Gene expression profiles and intracellular contents of stress protectants in Saccharomyces cerevisiae under ethanol and sorbitol stresses

Applied Microbiology and Biotechnology

Volumn 79, Issue 2, 2008, Pages 273-283

  Kaino, Tomohiro ^a   Takagi, Hiroshi ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Expression; Gene; Glycerol; Proline; Saccharomyces cerevisiae; Stress response; Trehalose

Indexed keywords

PROLINE; STRESS RESPONSE; TREHALOSE;

BIOSYNTHESIS; ETHANOL; FREEZING; GENE EXPRESSION; OSMOSIS; STRESS ANALYSIS;

YEAST;

ALCOHOL; GLYCEROL; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; PHOSPHATASE; PROLINE; SORBITOL; TREHALOSE; TREHALOSE 6 PHOSPHATE PHOSPHATASE; UNCLASSIFIED DRUG;

ENVIRONMENTAL STRESS; ETHANOL; GENE EXPRESSION; YEAST;

AMINO ACID SYNTHESIS; ARTICLE; BACTERIAL GENE; CELL PROTECTION; CHEMICAL STRESS; DEGRADATION; ENZYME ACTIVITY; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE INDUCTION; GPD1 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTECTION; PUT4 GENE; SACCHAROMYCES CEREVISIAE; TPS2 GENE; YEAST CELL;

ETHANOL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; GLYCEROL; GLYCEROLPHOSPHATE DEHYDROGENASE; PHOSPHORIC MONOESTER HYDROLASES; PROLINE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SORBITOL; TREHALOSE;

BACTERIA (MICROORGANISMS); SACCHAROMYCES CEREVISIAE;

EID: 42549086290     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-008-1431-4     Document Type: Article

References (59)

1. Albertyn J, Hohmann S, Prior BA (1994) Characterization of the osmotic-stress response in Saccharomyces cerevisiae: osmotic stress and glucose repression regulate glycerol-3-phosphate dehydrogenase independently. Curr Genet 25:12-18
2. Alexandre H, Ansanay-Galeote V, Dequin S, Blondin B (2001) Global gene expression during short-term ethanol stress in Saccharomyces cerevisiae. FEBS Lett 498:98-103
3. Alizadeh P, Klionsky DJ (1996) Purification and biochemical characterization of the ATH1 gene product, vacuolar acid trehalase, from Saccharomyces cerevisiae. FEBS Lett 391:273-278
4. Ando A, Nakamura T, Murata Y, Takagi H, Shima J (2007) Identification and classification of genes required for tolerance to freeze-thaw stress revealed by genome-wide screening of Saccharomyces cerevisiae deletion strains. FEMS Yeast Res 7:244-253
5. André L, Hemming A, Adler L (1991) Osmoregulation in Saccharomyces cerevisiae. Studies on the osmotic induction of glycerol production and glycerol 3-phosphate dehydrogenase (NAD+). FEBS Lett 286:13-17
6. Aravind L, Koonin EV (1999) Novel predicted RNA-binding domains associated with the translation machinery. J Mol Evol 48:291-302
7. Attfield PV (1987) Trehalose accumulates in Saccharomyces cerevisiae during exposure to agents that induce heat shock response. FEBS Lett 225:259-263
8. Bell W, Sun W, Hohmann S, Wera S, Reinders A, De Virgilio C, Wiemken A, Thevelein JM (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273:33311-33319
9. +) in acquired osmotolerance of Saccharomyces cerevisiae. J Bacteriol 171:1087-1092
10. Brandriss MC (1983) Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT2 gene. Mol Cell Biol 3:1846-1856
11. 1- pyrroline-5-carboxylate reductase. J Bacteriol 174:3782-3788
12. Causton HC, Ren B, Koh SS, Harbison CT, Kanin E, Jennings EG, Lee TI, True HL, Lander ES, Young RA (2001) Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell 12:323-337
13. Chen C, Dickman MB (2005) Proline suppresses apoptosis in the fungal pathogen Colletotrichum trifolii. Proc Natl Acad Sci U S A 102:3459-3464
14. Degols G, Jauniaux JC, Wiame JM (1987) Molecular characterization of transposable-element-associated mutations that lead to constitutive l-ornithine aminotransferase expression in Saccharomyces cerevisiae. Eur J Biochem 165:289-296
15. Delauney AJ, Verma DPS (1993) Proline biosynthesis and osmoregulation in plants. Plant J 4:215-223
16. Garay-Arroyo A, Lledías F, Hansberg W, Covarrubias AA (2003) Cu,Zn-superoxide dismutase of Saccharomyces cerevisiae is required for resistance to hyperosmosis. FEBS Lett 539:68-72
17. Gent DP, Slaughter JC (1998) Intracellular distribution of amino acids in an slp1 vacuole-deficient mutant of the yeast Saccharomyces cerevisiae. J Appl Microbiol 84:752-758
18. Hallsworth JE (1998) Ethanol-induced water stress in yeast. J Ferment Bioeng 85:125-137
19. Hallsworth JE, Heim S, Timmis KN (2003a) Chaotropic solutes cause water stress in Pseudomonas putida. Environ Microbiol 5:1270-1280
20. Hallsworth JE, Prior BA, Nomura Y, Iwahara M, Timmis KN (2003b) Compatible solutes protect against chaotrope (ethanol)-induced, nonosmotic water stress. Appl Environ Microbiol 69:7032-7034
21. 1-pyrroline-5-carboxylate synthetase results in increased proline accumulation and protection of plants from osmotic stress. Plant Physiol 122:1129-1136
22. Kandror O, Bretschneider N, Kreydin E, Cavalieri D, Goldberg AL (2004) Yeast adapt to near-freezing temperatures by STRE/Msn2,4-dependent induction of trehalose synthesis and certain molecular chaperones. Mol Cell 13:771-781
23. 1-pyrroline-5-carboxylate synthetase increases proline production and confers osmotolerance in transgenic plants. Plant Physiol 108:1387-1394
24. Kopp M, Müller H, Holzer H (1993) Molecular analysis of the neutral trehalase gene from Saccharomyces cerevisiae. J Biol Chem 268:4766-4774
25. Kunkee RE, Bisson LF (1993) Wine-making yeast. In: Rose AH, Harrison JS (eds) The yeast. vol. 5. 2nd edn. Academic, San Diego, California, pp 94-99
26. +) complements an osmosensitive mutant of Saccharomyces cerevisiae. Mol Microbiol 10:1101-1111
27. Lasko PF, Brandriss MC (1981) Proline transport in Saccharomyces cerevisiae. J Bacteriol 148:241-247
28. Liang LK, Wang XK, Zhu KL, Chi ZM (2007) Trehalose synthesis in Saccharomycopsis fibuligera does not respond to stress treatments. Appl Microbiol Biotechnol 74:1084-1091
29. -ΔΔCT method. Methods 25:402-408
30. Mansure JJC, Panek AD, Crowe LM, Crowe JH (1994) Trehalose inhibits ethanol effects on intact yeast cells and liposomes. Biochim Biophys Acta 1191:309-316
31. Martínez-Force E, Benítez T (1995) Effects of varying media, temperature, and growth rates on the intracellular concentrations of yeast amino acids. Biotechnol Prog 11:386-392
32. Matsuura K, Takagi H (2005) Vacuolar functions are involved in stress-protective effect of intracellular proline in Saccharomyces cerevisiae. J Biosci Bioeng 100:538-544
33. Middelhoven WJ (1964) The pathway of arginine breakdown in Saccharomyces cerevisiae. Biochim Biophys Acta 93:650-652
34. Morita Y, Nakamori S, Takagi H (2003) l-proline accumulation and freeze tolerance of Saccharomyces cerevisiae are caused by a mutation in the PRO1 gene encoding γ-glutamyl kinase. Appl Environ Microbiol 69:212-219
35. Morita Y, Nakamori S, Takagi H (2002) Effect of proline and arginine metabolism on freezing stress of Saccharomyces cerevisiae. J Biosci Bioeng 94:390-394
36. Nakashima K, Satoh R, Kiyosue T, Yamaguchi-Shinozaki K, Shinozaki K (1998) A gene encoding proline dehydrogenase is not only induced by proline and hypoosmolarity, but is also developmentally regulated in the reproductive organs of Arabidopsis. Plant Physiol 118:1233-1241
37. Ohsumi Y, Kitamoto K, Anraku Y (1988) Changes induced in the permeability barrier of the yeast plasma membrane by cupric ion. J Bacteriol 170:2676-2682
38. Påhlman AK, Granath K, Ansell R, Hohmann S, Adler L (2001) The yeast glycerol 3-phosphatases Gpp1p and Gpp2p are required for glycerol biosynthesis and differentially involved in the cellular responses to osmotic, anaerobic, and oxidative stress. J Biol Chem 276:3555-3563
39. Panadero J, Pallotti C, Rodríguez-Vargas S, Randez-Gil F, Prieto JA (2006) A downshift in temperature activates the high osmolarity glycerol (HOG) pathway, which determines freeze tolerance in Saccharomyces cerevisiae. J Biol Chem 281:4638-4645
40. Pavlik P, Simon M, Schuster T, Ruis H (1993) The glycerol kinase (GUT1) gene of Saccharomyces cerevisiae: cloning and characterization. Curr Genet 24:21-25
41. Rajendrakumar CSV, Suryanarayana T, Reddy AR (1997) DNA helix destabilization by proline and betaine: possible role in the salinity tolerance process. FEBS Lett 410:201-205
42. Ronnow B, Kielland-Brandt MC (1993) GUT2, a gene for mitochondrial glycerol 3-phosphate dehydrogenase of Saccharomyces cerevisiae. Yeast 9:1121-1130
43. Rudolph AS, Crowe JH (1985) Membrane stabilization during freezing: the role of two natural cryoprotectants, trehalose and proline. Cryobiology 22:367-377
44. Samuel D, Kumar TKS, Ganesh G, Jayaraman G, Yang PW, Chang MM, Trivedi VD, Wang SL, Hwang KC, Chang DK, Yu C (2000) Proline inhibits aggregation during protein refolding. Protein Sci 9:344-352
45. Sekine T, Kawaguchi A, Hamano Y, Takagi H (2007) Desensitization of feedback inhibition of the Saccharomyces cerevisiae γ-glutamyl kinase enhances proline accumulation and freezing tolerance. Appl Environ Microbiol 73:4011-4019
46. Singer MA, Lindquist S (1998) Thermotolerance in Saccharomyces cerevisiae: the Yin and Yang of trehalose. Trends Biotechnol 16:460-468
47. Sumrada RA, Cooper TG (1984) Nucleotide sequence of the Saccharomyces cerevisiae arginase gene (CAR1) and its transcription under various physiological conditions. J Bacteriol 160:1078-1087
48. Takagi H, Iwamoto F, Nakamori S (1997) Isolation of freeze-tolerant laboratory strains of Saccharomyces cerevisiae from proline-analogue-resistant mutants. Appl Microbiol Biotechnol 47:405-411
49. Takagi H, Sakai K, Morida K, Nakamori S (2000) Proline accumulation by mutation or disruption of the proline oxidase gene improves resistance to freezing and desiccation stresses in Saccharomyces cerevisiae. FEMS Microbiol Lett 184:103-108
50. Takagi H, Takaoka M, Kawaguchi A, Kubo Y (2005) Effect of l-proline on sake brewing and ethanol stress in Saccharomyces cerevisiae. Appl Environ Microbiol 71:8656-8662
51. Tamás MJ, Luyten K, Sutherland FCW, Hernandez A, Albertyn J, Valadi H, Li H, Prior BA, Kilian SG, Ramos J, Gustafsson L, Thevelein JM, Hohmann S (1999) Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation. Mol Microbiol 31:1087-1104
52. Tamás MJ, Rep M, Thevelein JM, Hohmann S (2000) Stimulation of the yeast high osmolarity glycerol (HOG) pathway: evidence for a signal generated by a change in turgor rather than by water stress. FEBS Lett 472:159-165
53. Terao Y, Nakamori S, Takagi H (2003) Gene dosage effect of l-proline biosynthetic enzymes on l-proline accumulation and freeze tolerance in Saccharomyces cerevisiae. Appl Environ Microbiol 69:6527-6532
54. Thomas KC, Hynes SH, Ingledew WM (1994) Effects of particulate materials and osmoprotectants on very-high-gravity ethanolic fermentation by Saccharomyces cerevisiae. Appl Environ Microbiol 60:1519-1524
55. Tomenchok DM, Brandriss MC (1987) Gene-enzyme relationships in the proline biosynthetic pathway of Saccharomyces cerevisiae. J Bacteriol 169:5364-5372
56. Treger JM, Schmitt AP, Simon JR, McEntee K (1998) Transcriptional factor mutations reveal regulatory complexities of heat shock and newly identified stress genes in Saccharomyces cerevisiae. J Biol Chem 273:26875-26879
57. Van Dijck P, Colavizza D, Smet P, Thevelein JM (1995) Differential importance of trehalose in stress resistance in fermenting and nonfermenting Saccharomyces cerevisiae cells. Appl Environ Microbiol 61:109-115
58. Verbruggen N, Hua XJ, May M, Van Montagu M (1996) Environmental and developmental signals modulate proline homeostasis: evidence for a negative transcriptional regulator. Proc Natl Acad Sci U S A 93:8787-8791
59. Wang SS, Brandriss MC (1986) Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT1 gene. Mol Cell Biol 6:2638-2645