Valproic acid modulates NCAM polysialylation and polysialyltransferase mRNA expression in human tumor cells

International Immunopharmacology

Volumn 5, Issue 4, 2005, Pages 757-769

  Beecken, Wolf Dietrich ^a   Engl, Tobias ^a   Ogbomo, Henry ^a   Relja, Borna ^a   Cinatl, Jindrich ^a   Bereiter Hahn, Jürgen ^a   Oppermann, Elsie ^a   Jonas, Dietger ^a   Blaheta, Roman A ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

PSA NCAM; ST8SiaII; ST8SiaIV; Tumor dissemination; Valproic acid

Indexed keywords

MESSENGER RNA; NERVE CELL ADHESION MOLECULE; POLYSIALYLTRANSFERASE MRNA; RNA DERIVATIVE; UNCLASSIFIED DRUG; VALPROIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOACCUMULATION; CANCER CELL CULTURE; CELL SURFACE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NEUROECTODERM TUMOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIALYLATION; UMBILICAL VEIN; UPREGULATION;

EID: 13844253424     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2004.12.009     Document Type: Article

References (40)

1. R.A. Blaheta, H. Nau, M. Michaelis, and J. Cinatl Jr. Valproate and valproate-analogues: potent tools to fight against cancer Curr. Med. Chem. 9 2002 1417 1433
2. J. Cinatl Jr., R. Kotchetkov, R. Blaheta, P.H. Driever, J.U. Vogel, and J. Cinatl Induction of differentiation and suppression of malignant phenotype of human neuroblastoma BE(2)-C cells by valproic acid: enhancement by combination with interferon-alpha Int. J. Oncol. 20 2002 97 106
3. J. Cinatl Jr., J. Cinatl, M. Scholz, P.H. Driever, D. Henrich, and H. Kabickova Antitumor activity of sodium valproate in cultures of human neuroblastoma cells Anticancer Drugs 7 1996 766 773
4. J. Cinatl Jr., J. Cinatl, P.H. Driever, R. Kotchetkov, P. Pouckova, and B. Kornhuber Sodium valproate inhibits in vivo growth of human neuroblastoma cells Anticancer Drugs 8 1997 958 963
5. M.M. Knupfer, P. Hernaiz-Driever, H. Poppenborg, J.E. Wolff, and J. Cinatl Valproic acid inhibits proliferation and changes expression of CD44 and CD56 of malignant glioma cells in vitro Anticancer Res. 18 1998 3585 3589
6. G. Skladchikova, V. Berezin, and E. Bock Valproic acid, but not its non-teratogenic analogue 2-isopropylpentanoic acid, affects proliferation, viability and neuronal differentiation of the human teratocarcinoma cell line NTera-2 Neurotoxicology 19 1998 357 370
7. R.A. Blaheta, M. Hundemer, G. Mayer, J.U. Vogel, B. Kornhuber, and J. Cinatl Expression level of neural cell adhesion molecule (NCAM) inversely correlates with the ability of neuroblastoma cells to adhere to endothelium in vitro Cell Commun. Adhes. 9 2002 131 147
8. G.C. Owens, E.A. Orr, B.K. DeMasters, R.J. Muschel, M.E. Berens, and C.A. Kruse Overexpression of a transmembrane isoform of neural cell adhesion molecule alters the invasiveness of rat CNS-1 glioma Cancer Res. 58 1998 2020 2028
9. S. Prag, E.A. Lepekhin, K. Kolkova, R. Hartmann-Petersen, A. Kawa, and P.S. Walmod NCAM regulates cell motility J. Cell Sci. 115 2002 283 292
10. K. Edvardsen, P.-H. Pedersen, R. Bjerkvig, G.G. Hermann, J. Zeuthen, and O.D. Laerum Transfection of glioma cells with the neural-cell adhesion molecule NCAM: effect on glioma cell invasion and growth in vivo Int. J. Cancer 58 1994 116 122
11. S. Huerta, E.S. Srivatsan, N. Venkatesan, J. Peters, F. Moatamed, and S. Renner Alternative mRNA splicing in colon cancer causes loss of expression of neural cell adhesion molecule Surgery 130 2001 834 843
12. J. Roesler, E. Srivatsan, F. Moatamed, J. Peters, and E.H. Livingston Tumor suppressor activity of neural cell adhesion molecule in colon carcinoma Am. J. Surg. 174 1997 251 257
13. A. Sampson-Johannes, W. Wang, and E. Shtivelman Colonization of human lung grafts in SCID-hu mice by human colon carcinoma cells Int. J. Cancer 65 1996 864 869
14. U. Cavallaro, J. Niedermeyer, M. Fuxa, and G. Christofori N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling Nat. Cell Biol. 3 2001 650 657
15. A.K. Perl, U. Dahl, P. Wilgenbus, H. Cremer, H. Semb, and G. Christofori Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells Nat. Med. 5 1999 286 291
16. E. Tezel, Y. Kawase, S. Takeda, K. Oshima, and A. Nakao Expression of neural cell adhesion molecule in pancreatic cancer Pancreas 22 2001 122 125
17. M. Mühlenhoff, M. Eckhardt, and R. Gerardy-Schahn Polysialic acid: three-dimensional structure, biosynthesis and function Curr. Opin. Struct. Biol. 8 1998 558 564
18. P. Durbec, and H. Cremer Revisiting the function of PSA-NCAM in the nervous system Mol. Neurobiol. 24 2001 53 64
19. U. Rutishauser, and L. Landmesser Polysialic acid in the vertebrate nervous system-a promoter of plasticity in cell-cell interactions Trends Neurosci. 19 1996 422 427
20. D.F. Figarella Branger, P.L. Durbec, and G.N. Rougon Differential spectrum of expression of neural cell adhesion molecule isoforms and L1 adhesion molecules on human neuroectodermal tumors Cancer Res. 50 1990 6364 6370
21. M. Fukuda Possible roles of tumor-associated carbohydrate antigens Cancer Res. 56 1996 2237 2244
22. S. Glüer, C. Schelp, N. Madry, D. Von Schweinitz, M. Eckhardt, and R. Gerardy-Schahn Serum polysialylated neural cell adhesion molecule in childhood neuroblastoma Br. J. Cancer 78 1998 106 110
23. S. Glüer, C. Schelp, D. Von Schweinitz, and R. Gerardy-Schahn Polysialylated neural cell adhesion molecule in childhood rhabdomyosarcoma Pediatr. Res. 43 1998 145 147
24. F. Tanaka, Y. Otake, T. Nakagawa, Y. Kawano, R. Miyahara, and M. Li Prognostic significance of polysialic acid expression in resected nonsmall cell lung cancer Cancer Res. 61 2001 1666 1670
25. R. Seidenfaden, R. Gerardy-Schahn, and H. Hildebrandt Control of NCAM polysialylation by the differential expression of polysialyltransferases ST8SiaII and ST8SiaIV Eur. J. Cell Biol. 79 2000 680 688
26. J. Cinatl Jr., J. Cinatl, R. Kotchetkov, J.U. Vogel, B.G. Woodcock, and J. Matousek Bovine seminal ribonuclease selectively kills human multidrug-resistant neuroblastoma cells via induction of apoptosis Int. J. Oncol. 15 1999 1001 1009
27. R. Seidenfaden, and H. Hildebrandt Retinoic acid-induced changes in polysialyltransferase mRNA expression and NCAM polysialylation in human neuroblastoma cells J. Neurobiol. 46 2001 11 28
28. G.L. Poongodi, N. Suresh, S.C. Gopinath, T. Chang, S. Inoue, and Y. Inoue Dynamic change of neural cell adhesion molecule polysialylation on human neuroblastoma (IMR-32) and rat pheochromocytoma (PC-12) cells during growth and differentiation J. Biol. Chem. 277 2002 28200 28211
29. M. Husmann, I. Gorgen, C. Weisgerber, and D. Bitter-Suermann Up-regulation of embryonic NCAM in an EC cell line by retinoic acid Dev. Biol. 136 1989 194 200
30. T. Nubel, W. Dippold, B. Kaina, and G. Fritz Ionizing radiation-induced E-selectin gene expression and tumor cell adhesion is inhibited by lovastatin and all-trans retinoic acid Carcinogenesis 25 2004 1335 1344
31. F. Liu, H.L. Qi, and H.L. Chen Regulation of differentiation- and proliferation-inducers on Lewis antigens, alpha-fucosyltransferase and metastatic potential in hepatocarcinoma cells Br. J. Cancer 84 2001 1556 1563
32. L. Daniel, P. Durbec, E. Gautherot, E. Rouvier, G. Rougon, and D. Figarella-Branger A nude mice model of human rhabdomyosarcoma lung metastases for evaluating the role of polysialic acids in the metastatic process Oncogene 20 2001 997 1004
33. L. Daniel, J. Trouillas, W. Renaud, P. Chevallier, J. Gouvernet, and G. Rougon Polysialylated-neural cell adhesion molecule expression in rat pituitary transplantable tumors (spontaneous mammotropic transplantable tumor in Wistar-Furth rats) is related to growth rate and malignancy Cancer Res. 60 2000 80 85
34. S. Lantuejoul, D. Moro, R.J. Michalides, C. Brambilla, and E. Brambilla Neural cell adhesion molecules (NCAM) and NCAM-PSA expression in neuroendocrine lung tumors Am. J. Surg. Pathol. 22 1998 1267 1276
35. T. Jimbo, J. Nakayama, K. Akahane, and M. Fukuda Effect of polysialic acid on the tumor xenografts implanted into nude mice Int. J. Cancer 94 2001 192 199
36. R. Horstkorte, N. Lessner, R. Gerardy-Schahn, L. Lucka, K. Danker, and W. Reutter Expression of the polysialyltransferase ST8SiaIV: polysialylation interferes with adhesion of PC12 cells in vitro Exp. Cell Res. 246 1999 122 128
37. K. Angata, M. Suzuki, and M. Fukuda Differential and cooperative polysialylation of the neural cell adhesion molecule by two polysialyltransferases, PST and STX J. Biol. Chem. 273 1998 28524 28532
38. C.S. Mayanil, D. George, B. Mania-Farnell, C.L. Bremer, D.G. McLone, and E.G. Bremer Overexpression of murine Pax3 increases NCAM polysialylation in a human medulloblastoma cell line J. Biol. Chem. 275 2000 23259 23266
39. F. Tanaka, Y. Otake, T. Nakagawa, Y. Kawano, R. Miyahara, and M. Li Expression of polysialic acid and STX, a human polysialyltransferase, is correlated with tumor progression in non-small cell lung cancer Cancer Res. 60 2000 3072 3080
40. N. Kojima, Y. Tachida, and S. Tsuji Two polysialic acid synthases, mouse ST8Sia II and IV, synthesize different degrees of polysialic acids on different substrate glycoproteins in mouse neuroblastoma Neuro2a cells J. Biochem. 122 1997 1265 1273