Vaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine

Virology

Volumn 374, Issue 2, 2008, Pages 261-272

  Sparger, Ellen E ^a   Dubie, Robert A ^a   Shacklett, Barbara L ^b   Cole, Kelly S ^c   Chang, W L ^a   Luciw, Paul A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

DNA vaccine; Immunogenicity; SIV; vif

Indexed keywords

DNA VACCINE; VIF PROTEIN;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA IMMUNIZATION; ENZYME LINKED IMMUNOSPOT ASSAY; EXPERIMENTAL INFECTION; FEMALE; IMMUNOGENICITY; INFECTION PREVENTION; INOCULATION; MONKEY DISEASE; NONHUMAN; OVERALL SURVIVAL; PLASMID; PRIORITY JOURNAL; PROVIRUS; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; SPECIES COMPARISON; SURVIVAL TIME; T LYMPHOCYTE ACTIVATION; VIRUS INHIBITION; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; ANTIBODIES, VIRAL; CELL LINE; FEMALE; GENE DELETION; GENE PRODUCTS, VIF; GENES, VIF; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MACACA MULATTA; PROVIRUSES; SAIDS VACCINES; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES; VACCINATION; VACCINES, ATTENUATED; VACCINES, DNA;

ANIMALIA; LENTIVIRUS; MACACA; MACACA MULATTA; PRIMATES; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 42749094185     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.01.020     Document Type: Article

References (52)

1. Abel K., Compton L., Rourke T., Montefiori D., Lu D., Rothaeusler K., Fritts L., Bost K., and Miller C.J. Simian-human immunodeficiency virus SHIV89.6-induced protection against intravaginal challenge with pathogenic SIVmac239 is independent of the route of immunization and is associated with a combination of cytotoxic T-lymphocyte and alpha interferon responses. J. Virol 77 (2003) 3099-3118
2. Akahata W., Ido E., Shimada T., Katsuyama K., Yamamoto H., Uesaka H., Ui M., Kuwata T., Takahashi H., and Hayami M. DNA vaccination of macaques by a full genome HIV-1 plasmid which produces noninfectious virus particles. Virology 275 (2000) 116-124
3. Almond N., and Stott J. Live attenuated SIV-a model of a vaccine for AIDS. Immunol. Lett 66 (1999) 167-170
4. Baba T.W., Jeong Y.S., Pennick D., Bronson R., Greene M.F., and Ruprecht R.M. Pathogenicity of live attenuated SIV after mucosal infection of neonatal macaques. Science 267 (1995) 1820-1825
5. Baba T.W., Liska V., Khimani A.H., Ray N.B., Dailey P.J., Penninck D., Bronson R., Greene M.F., McClure H.M., Martin L.N., and Ruprecht R.M. Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques. Nat. Med 5 (1999) 194-203
6. Bayry J., Triebel F., Kaveri S.V., and Tough D.F. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+regulatory T cells. J. Immunol 178 (2007) 4184-4193
7. Brenchley J.M., Hill B.J., Ambrozak D.R., Price D.A., Guenaga F.J., Casazza J.P., Kuruppu J., Yazdani J., Migueles S.A., Connors M., Roederer M., Douek D.C., and Koup R.A. T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis. J. Virol 78 (2004) 1160-1168
8. Brenchley J.M., Ruff L.E., Casazza J.P., Koup R.A., Price D.A., and Douek D.C. Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo. J. Virol 80 (2006) 6801-6809
9. Cole K.S., Rowles J.L., Jagerski B.A., Murphey-Corb M., Unangst T., Clements J.E., Robinson J., Wyand M.S., Desrosiers R.C., and Montelaro R.C. Evolution of envelope-specific antibody responses in monkeys experimentally infected or immunized with simian immunodeficiency virus and its association with the development of protective immunity. J. Virol 71 (1997) 5069-5079
10. Cullen B.R. Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors. J. Virol 80 (2006) 1067-1076
11. Daniel M.D., Kirchhoff F., Czajak S.C., Sehgal P.K., and Desrosiers R.C. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258 (1992) 1938-1941
12. Desrosiers R.C., Lifson J.D., Gibbs J.S., Czajak S.C., Howe A.Y., Arthur L.O., and Johnson R.P. Identification of highly attenuated mutants of simian immunodeficiency virus. J. Virol 72 (1998) 1431-1437
13. Douek D.C., Brenchley J.M., Betts M.R., Ambrozak D.R., Hill B.J., Y.O., Casazza J.P., Kuruppu J., Kunstman K., Wolinsky S., Grossman Z., Dybul M., Oxenius A., Price D.A., Connors M., and Koup R.A. HIV preferentially infects HIV-specific CD4+ T cells. Nature 417 (2002) 95-98
14. Frank I., Santos J.J., Mehlhop E., Villamide-Herrera L., Santisteban C., Gettie A., Ignatius R., Lifson J.D., and Pope M. Presentation of exogenous whole inactivated simian immunodeficiency virus by mature dendritic cells induces CD4+ and CD8+ T-cell responses. J. Acquir. Immune Defic. Syndr 334 (2003) 7-19
15. Gabuzda D.H., Li H., Lawrence K., Vasir B.S., Crawford K., and Langhoff E. Essential role of vif in establishing productive HIV-1 infection in peripheral blood T lymphocytes and monocyte/macrophages. J. Acquir. Immune Defic. Syndr 7 (1994) 908-915
16. Galvin T.A., Muller J., and Khan A.S. Effect of different promoters on immune responses elicited by HIV-1 gag/Env multigenic DNA vaccine in Macaca mulatta and Macaca nemestrina. Vaccine 18 (2000) 2566-2583
17. Gauduin M.C., Glickman R.L., Ahmad S., Yilma T., Johnson, and R.P. Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and beta-chemokine production. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 14031-14036
18. Gauduin M.C., Yu Y., Barabasz A., Carville A., Piatak M., Lifson J.D., Desrosiers R.C., and Johnson R.P. Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection. J. Exp. Med 203 (2006) 2661-2672
19. Gemeniano M.C., Sawai E.T., and Sparger E.E. Feline immunodeficiency virus Orf-A localizes to the nucleus and induces cell cycle arrest. Virology 325 (2004) 167-174
20. Giri M., Ugen K.E., and Weiner D.B. DNA vaccines against human immunodeficiency virus type 1 in the past decade. Clin. Microbiol. Rev 17 (2004) 370-389
21. Gorelick R.J., Benveniste R.E., Lifson J.D., Yovandich J.L., Morton W.R., Kuller L., Flynn B.M., Fisher B.A., Rossio J.L., Piatak M., Bess J.W., Henderson L.E., and Arthur L.O. Protection of Macaca nemestrina from disease following pathogenic simian immunodeficiency virus challenge: utilization of SIV nucleocapsid mutant DNA vaccines with and without an SIV boost. J. Virol 74 (2000) 11935-11949
22. Gupta S., Leutenegger C.M., Dean G.A., Steckbeck J.D., Cole K.S., and Sparger E.E. Vaccination of cats with attenuated feline immunodeficiency virus proviral DNA vaccine expressing gamma interferon. J. Virol 81 (2007) 465-473
23. Harari A., Rizzardi G.P., Ellefsen K., Ciuffreda D., Champagne P., Bart P.A., Kaufmann D., Telenti A., Sahli R., Tambussi G., Kaiser L., Lazzarin A., Perrin L., and Pantaleo G. Analysis of HIV-1-and CMV-specific memory CD4 T-cell responses during primary and chronic infection. Blood 100 (2002) 1381-1387
24. Harmache A., Russo P., Guiguen F., Vitu C., Vignoni M., Bouyac M., Hieblot C., Pepin M., Vigne R., and Suzan M. Requirement of caprine arthritis encephalitis virus vif gene for in vivo replication. Virology 224 (1996) 246-255
25. Himathongkham S., Douglas G.C., Fang A., Yu E., Barnett S.W., and Luciw P.A. Species tropism of chimeric SHIV clones containing HIV-1 subtype-A and subtype-E envelope genes. Virology 298 (2002) 189-199
26. Hofmann-Lehmann R., Vlasak J., Williams A.L., Chenine A.L., McClure H.M., Anderson D.C., O'Neil S., and Ruprecht R.M. Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation. AIDS 17 (2003) 157-166
27. Hokey D.A., and Weiner D.B. DNA vaccines for HIV: challenges and opportunities. Springer Semin. Immunopathol. 28 (2006) 267-279
28. Inoshima Y., Kohmoto M., Ikeda Y., Yamada H., Kawaguchi Y., Tomonaga K., Miyazawa T., Kai C., Umemura T., and Mikami T. Roles of the auxiliary genes and AP-1 binding site in the long terminal repeat of feline immunodeficiency virus in the early stage of infection in cats. J. Virol 70 (1996) 8518-8526
29. Johnson R.P., Lifson J.D., Czajak S.C., Cole K.S., Manson K.H., Glickman R., Yang J., Montefiori D.C., Montelaro R., Wyand M.S., and Desrosiers R.C. Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation. J. Virol 73 (1999) 4952-4961
30. Kristbjornsdottir H.B., Andresdottir V., Svansson V., Torsteinsdottir S., Matthiasdottir S., and Andresson O.S. The vif gene of maedi-visna virus is essential for infectivity in vivo and in vitro. Virology 318 (2004) 350-359
31. Larsson M., Jin X., Ramratnam B., Ogg G.S., Engelmayer J., Demoitie M.A., McMichael A.J., Cox W.I., Steinman R.M., Nixon D., and Bhardwaj N. A recombinant vaccinia virus based ELISPOT assay detects high frequencies of Pol-specific CD8 T cells in HIV-1-positive individuals. AIDS 13 (1999) 767-777
32. Letvin N.L. Progress and obstacles in the development of an AIDS vaccine. Nat. Rev. Immunol 6 (2006) 930-939
33. Leutenegger C.M., Higgins J., Matthews T., Tarantal A.F., Luciw P.A., Pedersen N.C., and North T.W. Real-time TaqMan® PCR as a specific and more sensitive alternative to the branched-chain DNA assay for quantitation of simian immunodeficiency virus RNA. AIDS Res. Hum. Retroviruses 17 (2001) 243-251
34. Liu Z., Singh D.K., Sheffer D., Smith M.S., Dhillon S., Chebloune Y., Hegde R., Buch S., and Narayan O. Immunoprophylaxis against AIDS in macaques with a lentiviral DNA vaccine. Virology 351 (2006) 444-454
35. Lockridge K.M., Himathongkham S., Sawai E.T., Chienand M., and Sparger E.E. The feline immunodeficiency virus vif gene is required for productive infection of feline peripheral blood mononuclear cells and monocyte-derived macrophages. Virology 261 (1999) 25-30
36. Lockridge K., Chien M., Luciw P.A., Sparger, and E.E. Protective immunity against feline immunodeficiency virus induced by inoculation with vif-deleted proviral DNA. Virology 273 (2000) 67-79
37. Lohman B.L., McChesney M.B., Miller C.J., McGowan E., Joye S.M., Van Rompay K., Reay E., Antipa L., Pedersen N., and Marthas M.L. A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge. J. Virol 68 (1994) 7021-7029
38. Lori F., Weiner D.B., Calarota S.A., Kelly L.M., and Lisziewicz J. Cytokine-adjuvanted HIV-DNA vaccination strategies. Springer Semin. Immunopathol 28 (2006) 231-238
39. Ma Z.M., Abel K., Rourke T., Wang Y., and Miller C.J. A period of transient viremia and occult infection precedes persistent viremia and antiviral immune responses during multiple low-dose intravaginal simian immunodeficiency virus inoculations. J. Virol 78 (2004) 14048-14052
40. Manthorpe M., Cornefert-Jensen F., Hartikka J., Felgner J., Rundell A., Margalith M., and Dwarki V. Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice. Hum. Gene Ther 4 (1993) 419-431
41. Marthas M.L., Lu D., Penedo M.C., Hendrickx A.G., and Miller C.J. Titration of an SIVmac251 stock by vaginal inoculation of Indian and Chinese origin rhesus macaques: transmission efficiency, viral loads, and antibody responses. AIDS Res. Hum. Retroviruses 17 (2001) 1455-1466
42. McChesney M.B., Collins J.R., Lu D., Lü X., Torten J., Ashley R.L., Cloyd M.W., and Miller C.J. Occult systemic infection and persistent SIV-specific CD4+ T cell proliferative responses in rhesus macaques that were transiently viremic after intravaginal inoculation of SIV. J. Virol 72 (1998) 10029-10035
43. O'Connor D.H., Mothe B.R., Weinfurter J.T., Fuenger S., Rehrauer W.M., Jing P., Rudersdorf R.R., Liebl M.E., Krebs K., Vasquez J., Dodds E., Loffredo J., Martin S., McDermott A.B., Allen T.M., Wang C., Doxiadis G.G., Montefiori D.C., Hughes A., Burton D.R., Allison D.B., Wolinsky S.M., Bontrop R., Picker L.J., and Watkins D.I. Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses. J. Virol 77 (2003) 9029-9040
44. Ruprecht R.M., Baba T.W., Rasmussen R., Hu Y., and Sharma P.L. Murine and simian retrovirus models: the threshold hypothesis. Aids 10 (1996) S33-S40
45. Rutebemberwa A., Bess J.W.J., Brown B., Arroyo M., Eller M., Slike B., Polonis V., McCutchan F., Currier J.R., Birx D., Robb M., Marovich M., Lifson J.D., and Cox J.H. Evaluation of aldrithiol-2-inactivated preparations of HIV type 1 subtypes A, B, and D as reagents to monitor T cell responses. AIDS Res. Hum. Retroviruses 23 (2007) 532-542
46. Shacklett B.L., Shaw K.E., Adamson L.A., Wilkens D.T., Cox C.A., Montefiori D.C., Gardner M.B., Sonigo P., and Luciw P.A. Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251. J. Virol 76 (2002) 11365-11378
47. Singh D.K., Liu Z., Sheffer D., Mackay G.A., Smith M., Dhillon S., Hegde R., Jia F., Adany I., and Narayan O. A noninfectious simian/human immunodeficiency virus DNA vaccine that protects macaques against AIDS. J. Virol 79 (2005) 3419-3428
48. Spörri R., and Reis e Sousa C. Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nat. Immunol 6 (2007) 163-170
49. Wang S., Kozlowski P.A., Achmelz G., Manson K., Wyand M.S., Glickman R., Montefiori D., Lifson J.D., Johnson R.P., Neutra M.R., and Aldovini A. Effective induction of simian immunodeficiency virus-specific systemic and mucosal immune responses in primates by vaccination with proviral DNA producing intact but noninfectious virions. J. Virol 74 (2000) 10514-10522
50. *17-containing haplotypes. J. Virol 81 (2007) 406-410
51. *17 is associated with control of simian immunodeficiency virus SIVmac239 replication. J. Virol 80 (2006) 5074-5077
52. Zou J.X., and Luciw P.A. The requirement for vif of SIVmac is cell-type dependent. J. Gen. Virol 77 (1996) 427-434