로고    scopus 로고
    • NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn)
    • H.E. Beggs S.C. Baragona J.J. Hemperly NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn) J Biol Chem 272 1997 8310 8319
    • (1997) J Biol Chem , vol.272 , pp. 8310-8319
    • Beggs, H.E.1    Baragona, S.C.2    Hemperly, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.