Separation of FTC-ester enantiomers using a simulated moving bed

Industrial and Engineering Chemistry Research

Volumn 42, Issue 17, 2003, Pages 4055-4067

  Xie, Yi ^a   Hritzko, Benjamin ^a,b   Chin, Chim Yong ^a   Wang, Nien Hwa Linda ^a  

^a PURDUE UNIVERSITY   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SIMULATION; DRUG PRODUCTS; MASS TRANSFER; METHANOL;

RACEMIC MIXTURES;

ESTERS;

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; EMTRICITABINE; ESTER; METHANOL; SOLVENT; SORBENT;

DESIGN; MEDICAL APPLICATION; MOVING BED REGIME; PUMPING SYSTEM; SEPARATION;

ANALYTIC METHOD; ARTICLE; BED; CHIRAL CHROMATOGRAPHY; CHROMATOGRAPHY; COMPUTER SIMULATION; CONTROLLED STUDY; DEAD VOLUME; ENANTIOMER; FLOW RATE; ISOTHERM; LABORATORY; MASS TRANSFER; NONLINEAR SYSTEM; PARAMETER; PERFORMANCE; PRECURSOR; PROCESS DESIGN; PROCESS DEVELOPMENT; PUMP DESIGN; PURIFICATION; RACEMIC MIXTURE; SEPARATION TECHNIQUE; VALIDATION PROCESS;

EID: 0041470235     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie030225t     Document Type: Article

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