Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk

Journal of Allergy and Clinical Immunology

Volumn 121, Issue 5, 2008, Pages 1225-1231

  Lee, Jun Ho ^a   Kim, Jie Wan ^a   Ko, Na Young ^a   Mun, Se Hwan ^a   Her, Erk ^a   Kim, Bo Kyung ^a   Han, Jeung Whan ^b   Lee, Hoi Young ^c   Beaven, Michael A ^d   Kim, Young Mi ^e   Choi, Wahn Soo ^a  

^a Konkuk University   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Konyang University   (South Korea)

^d NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^e Duksung Women's University   (South Korea)

Author keywords

allergy; curcumin; Curry spice; IgE; mast cells; passive cutaneous anaphylaxis; Syk kinase

Indexed keywords

CURCUMIN; IMMUNOGLOBULIN E; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE SYK; PROTEIN P42; PROTEIN P44; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DRUG INHIBITION; IN VIVO STUDY; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTI-ALLERGIC AGENTS; BLOTTING, WESTERN; CELL DEGRANULATION; CURCUMIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPERSENSITIVITY; IMMUNOGLOBULIN E; IMMUNOPRECIPITATION; INTERLEUKIN-4; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; PASSIVE CUTANEOUS ANAPHYLAXIS; PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 42749083630     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.12.1160     Document Type: Article

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