High-throughput analysis of plasma fatty acid methyl esters employing robotic transesterification and fast gas chromatography

Lipids

Volumn 43, Issue 2, 2008, Pages 171-180

  Masood, M Athar ^a,c   Salem Jr , Norman ^a,b  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b MSC 9410 ^*  (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Essential fatty acids; Fast gas chromatographic; High throughput gas chromatography; High throughput sample preparation; Plasma fatty acid methyl esters; Robotic transesterification

Indexed keywords

ESSENTIAL FATTY ACID; FATTY ACID ESTER; REAGENT;

ARTICLE; CARDIOVASCULAR RISK; CHRONIC DISEASE; ELUTION; FATTY ACID ANALYSIS; GAS CHROMATOGRAPHY; HEATING; HIGH THROUGHPUT SCREENING; HUMAN; LIPID ANALYSIS; LIPID COMPOSITION; ROBOTICS; TRANSESTERIFICATION;

CHROMATOGRAPHY, GAS; ESTERIFICATION; ESTERS; FATTY ACIDS; REPRODUCIBILITY OF RESULTS; ROBOTICS;

EID: 42549150784     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-007-3130-9     Document Type: Article

References (41)

1. Grossfield A, Feller SE, Pitman MC (2006) Contribution of omega-3 fatty acids to the thermodynamics of membrane protein solvation. J Phys Chem B Condens Matter Mater Surf Interfaces Biophys 110:8907-8909
2. Eldho NV, Feller SE, Nagle ST, Polozov IV, Gawrisch K (2003) Polyunsaturated docosahexaenoic vs docosapentaenoic acid-differences in lipid matrix properties from the loss of one double bond. J Am Chem Soc 125:6409-6421
3. Harris JL, Hibbeln JR, Mackey RH, Muldoon MF (2003) Statin treatment alters fatty acid composition in hypercholesterolemic patients. Circulation 107:119
4. Salem N Jr, Hullin F, Yoffe AM, Karanian JW, Kim HY (1989) Fatty acid and phospholipid species composition of rat tissues after a fish oil diet. Adv Prostaglandin Thromboxane Leukot Res 19:618-622
5. Salem N Jr (1989) Omega-3 fatty acids: molecular and biochemical aspects. In: Spiller G, Scala J (eds) New protective roles of selective nutrients in human nutrition. Liss AR, New York, pp 263-317
6. Makrides M, Neumann MA, Simmer K, Pater J, Gibson RA (2000) A critical appraisal of the role of dietary long chain polyunsaturated fatty acids on neural indices of term infants: a randomized, controlled trail. Pediatrics 105:32-38
7. Weisenger HS, Armitage JA, Sinclair AJ, Vingrys AJ, Burns P, Weisinger RS (2001) Perinatal omega-3 fatty acid deficiency affects blood pressure later in life. Nat Med 7:258-259
8. Neuringer M, Connor WE, Lin DS, Barstad L, Luck S (1986) Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys. Proc Natl Acad Sci 83:4021-4025
9. Bourre JM, Francois M, Youyou A, Dumont O, Piciotti M, Pascal G, Durand G (1989) The effects of dietary alpha-linolenic acid on the composition of nerve membranes, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. J Nutr 119:1880-1892
10. Yamamoto N, Saitoh M, Moriuchi A, Nomura M, Okuyama H (1987) Effects of dietary alpha-linolenate/linoleate balance on brain lipid compositions and learning ability of rats. J Lipid Res 28:144-151
11. Moriguchi T, Salem N Jr (2003) Recovery of brain docosahexaenoate leads to recovery of spatial task performance. J Neurochem 87:297-309
12. Carlson SE, Werkman SH, Peeples JM, Wilson WM (1994) Growth and development of premature infants in relation to omega 3 and omega 6 fatty acid status. World Rev Nutr Diet 75:63-69
13. Willats P, Forsyth JS, DiModugno MK, Varma S, Colvin M (1998) Effects of long-chain polyunsaturated fatty acids in infant formula on problem solving at 10 months of age. Lancet 352:688-691
14. Birch EE, Garfield S, Hoffman DR, Uauy R, Birch DG (2000) A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development of in term infants. Dev Med Child Neurol 42:174-181
15. Contreras MA, Greiner RS, Chang MC, Myers CS, Salem N Jr, Rapoport SI (2000) Nutritional deprivation of alpha-linolenic acid decreases but does not abolish turnover and availability of unacylated docosahexaenoic acid and docosahexaenoyl-CoA in rat brain. J Neurochem 75:2392-2400
16. Su HM, Bernardo L, Mirmiran M, Hong MX, Thomas CN, Nathanielsz PW, Thomas BR (1999) Bioequivalence of dietary alpha-linolenic and docosahexaenoic acids as sources of docosahexanenoate accretion in brain and associated organs of neonatal baboons. Pediatr Res 45:87-93
17. Lefkowitz W, Lim SY, Lin Y, Salem N Jr (2005) Where does the developing brain obtain its docosahexaenoic acid? Relative contribution of dietary [alpha]-linolenic acid, docosahexaenoic acid, and body stores in the developing rat. Pediatr Res 57:157-165
18. Pawlosky RJ, Hibbeln JR, Lin Y, Goodson S, Riggs P, Sebring N, Brown GL, Salem N Jr (2003) Effects of beef- and fish-based diets of the kinetics of n-3 fatty acid metabolism in human subjects. Am J Clin Nutr 77:565-572
19. Lin YH, Pawlosky RJ, Salem N Jr (2005) Simultaneous quantitative determination of deuterium- and carbon-13-labeled essential fatty acids in rat plasma. J Lipid Res 46:1974-1982
20. Simopoulos AP (2004) The traditional diet of Greece and cancer. Eur J Cancer Prev 13:219-230
21. Harris WE (2007) Omega-3 fatty acids and cardiovascular disease: a case for omega-3 index as a new risk factor. Pharmacol Res 55:217-223
22. Lands WEM (1995) Long-term fat intake and biomarkers. Am J Clin Nutr 61:721S-725S
23. von Schacky C (2007) Omega-3 fatty acids and cardiovascular disease. Curr Opin Clin Nutr Metab Care 10:129-135
24. Lands WEM, Libelt B, Morris A, Kramer NC, Prewitt TE, Bowen P, Schmeisser D, Davidson M, Burns JH (1992) Maintenance of lower proportions of (n-6) eicosanoid precursors in phospholipids of human plasma in response to added dietary (n-3) fatty acids. Biochim Biophys Acta 1180:147-162
25. Lands WEM (1993) Eicosanoids and health. Ann N Y Acad Sci 676:40-59
26. Albert CM, Campos H, Stampfer MJ, Ridker PM, Manson JE, Willett WC, Ma J (2002) Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med 346:1113-1118
27. Lemaitre RN, King IB, Mozaffarian D, Kuller LH, Tracy RP, Siscovick DS (2003) n-3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the cardiovascular health study. Am J Clin Nutr 77:319-325
28. Simon JA, Hodgkins ML, Browner WS, Neuhaus JM, Bernert JT Jr, Hulley SB (1995) Serum fatty acids and the risk of coronary heart disease. Am J Epidemiol 142:469-476
29. Kang JX, Leaf A (1996) The cardiac antiarrhythmic affects of polyunsaturated fatty acids. Lipids 31:S41-S44
30. Marchiolli R, Barzi F, Bomba E, Chieffo C, Di Gregorio D, Di Mascio R, Franzosi MG, Geraci E, Levantesi G, Maggioni AP, Mantini L, Marfisi RM, Mastrogiuseppe G, Mininni N, Nicolosi GL, Santini M, Schweiger C, Tavazzi L, Tognoni G, Tucci C, Valagussa F (2002) Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time course analysis of the results of the gruppo italiano per lo studio della sopravvivenza nell'infarto miocardico (GISSI)-Prevenzione. Circulation 105:1897-1903
31. Mihrshahi S, Peat JK, Webb K, Tovey ER, Marks GB, Mellis CM, Leeder SR (2001) The childhood asthma prevention study (CAPS): design and research protocol of a randomized trial for the primary prevention of asthma. Control Clin Trials 22:333-354
32. Coleman H, Chew E, AREDS2 (2007) Nutritional supplementation in age-related macular degeneration. Curr Opin Ophthalmol 3:220-223
33. Smithers LG, McPhee AJ, Gibson RA, Makrides M (2004) Visual development of preterm infants fed high dose docosahexaenoic acid. Asia Pac J Clin Nutr 13:S50
34. New Alzheimer's clinical trials to be undertaken by NIA nationwide consortium. http://www.nia.nih.gov/Alzheimers/ResearchInformation/NewsReleases/ PR20061017ADC
35. Masood MA, Stark KD, Salem N Jr (2005) A simplified and efficient method for the analysis of fatty acid methyl esters suitable for large clinical studies. J Lipid Res 46:2299-2305
36. Lepage G, Roy CC (1986) Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res 27:114-120
37. Stark KD, Salem N Jr (2005) Fast gas chromatography methods and column selection for the identification of fatty acid methyl esters from mammalian samples. Lipid Technol 17:181-185
38. Thermo Application Note 10058, http://www.thermo.com/com/cda/products/ product_application_details/1,12075,00.html
39. Kuksis A (2007) Lipidomics in triacylglycerol and cholesteryl and cholesterol ester oxidation. Front Biosci 12:3203-3246
40. Merrill AH Jr, Sullards MC, Allegood JC, Kelly S, Wang E (2005) Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry. Methods 36:207-224
41. Han X, Gross RW (2005) Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples. Mass Spectrom Rev 24:367-412