Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling

Proteomics

Volumn 8, Issue 8, 2008, Pages 1586-1594

  Löbke, Christian ^a   Laible, Mark ^a   Rappl, Claudia ^a   Ruschhaupt, Markus ^a   Sahin, Özgür ^a   Arlt, Dorit ^a   Wiemann, Stefan ^a   Poustka, Annemarie ^a   Sültmann, Holger ^a   Korf, Ulrike ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

EGFR; Gefitinib; HER2 neu; Herceptin; Reverse phase protein array

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; GEFITINIB; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEU DIFFERENTIATION FACTOR; PROTEIN KINASE; TRASTUZUMAB;

AMINO ACID SEQUENCE; ANTIBODY LABELING; ARTICLE; BREAST CANCER; CELL STIMULATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN MICROARRAY; PROTEIN PHOSPHORYLATION; PROTEOMICS; SIGNAL TRANSDUCTION;

ANTIBODIES, MONOCLONAL; BREAST NEOPLASMS; EPIDERMAL GROWTH FACTOR; GLUTATHIONE TRANSFERASE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROTEIN ARRAY ANALYSIS; PROTO-ONCOGENE PROTEINS C-AKT; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS; REFERENCE STANDARDS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 42549122118     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200700733     Document Type: Article

References (26)

1. Charboneau, L., Scott, H., Chen, T., Winters, M. et al., Utility of reverse phase protein arrays: Applications to signaling pathways and human body arrays. Brief. Funct. Genomic Proteomic 2002, 3, 305-315.
2. Loebke, C., Sueltmann, H., Schmidt, C., Henjes, F. et al., Infrared-based protein detection arrays for quantitative proteomics. Proteomics 2007, 7, 558-64.
3. Sahin, Ö., Löbke, C., Korf, U., Appelhans, H. et al., Combinatorial RNAi for quantitative protein network analysis. PNAS 2007, 16, 6579-6584.
4. Delehanty, L. B., Printing functional protein microarrays using piezoelectric capillaries. Methods Mol. Biol. 2004, 264, 135-143.
5. Stears, R. L., Martinsky, T., Schena, M., Trends in microarray analysis. Nat. Med. 2003, 1, 140-145.
6. Shalon, D., Smith, S. J., Brown, P. O., A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. Genome Methods 1996, 639-645.
7. Hall, D., Producing protein microarrays for drug discovery. DrugPlus Int. 2006, 11.
8. Pabst, M. J., Habig, W. H., Jakoby, W. B., Glutathione S-transferase A. A novel kinetic mechanism in which the major reaction pathway depends on substrate concentration. J. Biol. Chem. 1974, 249, 7140-7150.
9. Calvert, V. S., Tang, Y., Boveia, V., Wulfkuhle, J. et al., Development of multiplexed protein profiling and detection using near infrared detection of reverse-phase protein microarrays. Clin. Proteomics J. 2004, 1, 81-89.
10. Osborne, C. K., Hamilton, B., Titus, G. Livingston, R. B., Epidermal growth factor stimulation of human breast cancer cells in culture. Cancer Res. 1980, 40, 2361-2366.
11. Tan, M., Grijalva, R., Yu, D., Heregulin β1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase. Cancer Res. 1999, 59, 1620-1625.
12. Gregory, C. W., Whang, Y. E., McCall, W., Fei, X. et al., Heregulin-induced activation of HER2 and HER3 increases adrogen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth. Clin. Cancer Res. 2005, 11, 1704-1712.
13. Holbro, T., Civenni, G., Hynes, N. E., The ERBB receptors and their role in cancer progression. Exp. Cell Res. 2002, 284, 99-110.
14. Schulze, W. X., Deng, L., Mann, M., Phosphotyrosine interactome of the ERBB receptor kinase family. Mol. Syst. Biol. 2005, 1, 1744-4292.
15. Riese, D. J., Stern, D. F., Specificity within the EGF family/ ERBB receptor family signaling network. BioEssays 1998, 20, 41-48.
16. Han, S. W., Hwang, P. G., Chung, D. H., Kim, D. W. et al., Epidermal growth factor receptor (EGFR) downstream molecules as response predictive markers for gefitinib (Iressa®, ZD1839) in chemotherapy-resistant nonsmall cell lung cancer. Int. J. Cancer 2005, 113, 109-115.
17. Nahta, R., Hung, M. C., Esteva, F. J., The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res. 2004, 64, 2343-2346.
18. Yarden, Y., Biology of HER2 and its importance in breast cancer. Oncology 2001, 61, 1-13.
19. Korf, U., Kohl, T., van der Zandt, H., Zahn, R. et al., Large-scale protein expression for proteome research.Proteomics 2005, 14, 3571-3580.
20. Schutz-Geschwender, A., Zhang, Y., Holt, T., McDermitt, D. et al., Quantitative, two-color Western blot detection with infrared fluorescence. LI-COR, Biosciences, 2004, http:// www.licor.com/bio/ QuantitativeWesterns/index.jsp.
21. Martin, M. B., Franke, T. F., Stoica, G. E., Chambon, P. et al., A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I. Endocrinology 2007, 141, 4503-4511.
22. Xing, C., Imagawa, W., Altered MAP kinase (ERK1/2) regulation in primary cultures of mammary tumor cells: Elevated basal activity and sustained response to EGF. Carcinogenesis 1999, 20, 1201-1208.
23. Sweeney, C., Fambrough, D., Huard, C., Diamonti, A. J. et al., Growth factor-specific signaling pathway stimulation and gene expression mediated by ErbB receptors. J. Biol. Chem. 2001, 276, 22685-22698.
24. Pierce, K. L., Luttrell, L. M., Lefkowitz, R. J., New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades. Oncogene 2001, 20, 1532-1539.
25. Guy, P. M., Platko, J. V., Cantley, L. C., Cerione, R. A. et al., Insect cell-expressed p180ERBB3 possesses an impaired tyrosine kinase activity. Proc. PNAS 1994, 91, 8132-8136.
26. Wolf-Yadlin, A., Kumar, N., Zhang, Y., Hautaniemi, S. et al., Effects of HER2 overexpression on cell signaling networks governing proliferation and migration. Mol. Syst. Biol. 2006, 2, 54.