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Volumn 20, Issue 7, 1999, Pages 1201-1208

Altered MAP kinase (ERK1,2) regulation in primary cultures of mammary tumor cells: Elevated basal activity and sustained response to EGF

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGENIC AGENT; PROTEIN KINASE INHIBITOR;

EID: 0032804226     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.7.1201     Document Type: Article
Times cited : (49)

References (48)
  • 1
    • 0028884216 scopus 로고
    • Growth factors in breast cancer
    • Dickson, R. and Lippman, M. (1995) Growth factors in breast cancer. Endocrine Rev., 16, 559-589.
    • (1995) Endocrine Rev. , vol.16 , pp. 559-589
    • Dickson, R.1    Lippman, M.2
  • 2
    • 0027515046 scopus 로고
    • Epidermal growth factor receptor levels increase but epidermal growh factor receptor ligand levels decrease in mouse mammary tumors during progression from hormone dependence to hormone independence
    • Kienhuis, C., Sluyser, M., de Goeij, C., Koenders, P. and Benraad, T. (1993) Epidermal growth factor receptor levels increase but epidermal growh factor receptor ligand levels decrease in mouse mammary tumors during progression from hormone dependence to hormone independence. Breast Cancer Res. Treat., 26, 289-295.
    • (1993) Breast Cancer Res. Treat. , vol.26 , pp. 289-295
    • Kienhuis, C.1    Sluyser, M.2    De Goeij, C.3    Koenders, P.4    Benraad, T.5
  • 3
    • 0026786658 scopus 로고
    • Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells
    • van Agthoven, T., van Agthoven, T.L.A., Portengen, H., Foekens, J. and Dorssers, L. (1993) Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells. Cancer Res., 52, 5082-5088.
    • (1993) Cancer Res. , vol.52 , pp. 5082-5088
    • Van Agthoven, T.1    Van Agthoven, T.L.A.2    Portengen, H.3    Foekens, J.4    Dorssers, L.5
  • 4
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger, J. and Ullrich, A. (1992) Growth factor signaling by receptor tyrosine kinases. Neuron, 9, 383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 6
    • 0028000009 scopus 로고
    • Activation of the ras signalling pathway in human breast cancer cells overexpressing erbB-2
    • Janes, P., Daly, R., deFazio, A. and Sutherland, R. (1994) Activation of the ras signalling pathway in human breast cancer cells overexpressing erbB-2. Oncogene, 9, 3601-3608.
    • (1994) Oncogene , vol.9 , pp. 3601-3608
    • Janes, P.1    Daly, R.2    DeFazio, A.3    Sutherland, R.4
  • 7
    • 0028079956 scopus 로고
    • Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts
    • Brunet, A., Pages, G. and Pouyssegur, J. (1994) Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts. Oncogene, 9, 3379-3387.
    • (1994) Oncogene , vol.9 , pp. 3379-3387
    • Brunet, A.1    Pages, G.2    Pouyssegur, J.3
  • 10
    • 0030946366 scopus 로고    scopus 로고
    • Hyperexpression of mitogen-activated protein kinase in human breast cancer
    • Sivaraman, V., Wang, H.-y., Nuovo, G. and Malbon, C. (1997) Hyperexpression of mitogen-activated protein kinase in human breast cancer. J. Clin. Invest., 99, 1478-1483.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1478-1483
    • Sivaraman, V.1    Wang, H.-Y.2    Nuovo, G.3    Malbon, C.4
  • 12
    • 0011286643 scopus 로고
    • Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer
    • Price, J., Turner, D. and Cepko, C. (1987) Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer. Proc. Natl Acad. Sci. USA, 84, 156-160.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 156-160
    • Price, J.1    Turner, D.2    Cepko, C.3
  • 13
    • 0026464751 scopus 로고
    • Pregnancy-dependent to ovarian-independent progression in mammary tumors delineated in primary culture: Changes in signal transduction, growth factor regulation and matrix interaction
    • Imagawa, W., Bandyopadhyay, G., Garcia, M., Matsuzawa, A. and Nandi, S. (1992) Pregnancy-dependent to ovarian-independent progression in mammary tumors delineated in primary culture: Changes in signal transduction, growth factor regulation and matrix interaction. Cancer Res., 52, 6531-6538.
    • (1992) Cancer Res. , vol.52 , pp. 6531-6538
    • Imagawa, W.1    Bandyopadhyay, G.2    Garcia, M.3    Matsuzawa, A.4    Nandi, S.5
  • 14
    • 0023845957 scopus 로고
    • Morphogenesis of mammary epithelial cells from virgin mice growing within collagen gels: Ultrastructural and immunocytochemical characterization
    • Hamamoto, S., Imagawa, W., Yang, J. and Nandi, S. (1987) Morphogenesis of mammary epithelial cells from virgin mice growing within collagen gels: Ultrastructural and immunocytochemical characterization. Cell Differ., 22, 191-202.
    • (1987) Cell Differ. , vol.22 , pp. 191-202
    • Hamamoto, S.1    Imagawa, W.2    Yang, J.3    Nandi, S.4
  • 15
    • 0025057376 scopus 로고
    • Casein accumulation in mouse mammary epithelial cells after growth stimulated by different hormonal and nonhormonal agents
    • Levay-Young, B.K., Hamamoto, S., Imagawa, W. and Nandi, S. (1990) Casein accumulation in mouse mammary epithelial cells after growth stimulated by different hormonal and nonhormonal agents. Endocrinology, 126, 1173-1182.
    • (1990) Endocrinology , vol.126 , pp. 1173-1182
    • Levay-Young, B.K.1    Hamamoto, S.2    Imagawa, W.3    Nandi, S.4
  • 16
    • 0342541584 scopus 로고
    • An improved fluorimetric assay for DNA
    • Hinegardner, R. (1971) An improved fluorimetric assay for DNA. Anal. Biochem., 41, 477-487.
    • (1971) Anal. Biochem. , vol.41 , pp. 477-487
    • Hinegardner, R.1
  • 17
    • 0029147851 scopus 로고
    • Immune complex kinase assays for mitogen-activated protein kinase and MEK
    • Reuter, C., Catling, A. and Weber, M. (1995) Immune complex kinase assays for mitogen-activated protein kinase and MEK. Methods Enzymol., 255, 245-279.
    • (1995) Methods Enzymol. , vol.255 , pp. 245-279
    • Reuter, C.1    Catling, A.2    Weber, M.3
  • 18
    • 0022981163 scopus 로고
    • SomatomedinC substitutes for insulin for the growth of mammary epithelial cells from normal virgin mice in serum-free collagen gel cell culture
    • Imagawa, W., Spencer, E.M., Larson, L. and Nandi, S. (1986) SomatomedinC substitutes for insulin for the growth of mammary epithelial cells from normal virgin mice in serum-free collagen gel cell culture. Endocrinology, 119, 2695-2699.
    • (1986) Endocrinology , vol.119 , pp. 2695-2699
    • Imagawa, W.1    Spencer, E.M.2    Larson, L.3    Nandi, S.4
  • 19
    • 0029030120 scopus 로고
    • Multifunctional phosphatidic acid signaling in mammary epithelial cells: Stimulation of phosphoinositide hydrolysis and conversion to diglyceride
    • Imagawa, W., Bandyopadhyay, G. and Nandi, S. (1995) Multifunctional phosphatidic acid signaling in mammary epithelial cells: Stimulation of phosphoinositide hydrolysis and conversion to diglyceride. J. Cell Physiol., 163, 561-569.
    • (1995) J. Cell Physiol. , vol.163 , pp. 561-569
    • Imagawa, W.1    Bandyopadhyay, G.2    Nandi, S.3
  • 20
  • 21
    • 0027306121 scopus 로고
    • The human CL100 gene encodes a tyr/thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in xenopus oocyte extracts
    • Alessi, D., Smythe, C. and Keyse, S. (1993) The human CL100 gene encodes a tyr/thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in xenopus oocyte extracts. Oncogene, 8, 2015-2020.
    • (1993) Oncogene , vol.8 , pp. 2015-2020
    • Alessi, D.1    Smythe, C.2    Keyse, S.3
  • 23
    • 0029818289 scopus 로고    scopus 로고
    • Kinetic and biochemical correlation between sustained p44 ERK 1 (44 kDa extracellular signal-regulated kinase) activation and lysophosphatidic acid-stimulated DNA synthesis in Rat-1 cells
    • Cook, S. and McCormick, F. (1996) Kinetic and biochemical correlation between sustained p44 ERK 1 (44 kDa extracellular signal-regulated kinase) activation and lysophosphatidic acid-stimulated DNA synthesis in Rat-1 cells. Biochem. J., 320, 237-245.
    • (1996) Biochem. J. , vol.320 , pp. 237-245
    • Cook, S.1    McCormick, F.2
  • 25
    • 0026720523 scopus 로고
    • mapk (ERK1) by growth factors: Correlation between late phase activation and mitogenicity
    • mapk (ERK1) by growth factors: Correlation between late phase activation and mitogenicity. Mot. Endocrinol., 6, 845-854.
    • (1992) Mot. Endocrinol. , vol.6 , pp. 845-854
    • Meloche, S.1    Seuwen, K.2    Pagès, G.3    Pouysségur, J.4
  • 26
    • 0020771662 scopus 로고
    • Comparison of the growth of normal and neoplastic mouse mammary cells on plastic, on collagen gels and in collagen gels
    • Richards, J., Pasco, D., Yang, J., Guzman, R. and Nandi, S. (1983) Comparison of the growth of normal and neoplastic mouse mammary cells on plastic, on collagen gels and in collagen gels. Exp. Cell Res., 146, 1-14.
    • (1983) Exp. Cell Res. , vol.146 , pp. 1-14
    • Richards, J.1    Pasco, D.2    Yang, J.3    Guzman, R.4    Nandi, S.5
  • 27
    • 0028216315 scopus 로고
    • MAP kinases ERK1 and ERK2: Pleiotropic enzymes in a ubiquitous signaling network
    • Robbins, D., Zhen, E., Cheng, M., Xu, S., Ebert, D. and Cobb, M. (1994) MAP kinases ERK1 and ERK2: pleiotropic enzymes in a ubiquitous signaling network. Adv. Cancer Res., 63, 93-117.
    • (1994) Adv. Cancer Res. , vol.63 , pp. 93-117
    • Robbins, D.1    Zhen, E.2    Cheng, M.3    Xu, S.4    Ebert, D.5    Cobb, M.6
  • 28
    • 0027283659 scopus 로고
    • Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts
    • Lenormand, P., Sardet, C., Pages, G., L'Allemain, G., Brunet, A. and Pouyssegur, J. (1993) Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts. J. Cell Biol., 122, 1079-1088.
    • (1993) J. Cell Biol. , vol.122 , pp. 1079-1088
    • Lenormand, P.1    Sardet, C.2    Pages, G.3    L'Allemain, G.4    Brunet, A.5    Pouyssegur, J.6
  • 29
    • 0028483678 scopus 로고
    • EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor
    • Traverse, S., Seedorf, K., Paterson, H., Marshall, C., Cohen, P. and Ullrich, A. (1994) EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Curr. Biol., 4, 694-701.
    • (1994) Curr. Biol. , vol.4 , pp. 694-701
    • Traverse, S.1    Seedorf, K.2    Paterson, H.3    Marshall, C.4    Cohen, P.5    Ullrich, A.6
  • 30
    • 0029669930 scopus 로고    scopus 로고
    • Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells
    • Migliaccio, A., Di-Domenico, M., Castoria, G., de-Falco, A., Bontempo, P., Nola, E. and Auricchio, F. (1996) Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells. EMBO J., 15, 1292-1300.
    • (1996) EMBO J. , vol.15 , pp. 1292-1300
    • Migliaccio, A.1    Di-Domenico, M.2    Castoria, G.3    De-Falco, A.4    Bontempo, P.5    Nola, E.6    Auricchio, F.7
  • 31
    • 0030642041 scopus 로고    scopus 로고
    • Estrogen receptor, growth factor receptor and protooncogene protein activities and possible signal transduction crosstalk in estrogen dependent and independent breast cancer cell lines
    • Mohamood, A., Gyles, P., Balan, G., Holis, V., Eckberg, E., Asseffa, A., Han, Z., Wyche, J. and Anderson, W. (1997) Estrogen receptor, growth factor receptor and protooncogene protein activities and possible signal transduction crosstalk in estrogen dependent and independent breast cancer cell lines. J. Submicrosc. Cytol. Pathol., 29, 1-17.
    • (1997) J. Submicrosc. Cytol. Pathol. , vol.29 , pp. 1-17
    • Mohamood, A.1    Gyles, P.2    Balan, G.3    Holis, V.4    Eckberg, E.5    Asseffa, A.6    Han, Z.7    Wyche, J.8    Anderson, W.9
  • 33
    • 0032530222 scopus 로고    scopus 로고
    • Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells
    • Coutts, A. and Murphy, L. (1998) Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells. Cancer Res., 58, 4071-4074.
    • (1998) Cancer Res. , vol.58 , pp. 4071-4074
    • Coutts, A.1    Murphy, L.2
  • 34
    • 14444288522 scopus 로고    scopus 로고
    • The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
    • Huang, H., Nagane, M., Klingbeil, C., Lin, H., Nishikawa, R., Ji, X., Huang, C., Gill, G., Wiley, H. and Cavenee, W. (1997) The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J. Biol. Chem., 272, 2927-2935.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2927-2935
    • Huang, H.1    Nagane, M.2    Klingbeil, C.3    Lin, H.4    Nishikawa, R.5    Ji, X.6    Huang, C.7    Gill, G.8    Wiley, H.9    Cavenee, W.10
  • 35
    • 0027430339 scopus 로고
    • Mitogen-activated protein kinase regulates the epidermal growth factor receptor through activation of a tyrosine phosphatase
    • Griswold-Prenner, I., Carlin, C. and Rosner, M. (1993) Mitogen-activated protein kinase regulates the epidermal growth factor receptor through activation of a tyrosine phosphatase. J. Biol. Chem., 268, 13050-13054.
    • (1993) J. Biol. Chem. , vol.268 , pp. 13050-13054
    • Griswold-Prenner, I.1    Carlin, C.2    Rosner, M.3
  • 36
    • 16944367130 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C
    • Morrison, P., Saltiel, A. and Rosner, M. (1996) Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C. J. Biol. Chem., 271, 12891-12896.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12891-12896
    • Morrison, P.1    Saltiel, A.2    Rosner, M.3
  • 37
    • 0030852873 scopus 로고    scopus 로고
    • The linoleic acid metabolite, (13S)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation
    • Glasgow, W., Hui, R., Everhart, A., Jayawickreme, S.P., Angerman-Sterwart, J., Han, B.-B. and Eling, T. (1997) The linoleic acid metabolite, (13S)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. J. Biol. Chem., 272, 19269-19276.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19269-19276
    • Glasgow, W.1    Hui, R.2    Everhart, A.3    Jayawickreme, S.P.4    Angerman-Sterwart, J.5    Han, B.-B.6    Eling, T.7
  • 38
    • 0029151931 scopus 로고
    • Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells
    • Tomic, S., Greiser, U., Lammers, R., Kharitonenkov, A., Imyanitov, E., Ullrich, A. and Bohmer, F.-D. (1995) Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. J. Biol. Chem., 270, 21277-21284.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21277-21284
    • Tomic, S.1    Greiser, U.2    Lammers, R.3    Kharitonenkov, A.4    Imyanitov, E.5    Ullrich, A.6    Bohmer, F.-D.7
  • 39
    • 0031943946 scopus 로고    scopus 로고
    • Effects of protein tyrosine phosphatase inhibitors on EGF-and insulin-dependent mammary epithelial cell growth
    • McIntyre, B., Briski, K., Hosick, H. and Sylvester, P. (1998) Effects of protein tyrosine phosphatase inhibitors on EGF-and insulin-dependent mammary epithelial cell growth. Proc. Soc. Exp. Biol. Med., 217, 180-187.
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.217 , pp. 180-187
    • McIntyre, B.1    Briski, K.2    Hosick, H.3    Sylvester, P.4
  • 40
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark, E. and Brugge, J. (1995) Integrins and signal transduction pathways: the road taken. Science, 268, 233-239.
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.1    Brugge, J.2
  • 42
    • 0030453194 scopus 로고    scopus 로고
    • Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors
    • Miyamoto, S., Teramoto, H., Gutkind, S. and Yamada, K. (1996) Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. J. Cell Biol., 135, 1633-1642.
    • (1996) J. Cell Biol. , vol.135 , pp. 1633-1642
    • Miyamoto, S.1    Teramoto, H.2    Gutkind, S.3    Yamada, K.4
  • 43
    • 0031003237 scopus 로고    scopus 로고
    • Cell anchorage permits efficient signal transduction between ras and its downstream kinases
    • Lin, T., Chen, Q., Howe, A. and Juliano, R. (1997) Cell anchorage permits efficient signal transduction between ras and its downstream kinases. J. Biol. Chem., 272, 8849-8852.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8849-8852
    • Lin, T.1    Chen, Q.2    Howe, A.3    Juliano, R.4
  • 44
    • 0019777834 scopus 로고
    • Type I collagen reduces the degradation of basal lamina proteoglycan by mammary epithelial cells
    • David, G. and Bernfield, M. (1981) Type I collagen reduces the degradation of basal lamina proteoglycan by mammary epithelial cells. J. Cell Biol., 91, 281-286.
    • (1981) J. Cell Biol. , vol.91 , pp. 281-286
    • David, G.1    Bernfield, M.2
  • 45
    • 0019510753 scopus 로고
    • Differential response to growth factor by rat mammary epithelium plated on different collagen substrata in serum-free medium
    • Salomon, D.S., Liotta, L.A. and Kidwell, W.R. (1981) Differential response to growth factor by rat mammary epithelium plated on different collagen substrata in serum-free medium. Proc. Natl Acad. Sci. USA, 78, 382-386.
    • (1981) Proc. Natl Acad. Sci. USA , vol.78 , pp. 382-386
    • Salomon, D.S.1    Liotta, L.A.2    Kidwell, W.R.3
  • 46
    • 0030056588 scopus 로고    scopus 로고
    • Ligand activation of overexpressed epidermal growth factor receptor results in loss of epithelial phenotype and impaired RGD-sensitive integrin function in HSC-1 cells
    • Fujii, K. (1996) Ligand activation of overexpressed epidermal growth factor receptor results in loss of epithelial phenotype and impaired RGD-sensitive integrin function in HSC-1 cells. J. Invest. Dermatol., 107, 195-202.
    • (1996) J. Invest. Dermatol. , vol.107 , pp. 195-202
    • Fujii, K.1
  • 47
    • 0030297552 scopus 로고    scopus 로고
    • From form to function: Signaling by protein tyrosine phosphatases
    • Tonks, N. and Neel, B. (1996) From form to function: Signaling by protein tyrosine phosphatases. Cell, 87, 365-368.
    • (1996) Cell , vol.87 , pp. 365-368
    • Tonks, N.1    Neel, B.2
  • 48
    • 0029905354 scopus 로고    scopus 로고
    • Differential regulation of the MAP, SAP and RK/p38 kinases by pystl, a novel cytosolic dual-specificity phosphatase
    • Groom, L., Sneddon, A., Alessi, D., Dowd, S. and Keyse, S. (1996) Differential regulation of the MAP, SAP and RK/p38 kinases by Pystl, a novel cytosolic dual-specificity phosphatase. EMBO J., 15, 3621-3632.
    • (1996) EMBO J. , vol.15 , pp. 3621-3632
    • Groom, L.1    Sneddon, A.2    Alessi, D.3    Dowd, S.4    Keyse, S.5


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