Phenomena of insulin peak fronting in size exclusion chromatography and strategies to reduce fronting

Journal of Chromatography A

Volumn 1192, Issue 1, 2008, Pages 121-129

  Yu, Chi Ming ^b   Mun, Sungyong ^c   Wang, Nien Hwa Linda ^a  

^a Purdue University   (United States)

^b Xencor Inc   (United States)

^c Hanyang University   (South Korea)

Author keywords

Insulin; Peak fronting; Reversible insulin association; Size exclusion chromatography; Strategies to reduce fronting

Indexed keywords

ACETIC ACID; DIMERIZATION; MATHEMATICAL MODELS; PURIFICATION; SIZE EXCLUSION CHROMATOGRAPHY;

PEAK FRONTING; REVERSIBLE INSULIN ASSOCIATION; STRATEGIES TO REDUCE FRONTING;

INSULIN;

ACETIC ACID; INSULIN; METHYLATED SPIRIT;

ADSORPTION; ANALYTIC METHOD; ARTICLE; DENATURATION; DIMERIZATION; ELUTION; GEL PERMEATION CHROMATOGRAPHY; INSULIN SYNTHESIS; MOLECULAR MODEL; PHASE SEPARATION; PRIORITY JOURNAL; REDUCTION; SEPARATION TECHNIQUE; VISCOSITY;

ACETIC ACID; ADSORPTION; CHROMATOGRAPHY, GEL; DIMERIZATION; ETHANOL; INSULIN;

EID: 42649127101     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.03.055     Document Type: Article

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